Cytosolic Phospholipase A2α Is Essential for Renal Dysfunction and End-Organ Damage Associated With Angiotensin II-Induced Hypertension

scientific article published on 4 June 2015

Cytosolic Phospholipase A2α Is Essential for Renal Dysfunction and End-Organ Damage Associated With Angiotensin II-Induced Hypertension is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/AJH/HPV083
P932PMC publication ID4751243
P698PubMed publication ID26045535

P50authorShyamala ThirunavukkarasuQ85315624
P2093author name stringJoseph V Bonventre
Kafait U Malik
Nayaab S Khan
Xiao R Fang
Chi Young Song
P2860cites workRole of thromboxane receptors in the dipsogenic response to central angiotensin II.Q43879276
Role of 20-hydroxyeicosatetraenoic acid in the renal and vasoconstrictor actions of angiotensin II.Q44031640
Cytosolic phospholipase A2 (cPLA2) regulation of human monocyte NADPH oxidase activity. cPLA2 affects translocation but not phosphorylation of p67(phox) and p47(phox).Q44052605
Norepinephrine-induced stimulation of p38 mitogen-activated protein kinase is mediated by arachidonic acid metabolites generated by activation of cytosolic phospholipase A(2) in vascular smooth muscle cellsQ44285572
12-Hydroxyeicosatetraenoic acid participates in angiotensin II afferent arteriolar vasoconstriction by activating L-type calcium channelsQ44570733
Cyclic stretch-induced cPLA2 mediates ERK 1/2 signaling in rabbit proximal tubule cellsQ44724752
Role for thromboxane receptors in angiotensin-II-induced hypertension.Q44725166
Characterization of murine vasopressor and vasodepressor prostaglandin E(2) receptors.Q52539292
Regulation of immune cells by eicosanoid receptors.Q53530676
Blood pressure-independent effects in rats with human renin and angiotensinogen genes.Q54062419
Role for endothelin-1 in angiotensin II-mediated hypertensionQ73532048
Renal oxygenases: differential contribution to vasoconstriction induced by ET-1 and ANG IIQ73569006
The pulsatility index and the resistive index in renal arteries. Associations with long-term progression in chronic renal failureQ73569397
Signal transduction mechanisms involved in angiotensin-(1-7)-stimulated arachidonic acid release and prostanoid synthesis in rabbit aortic smooth muscle cellsQ74064560
Increased glomerular cytosolic phospholipase A2 activity of OLETF rats with early diabetesQ78244904
Eicosanoids in the innate immune response: TLR and non-TLR routesQ27690699
20-HETE and blood pressure regulation: clinical implicationsQ28288942
Endothelin mediates some of the renal actions of acutely administered angiotensin IIQ28344593
Epoxides and soluble epoxide hydrolase in cardiovascular physiologyQ28396313
Angiotensin II-induced vascular smooth muscle cell migration and growth are mediated by cytochrome P450 1B1-dependent superoxide generationQ28571898
Alterations in renal cytosolic phospholipase A2 and cyclooxygenases in polycystic kidney diseaseQ28580281
P-450 metabolites of arachidonic acid in the control of cardiovascular functionQ29620578
Inflammation and mechanical stretch promote aortic stiffening in hypertension through activation of p38 mitogen-activated protein kinase.Q30589228
Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acidQ33612950
Pressure-induced renal injury in angiotensin II versus norepinephrine-induced hypertensive ratsQ33614801
Eicosanoid regulation of the renal vasculatureQ34093289
Inflammation, immunity, and hypertensionQ34528283
Effects of thromboxane synthase inhibition on vascular responsiveness in the in vivo rat mesenteryQ34569479
Cytosolic phospholipase A2α is critical for angiotensin II-induced hypertension and associated cardiovascular pathophysiologyQ35175554
Prostaglandin E-prostanoid4 receptor mediates angiotensin II-induced (pro)renin receptor expression in the rat renal medullaQ35654731
Cytochrome P450 1B1 contributes to renal dysfunction and damage caused by angiotensin II in miceQ35707118
Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting.Q35925625
Involvement of the intrarenal renin-angiotensin system in experimental models of glomerulonephritisQ36091351
Inactivation of the E-prostanoid 3 receptor attenuates the angiotensin II pressor response via decreasing arterial contractility.Q36591447
Roles of lipid mediators in kidney injury.Q36833405
Roles of the cytochrome P450 arachidonic acid monooxygenases in the control of systemic blood pressure and experimental hypertension.Q36863470
Arachidonic Acid metabolites in the cardiovascular system: the role of lipoxygenase isoforms in atherogenesis with particular emphasis on vascular remodelingQ37037140
Regulation of T-cell function by endogenously produced angiotensin II.Q37100479
T lymphocytes: a role in hypertension?Q37664405
Lipid-cytokine-chemokine cascades orchestrate leukocyte recruitment in inflammationQ37953364
Effect of prostaglandins on renal salt and water excretion.Q39587451
Control of sodium excretion by angiotensin II: intrarenal mechanisms and blood pressure regulationQ39735386
Cytosolic phospholipase A2alpha is targeted to the p47phox-PX domain of the assembled NADPH oxidase via a novel binding site in its C2 domainQ39944302
Prostaglandins, prostacyclin, and thromboxanesQ40306987
Activation of cytosolic phospholipase A2 in human T-lymphocytes involves inhibitor-kappaB and mitogen-activated protein kinasesQ40658050
The kidney in blood pressure regulation and development of hypertensionQ41600678
Arthur C. Corcoran Memorial Lecture. The role of eicosanoids in angiotensin-dependent hypertensionQ41695612
Complement-induced phospholipase A2 activation in experimental membranous nephropathyQ42485155
Renal concentrating defect in mice lacking group IV cytosolic phospholipase A(2).Q42501163
P433issue2
P304page(s)258-265
P577publication date2015-06-04
P1433published inJournal of Clinical HypertensionQ15762840
P1476titleCytosolic Phospholipase A2α Is Essential for Renal Dysfunction and End-Organ Damage Associated With Angiotensin II-Induced Hypertension
P478volume29

Reverse relations

cites work (P2860)
Q47681288Bone marrow-derived cPLA2α contributes to renal fibrosis progression.
Q47859985Brain Cytosolic Phospholipase A2α Mediates Angiotensin II-Induced Hypertension and Reactive Oxygen Species Production in Male Mice
Q38750539Cytosolic phospholipase A2α increases proliferation and de-differentiation of human renal tubular epithelial cells
Q89994115Targeting ROS and cPLA2/COX2 Expressions Ameliorated Renal Damage in Obese Mice with Endotoxemia

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