scholarly article | Q13442814 |
P356 | DOI | 10.1007/S00018-007-6527-Y |
P8608 | Fatcat ID | release_f2rgupss4jg3xmksqraikbdq2a |
P932 | PMC publication ID | 3383618 |
P698 | PubMed publication ID | 17364144 |
P5875 | ResearchGate publication ID | 6443363 |
P50 | author | Clare M. Lloyd | Q56992813 |
P2093 | author name string | S G Trivedi | |
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Bertilimumab Cambridge Antibody Technology Group | Q28295955 | ||
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Requirement for IL-13 independently of IL-4 in experimental asthma | Q41881960 | ||
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The Coordinated Action of CC Chemokines in the Lung Orchestrates Allergic Inflammation and Airway Hyperresponsiveness | Q42417164 | ||
Platelet-activating factor-induced human eosinophil activation. Generation and release of cyclo-oxygenase metabolites in human blood eosinophils from asthmatics. | Q42511110 | ||
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Targeted disruption of the chemokine eotaxin partially reduces antigen-induced tissue eosinophilia | Q42947733 | ||
TGF-beta1 causes airway fibrosis and increased collagen I and III mRNA in mice | Q43059347 | ||
Regulation of lymphocyte proliferation by eosinophils via chymotrypsin-like protease activity and adhesion molecule interaction | Q43264612 | ||
Receptor internalization is required for eotaxin-induced responses in human eosinophils | Q44281045 | ||
Differential regulation of human eosinophil IL-3, IL-5, and GM-CSF receptor alpha-chain expression by cytokines: IL-3, IL-5, and GM-CSF down-regulate IL-5 receptor alpha expression with loss of IL-5 responsiveness, but up-regulate IL-3 receptor alph | Q44448872 | ||
Allergen-induced fluctuation in CC chemokine receptor 3 expression on bone marrow CD34+ cells from asthmatic subjects: significance for mobilization of haemopoietic progenitor cells in allergic inflammation | Q44518704 | ||
Compound exocytosis and cumulative fusion in eosinophils | Q44552155 | ||
Role of interleukin-5 and eosinophils in allergen-induced airway remodeling in mice | Q44771554 | ||
Interleukin-13 Induces Proliferation of Human Airway Epithelial CellsIn Vitrovia a Mechanism Mediated by Transforming Growth Factor- α | Q44876815 | ||
Allergen stimulates bone marrow CD34(+) cells to release IL-5 in vitro; a mechanism involved in eosinophilic inflammation? | Q45050078 | ||
2B4 (CD244) is expressed and functional on human eosinophils | Q45195916 | ||
Muscarinic M3 receptors mediate contraction of human central and peripheral airway smooth muscle | Q45270945 | ||
Inhibition of eosinophil rolling and recruitment in P-selectin- and intracellular adhesion molecule-1-deficient mice | Q46233274 | ||
Discovery of CC chemokine receptor-3 (CCR3) antagonists with picomolar potency. | Q46383173 | ||
Damage to schistosomula of Schistosoma mansoni induced directly by eosinophil major basic protein | Q46502189 | ||
Conserved structure and tissue expression of rat eotaxin | Q46847625 | ||
Fibroblast growth factor 2 and transforming growth factor beta1 synergism in human bronchial smooth muscle cell proliferation | Q46913829 | ||
The chemokine, eotaxin, activates guinea-pig eosinophils in vitro and causes their accumulation into the lung in vivo | Q46987094 | ||
Effects of a low-molecular-weight CCR-3 antagonist on chronic experimental asthma | Q47325098 | ||
A novel T cell-regulated mechanism modulating allergen-induced airways hyperreactivity in BALB/c mice independently of IL-4 and IL-5 | Q47756902 | ||
Gradual increase in priming of human eosinophils during extravasation from peripheral blood to the airways in response to allergen challenge | Q47803593 | ||
Eotaxin-2 and eotaxin-3 expression is associated with persistent eosinophilic bronchial inflammation in patients with asthma after allergen challenge. | Q47821478 | ||
Airway remodelling in asthma: models and supermodels? | Q47845487 | ||
Markers of eosinophilic inflammation and tissue re-modelling in children before clinically diagnosed bronchial asthma | Q47853684 | ||
Increased eosinophil-lineage committed progenitors in the lung of allergen-challenged mice | Q47869342 | ||
A critical role for eosinophils in allergic airways remodeling | Q47925478 | ||
Defining a link with asthma in mice congenitally deficient in eosinophils. | Q47925494 | ||
Anti–IL-5 (mepolizumab) therapy induces bone marrow eosinophil maturational arrest and decreases eosinophil progenitors in the bronchial mucosa of atopic asthmatics | Q47963812 | ||
Mouse Eotaxin expression parallels eosinophil accumulation during lung allergic inflammation but it is not restricted to a Th2-type response | Q48067938 | ||
Role of ADAM8 in experimental asthma | Q48774746 | ||
Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study. | Q49032278 | ||
SNARE proteins are critical for regulated exocytosis of ECP from human eosinophils | Q49064640 | ||
IL-11 expression is increased in severe asthma: association with epithelial cells and eosinophils | Q50232593 | ||
Nerve growth factor is preformed in and activates human peripheral blood eosinophils | Q50522335 | ||
Expression of transforming growth factors-alpha and beta 1 messenger RNA and product by eosinophils in nasal polyps | Q50772939 | ||
CC Chemokine Ligand 1 Promotes Recruitment of Eosinophils But Not Th2 Cells During the Development of Allergic Airways Disease | Q51676560 | ||
Mast-cell infiltration of airway smooth muscle in asthma | Q51715332 | ||
Identification of interleukin-2 in human peripheral blood eosinophils | Q52519848 | ||
The eotaxin chemokines and CCR3 are fundamental regulators of allergen-induced pulmonary eosinophilia | Q53654624 | ||
Regulation of B lymphocyte and macrophage development by graded expression of PU.1. | Q55033922 | ||
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Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects | Q55094051 | ||
Human eosinophils release matrix metalloproteinase-9 on stimulation with TNF-alpha | Q56752153 | ||
Eosinophil degranulation: an evolutionary vestige or a universally destructive effector function? | Q36239677 | ||
Eosinophilia in transgenic mice expressing interleukin 5. | Q36353850 | ||
The contribution of transforming growth factor-beta and epidermal growth factor signalling to airway remodelling in chronic asthma | Q36357991 | ||
Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo | Q36365726 | ||
Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model | Q36366104 | ||
Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. | Q36366158 | ||
Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo | Q36369717 | ||
Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma | Q36369722 | ||
T helper cell type 2 cytokine-mediated comitogenic responses and CCR3 expression during differentiation of human mast cells in vitro | Q36375111 | ||
CC chemokine receptor (CCR)3/eotaxin is followed by CCR4/monocyte-derived chemokine in mediating pulmonary T helper lymphocyte type 2 recruitment after serial antigen challenge in vivo | Q36375742 | ||
Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma | Q36377337 | ||
Kinetics of eotaxin generation and its relationship to eosinophil accumulation in allergic airways disease: analysis in a guinea pig model in vivo | Q36380566 | ||
Mechanisms of Acute Eosinophil Mobilization from the Bone Marrow Stimulated by Interleukin 5: The Role of Specific Adhesion Molecules and Phosphatidylinositol 3-Kinase | Q36401641 | ||
Eosinophilic airway disorders | Q36448420 | ||
The asthma epidemic | Q36662046 | ||
Cysteinyl leukotriene 1 receptor controls the severity of chronic pulmonary inflammation and fibrosis | Q36853612 | ||
Lymph node trafficking and antigen presentation by endobronchial eosinophils | Q37176309 | ||
Eosinophil recruitment to the lung in a murine model of allergic inflammation. The role of T cells, chemokines, and adhesion receptors | Q37361509 | ||
Relationship between interleukin-5 and eotaxin in regulating blood and tissue eosinophilia in mice | Q37364684 | ||
High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines. | Q37371775 | ||
Allergen-induced increases in IL-5 receptor alpha-subunit expression on bone marrow-derived CD34+ cells from asthmatic subjects. A novel marker of progenitor cell commitment towards eosinophilic differentiation | Q37374729 | ||
Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice | Q37380666 | ||
Myofibroblasts differentiate from fibroblasts when plated at low density | Q37633281 | ||
Mediators of hypersensitivity and inflammatory cells in the pathogenesis of bronchial asthma | Q40210092 | ||
Eosinophil-derived cationic proteins activate the synthesis of remodeling factors by airway epithelial cells | Q40230341 | ||
Cutting edge: human eosinophils regulate T cell subset selection through indoleamine 2,3-dioxygenase | Q40495420 | ||
Inhibition of airway remodeling in IL-5-deficient mice | Q40553706 | ||
Inhibitory role of eosinophils on cell surface plasmin generation by bronchial epithelial cells: inhibitory effects of transforming growth factor beta | Q40789221 | ||
CC chemokine receptor-3 undergoes prolonged ligand-induced internalization | Q40959278 | ||
Asthma. From bronchoconstriction to airways inflammation and remodeling | Q33915771 | ||
Murine eotaxin: an eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppression | Q33941230 | ||
New aspects of degranulation and fates of airway mucosal eosinophils | Q33942417 | ||
Degranulation patterns of eosinophil granulocytes as determinants of eosinophil driven disease | Q33943245 | ||
The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness | Q34009861 | ||
IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines | Q34090258 | ||
Human eosinophils express functional interleukin 2 receptors | Q34197541 | ||
Elemental signals regulating eosinophil accumulation in the lung. | Q34211465 | ||
IL-5-induced airway eosinophilia--the key to asthma? | Q34211474 | ||
Expression of membrane type-4 matrix metalloproteinase (metalloproteinase-17) by human eosinophils | Q34228911 | ||
Stimulation of basophil and rat mast cell histamine release by eosinophil granule-derived cationic proteins | Q34250409 | ||
Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation | Q34326460 | ||
Eosinophils function as antigen-presenting cells | Q34329153 | ||
The trials and tribulations of IL-5, eosinophils, and allergic asthma | Q34394617 | ||
The eosinophil | Q34503956 | ||
Making eosinophils through subtle shifts in transcription factor expression | Q34667489 | ||
Localized eosinophil degranulation mediates disease in tropical pulmonary eosinophilia | Q34713307 | ||
Effects of eosinophils on mast cells: a new pathway for the perpetuation of allergic inflammation | Q34825566 | ||
Inflammatory cells in asthma: mechanisms and implications for therapy | Q35047387 | ||
Airway hyperresponsiveness | Q35082509 | ||
Understanding exocytosis in immune and inflammatory cells: the molecular basis of mediator secretion | Q35126066 | ||
A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation | Q35133853 | ||
Eosinophils and cysteinyl leukotrienes. | Q35190750 | ||
Chemokines in allergic airway disease. | Q35193668 | ||
Purification of human eosinophil-derived neurotoxin | Q35468177 | ||
Human eosinophils can express the cytokines tumor necrosis factor-alpha and macrophage inflammatory protein-1 alpha | Q35611042 | ||
The role of eosinophils in host defense against helminth parasites | Q35624885 | ||
Time to draw breath: asthma-susceptibility genes are identified | Q35773264 | ||
Nerve growth factor displays stimulatory effects on human skin and lung fibroblasts, demonstrating a direct role for this factor in tissue repair | Q35932924 | ||
Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice | Q35955690 | ||
Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics | Q36001230 | ||
Enhanced upregulation of smooth muscle related transcripts by TGF beta2 in asthmatic (myo) fibroblasts | Q36183983 | ||
Prolonged allergen challenge in mice leads to persistent airway remodelling. | Q36193173 | ||
Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system | Q36228614 | ||
Epithelial-mesenchymal communication in the pathogenesis of chronic asthma | Q36236793 | ||
PDGF-A Signaling Is a Critical Event in Lung Alveolar Myofibroblast Development and Alveogenesis | Q57415025 | ||
Increases in eotaxin-positive cells in induced sputum from atopic asthmatic subjects after inhalational allergen challenge | Q57415813 | ||
The Relationship Between Allergen-Induced Tissue Eosinophilia and Markers of Repair and Remodeling in Human Atopic Skin | Q57966311 | ||
Eosinophil cationic protein alters proteoglycan metabolism in human lung fibroblast cultures | Q68003083 | ||
Human eosinophils synthesize and secrete interleukin-6, in vitro | Q68039348 | ||
Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma | Q68052191 | ||
In vivo priming of platelet-activating factor-induced eosinophil chemotaxis in allergic asthmatic individuals | Q68090195 | ||
T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma | Q68294272 | ||
Differential sensitivities of purified human eosinophils and neutrophils to defined chemotaxins | Q69351581 | ||
Elevated levels of the eosinophil granule major basic protein in the sputum of patients with bronchial asthma | Q70770268 | ||
Human eosinophils express messenger RNA encoding RANTES and store and release biologically active RANTES protein | Q70911250 | ||
Increased MCP-1, RANTES, and MIP-1alpha in bronchoalveolar lavage fluid of allergic asthmatic patients | Q71046247 | ||
Strongyloides stercoralis: eosinophil-dependent immune-mediated killing of third stage larvae in BALB/cByJ mice | Q71080603 | ||
Constitutive production of IL-4 and IL-10 and stimulated production of IL-8 by normal peripheral blood eosinophils | Q71120610 | ||
Human eosinophils elaborate the lymphocyte chemoattractants. IL-16 (lymphocyte chemoattractant factor) and RANTES | Q71483496 | ||
Hematopoiesis in mice lacking the entire granulocyte-macrophage colony-stimulating factor/interleukin-3/interleukin-5 functions | Q71611722 | ||
Eosinophil granule proteins increase microvascular macromolecular transport in the hamster cheek pouch | Q71644388 | ||
Recombinant human eotaxin induces oxygen radical production, Ca(2+)-mobilization, actin reorganization, and CD11b upregulation in human eosinophils via a pertussis toxin-sensitive heterotrimeric guanine nucleotide-binding protein | Q71692466 | ||
Increased levels of CD34+ hemopoietic progenitor cells in atopic subjects | Q71778422 | ||
Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia | Q71994193 | ||
Distinct immunohistochemical localization of IL-4 in human inflamed airway tissues. IL-4 is localized to eosinophils in vivo and is released by peripheral blood eosinophils | Q72056200 | ||
IL-8 is expressed by human peripheral blood eosinophils. Evidence for increased secretion in asthma | Q72191734 | ||
Pretreatment with an antibody to interleukin-5 prevents loss of pulmonary M2 muscarinic receptor function in antigen-challenged guinea pigs | Q72584587 | ||
Eosinophil major basic protein-1 does not contribute to allergen-induced airway pathologies in mouse models of asthma | Q73163088 | ||
Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells | Q73202021 | ||
Expression and regulation of monocyte chemoattractant protein-1 by human eosinophils | Q73295944 | ||
Resolution of bronchial hyperresponsiveness and pulmonary inflammation is associated with IL-3 and tissue leukocyte apoptosis | Q73400847 | ||
Expression of vascular endothelial growth factor, basic fibroblast growth factor, and angiogenin immunoreactivity in asthmatic airways and its relationship to angiogenesis | Q73431447 | ||
Localization of eosinophils to airway nerves and effect on neuronal M2 muscarinic receptor function | Q73575778 | ||
Interleukin-2 inhibits eosinophil migration but is counteracted by IL-5 priming | Q73622099 | ||
Eosinophil-associated TGF- β1mRNA Expression and Airways Fibrosis in Bronchial Asthma | Q73728083 | ||
Release of RANTES, MIP-1 α , and MCP-1 into Asthmatic Airways Following Endobronchial Allergen Challenge | Q73885831 | ||
Migration of eosinophils through basement membrane components in vitro: role of matrix metalloproteinase-9 | Q73893710 | ||
The chemotactic cytokine eotaxin acts as a granulocyte-macrophage colony-stimulating factor during lung inflammation | Q74270275 | ||
Eotaxin induces a rapid release of eosinophils and their progenitors from the bone marrow | Q74357254 | ||
Role of interleukin-13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthma | Q74417771 | ||
Eosinophils promote allergic disease of the lung by regulating CD4(+) Th2 lymphocyte function | Q74481539 | ||
The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma | Q74595761 | ||
Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells | Q74595805 | ||
Endogenous platelet-activating factor is critically involved in effector functions of eosinophils stimulated with IL-5 or IgG | Q74595915 | ||
Matrix metalloproteinase-9 deficiency results in enhanced allergen-induced airway inflammation | Q75424883 | ||
Intracellular localization and release of eotaxin from normal eosinophils | Q77317884 | ||
IL-4 and IL-13 specifically increase adhesion molecule and inflammatory cytokine expression in human lung fibroblasts | Q77492715 | ||
CD34(+)/interleukin-5Ralpha messenger RNA+ cells in the bronchial mucosa in asthma: potential airway eosinophil progenitors | Q77742474 | ||
The biologic role of interleukin-8: functional analysis and expression of CXCR1 and CXCR2 on human eosinophils | Q77784712 | ||
P433 | issue | 10 | |
P921 | main subject | pathogenesis | Q372016 |
P304 | page(s) | 1269-1289 | |
P577 | publication date | 2007-05-01 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | Cellular and Molecular Life Sciences | Q5058352 |
P1476 | title | Eosinophils in the pathogenesis of allergic airways disease | |
P478 | volume | 64 |
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