A Role for the Fifth G-Track in G-Quadruplex Forming Oncogene Promoter Sequences during Oxidative Stress: Do These "Spare Tires" Have an Evolved Function?

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A Role for the Fifth G-Track in G-Quadruplex Forming Oncogene Promoter Sequences during Oxidative Stress: Do These "Spare Tires" Have an Evolved Function? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/ACSCENTSCI.5B00202
P932PMC publication ID4571166
P698PubMed publication ID26405692
P5875ResearchGate publication ID282251747

P50authorCynthia J. BurrowsQ28823528
Susan S WallaceQ41886664
Jia ZhouQ42552991
P2093author name stringAaron M Fleming
P2860cites workFacilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agentsQ24816211
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The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivoQ28586574
Base-excision repair of oxidative DNA damageQ29615373
Mechanisms for DNA charge transportQ33887276
Base excision repair: a critical player in many gamesQ33908163
N6-methyladenine DNA modification in DrosophilaQ34043900
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Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?Q34174883
Making sense of G‐quadruplex and i‐motif functions in oncogene promotersQ34271763
DNA replication stress, genome instability and agingQ34720959
The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structuresQ35562087
Functional complexity and regulation through RNA dynamicsQ35872580
Quadruplex-single nucleotide polymorphisms (Quad-SNP) influence gene expression difference among individuals.Q35956042
Promoter G-quadruplex sequences are targets for base oxidation and strand cleavage during hypoxia-induced transcriptionQ36040836
Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancerQ36079440
Thermodynamic consequences of the hyperoxidized guanine lesion guanidinohydantoin in duplex DNAQ36189537
Populated intermediates in the thermal unfolding of the human telomeric quadruplexQ36337174
Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeuticsQ36959489
8-oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factorsQ37619953
DNA secondary structures and epigenetic determinants of cancer genome evolutionQ37657891
Folding and unfolding pathways of the human telomeric G-quadruplexQ37672413
Folding pathways of human telomeric type-1 and type-2 G-quadruplex structures.Q38340450
Effects of site-specific guanine C8-modifications on an intramolecular DNA G-quadruplexQ38699075
Rates of chemical cleavage of DNA and RNA oligomers containing guanine oxidation productsQ39020441
Paradoxical hotspots for guanine oxidation by a chemical mediator of inflammationQ40271694
G-quadruplex folds of the human telomere sequence alter the site reactivity and reaction pathway of guanine oxidation compared to duplex DNA.Q41788288
Oxidative stress regulates vascular endothelial growth factor-A gene transcription through Sp1- and Sp3-dependent activation of two proximal GC-rich promoter elementsQ42435325
The disruptive positions in human G-quadruplex motifs are less polymorphic and more conserved than their neutral counterpartsQ42582885
Spontaneous DNA lesions modulate DNA structural transitions occurring at nuclease hypersensitive element III(1) of the human c-myc proto-oncogeneQ47662696
G-rich proto-oncogenes are targeted for genomic instability in B-cell lymphomas.Q55043612
Intramolecular folding in three tandem guanine repeats of human telomeric DNAQ56891402
Unfolding of G-quadruplexes: energetic, and ion and water contributions of G-quartet stackingQ83001606
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)226-233
P577publication date2015-07-06
P1433published inACS Central ScienceQ27726586
P1476titleA Role for the Fifth G-Track in G-Quadruplex Forming Oncogene Promoter Sequences during Oxidative Stress: Do These "Spare Tires" Have an Evolved Function?
P478volume1

Reverse relations

cites work (P2860)
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