Novel Roles of Epoxyeicosanoids in Regulating Cardiac Mitochondria

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Novel Roles of Epoxyeicosanoids in Regulating Cardiac Mitochondria is …
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scholarly articleQ13442814

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P819ADS bibcode2016PLoSO..1160380E
P356DOI10.1371/JOURNAL.PONE.0160380
P932PMC publication ID4975494
P698PubMed publication ID27494529

P2093author name stringJohn R Falck
John M Seubert
Nasser Alsaleh
Rambabu Dakarapu
Haitham E El-Sikhry
P2860cites workStandardized mitochondrial analysis gives new insights into mitochondrial dynamics and OPA1 function.Q53178718
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The BH3-only Bnip3 binds to the dynamin Opa1 to promote mitochondrial fragmentation and apoptosis by distinct mechanismsQ24309355
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The pathways of mitophagy for quality control and clearance of mitochondriaQ27009206
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Targeting myocardial substrate metabolism in heart failure: potential for new therapiesQ27694733
Aconitase couples metabolic regulation to mitochondrial DNA maintenanceQ27939485
OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demandQ28249429
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OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusionQ28251846
Formation of elongated giant mitochondria in DFO-induced cellular senescence: involvement of enhanced fusion process through modulation of Fis1Q28255413
Molecular mechanisms mediating mitochondrial dynamics and mitophagy and their functional roles in the cardiovascular systemQ28384316
Cell biology. Metabolic control of cell deathQ28397089
Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodelingQ28506506
SLP-2 is required for stress-induced mitochondrial hyperfusionQ28594182
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.Q29616569
Impaired OMA1-dependent cleavage of OPA1 and reduced DRP1 fission activity combine to prevent mitophagy in cells that are dependent on oxidative phosphorylationQ30578089
Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cellsQ33341058
Epoxyeicosatrienoic acids limit damage to mitochondrial function following stress in cardiac cells.Q33418150
Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1.Q33936625
Cristae formation-linking ultrastructure and function of mitochondriaQ34012730
PPARγ signaling is required for mediating EETs protective effects in neonatal cardiomyocytes exposed to LPSQ34488280
Action of epoxyeicosatrienoic acids on cellular functionQ34567484
Cardioprotective effect of a dual acting epoxyeicosatrienoic acid analogue towards ischaemia reperfusion injuryQ34588685
A time to reap, a time to sow: mitophagy and biogenesis in cardiac pathophysiologyQ34716974
Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvationQ35064216
Persistent mitochondrial hyperfusion promotes G2/M accumulation and caspase-dependent cell deathQ35121876
Transcriptional regulatory circuits controlling mitochondrial biogenesis and functionQ35683727
Mitochondria and the aging heartQ36077249
Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiencyQ37215027
Overexpression of CYP2J2 provides protection against doxorubicin-induced cardiotoxicityQ37264451
Importance of lipid metabolism for intracellular and mitochondrial membrane fusion/fission processesQ37585737
OPA1 (dys)functions.Q37665952
Mitochondrial turnover in the heartQ37819319
The role of SirT1 in muscle mitochondrial turnoverQ37853240
Mitochondria and heart diseaseQ37991639
Mitochondrial morphology in mitophagy and macroautophagyQ37992366
Dominant optic atrophy, OPA1, and mitochondrial quality control: understanding mitochondrial network dynamicsQ38143285
Mitochondrial cardiomyopathy: pathophysiology, diagnosis, and managementQ38148105
PPARs and ERRs: molecular mediators of mitochondrial metabolismQ38285171
Integrating mitochondrial translation into the cellular contextQ38624841
Cigarette smoke extract affects mitochondrial function in alveolar epithelial cellsQ38946835
Epoxyeicosatrienoic acids protect cardiac cells during starvation by modulating an autophagic responseQ39070894
The antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shockQ39349684
PPARgamma stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell lossQ39851448
Giant mitochondria do not fuse and exchange their contents with normal mitochondriaQ40061383
The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco/endoplasmic reticulum calcium storesQ40125863
Regulation of fatty acid oxidation in the mammalian heart in health and diseaseQ40682538
The intracellular redox state is a core determinant of mitochondrial fusionQ42045452
Eicosapentaenoic acid increases cytochrome P-450 2J2 gene expression and epoxyeicosatrienoic acid production via peroxisome proliferator-activated receptor γ in endothelial cellsQ43234460
Characterization of OPA1 isoforms isolated from mouse tissuesQ44071219
Novel soluble epoxide hydrolase inhibitor protects mitochondrial function following stressQ44113614
Modulation of Lon protease activity and aconitase turnover during aging and oxidative stress.Q44234584
Cells die with increased cytosolic ATP during apoptosis: a bioluminescence study with intracellular luciferaseQ46500205
Uncoupling protein 3 protects aconitase against inactivation in isolated skeletal muscle mitochondriaQ46638107
Apoptosis and necrosis: intracellular ATP level as a determinant for cell death modesQ47956069
14,15-EET promotes mitochondrial biogenesis and protects cortical neurons against oxygen/glucose deprivation-induced apoptosis.Q48714610
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)e0160380
P577publication date2016-08-05
P1433published inPLOS OneQ564954
P1476titleNovel Roles of Epoxyeicosanoids in Regulating Cardiac Mitochondria
P478volume11

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Q45968248Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function.

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