The antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shock

scientific article published on 8 May 2012

The antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shock is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BBABIO.2012.05.001
P932PMC publication ID3686154
P698PubMed publication ID22579715
P5875ResearchGate publication ID224948968

P2093author name stringLuca Scorrano
Luiza K Sanjuán Szklarz
P2860cites workOPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28Q24290356
Control of mitochondrial morphology by a human mitofusinQ24290831
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cellsQ24291591
The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1Q24308767
Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cellsQ24315625
Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosisQ24338169
OPA1 requires mitofusin 1 to promote mitochondrial fusionQ24560014
Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosisQ24562044
Fission and selective fusion govern mitochondrial segregation and elimination by autophagyQ24652230
Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphologyQ24675079
Mitochondrial membrane remodelling regulated by a conserved rhomboid proteaseQ27935531
Loss of Drp1 function alters OPA1 processing and changes mitochondrial membrane organizationQ47900211
Organelle isolation: functional mitochondria from mouse liver, muscle and cultured filroblastsQ60056610
A mutation in the yeast heat-shock factor gene causes temperature-sensitive defects in both mitochondrial protein import and the cell cycleQ27936788
Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophyQ28140286
Negative regulation of the Apaf-1 apoptosome by Hsp70Q28143100
hFis1, a novel component of the mammalian mitochondrial fission machineryQ28208369
PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2Q28221207
OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusionQ28251846
Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodelingQ28506506
Regulation of mitochondrial morphology through proteolytic cleavage of OPA1Q28571639
Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1Q28594164
SLP-2 is required for stress-induced mitochondrial hyperfusionQ28594182
Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cellsQ28854600
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARLQ29615624
Disruption of fusion results in mitochondrial heterogeneity and dysfunctionQ29616566
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosisQ29616568
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.Q29616569
A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosisQ29620536
Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerizationQ30485835
Hsp27 negatively regulates cell death by interacting with cytochrome c.Q33917298
Regulation of skeletal muscle oxidative capacity and insulin signaling by the mitochondrial rhomboid protease PARL.Q34113727
Intramembrane proteolysis: theme and variations.Q34342964
Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuliQ34605764
A cut short to death: Parl and Opa1 in the regulation of mitochondrial morphology and apoptosisQ34623508
Hax1 lacks BH modules and is peripherally associated to heavy membranes: implications for Omi/HtrA2 and PARL activity in the regulation of mitochondrial stress and apoptosisQ34991732
OPA1 processing reconstituted in yeast depends on the subunit composition of the m-AAA protease in mitochondriaQ35949122
OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L.Q36119045
Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavageQ36119051
Death versus survival: functional interaction between the apoptotic and stress-inducible heat shock protein pathwaysQ36274956
Quality control of mitochondria: protection against neurodegeneration and ageingQ36446844
Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusionQ37365417
The changing shape of mitochondrial apoptosisQ37568897
The heat shock response: life on the verge of deathQ37802041
Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphologyQ40227379
Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, and fission of mitochondriaQ40763148
Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neuronsQ41791615
The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible eventQ41837258
Traveling Bax and forth from mitochondria to control apoptosis.Q41869309
Processing of the dynamin Msp1p in S. pombe reveals an evolutionary switch between its orthologs Mgm1p in S. cerevisiae and OPA1 in mammals.Q42973575
Characterization of OPA1 isoforms isolated from mouse tissuesQ44071219
Cytosolic heat shock protein 60, hypoxia, and apoptosisQ44220806
Normal mitochondrial dynamics requires rhomboid-7 and affects Drosophila lifespan and neuronal functionQ47070303
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)1886-1893
P577publication date2012-05-08
P1433published inBiochimica et Biophysica ActaQ864239
P1476titleThe antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shock
P478volume1817

Reverse relations

cites work (P2860)
Q46471274Altered Mitochondrial Anatomy of Trigeminal Ganglia Neurons in Diabetes.
Q37431102Common variants in the PARL and PINK1 genes increase the risk to leprosy in Han Chinese from South China.
Q41100689Entamoeba histolytica rhomboid protease 1 has a role in migration and motility as validated by two independent genetic approaches
Q38611106Fusion or Fission: The Destiny of Mitochondria In Traumatic Brain Injury of Different Severities.
Q38122700Keeping mitochondria in shape: a matter of life and death
Q42381310Mitochondrial dysfunction in an Opa1(Q285STOP) mouse model of dominant optic atrophy results from Opa1 haploinsufficiency.
Q37686255Mitochondrial fusion and fission proteins: novel therapeutic targets for combating cardiovascular disease.
Q36096020Novel Roles of Epoxyeicosanoids in Regulating Cardiac Mitochondria
Q42704462Quercetin glycosides induced neuroprotection by changes in the gene expression in a cellular model of Parkinson's disease
Q46648250Rhomboid family gene expression profiling in breast normal tissue and tumor samples
Q46479013Role of dynamin-related protein 1-mediated mitochondrial fission in resistance of mouse C2C12 myoblasts to heat injury
Q38798007Stress-induced OMA1 activation and autocatalytic turnover regulate OPA1-dependent mitochondrial dynamics
Q52317009The Endoplasmic Reticulum Stress Response in Neuroprogressive Diseases: Emerging Pathophysiological Role and Translational Implications.

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