| P50 | author | Donald D Newmeyer | Q82635337 |
| | Marcela Votruba | Q56469509 |
| | Alexander Y. Andreyev | Q58048217 |
| P2093 | author name string | T Kuwana | |
| | Y Seong | |
| | W B Kiosses | |
| | Y Kushnareva | |
| P2860 | cites work | The effect of OPA1 on mitochondrial Ca²⁺ signaling | Q21135012 |
| | OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes | Q24304868 |
| | Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis | Q24338169 |
| | Opa1 deficiency in a mouse model of autosomal dominant optic atrophy impairs mitochondrial morphology, optic nerve structure and visual function | Q80146686 |
| | Preparation, culture, and immortalization of mouse embryonic fibroblasts | Q80674195 |
| | Defective mitochondrial fusion, altered respiratory function, and distorted cristae structure in skin fibroblasts with heterozygous OPA1 mutations | Q84577155 |
| | Characterization of Ca2+ signalling in postnatal mouse retinal ganglion cells: involvement of OPA1 in Ca2+ clearance | Q43070109 |
| | Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis. | Q43099640 |
| | Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria | Q44768454 |
| | OPA1 deficiency associated with increased autophagy in retinal ganglion cells in a murine model of dominant optic atrophy. | Q46113788 |
| | OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion | Q46789094 |
| | The human OPA1delTTAG mutation induces premature age-related systemic neurodegeneration in mouse. | Q48248957 |
| | Opa1 is essential for retinal ganglion cell synaptic architecture and connectivity. | Q48679280 |
| | Endoplasmic reticulum stress-induced apoptosis requires bax for commitment and Apaf-1 for execution in primary neurons. | Q50913051 |
| | OPA1 mutations in patients with autosomal dominant optic atrophy and evidence for semi-dominant inheritance | Q74147611 |
| | Effects of OPA1 mutations on mitochondrial morphology and apoptosis: relevance to ADOA pathogenesis | Q79432048 |
| | Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis | Q24562044 |
| | Fission and selective fusion govern mitochondrial segregation and elimination by autophagy | Q24652230 |
| | Deletion of the OPA1 gene in a dominant optic atrophy family: evidence that haploinsufficiency is the cause of disease | Q24679112 |
| | Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis | Q28240946 |
| | OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand | Q28249429 |
| | OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion | Q28251846 |
| | A novel deletion in the GTPase domain of OPA1 causes defects in mitochondrial morphology and distribution, but not in function | Q28289677 |
| | Bax activation initiates the assembly of a multimeric catalyst that facilitates Bax pore formation in mitochondrial outer membranes | Q28483986 |
| | Mfn2 modulates the UPR and mitochondrial function via repression of PERK | Q28589398 |
| | Disruption of fusion results in mitochondrial heterogeneity and dysfunction | Q29616566 |
| | Nonsense-mediated mRNA decay in health and disease | Q29619553 |
| | Dominant optic atrophy. | Q30459784 |
| | Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization | Q30485835 |
| | Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity | Q30532888 |
| | OPA1 mutations cause cytochrome c oxidase deficiency due to loss of wild-type mtDNA molecules | Q33980340 |
| | Increased optic atrophy type 1 expression protects retinal ganglion cells in a mouse model of glaucoma | Q34001754 |
| | Mitochondrial optic neuropathies - disease mechanisms and therapeutic strategies | Q34152110 |
| | Higd-1a interacts with Opa1 and is required for the morphological and functional integrity of mitochondria | Q34359338 |
| | Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis | Q34384160 |
| | The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells | Q35083432 |
| | A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics | Q35657086 |
| | The impact of the unfolded protein response on human disease | Q36062081 |
| | OPA1 mutation and late-onset cardiomyopathy: mitochondrial dysfunction and mtDNA instability | Q36522684 |
| | Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency | Q37215027 |
| | Caspase-independent mitochondrial cell death results from loss of respiration, not cytotoxic protein release. | Q37448270 |
| | OPA1 functions in mitochondria and dysfunctions in optic nerve. | Q37457225 |
| | OPA1-associated disorders: phenotypes and pathophysiology. | Q37457238 |
| | Bioenergetics and cell death. | Q37774677 |
| | Mouse models of dominant optic atrophy: what do they tell us about the pathophysiology of visual loss? | Q37783778 |
| | Mitochondrial Cristae: Where Beauty Meets Functionality. | Q38726665 |
| | The antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shock | Q39349684 |
| | Secondary mtDNA defects do not cause optic nerve dysfunction in a mouse model of dominant optic atrophy | Q39951945 |
| | A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy. | Q40240586 |
| | Low reserve of cytochrome c oxidase capacity in vivo in the respiratory chain of a variety of human cell types. | Q40993797 |
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P921 | main subject | haploinsufficiency | Q852654 |
| | optic atrophy | Q3629049 |
| P304 | page(s) | e2309 | |
| P577 | publication date | 2016-07-28 | |
| P1433 | published in | Cell Death and Disease | Q2197222 |
| P1476 | title | Mitochondrial dysfunction in an Opa1(Q285STOP) mouse model of dominant optic atrophy results from Opa1 haploinsufficiency | |
| P478 | volume | 7 | |