The basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression

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The basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression is …
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scholarly articleQ13442814

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P819ADS bibcode1997PNAS...94.3560M
P356DOI10.1073/PNAS.94.8.3560
P932PMC publication ID20478
P698PubMed publication ID9108015
P5875ResearchGate publication ID14109815

P50authorMing-Jer TsaiQ90840739
P2093author name stringH Mutoh
A B Leiter
F J Naya
B P Fung
J Nishitani
P2860cites workA new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteinsQ24299387
Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequenceQ24300878
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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivoQ28298865
Firefly luciferase gene: structure and expression in mammalian cellsQ29616519
The MyoD family and myogenesis: redundancy, networks, and thresholdsQ29618503
Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix proteinQ29618504
Two Related Helix-Loop-Helix Proteins Participate in Separate Cell-Specific Complexes That Bind the Insulin EnhancerQ33263393
MyoD family: a paradigm for development?Q34271215
HLH proteins, fly neurogenesis, and vertebrate myogenesisQ34345733
CAP and RNA polymerase interactions with thelacpromoter: binding stoichiometry and long range effectsQ35669029
A single element of the elastase I enhancer is sufficient to direct transcription selectively to the pancreas and gut.Q36648587
Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factorQ36706855
Identification of a transcriptional enhancer important for enteroendocrine and pancreatic islet cell-specific expression of the secretin geneQ36821670
Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteinsQ36961228
Expression of the trans-active factors that stimulate insulin control element-mediated activity appear to precede insulin gene transcription.Q38311840
Subunit structure of cell-specific E box-binding proteins analyzed by quantitation of electrophoretic mobility shift.Q38326835
On the origin of pancreatic endocrine cellsQ39636911
The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexesQ40678585
Cell-specific and ubiquitous factors are responsible for the enhancer activity of the rat insulin II geneQ41665716
Novel insulin promoter- and enhancer-binding proteins that discriminate between pancreatic alpha- and beta-cellsQ41676218
B-cell- and myocyte-specific E2-box-binding factors contain E12/E47-like subunitsQ41697036
Single-step purification of bacterially expressed polypeptides containing an oligo-histidine domain.Q54683892
Peptide YY expression is an early event in colonic endocrine cell differentiation: evidence from normal and transgenic miceQ61852939
Studies in Transgenic Mice Reveal Potential Relationships between Secretin-producing Cells and Other Endocrine Cell TypesQ61852945
Expression of peptide YY in all four islet cell types in the developing mouse pancreas suggests a common peptide YY-producing progenitorQ72345108
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)3560-3564
P577publication date1997-04-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleThe basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression
P478volume94