| scholarly article | Q13442814 |
| P356 | DOI | 10.1210/MEND-5-2-292 |
| P953 | full work available at URL | http://academic.oup.com/mend/article-pdf/5/2/292/9079119/mend0292.pdf |
| P698 | PubMed publication ID | 1710033 |
| P2093 | author name string | C. Nelson | |
| W. J. Rutter | |||
| M. S. German | |||
| L. G. Moss | |||
| M. A. Blanar | |||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | endocrinology | Q162606 |
| preproinsulin | Q7240673 | ||
| enhancer | Q913367 | ||
| P304 | page(s) | 292-299 | |
| P577 | publication date | 1991-02-01 | |
| P1433 | published in | Molecular Endocrinology | Q3319475 |
| P1476 | title | Two related helix-loop-helix proteins participate in separate cell-specific complexes that bind the insulin enhancer | |
| Two Related Helix-Loop-Helix Proteins Participate in Separate Cell-Specific Complexes That Bind the Insulin Enhancer | |||
| P478 | volume | 5 |
| Q36700487 | A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines |
| Q36313656 | A novel glucose-responsive element in the human insulin gene functions uniquely in primary cultured islets |
| Q40602787 | Acetylation of the BETA2 transcription factor by p300-associated factor is important in insulin gene expression |
| Q40018593 | An activation domain of the helix-loop-helix transcription factor E2A shows cell type preference in vivo in microinjected zebra fish embryos |
| Q72080055 | An endocrine-specific element is an integral component of an exocrine-specific pancreatic enhancer |
| Q72771036 | Analysis of an insulin gene transcription control element. Positive and negative regulation appears to be mediated by different element sequences |
| Q28145110 | Autoregulation and maturity onset diabetes of the young transcription factors control the human PAX4 promoter |
| Q36557143 | BETA3, a novel helix-loop-helix protein, can act as a negative regulator of BETA2 and MyoD-responsive genes |
| Q38354309 | Basic helix-loop-helix protein MyoD displays modest DNA binding specificity |
| Q40406248 | Cell-specific expression of helix-loop-helix transcription factors encoded by the E2A gene. |
| Q36678585 | Cell-specific helix-loop-helix factor required for pituitary expression of the pro-opiomelanocortin gene |
| Q34114554 | Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein. |
| Q24315615 | Cloning and characterization of a basic helix-loop-helix protein expressed in early mesoderm and the developing somites |
| Q24314353 | Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice |
| Q32048256 | Differential regulation of the glucagon and insulin I gene promoters by the basic helix-loop-helix transcription factors E47 and BETA2. |
| Q40505363 | Distribution and characterization of helix-loop-helix enhancer-binding proteins from pancreatic beta cells and lymphocytes |
| Q36694428 | E1A-mediated inhibition of myogenesis correlates with a direct physical interaction of E1A12S and basic helix-loop-helix proteins |
| Q36827022 | E2A expression, nuclear localization, and in vivo formation of DNA- and non-DNA-binding species during B-cell development |
| Q24644579 | Functional analysis of the nuclear LIM domain interactor NLI |
| Q36569313 | Functional characterization of the transactivation properties of the PDX-1 homeodomain protein |
| Q48724454 | Functional characterization of the trout insulin promoter: implications for fish as a favorable model of pancreas development |
| Q28566461 | Glucose induced MAPK signalling influences NeuroD1-mediated activation and nuclear localization |
| Q38303384 | Glucose modulates the binding activity of the beta-cell transcription factor IUF1 in a phosphorylation-dependent manner |
| Q36268104 | Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters |
| Q36645030 | Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression |
| Q22254644 | HASH-1 and E2-2 are expressed in human neuroblastoma cells and form a functional complex |
| Q24554353 | Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms |
| Q31171099 | Hepatocyte nuclear factor 1 alpha is expressed in a hamster insulinoma line and transactivates the rat insulin I gene |
| Q22254691 | Human homologue of maid: A dominant inhibitory helix-loop-helix protein associated with liver-specific gene expression |
| Q41315831 | Hxt encodes a basic helix-loop-helix transcription factor that regulates trophoblast cell development |
| Q36821670 | Identification of a transcriptional enhancer important for enteroendocrine and pancreatic islet cell-specific expression of the secretin gene |
| Q37382028 | Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1 |
| Q24540063 | Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47. |
| Q38362801 | Insulin upstream factor 1 and a novel ubiquitous factor bind to the human islet amyloid polypeptide/amylin gene promoter |
| Q47773645 | Islet expression of Rhombotin and Isl-1 suggests cell type specific exposure of LIM-domain epitopes |
| Q28115311 | Isolation and characterization of a novel transcription factor that binds to and activates insulin control element-mediated expression |
| Q28510639 | Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells |
| Q34160557 | Meso1, a basic-helix-loop-helix protein involved in mammalian presomitic mesoderm development |
| Q39502371 | MicroRNA-19b downregulates insulin 1 through targeting transcription factor NeuroD1. |
| Q38314105 | Modified binding of proteins from calcitonin-negative tumor cells to the neuroendocrine-specific CANNTG motif of the calcitonin gene |
| Q36693552 | Molecular characterization of the rat insulin enhancer-binding complex 3b2. Cloning of a binding factor with putative helicase motifs |
| Q24540685 | Novel transcriptional potentiation of BETA2/NeuroD on the secretin gene promoter by the DNA-binding protein Finb/RREB-1. |
| Q91891565 | Obesity-induced overexpression of miR-802 impairs insulin transcription and secretion |
| Q39452906 | Overlapping expression of early B-cell factor and basic helix-loop-helix proteins as a mechanism to dictate B-lineage-specific activity of the lambda5 promoter |
| Q36655139 | Pan/E2A expression precedes immunoglobulin heavy-chain expression during B lymphopoiesis in nontransformed cells, and Pan/E2A proteins are not detected in myeloid cells |
| Q35967171 | Pancreatic beta cells express a diverse set of homeobox genes |
| Q28752551 | Pancreatic beta cells require NeuroD to achieve and maintain functional maturity |
| Q46629073 | Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors. |
| Q31009822 | Pur-1, a zinc-finger protein that binds to purine-rich sequences, transactivates an insulin promoter in heterologous cells |
| Q40793174 | Regulation of G1 progression by E2A and Id helix-loop-helix proteins |
| Q40392325 | Regulation of insulin gene expression by overlapping DNA-binding elements. |
| Q37603286 | Regulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes |
| Q33901612 | Review article: transcriptional events controlling the terminal differentiation of intestinal endocrine cells |
| Q39723264 | Single chain dimers of MASH-1 bind DNA with enhanced affinity |
| Q36507951 | The E2A gene product contains two separable and functionally distinct transcription activation domains |
| Q33957229 | The NeuroD1/BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein binding |
| Q40890059 | The RIPE3b1 activator of the insulin gene is composed of a protein(s) of approximately 43 kDa, whose DNA binding activity is inhibited by protein phosphatase treatment. |
| Q57316015 | The agouti-related protein and body fatness in humans |
| Q36102024 | The basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression |
| Q40079354 | The basic helix-loop-helix transcription factor NeuroD1 facilitates interaction of Sp1 with the secretin gene enhancer |
| Q39450757 | The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter |
| Q41295233 | The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site. |
| Q40678585 | The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes |
| Q42501381 | The insulin gene contains multiple transcriptional elements that respond to glucose |
| Q40722406 | The mif gene is transcriptionally regulated by glucose in insulin-secreting cells |
| Q38322223 | The nuclear localization signal (NLS) of PDX-1 is part of the homeodomain and represents a novel type of NLS. |
| Q37238174 | Thermodynamic and structural determinants of differential Pdx1 binding to elements from the insulin and IAPP promoters |
| Q52196199 | Tissue-specific and developmental regulation of the rat insulin II gene enhancer, RIPE3, in transgenic mice. |
| Q40850468 | Transcription factors recognizing overlapping C1-A2 binding sites positively regulate insulin gene expression |
| Q40569624 | Transcription of the insulin gene: towards defining the glucose-sensitive cis-element and trans-acting factors |
| Q24646171 | Transcriptional synergy between LIM-homeodomain proteins and basic helix-loop-helix proteins: the LIM2 domain determines specificity |
| Q36029808 | Transfection and overexpression of the calcium binding protein calbindin-D28k results in a stimulatory effect on insulin synthesis in a rat beta cell line (RIN 1046-38) |
| Q36549834 | c-jun inhibits insulin control element-mediated transcription by affecting the transactivation potential of the E2A gene products |
| Q36644212 | c-jun inhibits transcriptional activation by the insulin enhancer, and the insulin control element is the target of control |
| Q33786590 | p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene |
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