scholarly article | Q13442814 |
P2093 | author name string | R Stein | |
A Sharma | |||
E Henderson | |||
C V Wright | |||
M Peshavaria | |||
P2860 | cites work | Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif | Q24305878 |
Sequence of the cDNA encoding ITF-1, a positive-acting transcription factor | Q24633686 | ||
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase | Q26778389 | ||
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors | Q27860552 | ||
Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells | Q27860599 | ||
Isolation and characterization of a novel transcription factor that binds to and activates insulin control element-mediated expression | Q28115311 | ||
Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme | Q28275910 | ||
The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice | Q28513142 | ||
The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain | Q28574370 | ||
Firefly luciferase gene: structure and expression in mammalian cells | Q29616519 | ||
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum | Q29618151 | ||
Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein | Q29618504 | ||
The insulin gene promoter. A simplified nomenclature | Q48789347 | ||
Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny. | Q51128200 | ||
Autonomous endodermal determination in Xenopus: regulation of expression of the pancreatic gene XlHbox 8. | Q52206427 | ||
Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons. | Q52251957 | ||
The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein. | Q52541323 | ||
Ultrastructural studies of the ontogeny of fetal human and porcine endocrine pancreas, with special reference to colocalization of the four major islet hormones | Q67521588 | ||
Insulin cells of pancreas extend neurites but do not arise from the neuroectoderm | Q67677100 | ||
A rapid, sensitive, and inexpensive assay for chloramphenicol acetyltransferase | Q68760342 | ||
Structure and evolution of the insulin gene | Q69924638 | ||
XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor | Q72740560 | ||
Insulin-promoter-factor 1 is required for pancreas development in mice | Q29619695 | ||
Transcription activation by the adenovirus E1a protein | Q29620538 | ||
Two Related Helix-Loop-Helix Proteins Participate in Separate Cell-Specific Complexes That Bind the Insulin Enhancer | Q33263393 | ||
An inhibitory domain of E12 transcription factor prevents DNA binding in E12 homodimers but not in E12 heterodimers | Q33332420 | ||
Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene | Q33679093 | ||
Reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression | Q33886988 | ||
Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells | Q34290753 | ||
A mutational analysis of the insulin gene transcription control region: expression in beta cells is dependent on two related sequences within the enhancer | Q34375782 | ||
Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor | Q34407862 | ||
Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes | Q35856801 | ||
Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters | Q36268104 | ||
The E2A gene product contains two separable and functionally distinct transcription activation domains | Q36507951 | ||
The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells | Q36556697 | ||
Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression | Q36645030 | ||
A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cells | Q36660430 | ||
Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor | Q36706855 | ||
Two distinct class A helix-loop-helix transcription factors, E2A and BETA1, form separate DNA binding complexes on the insulin gene E box. | Q36723820 | ||
Identification of a pancreatic beta-cell insulin gene transcription factor that binds to and appears to activate cell-type-specific expression: its possible relationship to other cellular factors that bind to a common insulin gene sequence | Q36755529 | ||
Pancreatic beta-cell-type-specific expression of the rat insulin II gene is controlled by positive and negative cellular transcriptional elements | Q36758591 | ||
Mutagenesis of the rat insulin II 5'-flanking region defines sequences important for expression in HIT cells | Q36764691 | ||
Analysis of E1A-mediated growth regulation functions: binding of the 300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activity | Q36783092 | ||
Onset of cell-specific gene expression in the developing mouse pancreas | Q36822712 | ||
Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins | Q36961228 | ||
Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1 | Q37382028 | ||
IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene | Q37629612 | ||
Glucose modulates the binding activity of the beta-cell transcription factor IUF1 in a phosphorylation-dependent manner | Q38303384 | ||
Expression of the trans-active factors that stimulate insulin control element-mediated activity appear to precede insulin gene transcription. | Q38311840 | ||
Insulin upstream factor 1 and a novel ubiquitous factor bind to the human islet amyloid polypeptide/amylin gene promoter | Q38362801 | ||
Distribution and characterization of helix-loop-helix enhancer-binding proteins from pancreatic beta cells and lymphocytes | Q40505363 | ||
The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes | Q40678585 | ||
IPF1, a homeodomain-containing transactivator of the insulin gene | Q40874284 | ||
The Neural Crest and the Origin of the Insulin-Producing and Other Gastrointestinal Hormone-Producing Cells | Q41067572 | ||
The human glucokinase gene beta-cell-type promoter: an essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells | Q41156786 | ||
The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site. | Q41295233 | ||
Cell-specific and ubiquitous factors are responsible for the enhancer activity of the rat insulin II gene | Q41665716 | ||
The midgestational human fetal pancreas contains cells coexpressing islet hormones | Q42453451 | ||
Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation | Q42808711 | ||
Ultrastructural studies of early morphogenesis and cytodifferentiation in the embryonic mammalian pancreas | Q45228648 | ||
Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1. | Q46446650 | ||
extradenticle raises the DNA binding specificity of homeotic selector gene products | Q46446845 | ||
Characterization of the two nonallelic genes encoding mouse preproinsulin | Q48370767 | ||
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 3987-3996 | |
P577 | publication date | 1997-07-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Functional characterization of the transactivation properties of the PDX-1 homeodomain protein | |
P478 | volume | 17 |
Q30441221 | A feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis |
Q40602787 | Acetylation of the BETA2 transcription factor by p300-associated factor is important in insulin gene expression |
Q40218659 | Amino acid 1-209 is essential for PDX-1-mediated repression of human CMV IE promoter activity |
Q40478891 | Cell-specific cytotoxicity of human pancreatic adenocarcinoma cells using rat insulin promoter thymidine kinase-directed gene therapy. |
Q28591464 | DNA binding and transcriptional activation by a PDX1.PBX1b.MEIS2b trimer and cooperation with a pancreas-specific basic helix-loop-helix complex |
Q24562726 | Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus |
Q40239436 | Development of a novel beta-cell specific promoter system for the identification of insulin-producing cells in in vitro cell cultures |
Q37497514 | Effects of a novel curcumin derivative on insulin synthesis and secretion in streptozotocin-treated rat pancreatic islets in vitro. |
Q40675167 | Experimental conversion of liver to pancreas |
Q24631284 | Gli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal disease |
Q37237607 | Gli-similar proteins: their mechanisms of action, physiological functions, and roles in disease. |
Q28566461 | Glucose induced MAPK signalling influences NeuroD1-mediated activation and nuclear localization |
Q41014247 | Glucose stimulates the activation domain potential of the PDX-1 homeodomain transcription factor |
Q24297588 | ISL1 physically interacts with BETA2 to promote insulin gene transcriptional synergy in non-beta cells |
Q24567626 | Identification of PCIF1, a POZ domain protein that inhibits PDX-1 (MODY4) transcriptional activity |
Q39449324 | Identification of a portable repression domain and an E1A-responsive activation domain in Pax4: a possible role of Pax4 as a transcriptional repressor in the pancreas |
Q40657679 | Induction of Mad expression leads to augmentation of insulin gene transcription |
Q24540063 | Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47. |
Q24563557 | Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes |
Q42594814 | Novel pattern of AtXlox gene expression in starfish Archaster typicus embryos |
Q38359562 | Overexpression of the Pdx-1 homeodomain transcription factor impairs glucose metabolism in cultured rat hepatocytes. |
Q36951907 | PDX-1 interaction and regulation of the Pancreatic Derived Factor (PANDER, FAM3B) promoter |
Q38887124 | PRMT1 promotes glucose toxicity-induced β cell dysfunction by regulating the nucleo-cytoplasmic trafficking of PDX-1 in a FOXO1-dependent manner in INS-1 cells |
Q47888790 | Pancreatic beta cell-specific transcription of the pdx-1 gene. The role of conserved upstream control regions and their hepatic nuclear factor 3beta sites |
Q28566577 | Pax6 and Pdx1 form a functional complex on the rat somatostatin gene upstream enhancer |
Q28573262 | Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation |
Q34967266 | Regulation of gene promoters of hypothalamic peptides |
Q33963287 | Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3. |
Q40429175 | Relative contribution of PDX-1, MafA and E47/beta2 to the regulation of the human insulin promoter |
Q44744692 | Specific gene expression and therapy for pancreatic cancer using the cytosine deaminase gene directed by the rat insulin promoter |
Q33964485 | Specific protein-protein interaction between basic helix-loop-helix transcription factors and homeoproteins of the Pitx family |
Q42856791 | Suppression of the pancreatic duodenal homeodomain transcription factor-1 (Pdx-1) promoter by sterol regulatory element-binding protein-1c (SREBP-1c). |
Q40811956 | The DNA binding activity of the RIPE3b1 transcription factor of insulin appears to be influenced by tyrosine phosphorylation |
Q28507859 | The Krüppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcription |
Q33957229 | The NeuroD1/BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein binding |
Q33680353 | The Pancreatic and Duodenal Homeobox Protein PDX-1 Regulates the Ductal Specific Keratin 19 through the Degradation of MEIS1 and DNA Binding |
Q39450757 | The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter |
Q38322223 | The nuclear localization signal (NLS) of PDX-1 is part of the homeodomain and represents a novel type of NLS. |
Q28609099 | Transcription factors direct the development and function of pancreatic beta cells |
Q40850468 | Transcription factors recognizing overlapping C1-A2 binding sites positively regulate insulin gene expression |
Q35185531 | Transcriptomic analysis of the lesser spotted catshark (Scyliorhinus canicula) pancreas, liver and brain reveals molecular level conservation of vertebrate pancreas function. |
Q33786590 | p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene |
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