p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene

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p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.18.5.2957
P932PMC publication ID110675
P698PubMed publication ID9566915

P50authorYi QiuQ96230228
P2093author name stringR Stein
Y Qiu
A Sharma
P2860cites workSynergistic activation of transcription by CBP and p53Q24311979
Binding and modulation of p53 by p300/CBP coactivatorsQ24312018
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient miceQ24314353
Phosphorylation of CREB at Ser-133 induces complex formation with CREB-binding protein via a direct mechanismQ24315753
Nuclear protein CBP is a coactivator for the transcription factor CREBQ24319801
A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1AQ24336667
Human p300 protein is a coactivator for the transcription factor MyoDQ24336865
Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2CQ24647260
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domainQ27860534
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptorsQ27860552
The transcriptional coactivators p300 and CBP are histone acetyltransferasesQ27860843
IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin geneQ37629612
Glucose modulates the binding activity of the beta-cell transcription factor IUF1 in a phosphorylation-dependent mannerQ38303384
Adenovirus E1A downregulates cJun- and JunB-mediated transcription by targeting their coactivator p300Q40019548
Distribution and characterization of helix-loop-helix enhancer-binding proteins from pancreatic beta cells and lymphocytesQ40505363
The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexesQ40678585
CBP-induced stimulation of c-Fos activity is abrogated by E1A.Q40789535
IPF1, a homeodomain-containing transactivator of the insulin geneQ40874284
Analysis of the role of E2A-encoded proteins in insulin gene transcriptionQ41084277
p300 and CBP as transcriptional regulators and targets of oncogenic events.Q41263784
The reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to high glucose concentration is associated with the loss of RIPE3b1 and STF-1 transcription factor expressionQ41307369
The beta cell transcription factors and development of the pancreasQ41496269
Cell-specific and ubiquitous factors are responsible for the enhancer activity of the rat insulin II geneQ41665716
The insulin gene contains multiple transcriptional elements that respond to glucoseQ42501381
p300, and p300-associated proteins, are components of TATA-binding protein (TBP) complexes.Q42512156
Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiationQ42808711
Cell-specific expression of the rat insulin gene: evidence for role of two distinct 5' flanking elementsQ43524876
The p300/CBP family: integrating signals with transcription factors and chromatinQ45155861
Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1.Q46446650
The insulin gene promoter. A simplified nomenclatureQ48789347
Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny.Q51128200
Tissue-specific and developmental regulation of the rat insulin II gene enhancer, RIPE3, in transgenic mice.Q52196199
Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitroQ57888777
A family of transcriptional adaptor proteins targeted by the E1A oncoproteinQ59070933
Adenoviral ElA-associated protein p300 as a functional homologue of the transcriptional co-activator CBPQ59095054
CBP as a transcriptional coactivator of c-MybQ64382929
A rapid, sensitive, and inexpensive assay for chloramphenicol acetyltransferaseQ68760342
XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factorQ72740560
Regulation of insulin gene transcriptionQ81067684
The CBP co-activator is a histone acetyltransferaseQ28131758
Phosphorylated CREB binds specifically to the nuclear protein CBPQ28265019
Differential roles of p300 and PCAF acetyltransferases in muscle differentiationQ28276083
Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptorQ28286827
Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300Q28301874
The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomainQ28574370
Firefly luciferase gene: structure and expression in mammalian cellsQ29616519
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenumQ29618151
Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix proteinQ29618504
Insulin-promoter-factor 1 is required for pancreas development in miceQ29619695
Transcription activation by the adenovirus E1a proteinQ29620538
Two Related Helix-Loop-Helix Proteins Participate in Separate Cell-Specific Complexes That Bind the Insulin EnhancerQ33263393
Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cellsQ34290753
A mutational analysis of the insulin gene transcription control region: expression in beta cells is dependent on two related sequences within the enhancerQ34375782
Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxesQ35856801
Characterization of monoclonal antibodies raised against p300: both p300 and CBP are present in intracellular TBP complexesQ35877660
The basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expressionQ36102024
Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promotersQ36268104
c-jun inhibits insulin control element-mediated transcription by affecting the transactivation potential of the E2A gene productsQ36549834
The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cellsQ36556697
The adenovirus E1A repression domain disrupts the interaction between the TATA binding protein and the TATA box in a manner reversible by TFIIB.Q36567742
Functional characterization of the transactivation properties of the PDX-1 homeodomain proteinQ36569313
c-jun inhibits transcriptional activation by the insulin enhancer, and the insulin control element is the target of controlQ36644212
Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expressionQ36645030
A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cellsQ36660430
Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factorQ36706855
Two distinct class A helix-loop-helix transcription factors, E2A and BETA1, form separate DNA binding complexes on the insulin gene E box.Q36723820
Cooperativity of sequence elements mediates tissue specificity of the rat insulin II geneQ36756394
Pancreatic beta-cell-type-specific expression of the rat insulin II gene is controlled by positive and negative cellular transcriptional elementsQ36758591
Insulin gene enhancer activity is inhibited by adenovirus 5 E1a gene productsQ36762817
Mutagenesis of the rat insulin II 5'-flanking region defines sequences important for expression in HIT cellsQ36764691
Analysis of E1A-mediated growth regulation functions: binding of the 300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activityQ36783092
Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteinsQ36961228
The nuclear hormone receptor coactivator SRC-1 is a specific target of p300.Q37287938
CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcriptionQ37376082
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectpreproinsulinQ7240673
P304page(s)2957-2964
P577publication date1998-05-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titlep300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene
P478volume18

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cites work (P2860)
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