| scholarly article | Q13442814 |
| P50 | author | Roger J. Colbran | Q43077467 |
| P2093 | author name string | R Stein | |
| L Zhao | |||
| E Henderson | |||
| M A Cissell | |||
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| Firefly luciferase gene: structure and expression in mammalian cells | Q29616519 | ||
| Regulation of transcription by MAP kinase cascades | Q29618477 | ||
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| Two Related Helix-Loop-Helix Proteins Participate in Separate Cell-Specific Complexes That Bind the Insulin Enhancer | Q33263393 | ||
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| A mutational analysis of the insulin gene transcription control region: expression in beta cells is dependent on two related sequences within the enhancer | Q34375782 | ||
| The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene transcription by high glucose in pancreatic beta-cells | Q34434997 | ||
| Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes | Q35856801 | ||
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| The regulation of transcription by phosphorylation | Q36377421 | ||
| Hepatic nuclear factor 3- and hormone-regulated expression of the phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein 1 genes | Q36550128 | ||
| Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression | Q36645030 | ||
| Molecular characterization of the rat insulin enhancer-binding complex 3b2. Cloning of a binding factor with putative helicase motifs | Q36693552 | ||
| Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor | Q36706855 | ||
| Identification of a pancreatic beta-cell insulin gene transcription factor that binds to and appears to activate cell-type-specific expression: its possible relationship to other cellular factors that bind to a common insulin gene sequence | Q36755529 | ||
| Mutagenesis of the rat insulin II 5'-flanking region defines sequences important for expression in HIT cells | Q36764691 | ||
| Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins | Q36961228 | ||
| Chronic exposure of betaTC-6 cells to supraphysiologic concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator | Q37352067 | ||
| Glucose modulates the binding activity of the beta-cell transcription factor IUF1 in a phosphorylation-dependent manner | Q38303384 | ||
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| Glucose stimulates translocation of the homeodomain transcription factor PDX1 from the cytoplasm to the nucleus in pancreatic beta-cells | Q40984605 | ||
| Glucose stimulates the activation domain potential of the PDX-1 homeodomain transcription factor | Q41014247 | ||
| The role of the insulin control element and RIPE3b1 activators in glucose-stimulated transcription of the insulin gene | Q41275508 | ||
| The reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to high glucose concentration is associated with the loss of RIPE3b1 and STF-1 transcription factor expression | Q41307369 | ||
| The beta cell transcription factors and development of the pancreas | Q41496269 | ||
| Maximal serum stimulation of the c-fos serum response element requires both the serum response factor and a novel binding factor, SRE-binding protein | Q41602043 | ||
| The insulin gene contains multiple transcriptional elements that respond to glucose | Q42501381 | ||
| Cell-specific expression of the rat insulin gene: evidence for role of two distinct 5' flanking elements | Q43524876 | ||
| Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development | Q44055107 | ||
| Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells | Q56592281 | ||
| Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas | Q59070691 | ||
| A rapid, sensitive, and inexpensive assay for chloramphenicol acetyltransferase | Q68760342 | ||
| Structure and evolution of the insulin gene | Q69924638 | ||
| Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells | Q73224788 | ||
| Early-onset type-II diabetes mellitus (MODY4) linked to IPF1 | Q73777239 | ||
| Impaired beta-cell functions induced by chronic exposure of cultured human pancreatic islets to high glucose | Q77795060 | ||
| Regulation of insulin gene transcription | Q81067684 | ||
| Function of the human insulin promoter in primary cultured islet cells | Q95817497 | ||
| P433 | issue | 14 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | preproinsulin | Q7240673 |
| P304 | page(s) | 10532-10537 | |
| P577 | publication date | 2000-04-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | The RIPE3b1 activator of the insulin gene is composed of a protein(s) of approximately 43 kDa, whose DNA binding activity is inhibited by protein phosphatase treatment | |
| P478 | volume | 275 |
| Q43283307 | A Comprehensive Survey of the Roles of Highly Disordered Proteins in Type 2 Diabetes. |
| Q24537502 | Conserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6 |
| Q40660400 | Glucose regulates insulin gene transcription by hyperacetylation of histone h4. |
| Q37832964 | Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus |
| Q42830601 | Identification of a novel PDX-1 binding site in the human insulin gene enhancer |
| Q24531243 | Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA. |
| Q37052883 | Inactivation of specific β cell transcription factors in type 2 diabetes |
| Q24540063 | Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47. |
| Q40376352 | Interactions between areas I and II direct pdx-1 expression specifically to islet cell types of the mature and developing pancreas |
| Q37896334 | MafA and MafB activity in pancreatic β cells |
| Q39975757 | MafA and MafB regulate Pdx1 transcription through the Area II control region in pancreatic beta cells |
| Q37209534 | MafA is a dedicated activator of the insulin gene in vivo |
| Q24309331 | MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene |
| Q28510639 | Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells |
| Q24676036 | Nuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in {beta}-cells |
| Q33800071 | Phosphorylation within the MafA N terminus regulates C-terminal dimerization and DNA binding |
| Q33930262 | Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes |
| Q40392325 | Regulation of insulin gene expression by overlapping DNA-binding elements. |
| Q37603286 | Regulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes |
| Q40811956 | The DNA binding activity of the RIPE3b1 transcription factor of insulin appears to be influenced by tyrosine phosphorylation |
| Q24626092 | The MafA transcription factor appears to be responsible for tissue-specific expression of insulin |
| Q42805946 | The islet beta cell-enriched RIPE3b1/Maf transcription factor regulates pdx-1 expression |
| Q43213325 | The stability and transactivation potential of the mammalian MafA transcription factor are regulated by serine 65 phosphorylation |
| Q44212502 | Transcription factor occupancy of the insulin gene in vivo. Evidence for direct regulation by Nkx2.2. |
| Q40850468 | Transcription factors recognizing overlapping C1-A2 binding sites positively regulate insulin gene expression |
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