The Mutational Robustness of Influenza A Virus

scientific article

The Mutational Robustness of Influenza A Virus is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1371/JOURNAL.PPAT.1005856
P932PMC publication ID5003363
P698PubMed publication ID27571422

P50authorAdam S. LauringQ56869110
Elisa VisherQ92550253
William FitzsimmonsQ96249405
Shawn E WhitefieldQ42187758
P2093author name stringJohn T McCrone
P2860cites workStability-mediated epistasis constrains the evolution of an influenza proteinQ21128791
Ultrafast and memory-efficient alignment of short DNA sequences to the human genomeQ21183894
Evolution of mutational robustness in an RNA virusQ21563619
Distribution of fitness effects caused by single-nucleotide substitutions in bacteriophage f1Q22065129
Distribution of Fitness and Virulence Effects Caused by Single-Nucleotide Substitutions in Tobacco Etch VirusQ22065440
Mutational fitness effects in RNA and single-stranded DNA viruses: common patterns revealed by site-directed mutagenesis studiesQ22065913
The distribution of fitness effects caused by single-nucleotide substitutions in an RNA virusQ22066390
Fitness and its role in evolutionary geneticsQ22122004
The distribution of fitness effects of new mutationsQ22122013
Distribution of fitness effects caused by random insertion mutations in Escherichia coliQ22122455
Comparison of the mutation rates of human influenza A and B virusesQ24542982
RNA virus error catastrophe: direct molecular test by using ribavirinQ24599371
Viral mutation ratesQ24611162
Evolution and ecology of influenza A virusesQ24634698
The genomic and epidemiological dynamics of human influenza A virusQ24649077
Mechanisms of genetic robustness in RNA virusesQ27472944
Negative effects of chemical mutagenesis on the adaptive behavior of vesicular stomatitis virusQ27480816
Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza VirusQ27660330
Site-directed mutagenesis by overlap extension using the polymerase chain reactionQ27860503
Large-scale sequencing of human influenza reveals the dynamic nature of viral genome evolutionQ28275712
The fitness effects of random mutations in single-stranded DNA and RNA bacteriophagesQ28471969
Reliable detection of subclonal single-nucleotide variants in tumour cell populations.Q51372620
The evolution of epidemic influenza.Q53579716
Pacing a small cage: mutation and RNA virusesQ56384384
The fitness effects of synonymous mutations in DNA and RNA virusesQ56895857
Universal primer set for the full-length amplification of all influenza A virusesQ57202943
Does mutational robustness inhibit extinction by lethal mutagenesis in viral populations?Q28474346
Prevalence of epistasis in the evolution of influenza A surface proteinsQ28477179
Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeuticsQ28535361
A quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivityQ28537708
Extremely High Mutation Rate of HIV-1 In VivoQ28548089
A DNA transfection system for generation of influenza A virus from eight plasmidsQ29642855
A synchronized global sweep of the internal genes of modern avian influenza virus.Q30358996
Intrahost dynamics of influenza virus reassortmentQ30361454
High-throughput profiling of influenza A virus hemagglutinin gene at single-nucleotide resolutionQ30362478
Single-reaction genomic amplification accelerates sequencing and vaccine production for classical and Swine origin human influenza a viruses.Q30378960
The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian hostQ30418377
Genetic drift of HIV populations in cultureQ33419841
Epistatically interacting substitutions are enriched during adaptive protein evolutionQ33583647
Rapid fitness losses in mammalian RNA virus clones due to Muller's ratchetQ33612467
An experimentally determined evolutionary model dramatically improves phylogenetic fit.Q33923545
The inherent mutational tolerance and antigenic evolvability of influenza hemagglutininQ33943327
Mutational and fitness landscapes of an RNA virus revealed through population sequencingQ33953331
Redundancy, antiredundancy, and the robustness of genomesQ34009559
Permissive secondary mutations enable the evolution of influenza oseltamivir resistanceQ34118992
Why do RNA viruses recombine?Q34197204
Perspective: Evolution and detection of genetic robustnessQ34271971
Epochal evolution shapes the phylodynamics of interpandemic influenza A (H3N2) in humansQ34593954
Influenza virus reassortment occurs with high frequency in the absence of segment mismatchQ34778503
Evolution of mutational robustnessQ35040941
Codon bias and frequency-dependent selection on the hemagglutinin epitopes of influenza A virusQ35163216
Mutational robustness of an RNA virus influences sensitivity to lethal mutagenesisQ35826103
Global circulation patterns of seasonal influenza viruses vary with antigenic driftQ35844377
Measurements of Intrahost Viral Diversity Are Extremely Sensitive to Systematic Errors in Variant CallingQ36021962
The effects of a deleterious mutation load on patterns of influenza A/H3N2's antigenic evolution in humansQ36177833
Site-Specific Amino Acid Preferences Are Mostly Conserved in Two Closely Related Protein HomologsQ36226944
Adaptive value of high mutation rates of RNA viruses: separating causes from consequencesQ36248500
Exploitation of nucleic acid packaging signals to generate a novel influenza virus-based vector stably expressing two foreign genesQ36525136
An overlapping protein-coding region in influenza A virus segment 3 modulates the host responseQ36554219
Robustness promotes evolvability of thermotolerance in an RNA virusQ36843864
Measurement of the mutation rates of animal viruses: influenza A virus and poliovirus type 1.Q36864763
Accurate Measurement of the Effects of All Amino-Acid Mutations on Influenza HemagglutininQ37049959
Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteinsQ37395095
RNA virus genetic robustness: possible causes and some consequencesQ38028045
The role of mutational robustness in RNA virus evolutionQ38092577
Effective lethal mutagenesis of influenza virus by three nucleoside analogsQ38919847
Congruent evolution of fitness and genetic robustness in vesicular stomatitis virusQ39194772
Codon usage determines the mutational robustness, evolutionary capacity, and virulence of an RNA virusQ39243651
Modeling viral genome fitness evolution associated with serial bottleneck events: evidence of stationary states of fitnessQ39684439
Genetic bottlenecks and population passages cause profound fitness differences in RNA viruses.Q40043495
Influenza Virus Reassortment Is Enhanced by Semi-infectious Particles but Can Be Suppressed by Defective Interfering Particles.Q40462345
RNA Recombination Enhances Adaptability and Is Required for Virus Spread and VirulenceQ40492307
Expected Effect of Deleterious Mutations on Within-Host Adaptation of PathogensQ41140967
Theory of lethal mutagenesis for virusesQ41979840
Point mutation rate of bacteriophage PhiX174.Q41982885
A genetic background with low mutational robustness is associated with increased adaptability to a novel host in an RNA virusQ45381935
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P921main subjectinfluenza A virusQ834390
P304page(s)e1005856
P577publication date2016-08-29
P1433published inPLOS PathogensQ283209
P1476titleThe Mutational Robustness of Influenza A Virus
P478volume12

Reverse relations

cites work (P2860)
Q94683610A Review of Current Interventions for COVID-19 Prevention
Q57459851A novel framework for inferring parameters of transmission from viral sequence data
Q38734385A novel twelve class fluctuation test reveals higher than expected mutation rates for influenza A viruses
Q57000842A speed-fidelity trade-off determines the mutation rate and virulence of an RNA virus
Q98386709Adaptation of turnip mosaic potyvirus to a specific niche reduces its genetic and environmental robustness
Q59351031Causes and Consequences of Spatial Within-Host Viral Spread
Q92376654Computational Approaches and Challenges to Developing Universal Influenza Vaccines
Q83230283Coupling adaptive molecular evolution to phylodynamics using fitness-dependent birth-death models
Q90282522Deep Mutational Scan of the Highly Conserved Influenza A Virus M1 Matrix Protein Reveals Substantial Intrinsic Mutational Tolerance
Q58089569Determining the Mutation Bias of Favipiravir in Influenza Using Next-generation Sequencing
Q66679163Effects of Arbovirus Multi-Host Life Cycles on Dinucleotide and Codon Usage Patterns
Q59353300Effects of Transmission Bottlenecks on the Diversity of Influenza A Virus
Q52655516Emergency Services of Viral RNAs: Repair and Remodeling.
Q38621087Epistatic Interactions within the Influenza A Virus Polymerase Complex Mediate Mutagen Resistance and Replication Fidelity
Q47613574Evidence for the Selective Basis of Transition-to-Transversion Substitution Bias in Two RNA Viruses
Q30401640Immune Escape Variants of H9N2 Influenza Viruses Containing Deletions at the Hemagglutinin Receptor Binding Site Retain Fitness In Vivo and Display Enhanced Zoonotic Characteristics
Q47551825Influenza A virus hemagglutinin glycosylation compensates for antibody escape fitness costs.
Q90241717Influenza Hemagglutinin and Neuraminidase: Yin⁻Yang Proteins Coevolving to Thwart Immunity
Q64112031Mutagenesis Scanning Uncovers Evolutionary Constraints on Tobacco Etch Potyvirus Membrane-Associated 6K2 Protein
Q56985102Mutation and Epistasis in Influenza Virus Evolution
Q64099779Mutational load causes stochastic evolutionary outcomes in acute RNA viral infection
Q47159566On the effective depth of viral sequence data
Q93263114Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections
Q40064406Population Diversity and Collective Interactions during Influenza Virus Infection
Q46655978Proofreading-Deficient Coronaviruses Adapt for Increased Fitness over Long-Term Passage without Reversion of Exoribonuclease-Inactivating Mutations.
Q92730130Quantifying within-host diversity of H5N1 influenza viruses in humans and poultry in Cambodia
Q55251922Quantitative characterization of all single amino acid variants of a viral capsid-based drug delivery vehicle.
Q47158568Selection on non-antigenic gene segments of seasonal influenza A virus and its impact on adaptive evolution
Q36298674Strain-dependent mutational effects for Pepino mosaic virus in a natural host.
Q54222557The complexities of viral mutation rates.
Q40225361The not-so-infinite malleability of RNA viruses: Viral and cellular determinants of RNA virus mutation rates.
Q52347585Viral fitness correlates with the magnitude and direction of the perturbation induced in the host's transcriptome: the tobacco etch potyvirus - tobacco case study.

Search more.