The role of CD8+ T-cell replicative senescence in human aging

scientific article

The role of CD8+ T-cell replicative senescence in human aging is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1111/J.0105-2896.2005.00259.X
P698PubMed publication ID15882351
P5875ResearchGate publication ID7859488

P2093author name stringJanice Man
Rita B Effros
Mirabelle Dagarag
Carolyn Spaulding
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Osteoprotegerin ligand: a regulator of immune responses and bone physiology.Q34079327
Differential regulation of CD8+ T cell senescence in mice and men.Q34133538
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Cellular senescence, cancer and aging: the telomere connectionQ34416433
CD8+CD28- T suppressor cells and the induction of antigen-specific, antigen-presenting cell-mediated suppression of Th reactivityQ34448485
CD8+CD28- T cells: certainties and uncertainties of a prevalent human T-cell subsetQ34546418
Differential impairment of lytic and cytokine functions in senescent human immunodeficiency virus type 1-specific cytotoxic T lymphocytesQ34758044
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Oxidative stress and aging: beyond correlationQ35185561
Replicative senescence: the final stage of memory T cell differentiation?Q35713374
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Is immunosenescence infectious?Q35846370
Alloreactive cloned T cell lines. I. Interactions between cloned amplifier and cytolytic T cell linesQ36343465
Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy".Q36362764
Regulated expression of telomerase activity in human T lymphocyte development and activationQ36366852
Divergent telomerase and CD28 expression patterns in human CD4 and CD8 T cells following repeated encounters with the same antigenic stimulusQ40683550
Evolution and plasticity of CTL responses against HIV.Q41103084
Cellular aging (the Hayflick limit) and species longevity: a unification model based on clonal successionQ41458650
Replicative senescence of T cells: does the Hayflick Limit lead to immune exhaustion?Q41591692
Resistance to apoptosis in human CD8+ T cells that reach replicative senescence after multiple rounds of antigen-specific proliferationQ41697585
Replicative senescence in the immune system: impact of the Hayflick limit on T-cell function in the elderlyQ41739819
Dual function of a human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte clone: inhibition of HIV replication by noncytolytic mechanisms and lysis of HIV-infected CD4+ cellsQ42644082
Long term culture of tumour-specific cytotoxic T cellsQ42799119
Identification of the T cell clones expanding within both CD8(+)CD28(+) and CD8(+)CD28(-) T cell subsets in recipients of allogeneic hematopoietic cell grafts and its implication in post-transplant skewing of T cell receptor repertoireQ43613026
Mechanism of telomerase induction during T cell activationQ44208409
Large clonal expansions of human virus-specific memory cytotoxic T lymphocytes within the CD57+ CD28- CD8+ T-cell populationQ44933069
Decreased perforin and granzyme B expression in senescent HIV-1-specific cytotoxic T lymphocytesQ45231483
CD28-negative CD8-positive cytotoxic T lymphocytes mediate hepatocellular damage in hepatitis C virus infectionQ45663282
Alveolar CD8+CD57+ lymphocytes in human immunodeficiency virus infection produce an inhibitor of cytotoxic functionsQ45789958
CD28 expression in T cell aging and human longevityQ48005206
The 1983 Robert W. Kleemeier Award lecture. The destiny of cells: mechanisms and implications of senescenceQ48411731
Rapid turnover of the CD8(+)CD28(-) T-cell subset of effector cells in the circulation of patients with head and neck cancer.Q52007016
Differentiation of human CD8 T cells: implications for in vivo persistence of CD8+ CD28- cytotoxic effector clones.Q52035114
A phenotypic study of CD8+ lymphocyte subsets in infants using three-color flow cytometry.Q52058346
The in vitro senescence of human T lymphocytes: failure to divide is not associated with a loss of cytolytic activity or memory T cell phenotype.Q52065587
T cell cultures and the Hayflick limit.Q53554989
Long-term growth and cloning of non-transformed lymphocytes.Q53568762
Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNAQ56930699
Large numbers of dysfunctional CD8+ T lymphocytes bearing receptors for a single dominant CMV epitope in the very oldQ56986889
Relación de las subpoblaciones de linfocitos T con los marcadores pronósticos de la infección pediátrica por el virus de la inmunodeficiencia humanaQ57080084
CD8+CD45RA+CD27-CD28-T-cell subset in PBL of cervical cancer patients representing CD8+T-cells being able to recognize cervical cancer associated antigens provided by HPV 16 E7Q57209293
Comparison of CD8+ T-cell subsets in HIV-infected rapid progressor children versus non–rapid progressor childrenQ57996484
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γQ59064307
P304page(s)147-157
P577publication date2005-06-01
P1433published inImmunological ReviewsQ15724582
P1476titleThe role of CD8+ T-cell replicative senescence in human aging
P478volume205

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