review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Janice Man | |
Rita B Effros | |||
Mirabelle Dagarag | |||
Carolyn Spaulding | |||
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Bone versus immune system | Q28140389 | ||
Population biology of lymphocytes: the flight for survival | Q28145640 | ||
Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells | Q28215003 | ||
The serial cultivation of human diploid cell strains | Q29547356 | ||
Telomeres shorten during ageing of human fibroblasts | Q29547357 | ||
Association between telomere length in blood and mortality in people aged 60 years or older | Q29615532 | ||
Aging and oxidative stress | Q33339881 | ||
Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals | Q33870216 | ||
Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging | Q33946993 | ||
Induction of hTERT expression and telomerase activity by estrogens in human ovary epithelium cells | Q33963529 | ||
Osteoprotegerin ligand: a regulator of immune responses and bone physiology. | Q34079327 | ||
Differential regulation of CD8+ T cell senescence in mice and men. | Q34133538 | ||
From cells to organisms: can we learn about aging from cells in culture? | Q34214183 | ||
Cellular senescence, cancer and aging: the telomere connection | Q34416433 | ||
CD8+CD28- T suppressor cells and the induction of antigen-specific, antigen-presenting cell-mediated suppression of Th reactivity | Q34448485 | ||
CD8+CD28- T cells: certainties and uncertainties of a prevalent human T-cell subset | Q34546418 | ||
Differential impairment of lytic and cytokine functions in senescent human immunodeficiency virus type 1-specific cytotoxic T lymphocytes | Q34758044 | ||
Premature ageing of the immune system: the cause of AIDS? | Q35016194 | ||
Oxidative stress and aging: beyond correlation | Q35185561 | ||
Replicative senescence: the final stage of memory T cell differentiation? | Q35713374 | ||
Engineering anticancer T cells for extended functional longevity | Q35832907 | ||
Is immunosenescence infectious? | Q35846370 | ||
Alloreactive cloned T cell lines. I. Interactions between cloned amplifier and cytolytic T cell lines | Q36343465 | ||
Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy". | Q36362764 | ||
Regulated expression of telomerase activity in human T lymphocyte development and activation | Q36366852 | ||
Divergent telomerase and CD28 expression patterns in human CD4 and CD8 T cells following repeated encounters with the same antigenic stimulus | Q40683550 | ||
Evolution and plasticity of CTL responses against HIV. | Q41103084 | ||
Cellular aging (the Hayflick limit) and species longevity: a unification model based on clonal succession | Q41458650 | ||
Replicative senescence of T cells: does the Hayflick Limit lead to immune exhaustion? | Q41591692 | ||
Resistance to apoptosis in human CD8+ T cells that reach replicative senescence after multiple rounds of antigen-specific proliferation | Q41697585 | ||
Replicative senescence in the immune system: impact of the Hayflick limit on T-cell function in the elderly | Q41739819 | ||
Dual function of a human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte clone: inhibition of HIV replication by noncytolytic mechanisms and lysis of HIV-infected CD4+ cells | Q42644082 | ||
Long term culture of tumour-specific cytotoxic T cells | Q42799119 | ||
Identification of the T cell clones expanding within both CD8(+)CD28(+) and CD8(+)CD28(-) T cell subsets in recipients of allogeneic hematopoietic cell grafts and its implication in post-transplant skewing of T cell receptor repertoire | Q43613026 | ||
Mechanism of telomerase induction during T cell activation | Q44208409 | ||
Large clonal expansions of human virus-specific memory cytotoxic T lymphocytes within the CD57+ CD28- CD8+ T-cell population | Q44933069 | ||
Decreased perforin and granzyme B expression in senescent HIV-1-specific cytotoxic T lymphocytes | Q45231483 | ||
CD28-negative CD8-positive cytotoxic T lymphocytes mediate hepatocellular damage in hepatitis C virus infection | Q45663282 | ||
Alveolar CD8+CD57+ lymphocytes in human immunodeficiency virus infection produce an inhibitor of cytotoxic functions | Q45789958 | ||
CD28 expression in T cell aging and human longevity | Q48005206 | ||
The 1983 Robert W. Kleemeier Award lecture. The destiny of cells: mechanisms and implications of senescence | Q48411731 | ||
Rapid turnover of the CD8(+)CD28(-) T-cell subset of effector cells in the circulation of patients with head and neck cancer. | Q52007016 | ||
Differentiation of human CD8 T cells: implications for in vivo persistence of CD8+ CD28- cytotoxic effector clones. | Q52035114 | ||
A phenotypic study of CD8+ lymphocyte subsets in infants using three-color flow cytometry. | Q52058346 | ||
The in vitro senescence of human T lymphocytes: failure to divide is not associated with a loss of cytolytic activity or memory T cell phenotype. | Q52065587 | ||
T cell cultures and the Hayflick limit. | Q53554989 | ||
Long-term growth and cloning of non-transformed lymphocytes. | Q53568762 | ||
Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA | Q56930699 | ||
Large numbers of dysfunctional CD8+ T lymphocytes bearing receptors for a single dominant CMV epitope in the very old | Q56986889 | ||
Relación de las subpoblaciones de linfocitos T con los marcadores pronósticos de la infección pediátrica por el virus de la inmunodeficiencia humana | Q57080084 | ||
CD8+CD45RA+CD27-CD28-T-cell subset in PBL of cervical cancer patients representing CD8+T-cells being able to recognize cervical cancer associated antigens provided by HPV 16 E7 | Q57209293 | ||
Comparison of CD8+ T-cell subsets in HIV-infected rapid progressor children versus non–rapid progressor children | Q57996484 | ||
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ | Q59064307 | ||
P304 | page(s) | 147-157 | |
P577 | publication date | 2005-06-01 | |
P1433 | published in | Immunological Reviews | Q15724582 |
P1476 | title | The role of CD8+ T-cell replicative senescence in human aging | |
P478 | volume | 205 |
Q52923047 | 2-Methoxyestradiol: A Hormonal Metabolite Modulates Stimulated T-Cells Function and proliferation. |
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Q90446908 | Accelerated immunosenescence in rheumatoid arthritis: impact on clinical progression |
Q37169526 | Adenosine deaminase modulation of telomerase activity and replicative senescence in human CD8 T lymphocytes |
Q45362853 | Adjuvants that stimulate TLR3 or NLPR3 pathways enhance the efficiency of influenza virus-like particle vaccines in aged mice. |
Q27004178 | Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes for metastatic melanoma: current status and future outlook |
Q44610015 | Age is an important determinant in humoral and T cell responses to immunization with hepatitis B surface antigen |
Q37077310 | Age-associated increase of low-avidity cytomegalovirus-specific CD8+ T cells that re-express CD45RA |
Q36751644 | Age-dependent alterations of the T cell repertoire and functional diversity of T cells of the aged |
Q30400174 | Age-related changes in memory and effector T cells responding to influenza A/H3N2 and pandemic A/H1N1 strains in humans |
Q28483967 | Age-related expansion of Tim-3 expressing T cells in vertically HIV-1 infected children |
Q35088160 | Aging and infectious diseases: workshop on HIV infection and aging: what is known and future research directions |
Q38191999 | Aging, nutrient signaling, hematopoietic senescence, and cancer |
Q64119330 | Alterations in bacterial communities, SCFA and biomarkers in an elderly HIV-positive and HIV-negative population in western Mexico |
Q45097081 | Are senescence and exhaustion intertwined or unrelated processes that compromise immunity? |
Q51012663 | Assessment of oxidative stress in lymphocytes with exercise. |
Q30417066 | Association between telomere length and experimentally induced upper respiratory viral infection in healthy adults |
Q24295841 | B7-H5 costimulates human T cells via CD28H |
Q33572405 | CD28(-) T cells: their role in the age-associated decline of immune function |
Q41190637 | CD4⁺CD28null T lymphocytes resemble CD8⁺CD28null T lymphocytes in their responses to IL-15 and IL-21 in HIV-infected patients |
Q64268788 | CD8 cytotoxic T cell responses to dominant tumor-associated antigens are profoundly weakened by aging yet subdominant responses retain functionality and expand in response to chemotherapy |
Q36185688 | CMV+ Serostatus Associates Negatively with CD4:CD8 Ratio Normalization in Controlled HIV-Infected Patients on cART. |
Q64101504 | COPD as a Disease of Immunosenescence |
Q38383224 | Cellular senescence: from growth arrest to immunogenic conversion |
Q41957098 | Challenges for vaccination in the elderly. |
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Q37564853 | Cytogenetic perspective of ageing and longevity in men and women |
Q36334037 | Cytokine profile and proviral load among Japanese immigrants and non-Japanese infected with HTLV-1 in a non-endemic area of Brazil |
Q40512629 | Cytomegalovirus serostatus, inflammation, and antibody response to influenza vaccination in older adults: The moderating effect of beta blockade. |
Q35774711 | Dendritic cells and aging: consequences for autoimmunity |
Q90601927 | Differential expression of immune markers in the patients with obstructive sleep apnea/hypopnea syndrome |
Q37351695 | Differentiation rather than aging of muscle stem cells abolishes their telomerase activity |
Q40074042 | Distinct aging profiles of CD8+ T cells in blood versus gastrointestinal mucosal compartments |
Q46172231 | Distinct gene signature revealed in white blood cells, CD4(+) and CD8(+) T cells in (NZBx NZW) F1 lupus mice after tolerization with anti-DNA Ig peptide |
Q37410488 | Dysregulation of CD8+ lymphocyte apoptosis, chronic disease, and immune regulation |
Q41869159 | Effect of ageing on CMV-specific CD8 T cells from CMV seropositive healthy donors |
Q26744527 | Effector, Memory, and Dysfunctional CD8(+) T Cell Fates in the Antitumor Immune Response |
Q37599553 | Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules. |
Q36322933 | Estrogen and telomerase in human peripheral blood mononuclear cells |
Q37354804 | First-line cART regimen impacts the course of CD8+ T-cell counts in HIV-infected patients that achieve sustained undetectable viral load |
Q33482103 | Functional unresponsiveness and replicative senescence of myeloid leukemia antigen-specific CD8+ T cells after allogeneic stem cell transplantation |
Q34150710 | HIV Infection, Inflammation, Immunosenescence, and Aging |
Q46042029 | HIV and Age Do Not Synergistically Affect Age-Related T cell Markers |
Q28730976 | Hepatitis B vaccine antibody response and the risk of clinical AIDS or death |
Q36221473 | High-Dose Nicotinamide Suppresses ROS Generation and Augments Population Expansion during CD8(+) T Cell Activation |
Q91788921 | How Does Obesity and Physical Activity Affect Aging?: Focused on Telomere as a Biomarker of Aging |
Q36220716 | Human regulatory T cells induce T-lymphocyte senescence |
Q44704847 | IL-15 preferentially enhances functional properties and antigen-specific responses of CD4+CD28(null) compared to CD4+CD28+ T cells |
Q40245420 | Immune System Dysfunction in the Elderly. |
Q34777989 | Immune aging and autoimmunity |
Q34036703 | Immune aging and rheumatoid arthritis |
Q92186275 | Immune response in LPD during methotrexate administration (MTX-LPD) in rheumatoid arthritis patients |
Q34079650 | Immune senescence in aged nonhuman primates |
Q38103191 | Immunosenescence and age-related viral diseases |
Q42270924 | Immunosenescence is associated with human cytomegalovirus and shortened telomeres in type I bipolar disorder. |
Q35854044 | Immunosenescence of the CD8(+) T cell compartment is associated with HIV-infection, but only weakly reflects age-related processes of adipose tissue, metabolism, and muscle in antiretroviral therapy-treated HIV-infected patients and controls |
Q36726822 | Immunosenescence: role and measurement in influenza vaccine response among the elderly |
Q39409318 | Immunosenescence: the Role of Aging in the Predisposition to Neuro-Infectious Complications Arising from the Treatment of Multiple Sclerosis |
Q64234120 | Immunosenescence: the potential role of myeloid-derived suppressor cells (MDSC) in age-related immune deficiency |
Q37301037 | Immunosenescence: what does it mean to health outcomes in older adults? |
Q83198645 | Impaired production of TNF-α by dendritic cells of older adults leads to a lower CD8+ T cell response against influenza |
Q37041389 | Inflammaging as a prodrome to Alzheimer's disease |
Q36225887 | Inflammaging decreases adaptive and innate immune responses in mice and humans |
Q36388062 | Inflammation markers predicting frailty and mortality in the elderly. |
Q38177684 | Inflammatory co-morbidities in HIV+ individuals: learning lessons from healthy ageing |
Q30422463 | Influenza vaccination in the face of immune exhaustion: is herd immunity effective for protecting the elderly? |
Q34705027 | Influenza vaccine responses in older adults |
Q31030019 | Influenza-specific T cells from older people are enriched in the late effector subset and their presence inversely correlates with vaccine response. |
Q35146532 | Interleukin-7 inhibits tumor-induced CD27-CD28- suppressor T cells: implications for cancer immunotherapy |
Q37500069 | KLRG1--more than a marker for T cell senescence |
Q33567625 | Kleemeier Award Lecture 2008--the canary in the coal mine: telomeres and human healthspan |
Q33755484 | Leukocyte function in the aging immune system |
Q54237859 | Levels of anti-CMV antibodies are modulated by the frequency and intensity of virus reactivations in kidney transplant patients. |
Q28393793 | Low social support is associated with shorter leukocyte telomere length in late life: multi-ethnic study of atherosclerosis |
Q36316521 | Lower GrB+ CD62Lhigh CD8 TCM effector lymphocyte response to influenza virus in older adults is associated with increased CD28null CD8 T lymphocytes |
Q35880403 | Mechanisms of immunosenescence: lessons from models of accelerated immune aging |
Q37408575 | Memory T cells need CD28 costimulation to remember |
Q46057511 | Metabolic reprogramming of human CD8+ memory T cells through loss of SIRT1. |
Q37172115 | Modulation of T lymphocyte replicative senescence via TNF-{alpha} inhibition: role of caspase-3. |
Q35201953 | Multifunctional cytomegalovirus (CMV)-specific CD8(+) T cells are not restricted by telomere-related senescence in young or old adults. |
Q35562281 | NKG2D expression in CD4+ T lymphocytes as a marker of senescence in the aged immune system. |
Q38460545 | Neuroendocrine and viral correlates of premature immunosenescence |
Q37510076 | Normal brain aging clinical, immunological, neuropsychological, and neuroimaging features. |
Q37137596 | Optimal window of caloric restriction onset limits its beneficial impact on T-cell senescence in primates |
Q36294809 | Persistence of tumor infiltrating lymphocytes in adoptive immunotherapy correlates with telomere length. |
Q51757878 | Polyomavirus-associated nephropathy risk in kidney transplants: the influence of recipient age and donor gender. |
Q34616800 | Predicting cytotoxic T-cell age from multivariate analysis of static and dynamic biomarkers |
Q36274133 | Preferential enhancement of older human T cell cytokine generation, chemotaxis, proliferation and survival by lenalidomide |
Q35107187 | Premature CD4+ T cell aging and its contribution to lymphopenia-induced proliferation of memory cells in autoimmune-prone non-obese diabetic mice |
Q37399302 | Premature aging of T cells is associated with faster HIV-1 disease progression |
Q34003932 | Principles of adoptive T cell cancer therapy |
Q33740540 | Prostaglandin E2 promotes features of replicative senescence in chronically activated human CD8+ T cells |
Q38071251 | Psychoneuroendocrine interventions aimed at attenuating immunosenescence: a review. |
Q28392217 | Race-Ethnicity, Poverty, Urban Stressors, and Telomere Length in a Detroit Community-based Sample |
Q36661010 | Reduced telomerase activity in human T lymphocytes exposed to cortisol |
Q35760179 | Reduced telomere length in rheumatoid arthritis is independent of disease activity and duration |
Q37235079 | Relationship between a frailty-related phenotype and progressive deterioration of the immune system in HIV-infected men. |
Q35493901 | Relationships of pulmonary function, inflammation, and T-cell activation and senescence in an HIV-infected cohort |
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Q44670813 | Reversal of functional defects in highly differentiated young and old CD8 T cells by PDL blockade |
Q35720116 | Role of CD8 T Cell Replicative Senescence in Human Aging and in HIV-mediated Immunosenescence |
Q37792338 | Role of CMV in immune senescence |
Q36610085 | Role of T lymphocyte replicative senescence in vaccine efficacy |
Q37470923 | Rudimentary signs of immunosenescence in Cytomegalovirus-seropositive healthy young adults |
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Q89969652 | Senescent T cells within suppressive tumor microenvironments: emerging target for tumor immunotherapy |
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Q35889270 | Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age. |
Q36884746 | Socioeconomic status, health behavior, and leukocyte telomere length in the National Health and Nutrition Examination Survey, 1999-2002. |
Q35141577 | Stress responsive biochemical anabolic/catabolic ratio and telomere length in older adults |
Q37780978 | Sustained CD28 expression delays multiple features of replicative senescence in human CD8 T lymphocytes |
Q43264753 | Systemic hypoxia promotes lymphocyte apoptosis induced by oxidative stress during moderate exercise |
Q50057803 | T Cell Dysfunction and Patient Age are Associated with Poor Outcomes after Mechanical Circulatory Support Device Implantation. |
Q27022690 | T cell replicative senescence in human aging |
Q36539888 | TLR agonists are highly effective at eliciting functional memory CTLs of effector memory phenotype in peptide immunization |
Q34880391 | TLR8 signaling enhances tumor immunity by preventing tumor-induced T-cell senescence |
Q39188424 | Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice. |
Q35880147 | Telomerase induction in T cells: a cure for aging and disease? |
Q35806766 | Telomere dysfunction, autoimmunity and aging. |
Q36782464 | Telomere length and mortality: a study of leukocytes in elderly Danish twins |
Q37952252 | Telomere length in cardiovascular disease: new challenges in measuring this marker of cardiovascular aging |
Q34137354 | Telomere/telomerase dynamics within the human immune system: Effect of chronic infection and stress |
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Q35110718 | Th1 response and systemic treg deficiency in inclusion body myositis. |
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