Osteoprotegerin ligand: a regulator of immune responses and bone physiology.

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Osteoprotegerin ligand: a regulator of immune responses and bone physiology. is …
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scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/S0167-5699(00)01718-7
P698PubMed publication ID11071528

P50authorJosef PenningerQ1674391
P2093author name stringY Y Kong
W J Boyle
P2860cites workTRANCE, a tumor necrosis factor family member, enhances the longevity and adjuvant properties of dendritic cells in vivoQ36375923
Immunotherapy with dendritic cells directed against tumor antigens shared with normal host cells results in severe autoimmune diseaseQ36375982
In vivo detection of dendritic cell antigen presentation to CD4(+) T cells.Q36377341
TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factorQ36380989
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolismQ37108966
Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerinQ39116155
The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts.Q41649459
A chimeric form of osteoprotegerin inhibits hypercalcemia and bone resorption induced by IL-1beta, TNF-alpha, PTH, PTHrP, and 1, 25(OH)2D3.Q41687961
Bone mineral density and bone metabolism in diabetes mellitusQ41710701
The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritisQ47569532
Lymph node genesis is induced by signaling through the lymphotoxin beta receptorQ47713223
The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissuesQ47713235
Selective disruption of lymphotoxin ligands reveals a novel set of mucosal lymph nodes and unique effects on lymph node cellular organization.Q52528591
Dendritic cells capable of stimulating T cells in germinal centresQ60085015
Role of lymphotoxin and the type I TNF receptor in the formation of germinal centersQ71095987
Mice deficient for the CD40 ligandQ72610555
Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cordQ73766127
Developing lymph nodes collect CD4+CD3- LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cellsQ73838320
Bone mineral density and bone turnover in asthmatics treated with long-term inhaled or oral glucocorticoidsQ77152862
Bone loss in autoimmune chronic active hepatitis on maintenance corticosteroid therapyQ93615302
Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type IIQ22010404
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
Osteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cellsQ24315251
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell functionQ24336057
RANK is essential for osteoclast and lymph node developmentQ24598872
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcificationQ24603266
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligandQ24653311
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKLQ24682139
Dendritic cells and the control of immunityQ27860918
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunityQ28138855
Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysisQ28141482
TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-SrcQ28142620
Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survivalQ28142897
RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesisQ28293009
Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxinQ28507630
The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formationQ28586300
Abnormal development of secondary lymphoid tissues in lymphotoxin beta-deficient miceQ28587099
Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient miceQ28587819
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligandQ29619331
Role of cytokines in rheumatoid arthritisQ29620713
Enhanced prostanoid release from monocytes of patients with rheumatoid arthritis and active systemic lupus erythematosusQ33555976
Selection of the T cell repertoire.Q33652536
Cell biology of the osteoclastQ33700885
Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2.Q33854381
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.Q34469691
Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptorQ36184139
TRANCE, a tumor necrosis factor family member critical for CD40 ligand-independent T helper cell activationQ36368029
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progressionQ36368539
Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cellsQ36375909
CD40-independent pathways of T cell help for priming of CD8(+) cytotoxic T lymphocytesQ36375919
P433issue10
P921main subjectphysiologyQ521
P304page(s)495-502
P577publication date2000-10-01
P1433published inTrends in ImmunologyQ15265730
P1476titleOsteoprotegerin ligand: a regulator of immune responses and bone physiology
P478volume21

Reverse relations

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