Overexpression of RalBP1 in colorectal cancer is an independent predictor of poor survival and early tumor relapse

scientific article

Overexpression of RalBP1 in colorectal cancer is an independent predictor of poor survival and early tumor relapse is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4161/CBT.20087
P932PMC publication ID3408974
P698PubMed publication ID22549157
P5875ResearchGate publication ID224878364

P50authorMarkus BüchlerQ89169
Jürgen WeitzQ65559730
Christoph ReissfelderQ86480797
Moritz KochQ90183187
Heike ElbersQ117232719
Nathan M MollbergQ117232722
Gunnar SteinertQ117232731
P2093author name stringFang-Ju Lin
Alexander Hamm
Maximillian Aigner
P2860cites workNovel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicinQ22254720
The epsin family of endocytic adaptors promotes fibrosarcoma migration and invasionQ24295295
Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activityQ24337472
Small G protein Ral and its downstream molecules regulate endocytosis of EGF and insulin receptorsQ24534185
Activation of the RalGEF/Ral pathway promotes prostate cancer metastasis to boneQ24681479
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
RLIP76, an effector of the GTPase Ral, interacts with the AP2 complex: involvement of the Ral pathway in receptor endocytosisQ28141762
Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76Q28182524
Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicityQ28182550
RLIP, an effector of the Ral GTPases, is a platform for Cdk1 to phosphorylate epsin during the switch off of endocytosis in mitosisQ28207629
RalB mobilizes the exocyst to drive cell migrationQ28570438
RalBP1 is necessary for metastasis of human cancer cell linesQ30433862
RalA and RalB: antagonistic relatives in cancer cell migrationQ30437796
RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migrationQ30444197
RALA and RALBP1 regulate mitochondrial fission at mitosisQ30503960
Epsin binds to the EH domain of POB1 and regulates receptor-mediated endocytosisQ33292368
Signal pathways which promote invasion and metastasis: critical and distinct contributions of extracellular signal-regulated kinase and Ral-specific guanine exchange factor pathwaysQ33969356
Adenosine triphosphate-dependent transport of doxorubicin, daunomycin, and vinblastine in human tissues by a mechanism distinct from the P-glycoproteinQ34130602
Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells.Q34592093
Rlip76 transports sunitinib and sorafenib and mediates drug resistance in kidney cancerQ34729940
mTOR-independent translational control of the extrinsic cell death pathway by RalA.Q35131738
Transport of glutathione conjugates and chemotherapeutic drugs by RLIP76 (RALBP1): a novel link between G-protein and tyrosine kinase signaling and drug resistanceQ35179100
Ral-GTPases: approaching their 15 minutes of fameQ35187818
Ral GTPases: corrupting the exocyst in cancer cellsQ36161656
Ral: mediator of membrane traffickingQ36510072
Regression of melanoma in a murine model by RLIP76 depletionQ38315672
The small G-protein RalA stimulates metastasis of transformed cells.Q38335738
Increased expression of cdc2 inhibits transport function of RLIP76 and promotes apoptosisQ39859514
Activation of RalA is critical for Ras-induced tumorigenesis of human cells.Q40410788
RLIP76 transports vinorelbine and mediates drug resistance in non-small cell lung cancer.Q40459619
Accelerated metabolism and exclusion of 4-hydroxynonenal through induction of RLIP76 and hGST5.8 is an early adaptive response of cells to heat and oxidative stressQ43720112
RLIP76 is a major determinant of radiation sensitivityQ46604639
Regression of lung and colon cancer xenografts by depleting or inhibiting RLIP76 (Ral-binding protein 1)Q80274383
P433issue8
P921main subjectcolorectal cancerQ188874
colorectal carcinomaQ25493920
overexpressionQ61643320
P304page(s)694-700
P577publication date2012-06-01
P1433published inCancer Biology and TherapyQ2544651
P1476titleOverexpression of RalBP1 in colorectal cancer is an independent predictor of poor survival and early tumor relapse
P478volume13

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cites work (P2860)
Q92124212CS-PEI/Beclin-siRNA Downregulate Multidrug Resistance Proteins and Increase Paclitaxel Therapeutic Efficacy against NSCLC
Q36563027Complexity of molecular alterations impacts pancreatic cancer prognosis.
Q39415229Endocytic adaptor protein epsin is elevated in prostate cancer and required for cancer progression
Q42051924P300 regulates the human RLIP76 promoter activity and gene expression
Q39225715RLIP76 Inhibition: A Promising Developmental Therapy for Neuroblastoma
Q37741408RLIP76 Targeted Therapy for Kidney Cancer
Q28294053Ral GTPases in tumorigenesis: emerging from the shadows

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