| scholarly article | Q13442814 |
| P50 | author | Atul Butte | Q4818772 |
| Sudhir Kumar | Q38053058 | ||
| P2093 | author name string | Rong Chen | |
| Li Liu | |||
| Joel T Dudley | |||
| Yuseob Kim | |||
| Glenn J Markov | |||
| Kristyn Gerold | |||
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| Evidence for positive selection and population structure at the human MAO-A gene | Q33894576 | ||
| Evidence of positive selection acting at the human dopamine receptor D4 gene locus | Q33897512 | ||
| Natural selection and population history in the human angiotensinogen gene (AGT): 736 complete AGT sequences in chromosomes from around the world. | Q33909877 | ||
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| Ranking insertion, deletion and nonsense mutations based on their effect on genetic information | Q33968927 | ||
| Evidence for hitchhiking of deleterious mutations within the human genome | Q34013656 | ||
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| A composite of multiple signals distinguishes causal variants in regions of positive selection | Q34091559 | ||
| Variation in transcription factor binding among humans | Q34105133 | ||
| Posttranslational modification of alpha-dystroglycan, the cellular receptor for arenaviruses, by the glycosyltransferase LARGE is critical for virus binding. | Q34123911 | ||
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| Coding single-nucleotide polymorphisms associated with complex vs. Mendelian disease: evolutionary evidence for differences in molecular effects. | Q37585393 | ||
| Spatial patterns of variation due to natural selection in humans | Q37613455 | ||
| Somatic gene mutation and human disease other than cancer: an update | Q37732916 | ||
| Uncovering the roles of rare variants in common disease through whole-genome sequencing | Q37755970 | ||
| Positive selection on MMP3 regulation has shaped heart disease risk | Q38337161 | ||
| Distinguishing cancer-associated missense mutations from common polymorphisms | Q38517012 | ||
| Positional conservation and amino acids shape the correct diagnosis and population frequencies of benign and damaging personal amino acid mutations | Q39968902 | ||
| Episodic evolution of pyrin in primates: human mutations recapitulate ancestral amino acid states | Q40606624 | ||
| Demography of longevity: past, present, and future trends | Q40735024 | ||
| Infant-parent co-sleeping in an evolutionary perspective: implications for understanding infant sleep development and the sudden infant death syndrome | Q40914144 | ||
| Germline fitness-based scoring of cancer mutations | Q41854090 | ||
| The Human Gene Mutation Database: providing a comprehensive central mutation database for molecular diagnostics and personalized genomics | Q42416347 | ||
| Estimating the rate of adaptive molecular evolution in the presence of slightly deleterious mutations and population size change | Q42624915 | ||
| Positive selection drives population differentiation in the skeletal genes in modern humans | Q43127347 | ||
| Understanding human disease mutations through the use of interspecific genetic variation | Q43572665 | ||
| Mechanisms and convergence of compensatory evolution in mammalian mitochondrial tRNAs | Q46163391 | ||
| The (non)malignancy of cancerous amino acidic substitutions | Q47588389 | ||
| Cancer-associated mutations are preferentially distributed in protein kinase functional sites | Q47589178 | ||
| MamMiBase: a mitochondrial genome database for mammalian phylogenetic studies | Q48150525 | ||
| A beta40 is a major form of beta-amyloid in nonhuman primates | Q48865847 | ||
| Large allele frequency differences between human continental groups are more likely to have occurred by drift during range expansions than by selection. | Q51673985 | ||
| Divergence and polymorphism under the nearly neutral theory of molecular evolution. | Q51868323 | ||
| Arginine residues at codons 112 and 158 in the apolipoprotein E gene correspond to the ancestral state in humans. | Q52846307 | ||
| Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants | Q57087763 | ||
| The Fate of Mutations Surfing on the Wave of a Range Expansion | Q57197882 | ||
| Medicine Needs Evolution | Q57267942 | ||
| Interpreting Results of Large-Scale Genetic Association Studies | Q57363065 | ||
| Deleterious mutations can surf to high densities on the wave front of an expanding population | Q80804846 | ||
| Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? | Q24685208 | ||
| The amino-acid mutational spectrum of human genetic disease | Q24793270 | ||
| A method and server for predicting damaging missense mutations | Q27860835 | ||
| Predicting the effects of amino acid substitutions on protein function | Q28250660 | ||
| The neutral theory of molecular evolution in the genomic era | Q28285816 | ||
| Thrifty genes for obesity, an attractive but flawed idea, and an alternative perspective: the 'drifty gene' hypothesis | Q28296794 | ||
| Evolutionary origins of the obesity epidemic: natural selection of thrifty genes or genetic drift following predation release? | Q28296804 | ||
| Analysis of genomic variation in non-coding elements using population-scale sequencing data from the 1000 Genomes Project | Q28740767 | ||
| TimeTree2: species divergence times on the iPhone | Q28742965 | ||
| Using bioinformatics to predict the functional impact of SNVs | Q28744088 | ||
| African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping | Q28748891 | ||
| Evolution in health and medicine Sackler colloquium: Evolution of the human lifespan and diseases of aging: roles of infection, inflammation, and nutrition | Q28752234 | ||
| Next generation tools for the annotation of human SNPs | Q28755491 | ||
| Natural selection on genes that underlie human disease susceptibility | Q28757653 | ||
| The evolution and population genetics of the ALDH2 locus: random genetic drift, selection, and low levels of recombination | Q29304892 | ||
| Integrating common and rare genetic variation in diverse human populations | Q29547220 | ||
| Human non-synonymous SNPs: server and survey | Q29547603 | ||
| Positive natural selection in the human lineage | Q29614585 | ||
| Haplotype diversity and linkage disequilibrium at human G6PD: recent origin of alleles that confer malarial resistance | Q29614684 | ||
| HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants | Q29614906 | ||
| Rare variants create synthetic genome-wide associations | Q29614955 | ||
| A systematic survey of loss-of-function variants in human protein-coding genes | Q29615756 | ||
| Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios | Q29616015 | ||
| Nonsense-mediated mRNA decay in health and disease | Q29619553 | ||
| Proportionally more deleterious genetic variation in European than in African populations. | Q30367885 | ||
| Single-molecule sequencing of an individual human genome | Q30434015 | ||
| Interrogating multiple aspects of variation in a full resequencing data set to infer human population size changes | Q31026014 | ||
| A practical genome scan for population-specific strong selective sweeps that have reached fixation | Q33278275 | ||
| Assessing the evolutionary impact of amino acid mutations in the human genome | Q33339383 | ||
| Worldwide population differentiation at disease-associated SNPs | Q33340690 | ||
| MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in disease | Q33503932 | ||
| Sequence and structure signatures of cancer mutation hotspots in protein kinases | Q33510934 | ||
| Similarly strong purifying selection acts on human disease genes of all evolutionary ages | Q33633483 | ||
| Non-synonymous and synonymous coding SNPs show similar likelihood and effect size of human disease association | Q33735944 | ||
| Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes | Q33736558 | ||
| Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations? | Q33799136 | ||
| Evolution in health and medicine Sackler colloquium: Genetic architecture of a complex trait and its implications for fitness and genome-wide association studies | Q33844411 | ||
| Classic selective sweeps were rare in recent human evolution | Q34165349 | ||
| Demographic history and rare allele sharing among human populations | Q34197613 | ||
| Phylomedicine: an evolutionary telescope to explore and diagnose the universe of disease mutations | Q34201078 | ||
| Evolutionary meta-analysis of association studies reveals ancient constraints affecting disease marker discovery | Q34258585 | ||
| A method for detecting recent selection in the human genome from allele age estimates | Q34264356 | ||
| Disentangling the effects of demography and selection in human history | Q34346838 | ||
| Dobzhansky-Muller incompatibilities in protein evolution | Q34380180 | ||
| Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens. | Q34449464 | ||
| Colloquium paper: human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency | Q34505486 | ||
| The incidentalome: a threat to genomic medicine | Q34546699 | ||
| Joint effects of genetic hitchhiking and background selection on neutral variation | Q34609915 | ||
| Nucleotide variability at G6pd and the signature of malarial selection in humans. | Q34616522 | ||
| How reliable are empirical genomic scans for selective sweeps? | Q34655368 | ||
| Improving the assessment of the outcome of nonsynonymous SNVs with a consensus deleteriousness score, Condel. | Q34768428 | ||
| A genome-wide comparison of the functional properties of rare and common genetic variants in humans | Q34768431 | ||
| Evolution of a malaria resistance gene in wild primates | Q34988839 | ||
| A polygenic basis for late-onset disease | Q35053431 | ||
| Single-nucleotide evolutionary constraint scores highlight disease-causing mutations | Q35132701 | ||
| Evolutionary anatomies of positions and types of disease-associated and neutral amino acid mutations in the human genome | Q35225651 | ||
| Haplotype analysis of hemochromatosis: evaluation of different linkage-disequilibrium approaches and evolution of disease chromosomes | Q35250515 | ||
| Coalescence-time distributions in a serial founder model of human evolutionary history | Q35297676 | ||
| Rare and common variants: twenty arguments | Q35533255 | ||
| An enhanced MITOMAP with a global mtDNA mutational phylogeny | Q35608504 | ||
| Recent human effective population size estimated from linkage disequilibrium | Q35698958 | ||
| Most rare missense alleles are deleterious in humans: implications for complex disease and association studies | Q35752568 | ||
| The functional spectrum of low-frequency coding variation | Q35840674 | ||
| Nonsense-mediated decay approaches the clinic | Q35851264 | ||
| Living with the past: evolution, development, and patterns of disease | Q35890929 | ||
| Clan genomics and the complex architecture of human disease | Q36851578 | ||
| Darwinian and demographic forces affecting human protein coding genes | Q37176315 | ||
| 20 years of human mtDNA pathologic point mutations: carefully reading the pathogenicity criteria | Q37288948 | ||
| Genome-wide association studies: potential next steps on a genetic journey | Q37292893 | ||
| Decanalization and the origin of complex disease | Q37361140 | ||
| P433 | issue | 8 | |
| P304 | page(s) | 1383-1394 | |
| P577 | publication date | 2012-06-04 | |
| P1433 | published in | Genome Research | Q5533485 |
| P1476 | title | Human genomic disease variants: a neutral evolutionary explanation | |
| P478 | volume | 22 |
| Q37229420 | A Molecular Evolutionary Reference for the Human Variome |
| Q28681899 | A phylomedicine approach to understanding the evolution of auditory sensory perception and disease in mammals |
| Q46262002 | Atlas of human diseases influenced by genetic variants with extreme allele frequency differences |
| Q30370239 | Conformational dynamics of nonsynonymous variants at protein interfaces reveals disease association. |
| Q36279051 | De novo mutational profile in RB1 clarified using a mutation rate modeling algorithm |
| Q37433965 | Disease consequences of human adaptation. |
| Q39051665 | Evolution-informed modeling improves outcome prediction for cancers |
| Q37261995 | Excess of Deleterious Mutations around HLA Genes Reveals Evolutionary Cost of Balancing Selection. |
| Q38673851 | Integration of structural dynamics and molecular evolution via protein interaction networks: a new era in genomic medicine |
| Q28602218 | Linking Genes to Cardiovascular Diseases: Gene Action and Gene-Environment Interactions |
| Q26745243 | Molecular Signatures of Natural Selection for Polymorphic Genes of the Human Dopaminergic and Serotonergic Systems: A Review |
| Q88454830 | Neutral Theory, Disease Mutations, and Personal Exomes |
| Q35619329 | PaPI: pseudo amino acid composition to score human protein-coding variants. |
| Q33614650 | Properties of human disease genes and the role of genes linked to Mendelian disorders in complex disease aetiology |
| Q90356949 | Somatic selection distinguishes oncogenes and tumor suppressor genes |
| Q49613390 | The origin of human complex diversity: Stochastic epistatic modules and the intrinsic compatibility between distributional robustness and phenotypic changeability |
| Q28067740 | Understanding rare and common diseases in the context of human evolution |
| Q36243590 | Using Disease-Associated Coding Sequence Variation to Investigate Functional Compensation by Human Paralogous Proteins |
| Q36170334 | e-GRASP: an integrated evolutionary and GRASP resource for exploring disease associations |
| Q58712240 | γ2 GABAR Trafficking and the Consequences of Human Genetic Variation |
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