| scholarly article | Q13442814 |
| P356 | DOI | 10.1093/MOLBEV/MSW127 |
| P8608 | Fatcat ID | release_z22erquo5vcejec7rdp2msdvhm |
| P932 | PMC publication ID | 5026253 |
| P698 | PubMed publication ID | 27436009 |
| P50 | author | Daniel M. Jordan | Q42406427 |
| Tobias L. Lenz | Q42424850 | ||
| P2093 | author name string | Shamil R Sunyaev | |
| Victor Spirin | |||
| P2860 | cites work | Fundamental concepts in genetics: Effective population size and patterns of molecular evolution and variation | Q22122006 |
| The effect of deleterious mutations on neutral molecular variation | Q24532876 | ||
| Genetic drift in an infinite population. The pseudohitchhiking model | Q24548113 | ||
| Hitchhiking under positive Darwinian selection | Q24548125 | ||
| The NHGRI GWAS Catalog, a curated resource of SNP-trait associations | Q24568334 | ||
| DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome | Q24644436 | ||
| Scan of human genome reveals no new Loci under ancient balancing selection | Q24676642 | ||
| Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity | Q24684291 | ||
| The genetics of inbreeding depression | Q26810001 | ||
| A method and server for predicting damaging missense mutations | Q27860835 | ||
| The hitch-hiking effect of a favourable gene | Q28241578 | ||
| Divergence time and population size in the lineage leading to modern humans | Q28284222 | ||
| Systematic localization of common disease-associated variation in regulatory DNA | Q29614895 | ||
| Natural selection on protein-coding genes in the human genome | Q29615352 | ||
| The genetic association database | Q29617244 | ||
| A model-based approach for identifying signatures of ancient balancing selection in genetic data | Q30000667 | ||
| Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases | Q30278872 | ||
| Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency | Q30427957 | ||
| Footprints of ancient-balanced polymorphisms in genetic variation data from closely related species | Q30870290 | ||
| Balancing selection and its effects on sequences in nearby genome regions | Q33242822 | ||
| Assessing the evolutionary impact of amino acid mutations in the human genome | Q33339383 | ||
| The coalescent process in models with selection | Q33954858 | ||
| The coalescent process in models with selection and recombination | Q33954863 | ||
| Genealogical structure among alleles regulating self-incompatibility in natural populations of flowering plants | Q33971279 | ||
| Evidence for hitchhiking of deleterious mutations within the human genome | Q34013656 | ||
| Towards a systems understanding of MHC class I and MHC class II antigen presentation. | Q34029353 | ||
| Current perspectives on the intensity of natural selection of MHC loci. | Q43165848 | ||
| Recombination and hitchhiking of deleterious alleles | Q43989379 | ||
| Long-Term Balancing Selection in LAD1 Maintains a Missense Trans-Species Polymorphism in Humans, Chimpanzees, and Bonobos | Q46784241 | ||
| Revising the human mutation rate: implications for understanding human evolution | Q47178250 | ||
| Large-scale sequence comparisons reveal unusually high levels of variation in the HLA-DQB1 locus in the class II region of the human MHC. | Q48024523 | ||
| How pathogens drive genetic diversity: MHC, mechanisms and misunderstandings. | Q51640195 | ||
| Heterozygote advantage fails to explain the high degree of polymorphism of the MHC. | Q52005186 | ||
| The Evolutionary Dynamics of Complex Polymorphisms | Q54294494 | ||
| Pathogen-Driven Selection and Worldwide HLA Class I Diversity | Q57008406 | ||
| Meiotic recombinations within major histocompatibility complex of human embryos | Q57783588 | ||
| A new theory of MHC evolution: beyond selection on the immune genes | Q60293904 | ||
| Sequence variability analysis of human class I and class II MHC molecules: functional and structural correlates of amino acid polymorphisms | Q73755061 | ||
| Diversifying and purifying selection in the peptide binding region of DRB in mammals | Q80890436 | ||
| A limited role for balancing selection | Q81339320 | ||
| Natural selection and the distribution of identity-by-descent in the human genome | Q34123495 | ||
| How selection shapes variation of the human major histocompatibility complex: a review | Q34287307 | ||
| Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs | Q34506401 | ||
| A method for estimating the intensity of overdominant selection from the distribution of allele frequencies | Q34611136 | ||
| Balancing selection on a regulatory region exhibiting ancient variation that predates human-neandertal divergence | Q34671949 | ||
| Balanced polymorphism selected by genetic versus infectious human disease | Q34762624 | ||
| Intensity of natural selection at the major histocompatibility complex loci. | Q35620658 | ||
| Obstruction of adaptation in diploids by recessive, strongly deleterious alleles | Q35644945 | ||
| Heterozygote advantage as a natural consequence of adaptation in diploids | Q35651257 | ||
| Most rare missense alleles are deleterious in humans: implications for complex disease and association studies | Q35752568 | ||
| Genome-wide patterns and properties of de novo mutations in humans | Q35798123 | ||
| Strong Selection at MHC in Mexicans since Admixture | Q35919633 | ||
| Gene map of the extended human MHC. | Q35968433 | ||
| Human genomic disease variants: a neutral evolutionary explanation | Q36130827 | ||
| Antagonistic versus nonantagonistic models of balancing selection: characterizing the relative timescales and hitchhiking effects of partial selective sweeps | Q36664255 | ||
| Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants | Q36913464 | ||
| Widespread balancing selection and pathogen-driven selection at blood group antigen genes | Q37119639 | ||
| Estimating the mutation load in human genomes | Q37121904 | ||
| Power of deep, all-exon resequencing for discovery of human trait genes | Q37129418 | ||
| A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. | Q37161006 | ||
| Pathogen selection drives nonoverlapping associations between HLA loci | Q37353186 | ||
| The sheltered genetic load linked to the s locus in plants: new insights from theoretical and empirical approaches in sporophytic self-incompatibility. | Q37424964 | ||
| Targets of balancing selection in the human genome | Q37434392 | ||
| The MHC, disease and selection | Q37832010 | ||
| Multiple instances of ancient balancing selection shared between humans and chimpanzees | Q39444727 | ||
| Cryptic MHC polymorphism revealed but not explained by selection on the class IIb peptide-binding region | Q39654550 | ||
| Computational prediction of MHC II-antigen binding supports divergent allele advantage and explains trans-species polymorphism. | Q39724653 | ||
| Complete MHC haplotype sequencing for common disease gene mapping | Q40510754 | ||
| The implications of intergenic polymorphism for major histocompatibility complex evolution | Q40851726 | ||
| HLA-H: a pseudogene with increased variation due to balancing selection at neighboring loci | Q40985729 | ||
| The effects of multilocus balancing selection on neutral variability. | Q42140870 | ||
| Genetic linkage and natural selection | Q42430166 | ||
| Sheltered load associated with S-alleles in Solanum carolinense | Q42618997 | ||
| P433 | issue | 10 | |
| P304 | page(s) | 2555-2564 | |
| P577 | publication date | 2016-06-28 | |
| P1433 | published in | Molecular Biology and Evolution | Q1992656 |
| P1476 | title | Excess of Deleterious Mutations around HLA Genes Reveals Evolutionary Cost of Balancing Selection | |
| P478 | volume | 33 |
| Q38688783 | A genomic perspective on HLA evolution |
| Q48131025 | Adaptive value of novel MHC immune gene variants |
| Q38642448 | Assembly and analysis of 100 full MHC haplotypes from the Danish population |
| Q38700594 | Cis-regulatory evolution in a wild primate: Infection-associated genetic variation drives differential expression of MHC-DQA1 in vitro. |
| Q103827045 | Deep whole-genome sequencing of multiple proband tissues and parental blood reveals the complex genetic etiology of congenital diaphragmatic hernias |
| Q46293897 | Detecting Long-Term Balancing Selection Using Allele Frequency Correlation |
| Q64079960 | Fine-Scale Characterization of Genomic Structural Variation in the Human Genome Reveals Adaptive and Biomedically Relevant Hotspots |
| Q39427560 | Introduction: MHC/KIR and governance of specificity |
| Q49830332 | Localization of adaptive variants in human genomes using averaged one-dependence estimation. |
| Q92947227 | Multiplicative fitness, rapid haplotype discovery, and fitness decay explain evolution of human MHC |
| Q92826296 | Novel Locus Associated with Symmetrical Lupoid Onychodystrophy in the Bearded Collie |
| Q64238457 | Pathogen diversity drives the evolution of generalist MHC-II alleles in human populations |
| Q57803784 | Revisiting the potential power of human leukocyte antigen (HLA) genes on relationship testing by massively parallel sequencing-based HLA typing in an extended family |
| Q94474376 | Targeted analysis of polymorphic loci from low-coverage shotgun sequence data allows accurate genotyping of HLA genes in historical human populations |
| Q47816520 | What has GWAS done for HLA and disease associations? |
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