Systems Analysis of Early Host Gene Expression Provides Clues for Transient Mycobacterium avium ssp avium vs. Persistent Mycobacterium avium ssp paratuberculosis Intestinal Infections

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Systems Analysis of Early Host Gene Expression Provides Clues for Transient Mycobacterium avium ssp avium vs. Persistent Mycobacterium avium ssp paratuberculosis Intestinal Infections is …
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scholarly articleQ13442814

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P819ADS bibcode2016PLoSO..1161946K
P356DOI10.1371/JOURNAL.PONE.0161946
P932PMC publication ID5031438
P698PubMed publication ID27653506

P2093author name stringHarris A Lewin
Robin E Everts
Carlos A Rossetti
Sara D Lawhon
Tamara Gull
Sangeeta Khare
Josely F Figueiredo
Kenneth L Drake
Jairo E S Nunes
Leslie Garry Adams
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Genomic homogeneity between Mycobacterium avium subsp. avium and Mycobacterium avium subsp. paratuberculosis belies their divergent growth ratesQ24801171
Correlative Gene Expression to Protective Seroconversion in Rift Valley Fever VaccinatesQ27330115
Differential cytokine gene expression profiles in the three pathological forms of sheep paratuberculosisQ33294117
CXCL10+ T cells and NK cells assist in the recruitment and activation of CXCR3+ and CXCL11+ leukocytes during Mycobacteria-enhanced colitisQ33340680
Activation of peroxisome proliferator-activated receptor gamma suppresses mast cell maturation involved in allergic diseases.Q33622220
Bovine NK cells can produce gamma interferon in response to the secreted mycobacterial proteins ESAT-6 and MPP14 but not in response to MPB70.Q34034026
Human biliary epithelial cell line Mz-ChA-1 expresses new isoforms of calmodulin-dependent protein kinase II.Q34295190
Systems biology analysis of gene expression during in vivo Mycobacterium avium paratuberculosis enteric colonization reveals role for immune toleranceQ34388671
FcεR1-mediated mast cell reactivity is amplified through prolonged Toll-like receptor-ligand treatmentQ34391700
Genome scale comparison of Mycobacterium avium subsp. paratuberculosis with Mycobacterium avium subsp. avium reveals potential diagnostic sequencesQ34455967
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Predicting the Role of IL-10 in the Regulation of the Adaptive Immune Responses in Mycobacterium avium Subsp. paratuberculosis Infections Using Mathematical ModelsQ35856002
Mycobacterium avium subsp. paratuberculosis and M. avium subsp. avium are independently evolved pathogenic clones of a much broader group of M. avium organismsQ36540489
Cytokine gene expression in peripheral blood mononuclear cells and tissues of cattle infected with Mycobacterium avium subsp. paratuberculosis: evidence for an inherent proinflammatory gene expression patternQ36575764
Rapid and sensitive detection of Mycobacterium avium subsp. paratuberculosis in bovine milk and feces by a combination of immunomagnetic bead separation-conventional PCR and real-time PCR.Q36597626
Lipids including cholesteryl linoleate and cholesteryl arachidonate contribute to the inherent antibacterial activity of human nasal fluidQ37002968
Development of a bovine ileal cannulation model to study the immune response and mechanisms of pathogenesis of paratuberculosisQ37156728
Analysis of the immune response to Mycobacterium avium subsp. paratuberculosis in experimentally infected calvesQ37623799
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Mucosal barrier, bacteria and inflammatory bowel disease: possibilities for therapyQ38223567
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Invited review: The economic impact and control of paratuberculosis in cattleQ38527691
Identification of early responsive genes in human amnion epithelial FL cells induced by N-methyl-N'-nitro-N-nitrosoguanidine using oligonucleotide microarray and quantitative real-time RT-PCR approachesQ39958859
Role of the Arf6 GDP/GTP cycle and Arf6 GTPase-activating proteins in actin remodeling and intracellular transportQ40306814
Mycobacterium avium subsp. paratuberculosis fibronectin attachment protein facilitates M-cell targeting and invasion through a fibronectin bridge with host integrinsQ40936221
Histopathological Characterization of Cutaneous Delayed-type Hypersensitivity and Correlations with Intestinal Pathology and Systemic Immune Responses in Sheep with Paratuberculosis.Q41113525
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Altered Toll-like receptor 9 signaling in Mycobacterium avium subsp. paratuberculosis-infected bovine monocytes reveals potential therapeutic targetsQ42288118
Toll-like receptor 2-dependent inhibition of macrophage class II MHC expression and antigen processing by 19-kDa lipoprotein of Mycobacterium tuberculosisQ43664763
Differential upregulation of chemokine receptors on CD56 NK cells and their transmigration to the site of infection in tuberculous pleurisy.Q43780656
Bovine monocyte TLR2 receptors differentially regulate the intracellular fate of Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. aviumQ43861987
ARHGAP10 is necessary for alpha-catenin recruitment at adherens junctions and for Listeria invasionQ44415217
Mitogen activated protein kinase p38 pathway is an important component of the anti-inflammatory response in Mycobacterium avium subsp. paratuberculosis-infected bovine monocytesQ44818484
Gene expression profiling of monocyte-derived macrophages following infection with Mycobacterium avium subspecies avium and Mycobacterium avium subspecies paratuberculosisQ45353311
Mycobacterium avium subspecies paratuberculosis and Mycobacterium avium subsp. avium infections in a tule elk (Cervus elaphus nannodes) herd.Q45950422
Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment.Q45986472
Nutrition-induced ketosis alters metabolic and signaling gene networks in liver of periparturient dairy cows.Q46958993
Gene expression and antimicrobial activity of bovine macrophages in response to Mycobacterium avium subsp. paratuberculosisQ47252881
Mycobacterium avium subspecies paratuberculosis suppresses expression of IL-12p40 and iNOS genes induced by signalling through CD40 in bovine monocyte-derived macrophages.Q54786735
TLR3-induced activation of mast cells modulates CD8+ T-cell recruitmentQ56984288
Early phase morphological lesions and transcriptional responses of bovine ileum infected with Mycobacterium avium subsp. paratuberculosisQ57129440
Role of the mitogen-activated protein kinase pathway in the differential response of bovine monocytes to Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. aviumQ79951560
Economic impact of reduced milk production associated with Johne's disease on dairy operations in the USAQ81348579
P275copyright licenseCreative Commons CC0 LicenseQ6938433
P6216copyright statuscopyrighted, dedicated to the public domain by copyright holderQ88088423
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectMycobacterium avium aviumQ310728
P304page(s)e0161946
P577publication date2016-09-21
P1433published inPLOS OneQ564954
P1476titleSystems Analysis of Early Host Gene Expression Provides Clues for Transient Mycobacterium avium ssp avium vs. Persistent Mycobacterium avium ssp paratuberculosis Intestinal Infections
P478volume11

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cites work (P2860)
Q93080919Application of Transcriptomics to Enhance Early Diagnostics of Mycobacterial Infections, with an Emphasis on Mycobacterium avium ssp. paratuberculosis
Q55403384Gene expression profiles of immune-regulatory genes in whole blood of cattle with a subclinical infection of Mycobacterium avium subsp. paratuberculosis.
Q46977882Pathogenesis, Molecular Genetics, and Genomics of Mycobacterium avium subsp. paratuberculosis, the Etiologic Agent of Johne's Disease.
Q40097780Systems Biology Analysis of Temporal In vivo Brucella melitensis and Bovine Transcriptomes Predicts host:Pathogen Protein-Protein Interactions

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