Alternative Splicing of Toll-Like Receptor 9 Transcript in Teleost Fish Grouper Is Regulated by NF-κB Signaling via Phosphorylation of the C-Terminal Domain of the RPB1 Subunit of RNA Polymerase II

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Alternative Splicing of Toll-Like Receptor 9 Transcript in Teleost Fish Grouper Is Regulated by NF-κB Signaling via Phosphorylation of the C-Terminal Domain of the RPB1 Subunit of RNA Polymerase II is …
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P819ADS bibcode2016PLoSO..1163415L
P356DOI10.1371/JOURNAL.PONE.0163415
P932PMC publication ID5033454
P698PubMed publication ID27658294

P2093author name stringTien-Hsien Chang
Cho-Fat Hui
Pinwen Peter Chiou
Frank Fang-Yao Lee
P2860cites workIRAK1b, a novel alternative splice variant of interleukin-1 receptor-associated kinase (IRAK), mediates interleukin-1 signaling and has prolonged stabilityQ24291311
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NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongationQ28141291
Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88Q28209138
Signal-dependent regulation of splicing via phosphorylation of Sam68Q28217232
Integrating mRNA processing with transcriptionQ28610124
RNA polymerase II C-terminal domain mediates regulation of alternative splicing by SRp20.Q40222409
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A slow RNA polymerase II affects alternative splicing in vivoQ40627617
Cutting edge: naturally occurring soluble form of mouse Toll-like receptor 4 inhibits lipopolysaccharide signalingQ40836924
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Cloning and expression analysis of two alternative splicing toll-like receptor 9 isoforms A and B in large yellow croaker, Pseudosciaena croceaQ42598837
Alternate transcription of the Toll-like receptor signaling cascadeQ43227064
Molecular cloning, characterization and expression analysis of TLR9, MyD88 and TRAF6 genes in common carp (Cyprinus carpio).Q44961108
Functional coupling of cleavage and polyadenylation with transcription of mRNA.Q46616243
A mutation in the largest subunit of RNA polymerase II alters RNA chain elongation in vitro.Q52451608
The CTD code.Q53963724
T cell activation regulates CD6 alternative splicing by transcription dynamics and SRSF1.Q54348065
Nuclear coupling: RNA processing reaches back to transcriptionQ78433053
Drosophila RNA polymerase II mutants that affect transcription elongationQ95819069
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An extensive network of coupling among gene expression machinesQ29547273
Phosphorylation and functions of the RNA polymerase II CTDQ29614764
The genome sequence of Atlantic cod reveals a unique immune systemQ31029462
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Histone deacetylase activity modulates alternative splicing.Q33818140
Elevated levels of the 64-kDa cleavage stimulatory factor (CstF-64) in lipopolysaccharide-stimulated macrophages influence gene expression and induce alternative poly(A) site selectionQ33990533
The RNA polymerase II CTD coordinates transcription and RNA processing.Q34303212
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Global impact of RNA polymerase II elongation inhibition on alternative splicing regulationQ34605595
In vivo degradation of RNA polymerase II largest subunit triggered by alpha-amanitinQ34606712
Evidence for evolving Toll-IL-1 receptor-containing adaptor molecule function in vertebrates.Q34610239
Limiting of the innate immune response by SF3A-dependent control of MyD88 alternative mRNA splicingQ35034303
Coupling transcription, splicing and mRNA exportQ35145838
Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signalingQ35566922
Toll-Like Receptor 9 Alternatively Spliced Isoform Negatively Regulates TLR9 Signaling in Teleost FishQ35586860
Transcriptional regulation in the innate immune systemQ35783438
Nuclear matrix-associated protein SMAR1 regulates alternative splicing via HDAC6-mediated deacetylation of Sam68.Q35818741
Multiple links between transcription and splicingQ35895223
Toll-like receptors in the pathogenesis of human diseaseQ35904386
The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleusQ36161960
A structural perspective of CTD functionQ36167411
Elongation by RNA polymerase II on chromatin templates requires topoisomerase activityQ36247792
BRD4 coordinates recruitment of pause release factor P-TEFb and the pausing complex NELF/DSIF to regulate transcription elongation of interferon-stimulated genesQ36978246
In vivo dynamics of RNA polymerase II transcription.Q37088096
Transcriptional control of the inflammatory responseQ37622051
The carboxy terminal domain of RNA polymerase II and alternative splicingQ37736900
Functional coupling of transcription and splicingQ38005818
Post-transcriptional regulation of gene expression in innate immunity.Q38214041
Cutting edge: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cellsQ38296679
Identification of a cyclin subunit required for the function of Drosophila P-TEFbQ38337012
Establishment of cell lines from a tropical grouper, Epinephelus awoara (Temminck & Schlegel), and their susceptibility to grouper irido- and nodavirusesQ39157198
Control of inducible gene expression by signal-dependent transcriptional elongationQ39285490
Camptothecin releases P-TEFb from the inactive 7SK snRNP complexQ39305987
DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation.Q39850003
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
toll-like receptorQ408004
NF-κBQ411114
alternative mRNA splicing, via spliceosomeQ21114084
P304page(s)e0163415
P577publication date2016-09-22
P1433published inPLOS OneQ564954
P1476titleAlternative Splicing of Toll-Like Receptor 9 Transcript in Teleost Fish Grouper Is Regulated by NF-κB Signaling via Phosphorylation of the C-Terminal Domain of the RPB1 Subunit of RNA Polymerase II
P478volume11