Human G(salpha) mutant causes pseudohypoparathyroidism type Ia/neonatal diarrhea, a potential cell-specific role of the palmitoylation cycle

scholarly article

Human G(salpha) mutant causes pseudohypoparathyroidism type Ia/neonatal diarrhea, a potential cell-specific role of the palmitoylation cycle is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2007PNAS..10417424M
P356DOI10.1073/PNAS.0708561104
P932PMC publication ID2077272
P698PubMed publication ID17962410
P5875ResearchGate publication ID5884291

P2093author name stringToshiro Fujita
Micheala A Aldred
Yasuhito Yuasa
Philippe Rondard
Noriko Makita
Taroh Iiri
Junichiro Sato
Hiroshi Fukamachi
Makiko Hashimoto
P2860cites workA novel mutation in the switch 3 region of Gsalpha in a patient with Albright hereditary osteodystrophy impairs GDP binding and receptor activationQ24310441
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The GTPase superfamily: conserved structure and molecular mechanismQ27860524
Characterization of Saccharomyces cerevisiae acyl-protein thioesterase 1, the enzyme responsible for G protein alpha subunit deacylation in vivoQ27939571
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Palmitoylation is required for signaling functions and membrane attachment of Gq alpha and Gs alphaQ28255860
Palmitoylation of intracellular signaling proteins: regulation and functionQ28266189
A Cytoplasmic Acyl-Protein Thioesterase That Removes Palmitate from G Protein α Subunits and p21RASQ28273568
Palmitoylation: policing protein stability and trafficQ28280080
Causal relationship between the loss of RUNX3 expression and gastric cancerQ28509530
Live cell imaging of Gs and the beta2-adrenergic receptor demonstrates that both alphas and beta1gamma7 internalize upon stimulation and exhibit similar trafficking patterns that differ from that of the beta2-adrenergic receptorQ28573455
Insights into G protein structure, function, and regulation.Q30336381
Mechanisms of disease: the role of GRK4 in the etiology of essential hypertension and salt sensitivityQ30441976
The expanding spectrum of G protein diseasesQ33547178
Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genomeQ33557797
Stimulation of beta-adrenergic receptors of S49 lymphoma cells redistributes the alpha subunit of the stimulatory G protein between cytosol and membranesQ34312140
Pathophysiological roles of G-protein-coupled receptor kinasesQ34418929
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An acquired hypocalciuric hypercalcemia autoantibody induces allosteric transition among active human Ca-sensing receptor conformations.Q35720141
Historical review: a brief history and personal retrospective of seven-transmembrane receptorsQ35847116
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Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteriaQ36200458
Thematic review series: lipid posttranslational modifications. Lysosomal metabolism of lipid-modified proteinsQ36455039
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Assembly and trafficking of heterotrimeric G proteinsQ36845087
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Runx3-/- gastric epithelial cells differentiate into intestinal type cellsQ40517145
A Novel Mutation Adjacent to the Switch III Domain of Gsαin a Patient with PseudohypoparathyroidismQ41084237
Reversible palmitoylation of signaling proteinsQ41382874
Rapid GDP release from Gs alpha in patients with gain and loss of endocrine functionQ41442871
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Separate GTP binding and GTPase activating domains of a G alpha subunitQ41508279
Modification of the function of pertussis toxin substrate GTP-binding protein by cholera toxin-catalyzed ADP-ribosylationQ41643635
Chemotactic peptide receptor-supported ADP-ribosylation of a pertussis toxin substrate GTP-binding protein by cholera toxin in neutrophil-type HL-60 cellsQ41758298
Coding GNAS mutations leading to hormone resistance impair in vitro agonist- and cholera toxin-induced adenosine cyclic 3',5'-monophosphate formation mediated by human XLalphas.Q42490986
Germline mosaicism for a GNAS1 mutation and Albright hereditary osteodystrophyQ43076226
Reconstitution of agonist-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11, and phospholipase C-beta 1Q43508385
The McCune-Albright syndrome: a lethal gene surviving by mosaicismQ43628624
Real-time visualization of a fluorescent G(alpha)(s): dissociation of the activated G protein from plasma membraneQ43865607
The effect of GTP and Mg2+ on the GTPase activity and the fluorescent properties of Go.Q45202534
G-protein diseases furnish a model for the turn-on switchQ46345189
Synthesis in Escherichia coli of GTPase-deficient mutants of Gs alphaQ54724996
GNAS1 lesions in pseudohypoparathyroidism Ia and Ic: genotype phenotype relationship and evidence of the maternal transmission of the hormonal resistanceQ55670473
CholeraQ57119004
Effects of Mg2+ and the beta gamma-subunit complex on the interactions of guanine nucleotides with G proteinsQ70322245
Pseudohypoparathyroidism, a novel mutation in the betagamma-contact region of Gsalpha impairs receptor stimulationQ71245866
A novel Gs alpha mutant in a patient with Albright hereditary osteodystrophy uncouples cell surface receptors from adenylyl cyclaseQ71650722
P433issue44
P407language of work or nameEnglishQ1860
P921main subjectdiarrheaQ40878
Albright's hereditary osteodystrophyQ4712685
P304page(s)17424-17429
P577publication date2007-10-25
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleHuman G(salpha) mutant causes pseudohypoparathyroidism type Ia/neonatal diarrhea, a potential cell-specific role of the palmitoylation cycle
P478volume104

Reverse relations

cites work (P2860)
Q37192455A Novel T55A Variant of Gs α Associated with Impaired cAMP Production, Bone Fragility, and Osteolysis
Q42380620Analysis of the V2 Vasopressin Receptor (V2R) Mutations Causing Partial Nephrogenic Diabetes Insipidus Highlights a Sustainable Signaling by a Non-peptide V2R Agonist
Q54467570Attenuated Desensitization of β-Adrenergic Receptor by Water-Soluble N-Nitrosamines That Induce S-Nitrosylation Without NO Release
Q93162304Cinacalcet corrects biased allosteric modulation of CaSR by AHH autoantibody
Q35515532Extra-long Gαs variant XLαs protein escapes activation-induced subcellular redistribution and is able to provide sustained signaling
Q35563016GNAS Spectrum of Disorders
Q35125525Identification of a novel mutation in a pseudohypoparathyroidism family
Q39593006Molecular basis of a novel oncogenic mutation in GNAO1
Q37359990Protein acyl thioesterases (Review).
Q37912382Protein palmitoylation and subcellular trafficking
Q28577831Regulation of RhoA signaling by the cAMP-dependent phosphorylation of RhoGDIα
Q26852157The GNAS complex locus and human diseases associated with loss-of-function mutations or epimutations within this imprinted gene
Q40649339V2 Vasopressin Receptor (V2R) Mutations in Partial Nephrogenic Diabetes Insipidus Highlight Protean Agonism of V2R Antagonists

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