| scholarly article | Q13442814 |
| P2093 | author name string | J S Alexander | |
| P Yi | |||
| L Schrott | |||
| T P Castor | |||
| P2860 | cites work | Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase | Q24292869 |
| Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors | Q24294213 | ||
| Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory | Q24645499 | ||
| APP processing in Alzheimer's disease | Q27694738 | ||
| ADAM19 is tightly associated with constitutive Alzheimer's disease APP alpha-secretase in A172 cells | Q28274661 | ||
| Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus | Q28592777 | ||
| AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss | Q29614850 | ||
| Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function | Q29614851 | ||
| APP processing and synaptic function | Q29615873 | ||
| Nociceptive and behavioural sensitisation by protein kinase Cepsilon signalling in the CNS. | Q30365485 | ||
| Blockade of PKC epsilon activation attenuates phorbol ester-induced increase of alpha-secretase-derived secreted form of amyloid precursor protein | Q31855663 | ||
| Progress in Alzheimer's disease | Q33943357 | ||
| Selective translocation of protein kinase C-delta in PC12 cells during nerve growth factor-induced neuritogenesis | Q34447989 | ||
| Comparison of pharmacological modulation of APP metabolism in primary chicken telencephalic neurons and in a human neuroglioma cell line | Q34586941 | ||
| Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease | Q34826547 | ||
| Substrate specificity and inducibility of TACE (tumour necrosis factor α-converting enzyme) revisited: the Ala-Val preference, and induced intrinsic activity | Q35572207 | ||
| Indolactam and benzolactam compounds as new medicinal leads with binding selectivity for C1 domains of protein kinase C isozymes. | Q35768317 | ||
| Tissue and cellular distribution of the extended family of protein kinase C isoenzymes | Q36531203 | ||
| Alzheimer disease--no target for statin treatment. A mini review | Q36634036 | ||
| Novel modulators of amyloid-beta precursor protein processing | Q36714447 | ||
| Isolation and characterization of the epsilon subspecies of protein kinase C from rat brain | Q36824769 | ||
| Isolation and characterization of delta-subspecies of protein kinase C from rat brain | Q36849137 | ||
| Progress toward a practical BACE-1 inhibitor. | Q36894647 | ||
| Cholesterol and statins in Alzheimer's disease: current controversies | Q37603783 | ||
| Protein kinase C as a peripheral biomarker for Alzheimer's disease | Q37628874 | ||
| Protein kinase Calpha: disease regulator and therapeutic target. | Q37647208 | ||
| Pharmacology of protein kinase C activators: cognition-enhancing and antidementic therapeutics | Q37728627 | ||
| Low-n oligomers as therapeutic targets of Alzheimer's disease | Q37829762 | ||
| γ-secretase inhibitors and modulators for the treatment of Alzheimer's disease: disappointments and hopes | Q37867706 | ||
| The role of phytochemicals in the treatment and prevention of dementia | Q37884566 | ||
| Activation of α-secretase cleavage | Q37924852 | ||
| Pharmacotherapies for Alzheimer's disease: beyond cholinesterase inhibitors | Q37971338 | ||
| Design of an orally efficacious hydroxyethylamine (HEA) BACE-1 inhibitor in a preclinical animal model | Q39656938 | ||
| Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease | Q39686268 | ||
| Reduction of beta-amyloid levels by novel protein kinase C(epsilon) activators | Q39784350 | ||
| New protein kinase C activator regulates amyloid precursor protein processing in vitro by increasing alpha-secretase activity | Q40103235 | ||
| Overexpression of amyloid precursor protein reduces epsilon protein kinase C levels | Q40167021 | ||
| Amyloid beta peptide directly inhibits PKC activation | Q40543309 | ||
| New amide-bearing benzolactam-based protein kinase C modulators induce enhanced secretion of the amyloid precursor protein metabolite sAPPalpha | Q40675732 | ||
| Age-related alteration of PKC, a key enzyme in memory processes: physiological and pathological examples | Q41745930 | ||
| Enhanced generation of Alzheimer's amyloid-beta following chronic exposure to phorbol ester correlates with differential effects on alpha and epsilon isozymes of protein kinase C. | Q41780891 | ||
| Evidence against roles for phorbol binding protein Munc13-1, ADAM adaptor Eve-1, or vesicle trafficking phosphoproteins Munc18 or NSF as phospho-state-sensitive modulators of phorbol/PKC-activated Alzheimer APP ectodomain shedding | Q41867455 | ||
| Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3. | Q42067413 | ||
| Benzolactam (BL) enhances sAPP secretion in fibroblasts and in PC12 cells | Q42471948 | ||
| Defective phorbol ester-stimulated secretion of beta-amyloid precursor protein from Alzheimer's disease fibroblasts | Q42524035 | ||
| Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf. | Q42808825 | ||
| Overexpression of protein kinase C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity | Q42810974 | ||
| Dual-target-directed 1,3-diphenylurea derivatives: BACE 1 inhibitor and metal chelator against Alzheimer's disease | Q42974334 | ||
| Purine derivatives as potent gamma-secretase modulators | Q43140894 | ||
| The amide hydrogen of (-)-indolactam-V and benzolactam-V8's plays a critical role in protein kinase C binding and tumor-promoting activities | Q43552134 | ||
| Protein kinase C epsilon suppresses Abeta production and promotes activation of alpha-secretase. | Q43684379 | ||
| Brain-derived neurotrophic factor stimulates beta-amyloid gene promoter activity by a Ras-dependent/AP-1-independent mechanism in SH-SY5Y neuroblastoma cells | Q43777371 | ||
| Identification of three additional members of rat protein kinase C family: delta-, epsilon- and zeta-subspecies | Q43834999 | ||
| Endothelial PKC delta activation attenuates neutrophil transendothelial migration | Q44005321 | ||
| Muscarine enhances soluble amyloid precursor protein secretion in human neuroblastoma SH-SY5Y by a pathway dependent on protein kinase C(alpha), src-tyrosine kinase and extracellular signal-regulated kinase but not phospholipase C. | Q44111144 | ||
| Role of protein kinase Calpha in the regulated secretion of the amyloid precursor protein | Q44334391 | ||
| Analysis of long-term cognitive-enhancing effects of bryostatin-1 on the rabbit (Oryctolagus cuniculus) nictitating membrane response. | Q44938183 | ||
| PKC ε activation prevents synaptic loss, Aβ elevation, and cognitive deficits in Alzheimer's disease transgenic mice | Q44962410 | ||
| Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses | Q46768341 | ||
| Decreased calcium/calmodulin-dependent protein kinase II and protein kinase C activities mediate impairment of hippocampal long-term potentiation in the olfactory bulbectomized mice | Q46974204 | ||
| PKC activators (phorbol ester or bryostatin) stimulate outgrowth of NGF-dependent neurites in a subline of PC12 cells | Q47810632 | ||
| Attenuated protein kinase C activity and translocation in Alzheimer's disease brain | Q48134687 | ||
| Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice. | Q51029182 | ||
| Cytosol protein kinase C downregulation in fibroblasts from Alzheimer's disease patients. | Q53207923 | ||
| Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo. | Q53274559 | ||
| Effect of methionine, glycine and serine on serine hydroxymethyltransferase activity in rat glioma and human neuroblastoma cells. | Q55491195 | ||
| Isolation and structure of bryostatin 1 | Q57255655 | ||
| Bryostatin 1 protects protein kinase C-delta from down-regulation in mouse keratinocytes in parallel with its inhibition of phorbol ester-induced differentiation | Q57997655 | ||
| Selective regulation of protein kinase C isoenzymes by oleic acid in human platelets | Q70589398 | ||
| Assessment of protein kinase C mRNA levels in Alzheimer's disease brains | Q71603312 | ||
| Compartmentation of the cerebellar cortex by protein kinase C delta | Q72586463 | ||
| Characterization and distribution of protein kinase C isoforms in human skin fibroblasts | Q72764897 | ||
| P433 | issue | 1 | |
| P304 | page(s) | 234-244 | |
| P577 | publication date | 2012-06-15 | |
| P1433 | published in | Journal of Molecular Neuroscience | Q15708870 |
| P1476 | title | Bryostatin-1 vs. TPPB: dose-dependent APP processing and PKC-α, -δ, and -ε isoform activation in SH-SY5Y neuronal cells | |
| P478 | volume | 48 |
| Q38738840 | Bryostatin and its synthetic analog, picolog rescue dermal fibroblasts from prolonged stress and contribute to survival and rejuvenation of human skin equivalents. |
| Q38816146 | C6 Glioma-Secreted NGF and FGF2 Regulate Neuronal APP Processing Through Up-Regulation of ADAM10 and Down-Regulation of BACE1, Respectively |
| Q35657890 | Common mechanisms of Alzheimer's disease and ischemic stroke: the role of protein kinase C in the progression of age-related neurodegeneration |
| Q37559812 | Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer's Disease |
| Q93057430 | Munc13 Is a Molecular Target of Bryostatin 1 |
| Q42496987 | PKC Activation Counteracts ADAM10 Deficit in HuD-Silenced Neuroblastoma Cells |
| Q38784086 | Protein Kinase C Activation as a Potential Therapeutic Strategy in Alzheimer's Disease: Is there a Role for Embryonic Lethal Abnormal Vision-like Proteins? |
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