| scholarly article | Q13442814 |
| P50 | author | Joydip Das | Q89132465 |
| Anamitra Ghosh | Q93057425 | ||
| P2093 | author name string | Peter M Blumberg | |
| Satyabrata Pany | |||
| Noemi Kedei | |||
| Youngki You | |||
| Agnes Czikora | |||
| Gary A Mitchell | |||
| Francisco A Blanco | |||
| P2860 | cites work | Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1 | Q24313621 |
| Crystal Structure and Allosteric Activation of Protein Kinase C βII | Q27666514 | ||
| UCSF Chimera--a visualization system for exploratory research and analysis | Q27860666 | ||
| Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction | Q27860958 | ||
| Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles | Q27863297 | ||
| Structural mechanism for lipid activation of the Rac-specific GAP, beta2-chimaerin | Q28289919 | ||
| Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming | Q28504670 | ||
| Munc13-1 is required for presynaptic long-term potentiation | Q28568366 | ||
| Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex | Q28569612 | ||
| Differential expression of two novel Munc13 proteins in rat brain | Q28572369 | ||
| The cerebellum-specific Munc13 isoform Munc13-3 regulates cerebellar synaptic transmission and motor learning in mice | Q28587834 | ||
| The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse | Q28593555 | ||
| AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility | Q29547658 | ||
| Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder | Q30840162 | ||
| Tumor promoter binding of the protein kinase C C1 homology domain peptides of RasGRPs, chimaerins, and Unc13s | Q31110926 | ||
| Bryostatin Effects on Cognitive Function and PKCɛ in Alzheimer's Disease Phase IIa and Expanded Access Trials | Q33708951 | ||
| Munc13-1 and Munc18-1 together prevent NSF-dependent de-priming of synaptic vesicles | Q33827873 | ||
| A simple analogue of tumor-promoting aplysiatoxin is an antineoplastic agent rather than a tumor promoter: development of a synthetically accessible protein kinase C activator with bryostatin-like activity. | Q34017564 | ||
| Chemistry and clinical biology of the bryostatins | Q34043857 | ||
| The intersection of amyloid beta and tau at synapses in Alzheimer's disease | Q34054680 | ||
| Scalable synthesis of bryostatin 1 and analogs, adjuvant leads against latent HIV. | Q47614932 | ||
| Neurodegeneration in C. elegans models of ALS requires TIR-1/Sarm1 immune pathway activation in neurons. | Q48177436 | ||
| Resveratrol inhibits phorbol ester-induced membrane translocation of presynaptic Munc13-1. | Q50888051 | ||
| Binding of [26-3H]bryostatin 1 and analogs to calcium-dependent and calcium-independent protein kinase C isozymes. | Q52542747 | ||
| Inhibition of Inflammation, Suppression of Matrix Metalloproteinases, Induction of Neurogenesis, and Antioxidant Property Make Bryostatin-1 a Therapeutic Choice for Multiple Sclerosis. | Q55483693 | ||
| A Randomized, Double-Blind, Placebo-Controlled, Phase II Study Assessing Safety, Tolerability, and Efficacy of Bryostatin in the Treatment of Moderately Severe to Severe Alzheimer's Disease | Q64236109 | ||
| Alcohol/cholecystokinin-evoked pancreatic acinar basolateral exocytosis is mediated by protein kinase C alpha phosphorylation of Munc18c | Q79836855 | ||
| UNC13A is a modifier of survival in amyotrophic lateral sclerosis | Q82687328 | ||
| C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis | Q34063137 | ||
| Genetic determinants of amyotrophic lateral sclerosis as therapeutic targets | Q34143210 | ||
| The chemistry and biology of the bryostatins: potential PKC inhibitors in clinical development | Q34268503 | ||
| Genetic heterogeneity of amyotrophic lateral sclerosis: implications for clinical practice and research | Q34401653 | ||
| Recent progress in the genetics of motor neuron disease | Q34402851 | ||
| Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions | Q34466011 | ||
| Differential regulation of gene expression by protein kinase C isozymes as determined by genome-wide expression analysis | Q34719591 | ||
| The synthetic bryostatin analog Merle 23 dissects distinct mechanisms of bryostatin activity in the LNCaP human prostate cancer cell line | Q34949801 | ||
| Move over protein kinase C, you've got company: alternative cellular effectors of diacylglycerol and phorbol esters. | Q34988000 | ||
| Bryostatin-1: a novel PKC inhibitor in clinical development | Q35634829 | ||
| Indolactam and benzolactam compounds as new medicinal leads with binding selectivity for C1 domains of protein kinase C isozymes. | Q35768317 | ||
| Bryostatin-1 vs. TPPB: dose-dependent APP processing and PKC-α, -δ, and -ε isoform activation in SH-SY5Y neuronal cells | Q36147173 | ||
| Loss of RAB-3/A in Caenorhabditis elegans and the mouse affects behavioral response to ethanol | Q36477139 | ||
| Bryostatin-1: pharmacology and therapeutic potential as a CNS drug. | Q36533472 | ||
| Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogs in LNCaP and U937 cancer cell lines provides insight into their differential mechanism of action | Q36557113 | ||
| Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming | Q36734003 | ||
| The life and death of protein kinase C. | Q37239605 | ||
| Neuroprotective versus tumorigenic protein kinase C activators | Q37398296 | ||
| The bryostatins | Q37448017 | ||
| Alzheimer's disease: synaptic dysfunction and Abeta | Q37636545 | ||
| Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN. | Q37691744 | ||
| C1 domains: structure and ligand-binding properties | Q38265623 | ||
| Characterization of the cysteine-rich region of the Caenorhabditis elegans protein Unc-13 as a high affinity phorbol ester receptor. Analysis of ligand-binding interactions, lipid cofactor requirements, and inhibitor sensitivity | Q38295646 | ||
| Axon guidance proteins in neurological disorders. | Q38376932 | ||
| Acute oral Bryostatin-1 administration improves learning deficits in the APP/PS1 transgenic mouse model of Alzheimer's disease | Q39071776 | ||
| Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release | Q41017986 | ||
| Evidence against roles for phorbol binding protein Munc13-1, ADAM adaptor Eve-1, or vesicle trafficking phosphoproteins Munc18 or NSF as phospho-state-sensitive modulators of phorbol/PKC-activated Alzheimer APP ectodomain shedding | Q41867455 | ||
| [3H]Phorbol 12,13-dibutyrate binding assay for protein kinase C and related proteins | Q42163750 | ||
| The pre-synaptic Munc13-1 binds alcohol and modulates alcohol self-administration in Drosophila. | Q42590696 | ||
| Curcumin Inhibits Protein Kinase Cα Activity by Binding to Its C1 Domain | Q42625879 | ||
| Synapsin is a novel Rab3 effector protein on small synaptic vesicles. II. Functional effects of the Rab3A-synapsin I interaction | Q44987419 | ||
| Bryostatin-1 restores hippocampal synapses and spatial learning and memory in adult fragile x mice | Q44995758 | ||
| Intramolecular occlusion of the diacylglycerol-binding site in the C1 domain of munc13-1. | Q45235934 | ||
| Caenorhabditis elegans rab-3 mutant synapses exhibit impaired function and are partially depleted of vesicles. | Q46113273 | ||
| A minimal domain responsible for Munc13 activity | Q46755751 | ||
| Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18. | Q47132424 | ||
| Synaptic weight set by Munc13-1 supramolecular assemblies. | Q47174177 | ||
| Critical Role of Trp-588 of Presynaptic Munc13-1 for Ligand Binding and Membrane Translocation. | Q47290370 | ||
| Munc13 proteins control regulated exocytosis in mast cells | Q47398975 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 27 | |
| P304 | page(s) | 3016-3030 | |
| P577 | publication date | 2019-06-20 | |
| P1433 | published in | Biochemistry | Q764876 |
| P1476 | title | Munc13 Is a Molecular Target of Bryostatin 1 | |
| P478 | volume | 58 |
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