review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1517/14728222.9.2.395 |
P698 | PubMed publication ID | 15934923 |
P2093 | author name string | Grahame J McKenzie | |
Brian R Champion | |||
Emmanuel Briend | |||
Yvette Stallwood | |||
Mamnunur Khan | |||
P2860 | cites work | CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex | Q22008610 |
Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase | Q24273416 | ||
The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice | Q24308721 | ||
Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins | Q24310048 | ||
LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation | Q24536102 | ||
p300 acts as a transcriptional coactivator for mammalian Notch-1 | Q24548267 | ||
SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation | Q24548288 | ||
Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex | Q24550850 | ||
The Notch1 receptor is cleaved constitutively by a furin-like convertase | Q24671866 | ||
Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex | Q24675233 | ||
Notch signaling: cell fate control and signal integration in development | Q27861061 | ||
Epsins: adaptors in endocytosis? | Q27939888 | ||
RNA interference | Q28131798 | ||
Fringe is a glycosyltransferase that modifies Notch | Q28143123 | ||
Chemical glycobiology | Q28206826 | ||
The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog | Q28207494 | ||
The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1 | Q28261520 | ||
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch | Q28286748 | ||
Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis | Q28286759 | ||
sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins | Q28512956 | ||
Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta | Q28646258 | ||
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival | Q29547865 | ||
Functional diversity of helper T lymphocytes | Q29619415 | ||
Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines | Q31793569 | ||
Transferrin-polycation conjugates as carriers for DNA uptake into cells | Q33562690 | ||
Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells | Q33742099 | ||
The notch signalling regulator fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DXD. | Q33909902 | ||
Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA | Q33980474 | ||
Suppressor T cells: Rebirth, function and homeostasis | Q34014450 | ||
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance | Q34111451 | ||
CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor | Q34116317 | ||
Transcriptional mechanisms underlying lymphocyte tolerance. | Q34135663 | ||
c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation | Q34157660 | ||
Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain | Q34189079 | ||
Notch1 and T-cell development: insights from conditional knockout mice | Q34207634 | ||
Toward the rational design of cell fate modifiers: notch signaling as a target for novel biopharmaceuticals | Q34316086 | ||
PKB/AKT: functional insights from genetic models | Q34389540 | ||
Numb antagonizes Notch signaling to specify sibling neuron cell fates | Q34392095 | ||
Therapeutic aspects of tolerance. | Q34441123 | ||
Control of T-cell activation by CD4+ CD25+ suppressor T cells | Q34448423 | ||
Structural conservation of Notch receptors and ligands | Q34489392 | ||
Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta | Q34517421 | ||
CSL-independent Notch signalling: a checkpoint in cell fate decisions during development? | Q34801905 | ||
Notch signalling in the regulation of peripheral T-cell function. | Q35090094 | ||
Powder and particle-mediated approaches for delivery of DNA and protein vaccines into the epidermis | Q35159097 | ||
DNA vaccination | Q35581126 | ||
Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance | Q35690984 | ||
Notch signaling in T- and B-cell development. | Q35692177 | ||
T-cell anergy | Q35692198 | ||
Notch signaling in lymphocyte development and function | Q35768919 | ||
Ubiquitin-protein ligases--novel therapeutic targets? | Q35794038 | ||
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation | Q36367099 | ||
Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus. | Q36369494 | ||
Induction of antigen-specific regulatory T cells following overexpression of a Notch ligand by human B lymphocytes | Q39997530 | ||
Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell-dependent mechanism. | Q40271483 | ||
In search of the Holy Grail (actively acquired immunologic tolerance). | Q40523856 | ||
Notch 1 signaling regulates peripheral T cell activation | Q40566978 | ||
c-Cbl binding and ubiquitin-dependent lysosomal degradation of membrane-associated Notch1. | Q40759027 | ||
Xenopus neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates Notch signaling. | Q40764200 | ||
Drosophila nicastrin is essential for the intramembranous cleavage of notch | Q41473368 | ||
Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate. | Q43806416 | ||
Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression | Q43806498 | ||
A secreted Delta1-Fc fusion protein functions both as an activator and inhibitor of Notch1 signaling | Q43972008 | ||
Regulation of notch signaling by o-linked fucose. | Q44277318 | ||
Evidence that C promoter-binding factor 1 binding is required for Notch-1-mediated repression of activator protein-1. | Q44674014 | ||
Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch. | Q45094726 | ||
Mastermind critically regulates Notch-mediated lymphoid cell fate decisions. | Q45345202 | ||
Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells | Q45863413 | ||
An activated form of Notch influences the choice between CD4 and CD8 T cell lineages | Q46109980 | ||
Neuralized functions as an E3 ubiquitin ligase during Drosophila development | Q47071824 | ||
Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor | Q47072716 | ||
Notch1 expression on T cells is not required for CD4+ T helper differentiation | Q47431184 | ||
Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ T cells | Q47438852 | ||
Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells | Q47619638 | ||
Immune modulation by silencing IL-12 production in dendritic cells using small interfering RNA. | Q47777723 | ||
Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1. | Q51063485 | ||
Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells. | Q52086944 | ||
Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor. | Q52223825 | ||
Notch1 is essential for postimplantation development in mice. | Q52512097 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 395-410 | |
P577 | publication date | 2005-04-01 | |
P1433 | published in | Expert Opinion on Therapeutic Targets | Q5421214 |
P1476 | title | Notch: a unique therapeutic target for immunomodulation | |
P478 | volume | 9 |