review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Arthur Christopoulos | Q18977850 |
Denise Wootten | Q43294588 | ||
Sebastian Furness | Q57072112 | ||
Patrick M. Sexton | Q39936838 | ||
P2093 | author name string | Patrick M Sexton | |
Sebastian G B Furness | |||
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Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype | Q22122487 | ||
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Expression cloning of a human corticotropin-releasing-factor receptor | Q24311371 | ||
Molecular recognition of corticotropin-releasing factor by its G-protein-coupled receptor CRFR1 | Q24314090 | ||
Cloning, characterization, and expression of a human calcitonin receptor from an ovarian carcinoma cell line | Q24337451 | ||
Structure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligand | Q27644056 | ||
Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor | Q27647464 | ||
Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain | Q27649890 | ||
Molecular recognition of parathyroid hormone by its G protein-coupled receptor | Q27650193 | ||
Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism | Q27664362 | ||
Molecular identification and analysis of a novel human corticotropin-releasing factor (CRF) receptor: the CRF2gamma receptor | Q28115064 | ||
N-terminal splice variants of the type I PACAP receptor: isolation, characterization and ligand binding/selectivity determinants | Q28139403 | ||
In vitro folding, functional characterization, and disulfide pattern of the extracellular domain of human GLP-1 receptor | Q28201065 | ||
Novel receptor partners and function of receptor activity-modifying proteins | Q28215813 | ||
Regulation of the coupling to different G proteins of rat corticotropin-releasing factor receptor type 1 in human embryonic kidney 293 cells | Q40536196 | ||
Different domains of the glucagon and glucagon-like peptide-1 receptors provide the critical determinants of ligand selectivity | Q40663308 | ||
Human CRF2 alpha and beta splice variants: pharmacological characterization using radioligand binding and a luciferase gene expression assay | Q40958147 | ||
Molecular cloning of two receptors from rat brain with high affinity for salmon calcitonin | Q41542401 | ||
N-terminal truncation of salmon calcitonin leads to calcitonin antagonists. Structure activity relationship of N-terminally truncated salmon calcitonin fragments in vitro and in vivo | Q41607432 | ||
Functional importance of a structurally distinct homodimeric complex of the family B G protein-coupled secretin receptor | Q41883095 | ||
Silencing of secretin receptor function by dimerization with a misspliced variant secretin receptor in ductal pancreatic adenocarcinoma | Q44138569 | ||
A soluble form of the first extracellular domain of mouse type 2beta corticotropin-releasing factor receptor reveals differential ligand specificity | Q44336537 | ||
8-37h-CGRP antagonizes actions of amylin on carbohydrate metabolism in vitro and in vivo | Q46437996 | ||
Dimerization of corticotropin-releasing factor receptor type 1 is not coupled to ligand binding | Q46880025 | ||
Chimeric human calcitonin and glucagon receptors reveal two dissociable calcitonin interaction sites | Q48075434 | ||
Function of the rat calcitonin receptors, C1a and C1b, expressed in Xenopus oocytes. | Q48946039 | ||
Transmembrane segment IV contributes a functionally important interface for oligomerization of the Class II G protein-coupled secretin receptor. | Q51795077 | ||
Differential intracellular signaling through PAC1 isoforms as a result of alternative splicing in the first extracellular domain and the third intracellular loop. | Q51798125 | ||
Molecular Identification and Analysis of a Novel Human Corticotropin-Releasing Factor (CRF) Receptor: The CRF2 Receptor | Q56601763 | ||
Alternative splicing of a 48-nucleotide exon generates two isoforms of the human calcitonin receptor | Q56607577 | ||
A new highly potent parathyroid hormone antagonist: [D-Trp12,Tyr34]bPTH-(7-34)NH2 | Q69838435 | ||
A fragment of vasoactive intestinal peptide, VIP(10-28), is an antagonist of VIP in the colon carcinoma cell line, HT29 | Q70159024 | ||
Functionally different isoforms of the human calcitonin receptor result from alternative splicing of the gene transcript | Q71523035 | ||
Full activation of chimeric receptors by hybrids between parathyroid hormone and calcitonin. Evidence for a common pattern of ligand-receptor interaction | Q71742566 | ||
Isoforms of the rat calcitonin receptor: consequences for ligand binding and signal transduction | Q72019750 | ||
Sustained activation of Erk1/2 MAPK and cell growth suppression by the insert-negative, but not the insert-positive isoform of the human calcitonin receptor | Q73040317 | ||
Localization of the domains involved in ligand binding and activation of the glucose-dependent insulinotropic polypeptide receptor | Q73370227 | ||
High potency antagonists of the pancreatic glucagon-like peptide-1 receptor | Q73596177 | ||
The N-terminal fragment of human parathyroid hormone receptor 1 constitutes a hormone binding domain and reveals a distinct disulfide pattern | Q74061883 | ||
Fish calcitonin receptor has novel features | Q80730274 | ||
Headless splice variant acting as dominant negative calcitonin receptor | Q81151571 | ||
Structural basis for hormone recognition by the Human CRFR2{alpha} G protein-coupled receptor | Q28296331 | ||
Alternative splicing of a 48-nucleotide exon generates two isoforms of the human calcitonin receptor | Q28300089 | ||
Critical contributions of amino-terminal extracellular domains in agonist binding and activation of secretin and vasoactive intestinal polypeptide receptors. Studies of chimeric receptors | Q28303314 | ||
Differential signal transduction by five splice variants of the PACAP receptor | Q28566746 | ||
Postprandial stimulation of insulin release by glucose-dependent insulinotropic polypeptide (GIP). Effect of a specific glucose-dependent insulinotropic polypeptide receptor antagonist in the rat | Q28579516 | ||
Identification of brain isoforms of the rat calcitonin receptor | Q28580007 | ||
The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints | Q29547321 | ||
Novel alternatively spliced exon in the extracellular ligand-binding domain of the pituitary adenylate cyclase-activating polypeptide (PACAP) type 1 receptor (PAC1R) selectively increases ligand affinity and alters signal transduction coupling durin | Q33181839 | ||
Modulation of corticotropin releasing factor (CRF) signaling through receptor splicing in mouse pituitary cell line AtT-20--emerging role of soluble isoforms. | Q33623010 | ||
A soluble mouse brain splice variant of type 2alpha corticotropin-releasing factor (CRF) receptor binds ligands and modulates their activity | Q33850519 | ||
Expression, purification, and characterization of a soluble form of the first extracellular domain of the human type 1 corticotropin releasing factor receptor | Q33953071 | ||
PAC1hop receptor activation facilitates catecholamine secretion selectively through 2-APB-sensitive Ca(2+) channels in PC12 cells | Q34044166 | ||
Importance of lipid-exposed residues in transmembrane segment four for family B calcitonin receptor homo-dimerization | Q34079450 | ||
Alternative splicing of CRH-R1 receptors in human and mouse skin: identification of new variants and their differential expression | Q34095571 | ||
The hop cassette of the PAC1 receptor confers coupling to Ca2+ elevation required for pituitary adenylate cyclase-activating polypeptide-evoked neurosecretion | Q34280490 | ||
A variant of the human corticotropin-releasing factor (CRF) receptor: cloning, expression and pharmacology | Q34315166 | ||
Cloning and characterization of the signal transduction of four splice variants of the human pituitary adenylate cyclase activating polypeptide receptor. Evidence for dual coupling to adenylate cyclase and phospholipase C. | Q34384700 | ||
Recognition in the face of diversity: interactions of heterotrimeric G proteins and G protein-coupled receptor (GPCR) kinases with activated GPCRs | Q34624051 | ||
A naturally occurring isoform inhibits parathyroid hormone receptor trafficking and signaling | Q35229970 | ||
Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screening. | Q35454522 | ||
The alternatively spliced type II corticotropin-releasing factor receptor, stably expressed in LLCPK-1 cells, is not well coupled to the G protein(s). | Q36688775 | ||
Signaling properties of mouse and human corticotropin-releasing factor (CRF) receptors: decreased coupling efficiency of human type II CRF receptor | Q36700621 | ||
Differential signaling and immediate-early gene activation by four splice variants of the human pituitary adenylate cyclase-activating polypeptide receptor (hPACAP-R). | Q36841864 | ||
CRF1 receptor splicing in epidermal keratinocytes: potential biological role and environmental regulations | Q37032694 | ||
Dimerization in the absence of higher-order oligomerization of the G protein-coupled secretin receptor | Q37177027 | ||
Soluble corticotropin-releasing hormone receptor 2alpha splice variant is efficiently translated but not trafficked for secretion | Q37328849 | ||
NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptor | Q37511744 | ||
Emerging role of alternative splicing of CRF1 receptor in CRF signaling. | Q37710423 | ||
Dominant negative action of an abnormal secretin receptor arising from mRNA missplicing in a gastrinoma | Q38292254 | ||
Structural determinants critical for localization and signaling within the seventh transmembrane domain of the type 1 corticotropin releasing hormone receptor: lessons from the receptor variant R1d. | Q39943150 | ||
Structural domains determining signalling characteristics of the CRH-receptor type 1 variant R1beta and response to PKC phosphorylation. | Q40072646 | ||
Differential responses of corticotropin-releasing hormone receptor type 1 variants to protein kinase C phosphorylation | Q40234783 | ||
Characterization of novel splice variants of the PAC1 receptor in human neuroblastoma cells: consequences for signaling by VIP and PACAP. | Q40361764 | ||
Paired cysteine mutagenesis to establish the pattern of disulfide bonds in the functional intact secretin receptor. | Q40467495 | ||
Differential signal transduction by six splice variants of the pituitary adenylate cyclase-activating peptide (PACAP) receptor. | Q40530544 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | G protein-coupled receptor | Q38173 |
P304 | page(s) | 98-109 | |
P577 | publication date | 2012-05-01 | |
P1433 | published in | British Journal of Pharmacology | Q919631 |
P1476 | title | Consequences of splice variation on Secretin family G protein-coupled receptor function | |
P478 | volume | 166 |
Q36860090 | Alternative Splicing of the Pituitary Adenylate Cyclase-Activating Polypeptide Receptor PAC1: Mechanisms of Fine Tuning of Brain Activity |
Q39293507 | Amylin |
Q48198655 | CGRP and its receptors |
Q39146023 | Central Control of Feeding Behavior by the Secretin, PACAP, and Glucagon Family of Peptides |
Q38696170 | Fish genomes provide novel insights into the evolution of vertebrate secretin receptors and their ligand. |
Q90700664 | Molecular Signature for Receptor Engagement in the Metabolic Peptide Hormone Amylin |
Q37635255 | Molecular mechanisms underlying physiological and receptor pleiotropic effects mediated by GLP-1R activation. |
Q55709770 | Neuropeptide G Protein-Coupled Receptors as Oncotargets. |
Q38274844 | PACAP receptor pharmacology and agonist bias: analysis in primary neurons and glia from the trigeminal ganglia and transfected cells |
Q36153216 | Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR review 1. |
Q41598194 | Phase-plate cryo-EM structure of a class B GPCR-G-protein complex |
Q48034068 | Pituitary adenylate cyclase-activating polypeptide receptors in the trigeminovascular system: implications for migraine |
Q36629283 | Receptor activity-modifying protein-dependent impairment of calcitonin receptor splice variant Δ(1-47)hCT((a)) function |
Q43238779 | Secretin family (Class B) G protein-coupled receptors - from molecular to clinical perspectives |
Q90913018 | The role of GPCRs in bone diseases and dysfunctions |
Q36834005 | Vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide, and their receptors and cancer |
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