| P2093 | author name string | Richard J Smeyne | |
| | Yun Jiao | |
| | Justin D Boyd | |
| | Kennie R Shepherd | |
| | Sally Slack | |
| | Haeman Jang | |
| | Ciaran Faherty | |
| P2860 | cites work | Astrocytes convert the parkinsonism inducing neurotoxin, MPTP, to its active metabolite, MPP+ | Q68821467 |
| | The acute effect on levels of catecholamines and metabolites in brain, of a single dose of MPTP in 8 strains of mice | Q69431808 |
| | Studies on the effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on central catecholamine neurons in C57BL/6 mice. Comparison with three other strains of mice | Q69897497 |
| | Studies on the melanin affinity of selegiline (deprenyl) and other amphetamine derivatives | Q70375249 |
| | MPTP- and MPP(+)-induced effects on body temperature exhibit age- and strain-dependence in mice | Q70839418 |
| | Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Q70951248 |
| | Identification of a glutathione-S-transferase effector domain for inhibition of jun kinase, by molecular dynamics | Q73854145 |
| | Parkinson's disease, pesticides, and glutathione transferase polymorphisms | Q22004263 |
| | Glutathione S-transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus | Q28208902 |
| | Inhibition of brain vesicular monoamine transporter (VMAT2) enhances 1-methyl-4-phenylpyridinium neurotoxicity in vivo in rat striata | Q28377237 |
| | Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases | Q28508252 |
| | Parkinson's disease: mechanisms and models | Q29547424 |
| | Etiology and pathogenesis of Parkinson's disease | Q33593402 |
| | Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease | Q33943273 |
| | Environmental enrichment in adulthood eliminates neuronal death in experimental Parkinsonism | Q33985962 |
| | alpha-Synuclein protects against oxidative stress via inactivation of the c-Jun N-terminal kinase stress-signaling pathway in neuronal cells | Q34109337 |
| | The last decade in Parkinson's disease research. Basic sciences | Q34366792 |
| | Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration | Q34983386 |
| | Neuroinflammatory processes in Parkinson's disease. | Q35094887 |
| | COX-2 and neurodegeneration in Parkinson's disease. | Q35171052 |
| | GSTpi expression mediates dopaminergic neuron sensitivity in experimental parkinsonism | Q35616756 |
| | Recent advances in research on Parkinson disease: synuclein and parkin | Q35681283 |
| | JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease | Q35736273 |
| | The MPTP model of Parkinson's disease | Q36080019 |
| | Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity | Q37683630 |
| | The herbicide paraquat induces dopaminergic nigral apoptosis through sustained activation of the JNK pathway. | Q40553539 |
| | MPTP, MPP+ and mitochondrial function | Q41382377 |
| | Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter. | Q42468902 |
| | Differential strain susceptibility following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration acts in an autosomal dominant fashion: quantitative analysis in seven strains of Mus musculus. | Q42471915 |
| | Monoamine oxidase-inhibition and MPTP-induced neurotoxicity in the non-human primate: comparison of rasagiline (TVP 1012) with selegiline | Q43804325 |
| | The role of cyclo-oxygenase 1 and 2 activity in prostaglandin E(2) secretion by cultured human adult microglia: implications for Alzheimer's disease | Q44148987 |
| | Relationship between cyclooxygenase-2 and nitric oxide synthase-2 in rat cortex after stress | Q44597471 |
| | SP600125, a new JNK inhibitor, protects dopaminergic neurons in the MPTP model of Parkinson's disease | Q44740801 |
| | Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain | Q45256207 |
| | Seizure-induced neuronal death is associated with induction of c-Jun N-terminal kinase and is dependent on genetic background. | Q45944012 |
| | Glia cell number modulates sensitivity to MPTP in mice | Q46514011 |
| | Neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and methamphetamine in several strains of mice | Q48139523 |
| | Differences in nigral neuron number and sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57/bl and CD-1 mice | Q48151484 |
| | The neurochemical and clinical effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in small animals | Q48407639 |
| | Differential neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in Swiss-Webster mice from different sources | Q48444205 |
| | Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice. | Q48478164 |
| | Expression of c-Jun in dopaminergic neurons of the substantia nigra in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice | Q48542762 |
| | Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter. | Q48631699 |
| | Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase | Q48681443 |
| | Time-course and dose-response study on the effects of chronic L-DOPA administration on striatal dopamine levels and dopamine transporter following MPTP toxicity | Q49124162 |
| | In vitro studies of striatal vesicles containing the vesicular monoamine transporter (VMAT2): rat versus mouse differences in sequestration of 1-methyl-4-phenylpyridinium. | Q51406427 |
| | MPTP susceptibility in the mouse: behavioral, neurochemical, and histological analysis of gender and strain differences. | Q53900769 |
| | Genetics of Parkinson's disease | Q67218920 |
| | Epidemiology of Parkinson's disease. | Q67401761 |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | substantia nigra | Q753278 |
| P1104 | number of pages | 10 | |
| P304 | page(s) | 107-116 | |
| P577 | publication date | 2007-08-09 | |
| P1433 | published in | Brain Research | Q4955782 |
| P1476 | title | Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta | |
| P478 | volume | 1175 | |