| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | William G. Kaelin | Q1603351 |
| P2860 | cites work | Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases | Q44385171 |
| TSC2 regulates VEGF through mTOR-dependent and -independent pathways | Q44574474 | ||
| Activation of HIF-1alpha mRNA by hypoxia and iron chelator in isolated rat carotid body | Q44925849 | ||
| JunD reduces tumor angiogenesis by protecting cells from oxidative stress | Q45060498 | ||
| Drosophila cyclin D/Cdk4 requires Hif-1 prolyl hydroxylase to drive cell growth | Q47071841 | ||
| Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5' enhancer | Q48010229 | ||
| Putative control of angiogenesis in hemangioblastomas by the von Hippel-Lindau tumor suppressor gene. | Q48593082 | ||
| Hypoxic induction of hypoxia-inducible factor-1alpha and oxygen-regulated gene expression in mitochondrial DNA-depleted HeLa cells. | Q51703687 | ||
| Identification and characterization of a nuclease specific for the 3' end of the U6 small nuclear RNA | Q71973635 | ||
| von Hippel-Lindau disease | Q73979850 | ||
| Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway | Q74485172 | ||
| Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function | Q22009393 | ||
| The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis | Q22009936 | ||
| HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing | Q24291102 | ||
| C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation | Q24291783 | ||
| A conserved family of prolyl-4-hydroxylases that modify HIF | Q24291794 | ||
| FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity | Q24291819 | ||
| A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation | Q24294741 | ||
| Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing | Q24296765 | ||
| Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling | Q24297062 | ||
| The use of dioxygen by HIF prolyl hydroxylase (PHD1) | Q24298554 | ||
| Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL | Q24299061 | ||
| FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor | Q24300161 | ||
| General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia | Q24315006 | ||
| Characterization of the VHL tumor suppressor gene product: localization, complex formation, and the effect of natural inactivating mutations | Q24317659 | ||
| Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha | Q24320267 | ||
| Inhibition of transcription elongation by the VHL tumor suppressor protein | Q24336629 | ||
| Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C | Q24336712 | ||
| Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2 | Q24523680 | ||
| Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300. | Q24534053 | ||
| Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha | Q24534120 | ||
| Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor | Q24536055 | ||
| von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination | Q24554216 | ||
| Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha | Q24554355 | ||
| HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation | Q24555773 | ||
| Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein | Q24563543 | ||
| The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins | Q24564802 | ||
| Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein | Q24599442 | ||
| Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex | Q24654714 | ||
| Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex | Q24655274 | ||
| HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia | Q24671941 | ||
| Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway | Q24672316 | ||
| The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases | Q24796635 | ||
| Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth | Q24800550 | ||
| Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response | Q27638869 | ||
| Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation | Q27860876 | ||
| Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor | Q28118068 | ||
| Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases | Q28118968 | ||
| Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family | Q28119190 | ||
| Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1 | Q28141355 | ||
| Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation | Q28188357 | ||
| Characterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins | Q38322876 | ||
| Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases | Q39855219 | ||
| Metabolism of Proline and the Hydroxyprolines | Q40121480 | ||
| Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected]. | Q40527027 | ||
| Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha | Q40608119 | ||
| The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen | Q40631949 | ||
| A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets. | Q40643741 | ||
| Hypoxic but not anoxic stabilization of HIF-1alpha requires mitochondrial reactive oxygen species | Q40698061 | ||
| HIF-1alpha-prolyl hydroxylase: molecular target of nitric oxide in the hypoxic signal transduction pathway | Q40720503 | ||
| Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain | Q40795310 | ||
| Identification of alternative spliced variants of human hypoxia-inducible factor-1alpha | Q40897164 | ||
| Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling | Q40966083 | ||
| Oxygen-regulated and transactivating domains in endothelial PAS protein 1: comparison with hypoxia-inducible factor-1alpha. | Q40980305 | ||
| Functional requirement of the hypoxia-responsive element in the activation of the inducible nitric oxide synthase promoter by the iron chelator desferrioxamine | Q41110961 | ||
| Nitric oxide contributes to behavioral, cellular, and developmental responses to low oxygen in Drosophila | Q41680296 | ||
| Prolyl 4-hydroxylases and their protein disulfide isomerase subunit | Q41730501 | ||
| Inhibition of collagen synthesis with prolyl 4-hydroxylase inhibitor improves left ventricular function and alters the pattern of left ventricular dilatation after myocardial infarction | Q43783271 | ||
| Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein | Q44043145 | ||
| The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma | Q44043146 | ||
| Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha | Q44108492 | ||
| Mammalian EGLN genes have distinct patterns of mRNA expression and regulation | Q44137583 | ||
| Characterization and comparative analysis of the EGLN gene family | Q28189003 | ||
| Molecular basis of the VHL hereditary cancer syndrome | Q28220414 | ||
| Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension | Q28244565 | ||
| Hypoxia induces type II NOS gene expression in pulmonary artery endothelial cells via HIF-1 | Q28263501 | ||
| Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia | Q28267951 | ||
| Role of hydrogen peroxide in hypoxia-induced erythropoietin production | Q28369115 | ||
| Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, [...] | Q28376328 | ||
| Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase | Q28506124 | ||
| Expression of the SM-20 gene promotes death in nerve growth factor-dependent sympathetic neurons | Q28569931 | ||
| Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation | Q28576297 | ||
| Induction of SM-20 in PC12 cells leads to increased cytochrome c levels, accumulation of cytochrome c in the cytosol, and caspase-dependent cell death | Q28577620 | ||
| Lethal paralysis of Caenorhabditis elegans by Pseudomonas aeruginosa | Q28776408 | ||
| Mitochondrial reactive oxygen species trigger hypoxia-induced transcription | Q29614203 | ||
| Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein | Q29615928 | ||
| Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein | Q29615931 | ||
| Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing | Q29617570 | ||
| Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes | Q29617594 | ||
| Hypoxia upregulates inducible (Type II) nitric oxide synthase in an HIF-1 dependent manner in rat pulmonary microvascular but not aortic smooth muscle cells | Q30472376 | ||
| SM-20 is a novel mitochondrial protein that causes caspase-dependent cell death in nerve growth factor-dependent neurons | Q31520793 | ||
| Molecular mechanism of hypoxia-inducible factor 1alpha -p300 interaction. A leucine-rich interface regulated by a single cysteine | Q31527917 | ||
| Accumulation of HIF-1alpha under the influence of nitric oxide. | Q31835101 | ||
| Perspectives on oxygen sensing | Q33718248 | ||
| Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression | Q34104247 | ||
| Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3alpha locus | Q34139027 | ||
| Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression | Q34770083 | ||
| The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity | Q35201819 | ||
| Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3. | Q35688102 | ||
| Hypoxia-inducible factor 1alpha protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations | Q35693266 | ||
| Oxygen sensing and HIF-1 activation does not require an active mitochondrial respiratory chain electron-transfer pathway. | Q35954913 | ||
| Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism | Q36174439 | ||
| Prolyl 4-hydroxylase, a target enzyme for drug development. Design of suppressive agents and the in vitro effects of inhibitors and proinhibitors | Q36469088 | ||
| Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia | Q36487258 | ||
| Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene | Q37285776 | ||
| Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein | Q37286026 | ||
| Functional analysis of an oxygen-regulated transcriptional enhancer lying 3' to the mouse erythropoietin gene | Q37630413 | ||
| P921 | main subject | proline hydroxylation | Q69994698 |
| P1104 | number of pages | 14 | |
| P304 | page(s) | 115-128 | |
| P577 | publication date | 2005-01-01 | |
| P1433 | published in | Annual Review of Biochemistry | Q567356 |
| P1476 | title | Proline hydroxylation and gene expression | |
| P478 | volume | 74 |
| Q52664656 | 2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2. |
| Q27335284 | A distributed chemosensory circuit for oxygen preference in C. elegans |
| Q24654396 | A gain-of-function mutation in the HIF2A gene in familial erythrocytosis |
| Q37187218 | A general map of iron metabolism and tissue-specific subnetworks |
| Q24308718 | A mitochondrial enzyme degrades carotenoids and protects against oxidative stress |
| Q24684178 | A novel erythrocytosis-associated PHD2 mutation suggests the location of a HIF binding groove |
| Q36652792 | A phenotypic perspective on Mammalian oxygen sensor candidates |
| Q24305030 | A ubiquitin ligase complex assembles linear polyubiquitin chains |
| Q46883054 | ARNT misbehavin' in diabetic beta cells |
| Q42365285 | Accelerated tumor growth under intermittent hypoxia is associated with hypoxia-inducible factor-1-dependent adaptive responses to hypoxia |
| Q39807372 | Activating transcription factor 2 increases transactivation and protein stability of hypoxia-inducible factor 1alpha in hepatocytes |
| Q34053479 | Activation of Hif1α by the prolylhydroxylase inhibitor dimethyoxalyglycine decreases radiosensitivity |
| Q91961385 | Activation of Hypoxia-Inducible Factor Signaling Modulates the RNA Protein Interactome in Caenorhabditis elegans |
| Q33626148 | Activation of the hypoxia-inducible factor pathway induced by prolyl hydroxylase domain 2 deficiency enhances the effect of running training in mice |
| Q39599144 | An activator of PHD2, KRH102140, decreases angiogenesis via inhibition of HIF-1α. |
| Q40088306 | An endoplasmic reticulum transmembrane prolyl 4-hydroxylase is induced by hypoxia and acts on hypoxia-inducible factor alpha |
| Q34309185 | An epigenetic perspective on the free radical theory of development |
| Q37686184 | An insertion/deletion polymorphism within the proximal promoter of EGLN2 is associated with susceptibility for gastric cancer in the Chinese population |
| Q34174184 | Analysis of hypoxia-inducible factor alpha polyploidization reveals adaptation to Tibetan Plateau in the evolution of schizothoracine fish |
| Q38805247 | Anti-angiogenic Therapy for Retinal Disease |
| Q27653157 | Asparagine beta-hydroxylation stabilizes the ankyrin repeat domain fold |
| Q24311481 | Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor |
| Q35683322 | Association of the von Hippel-Lindau protein with AUF1 and posttranscriptional regulation of VEGFA mRNA. |
| Q35828707 | BMP4, SCF, and hypoxia cooperatively regulate the expansion of murine stress erythroid progenitors |
| Q36967604 | Bach2 maintains T cells in a naive state by suppressing effector memory-related genes |
| Q89583690 | Bclaf1 is a direct target of HIF-1 and critically regulates the stability of HIF-1α under hypoxia |
| Q59793507 | Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal |
| Q41982167 | Can metabolic plasticity be a cause for cancer? Warburg-Waddington legacy revisited. |
| Q37054884 | Carrot and stick: HIF-alpha engages c-Myc in hypoxic adaptation |
| Q38433996 | Cellular and molecular mechanisms of inflammation-induced angiogenesis |
| Q82599104 | Chapter 13. Oxygen as a direct and indirect biological determinant in the vasculature |
| Q46752695 | Characterization of a novel Caenorhabditis elegans prolyl 4-hydroxylase with a unique substrate specificity and restricted expression in the pharynx and excretory duct |
| Q37301016 | Complex role of HIF in cancer: the known, the unknown, and the unexpected |
| Q43093361 | Computational analysis of prolyl hydroxylase domain-containing protein 2 (PHD2) mutations promoting polycythemia insurgence in humans. |
| Q33605183 | Conformational preferences of substrates for human prolyl 4-hydroxylase |
| Q39781855 | Decreasing intracellular superoxide corrects defective ischemia-induced new vessel formation in diabetic mice |
| Q37036114 | Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice. |
| Q36667150 | Detection of cytoplasmic glycosylation associated with hydroxyproline |
| Q34079232 | Detection of the onset of ischemia and carcinogenesis by hypoxia-inducible transcription factor-based in vivo bioluminescence imaging |
| Q39241653 | Determinants of hypoxia inducible factor (HIF) activity in the intestinal mucosa |
| Q36277024 | Developmental regulation of hypoxia-inducible factor 1 and prolyl-hydroxylases in pulmonary vascular smooth muscle cells |
| Q35839997 | Dietary phytochemicals regulate whole-body CYP1A1 expression through an arylhydrocarbon receptor nuclear translocator-dependent system in gut. |
| Q28397747 | Digoxin downregulates NDRG1 and VEGF through the inhibition of HIF-1α under hypoxic conditions in human lung adenocarcinoma A549 cells |
| Q35592005 | Dose-dependent effects of allopurinol on human foreskin fibroblast cells and human umbilical vein endothelial cells under hypoxia |
| Q38177357 | Drug discovery based on genetic and metabolic findings in schizophrenia |
| Q39690333 | Dynamic and Combinatorial Landscape of Histone Modifications during the Intraerythrocytic Developmental Cycle of the Malaria Parasite. |
| Q34320724 | Dynamics of the skeletal muscle secretome during myoblast differentiation |
| Q35821979 | E2-EPF UCP regulates stability and functions of missense mutant pVHL via ubiquitin mediated proteolysis |
| Q39164389 | Emerging role of dopamine in neovascularization of pheochromocytoma and paraganglioma |
| Q33614677 | Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells |
| Q57377918 | Erythropoietin: An Historical Overview of Physiology, Molecular Biology and Gene Regulation |
| Q34768709 | Experimental strategies for the identification and characterization of adhesive proteins in animals: a review |
| Q37165474 | Familial chronic myeloproliferative disorders: the state of the art. |
| Q36489143 | Fbx8 makes Arf6 refractory to function via ubiquitination. |
| Q34145988 | Functions of Danggui Buxue Tang, a Chinese Herbal Decoction Containing Astragali Radix and Angelicae Sinensis Radix, in Uterus and Liver are Both Estrogen Receptor-Dependent and -Independent |
| Q38518910 | Gene expression profiling reveals the profound upregulation of hypoxia-responsive genes in primary human astrocytes |
| Q27930957 | Genome-wide analysis identifies MYND-domain protein Mub1 as an essential factor for Rpn4 ubiquitylation |
| Q37062066 | Genome-wide analysis of HIF-2α chromatin binding sites under normoxia in human bronchial epithelial cells (BEAS-2B) suggests its diverse functions |
| Q36907933 | HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation |
| Q36609852 | HIF and fumarate hydratase in renal cancer |
| Q38112399 | HIF expression and the role of hypoxic microenvironments within primary tumours as protective sites driving cancer stem cell renewal and metastatic progression |
| Q35041362 | HIF-1α restricts NF-κB-dependent gene expression to control innate immunity signals |
| Q40085629 | HIF-dependent antitumorigenic effect of antioxidants in vivo |
| Q37209249 | HIF-independent role of prolyl hydroxylases in the cellular response to amino acids |
| Q27316863 | HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium |
| Q36493913 | HIFing the brakes: therapeutic opportunities for treatment of human malignancies |
| Q38066120 | HIFs, angiogenesis, and cancer |
| Q27939907 | Heme levels switch the function of Hap1 of Saccharomyces cerevisiae between transcriptional activator and transcriptional repressor |
| Q46316704 | Hypoxia Sensing in Plants: On a Quest for Ion Channels as Putative Oxygen Sensors. |
| Q41107802 | Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation. |
| Q24298032 | Hypoxia and cell cycle regulation of the von Hippel-Lindau tumor suppressor |
| Q24294275 | Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variant |
| Q38779835 | Hypoxia primes human normal prostate epithelial cells and cancer cell lines for the NLRP3 and AIM2 inflammasome activation |
| Q33619166 | Hypoxia regulates BMP4 expression in the murine spleen during the recovery from acute anemia |
| Q37373524 | Hypoxia signaling during intestinal ischemia and inflammation |
| Q42426199 | Hypoxia-Inducible Factor-1 in Physiological and Pathophysiological Angiogenesis: Applications and Therapies |
| Q26768230 | Hypoxia-Inducible Factors (HIFs) and Phosphorylation: Impact on Stability, Localization, and Transactivity |
| Q58425721 | Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62 |
| Q38907502 | Hypoxia-dependent regulation of inflammatory pathways in immune cells |
| Q35470449 | Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF. |
| Q37769765 | Hypoxia-inducible factor (HIF) and HIF-stabilizing agents in neonatal care |
| Q38113857 | Hypoxia-inducible factor (HIF) network: insights from mathematical models |
| Q36946632 | Hypoxia-inducible factor 1 upregulation of both VEGF and ANGPTL4 is required to promote the angiogenic phenotype in uveal melanoma |
| Q27824855 | Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer |
| Q40127751 | Hypoxia-inducible factor linked to differential kidney cancer risk seen with type 2A and type 2B VHL mutations. |
| Q35087102 | Hypoxia-inducible factor-2α and iron absorptive gene expression in Belgrade rat intestine |
| Q28303287 | Hypoxia-inducible factors in the kidney |
| Q38947313 | Hypoxia-inducible factors: key regulators of myeloid cells during inflammation |
| Q64058261 | Hypoxia/pseudohypoxia-mediated activation of hypoxia-inducible factor-1α in cancer |
| Q24301670 | IOP1, a novel hydrogenase-like protein that modulates hypoxia-inducible factor-1alpha activity |
| Q52668129 | Identification of allosteric disulfides from labile bonds in X-ray structures. |
| Q37752924 | Improved transplantation outcome by epigenetic changes |
| Q33784382 | In vivo imaging of HIF-active tumors by an oxygen-dependent degradation protein probe with an interchangeable labeling system |
| Q28484495 | In vivo imaging of brain ischemia using an oxygen-dependent degradative fusion protein probe |
| Q37567057 | Induction of altered gene expression profiles in cultured bovine granulosa cells at high cell density |
| Q34001546 | Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF. |
| Q27334849 | Insulin/IGF-1 and hypoxia signaling act in concert to regulate iron homeostasis in Caenorhabditis elegans |
| Q40825620 | Integrity of the prolyl hydroxylase domain protein 2:erythropoietin pathway in aging mice |
| Q37377055 | Interferon-gamma induces prolyl hydroxylase (PHD)3 through a STAT1-dependent mechanism in human endothelial cells |
| Q39562918 | Involvement of HIF-1α in MLCK-dependent endothelial barrier dysfunction in hypoxia |
| Q38503037 | Iron and colorectal cancer: evidence from in vitro and animal studies |
| Q92842540 | JmjC histone demethylases act as chromatin oxygen sensors |
| Q55418554 | Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis. |
| Q38952702 | Limb ischemia and vessel regeneration: Is there a role for VEGF? |
| Q37307464 | Mechanisms and function of substrate recruitment by F-box proteins. |
| Q24600512 | Metabolism of kidney cancer: from the lab to clinical practice |
| Q55273452 | Molecular cloning of phd1 and comparative analysis of phd1, 2, and 3 expression in Xenopus laevis. |
| Q37183447 | Molecular genetics of hereditary renal cancer: new genes and diagnostic and therapeutic opportunities |
| Q34248310 | Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production |
| Q42101114 | Multiple Components of the VHL Tumor Suppressor Complex Are Frequently Affected by DNA Copy Number Loss in Pheochromocytoma |
| Q24337524 | Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1 |
| Q35459859 | New insights into endocrine pancreatic development: the role of environmental factors |
| Q36378405 | Normal glucose uptake in the brain and heart requires an endothelial cell-specific HIF-1α-dependent function |
| Q44520861 | Overexpression of factor inhibiting HIF-1 enhances vessel maturation and tumor growth via platelet-derived growth factor-C. |
| Q47575205 | Oxidized low-density lipoprotein suppresses mouse granulosa cell differentiation through disruption of the hypoxia-inducible factor 1 pathway |
| Q36757465 | Oxygen regulates epithelial-to-mesenchymal transition: insights into molecular mechanisms and relevance to disease |
| Q36913094 | Oxygen sensing and hypoxia-induced responses |
| Q29617805 | Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway |
| Q36857204 | Oxygen, a source of life and stress |
| Q37081146 | Oxygen-dependent binding of Nro1 to the prolyl hydroxylase Ofd1 regulates SREBP degradation in yeast |
| Q36676446 | Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member |
| Q39968880 | PCAF is an HIF-1alpha cofactor that regulates p53 transcriptional activity in hypoxia. |
| Q53079637 | PERK/eIF2α signaling inhibits HIF-induced gene expression during the unfolded protein response via YB1-dependent regulation of HIF1α translation. |
| Q38735114 | PHD2 Is a Regulator for Glycolytic Reprogramming in Macrophages |
| Q60921025 | PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia (Review) |
| Q37202484 | PTM-Switchboard--a database of posttranslational modifications of transcription factors, the mediating enzymes and target genes |
| Q37760036 | Post-translational modifications in signal integration |
| Q24304828 | Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH) |
| Q28476679 | Prediction and analysis of protein hydroxyproline and hydroxylysine |
| Q92651401 | Primary endothelial cell-specific regulation of hypoxia-inducible factor (HIF)-1 and HIF-2 and their target gene expression profiles during hypoxia |
| Q37718440 | Prognostic value of plasma levels of HIF-1a and PGC-1a in breast cancer |
| Q36332904 | Proline-mediated proteasomal degradation of the prostate-specific tumor suppressor NKX3.1. |
| Q37374651 | Prolyl 4-hydroxylases, key enzymes in the synthesis of collagens and regulation of the response to hypoxia, and their roles as treatment targets |
| Q24300092 | Prolyl hydroxylase 3 interacts with Bcl-2 to regulate doxorubicin-induced apoptosis in H9c2 cells |
| Q24298610 | Prolyl hydroxylase domain protein 2 regulates the intracellular cyclic AMP level in cardiomyocytes through its interaction with phosphodiesterase 4D |
| Q35141643 | Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity |
| Q33850553 | Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase |
| Q38976653 | Prolyl-4-hydroxylase 2 enhances hypoxia-induced glioblastoma cell death by regulating the gene expression of hypoxia-inducible factor-α |
| Q26823693 | Protein degradation and the stress response |
| Q40097221 | Protein kinase C-mediated modulation of FIH-1 expression by the homeodomain protein CDP/Cut/Cux |
| Q42316992 | Proteomic analysis reveals diverse proline hydroxylation-mediated oxygen-sensing cellular pathways in cancer cells |
| Q37430973 | Pyruvate-fortified cardioplegia evokes myocardial erythropoietin signaling in swine undergoing cardiopulmonary bypass |
| Q36026989 | RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect |
| Q24616197 | Radiosensitization and stromal imaging response correlates for the HIF-1 inhibitor PX-478 given with or without chemotherapy in pancreatic cancer |
| Q35676210 | Reduced levels of ATF-2 predispose mice to mammary tumors. |
| Q36485190 | Regulation of angiogenesis by hypoxia-inducible factor 1. |
| Q35524558 | Regulation of the Sre1 hypoxic transcription factor by oxygen-dependent control of DNA binding |
| Q36919710 | Regulation of tissue perfusion in mammals by hypoxia-inducible factor 1. |
| Q46755076 | Remote renal preconditioning-induced cardioprotection: a key role of hypoxia inducible factor-prolyl 4-hydroxylases |
| Q37400584 | Renal involvement in tuberous sclerosis complex and von Hippel-Lindau disease: shared disease mechanisms? |
| Q35610555 | Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation |
| Q33960117 | Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling. |
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