| scholarly article | Q13442814 |
| P50 | author | David Gems | Q5234076 |
| P2093 | author name string | Daniel Ackerman | |
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| Identification of a hypoxia response element in the transferrin receptor gene | Q78122337 | ||
| An iron enhancer element in the FTN-1 gene directs iron-dependent expression in Caenorhabditis elegans intestine | Q79911440 | ||
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| Two distinct roles for EGL-9 in the regulation of HIF-1-mediated gene expression in Caenorhabditis elegans | Q37425018 | ||
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| HIF-1 modulates longevity and healthspan in a temperature-dependent manner | Q37693738 | ||
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| Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance | Q38337791 | ||
| Cytosolic aconitase and ferritin are regulated by iron in Caenorhabditis elegans | Q38360851 | ||
| HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice. | Q42171228 | ||
| A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans. | Q42966749 | ||
| Transcriptional regulation and life-span modulation of cytosolic aconitase and ferritin genes in C.elegans | Q45029355 | ||
| JunD reduces tumor angiogenesis by protecting cells from oxidative stress | Q45060498 | ||
| Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway | Q46102898 | ||
| DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans | Q46465060 | ||
| Restless legs syndrome-associated MEIS1 risk variant influences iron homeostasis | Q46606396 | ||
| SMK-1, an essential regulator of DAF-16-mediated longevity | Q47069047 | ||
| Roles of the HIF-1 hypoxia-inducible factor during hypoxia response in Caenorhabditis elegans. | Q47069395 | ||
| The C. elegans MDL-1 and MXL-1 proteins can functionally substitute for vertebrate MAD and MAX | Q28511983 | ||
| Autophagy genes are essential for dauer development and life-span extension in C. elegans | Q29614180 | ||
| PCR fusion-based approach to create reporter gene constructs for expression analysis in transgenic C. elegans | Q29616765 | ||
| Maintenance of C. elegans | Q29617844 | ||
| daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans | Q29618073 | ||
| Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor | Q29619759 | ||
| Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling | Q29619762 | ||
| Balancing acts: molecular control of mammalian iron metabolism | Q29620380 | ||
| Selection and validation of a set of reliable reference genes for quantitative sod gene expression analysis in C. elegans | Q30840424 | ||
| Matrix and Steiner-triple-system smart pooling assays for high-performance transcription regulatory network mapping | Q33288695 | ||
| ELT-2 is the predominant transcription factor controlling differentiation and function of the C. elegans intestine, from embryo to adult. | Q33396126 | ||
| The HIF-1 hypoxia-inducible factor modulates lifespan in C. elegans | Q33487151 | ||
| C. elegans SWAN-1 Binds to EGL-9 and regulates HIF-1-mediated resistance to the bacterial pathogen Pseudomonas aeruginosa PAO1. | Q33701707 | ||
| Chromatin regulation and sumoylation in the inhibition of Ras-induced vulval development in Caenorhabditis elegans | Q33899619 | ||
| Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF. | Q34001546 | ||
| Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity | Q34006688 | ||
| Intracellular iron transport and storage: from molecular mechanisms to health implications | Q34100135 | ||
| Regulation of ferritin genes and protein | Q34126332 | ||
| DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO | Q34175789 | ||
| Iron metabolism: iron deficiency and iron overload | Q34433362 | ||
| The dauerlarva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans | Q34520955 | ||
| Stress resistance as a determinate of C. elegans lifespan | Q34547047 | ||
| Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions | Q34653028 | ||
| The role of iron in cell cycle progression and the proliferation of neoplastic cells | Q34872120 | ||
| Antioxidant defense and aging in C. elegans: is the oxidative damage theory of aging wrong? | Q34978910 | ||
| Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). | Q35826597 | ||
| A C. elegans Myc-like network cooperates with semaphorin and Wnt signaling pathways to control cell migration | Q36143512 | ||
| Proline hydroxylation and gene expression | Q36161153 | ||
| PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a). | Q36497447 | ||
| The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia | Q36530182 | ||
| Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia. | Q36542391 | ||
| Evolutionary conservation of regulated longevity assurance mechanisms | Q36570563 | ||
| Autophagy, ageing and apoptosis: the role of oxidative stress and lysosomal iron | Q36738248 | ||
| Dauer | Q36995488 | ||
| Role of the hypoxia inducible factors HIF in iron metabolism. | Q37062790 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Caenorhabditis elegans | Q91703 |
| hypoxia | Q105688 | ||
| preproinsulin | Q7240673 | ||
| P304 | page(s) | e1002498 | |
| P577 | publication date | 2012-01-01 | |
| P1433 | published in | PLOS Genetics | Q1893441 |
| P1476 | title | Insulin/IGF-1 and hypoxia signaling act in concert to regulate iron homeostasis in Caenorhabditis elegans | |
| P478 | volume | 8 |
| Q34415892 | Amino acids and TOR signaling promote prothoracic gland growth and the initiation of larval molts in the tobacco hornworm Manduca sexta |
| Q27317294 | CEP-1, the Caenorhabditis elegans p53 homolog, mediates opposing longevity outcomes in mitochondrial electron transport chain mutants |
| Q48911542 | Caenorhabditis elegans: an old genetic model can learn new epigenetic tricks. |
| Q36244852 | Cellular sensing and transport of metal ions: implications in micronutrient homeostasis. |
| Q90069130 | Chronic Pressure Overload Results in Deficiency of Mitochondrial Membrane Transporter ABCB7 Which Contributes to Iron Overload, Mitochondrial Dysfunction, Metabolic Shift and Worsens Cardiac Function |
| Q38152477 | Coupling heme and iron metabolism via ferritin H chain |
| Q27343881 | EGL-9 controls C. elegans host defense specificity through prolyl hydroxylation-dependent and -independent HIF-1 pathways |
| Q34408851 | Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegans |
| Q27333095 | Genome-wide microarrray analysis reveals roles for the REF-1 family member HLH-29 in ferritin synthesis and peroxide stress response |
| Q93043704 | Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy |
| Q36353620 | Increased serum hepcidin levels in subjects with the metabolic syndrome: a population study |
| Q36410041 | Inhibition of elongin C promotes longevity and protein homeostasis via HIF-1 in C. elegans |
| Q64086908 | Iron Metabolism of the Skeletal Muscle and Neurodegeneration |
| Q36875611 | Iron Overload Coordinately Promotes Ferritin Expression and Fat Accumulation in Caenorhabditis elegans |
| Q37002558 | Iron absorption in Drosophila melanogaster |
| Q33606421 | Loss-of-function of β-catenin bar-1 slows development and activates the Wnt pathway in Caenorhabditis elegans |
| Q90649812 | Low Concentrations of Caffeine and Its Analogs Extend the Lifespan of Caenorhabditis elegans by Modulating IGF-1-Like Pathway |
| Q37671514 | MDL-1, a growth- and tumor-suppressor, slows aging and prevents germline hyperplasia and hypertrophy in C. elegans. |
| Q36253932 | Manipulation of in vivo iron levels can alter resistance to oxidative stress without affecting ageing in the nematode C. elegans |
| Q33658871 | Mechanisms of iron metabolism in Caenorhabditis elegans |
| Q83228002 | NHR-14 loss of function couples intestinal iron uptake with innate immunity in through PQM-1 signaling |
| Q28079796 | New perspectives on the molecular basis of the interaction between oxygen homeostasis and iron metabolism |
| Q92258649 | Production of YP170 Vitellogenins Promotes Intestinal Senescence in Caenorhabditis elegans |
| Q52727060 | Reconstructing a metazoan genetic pathway with transcriptome-wide epistasis measurements. |
| Q90338754 | Resistin hormone in diabetic kidney disease and its relation to iron status and hepcidin |
| Q37691144 | The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans |
| Q33817822 | Ube2g2-gp78-mediated HERP polyubiquitylation is involved in ER stress recovery |
| Q49585703 | hmSOD1 gene mutation-induced disturbance in iron metabolism is mediated by impairment of Akt signalling pathway. |
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