daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans

scientific article (publication date: 11 December 2001)

daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0960-9822(01)00594-2
P3181OpenCitations bibliographic resource ID714933
P698PubMed publication ID11747825

P50authorThomas JohnsonQ42883774
P2093author name stringS T Henderson
P2860cites workAkt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factorQ22009126
Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stressQ24564321
A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegansQ24603590
Aging: a theory based on free radical and radiation chemistryQ27860549
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegansQ28131830
Genetic pathways that regulate ageing in model organismsQ28138437
daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegansQ28611332
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervalsQ29547713
Why do we age?Q29615672
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegansQ29617059
The genetics of caloric restriction in Caenorhabditis elegansQ29617240
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signalingQ29619762
Gerontogenes mediate health and longevity in nematodes through increasing resistance to environmental toxins and stressorsQ34071487
Genetic analysis of life-span in Caenorhabditis elegansQ36318911
Mechanisms and evolution of agingQ41003075
Genetic analysis of ageing: role of oxidative damage and environmental stresses.Q41010065
Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequenceQ42472986
Extension of Life-Span with Superoxide Dismutase/Catalase MimeticsQ62472542
Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of agingQ63951809
Adaptation to oxidative stress in young, but not in mature or old, Caenorhabditis elegansQ72222026
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectCaenorhabditis elegansQ91703
Forkhead box protein O CELE_R13H8.1Q29795009
P304page(s)1975-1980
P577publication date2001-12-01
P1433published inCurrent BiologyQ1144851
P1476titledaf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans
P478volume11

Reverse relations

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Q36561507Genome-wide endogenous DAF-16/FOXO recruitment dynamics during lowered insulin signalling in C. elegans
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Q36083338Gravity force transduced by the MEC-4/MEC-10 DEG/ENaC channel modulates DAF-16/FoxO activity in Caenorhabditis elegans
Q36334971Green Tea Extract Induces the Resistance of Caenorhabditis elegans against Oxidative Stress
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Q37693738HIF-1 modulates longevity and healthspan in a temperature-dependent manner
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Q42132873Host translational inhibition by Pseudomonas aeruginosa Exotoxin A Triggers an immune response in Caenorhabditis elegans
Q47069404Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation
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Q64259170Ingredients in Zijuan Pu'er Tea Extract Alleviate β-Amyloid Peptide Toxicity in a Model of Alzheimer's Disease Likely through DAF-16
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Q36488671Insulin signaling in Caenorhabditis elegans regulates both endocrine-like and cell-autonomous outputs
Q33684279Insulin signaling promotes germline proliferation in C. elegans
Q46627365Insulin-like signaling negatively regulates muscle arm extension through DAF-12 in Caenorhabditis elegans
Q27334849Insulin/IGF-1 and hypoxia signaling act in concert to regulate iron homeostasis in Caenorhabditis elegans
Q64076625Insulin/IGF-1R, SIRT1, and FOXOs Pathways-An Intriguing Interaction Platform for Bone and Osteosarcoma
Q35554316Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans
Q37585122Insulin/IGF1 signaling inhibits age-dependent axon regeneration
Q28305190Integrating the stress response: lessons for neurodegenerative diseases from C. elegans
Q37262814Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO.
Q28507004Integration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity
Q44412850Intermittent fasting and dietary supplementation with 2‐deoxy‐D‐glucose improve functional and metabolic cardiovascular risk factors in rats
Q34361218Intracellular protein glycosylation modulates insulin mediated lifespan in C.elegans
Q28386928Involvement of the up-regulated FoxO1 expression in follicular granulosa cell apoptosis induced by oxidative stress
Q41949373Isotopic ratio outlier analysis global metabolomics of Caenorhabditis elegans
Q33934548JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.
Q34765402Juvenile hormone and insulin regulate trehalose homeostasis in the red flour beetle, Tribolium castaneum.
Q46704659LET-60 RAS modulates effects of insulin/IGF-1 signaling on development and aging in Caenorhabditis elegans
Q37189208Life-span extension from hypoxia in Caenorhabditis elegans requires both HIF-1 and DAF-16 and is antagonized by SKN-1
Q52039780Lifespan and dauer regulation by tissue-specific activities of Caenorhabditis elegans DAF-18.
Q27324080Lifespan-extending effects of royal jelly and its related substances on the nematode Caenorhabditis elegans
Q38673046Lifespan-regulating genes in C. elegans
Q33942347Light and pheromone-sensing neurons regulates cold habituation through insulin signalling in Caenorhabditis elegans
Q35970467Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence
Q26773901Long live FOXO: unraveling the role of FOXO proteins in aging and longevity
Q25255758Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent translocation of DAF-16/FOXO to the cytoplasm
Q33863373Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands
Q36132307Longevity Genes Revealed by Integrative Analysis of Isoform-Specific daf-16/FoxO Mutants of Caenorhabditis elegans
Q35078356Longevity and heat stress regulation in Caenorhabditis elegans
Q33315298Longevity and resistance to stress correlate with DNA repair capacity in Caenorhabditis elegans
Q35254761Longevity and stress in Caenorhabditis elegans
Q34757207Longevity genes in the nematode Caenorhabditis elegans also mediate increased resistance to stress and prevent disease.
Q92028301Longevity: Lesson from Model Organisms
Q27301833Loss of C. elegans GON-1, an ADAMTS9 Homolog, Decreases Secretion Resulting in Altered Lifespan and Dauer Formation
Q54967620Lowbush cranberry acts through DAF-16/FOXO signaling to promote increased lifespan and axon branching in aging posterior touch receptor neurons.
Q54978541MPK-1/ERK pathway regulates DNA damage response during development through DAF-16/FOXO.
Q28246430Mammalian SIRT1 represses forkhead transcription factors
Q28077338Mechanisms of aging-related proteinopathies in Caenorhabditis elegans
Q87981906Metabolic shift from glycogen to trehalose promotes lifespan and healthspan in Caenorhabditis elegans
Q89012051Methyl 3,4-Dihydroxybenzoate Enhances Resistance to Oxidative Stressors and Lifespan in C. elegans Partially via daf-2/daf-16
Q36209138Methylation by Set9 modulates FoxO3 stability and transcriptional activity.
Q93217116MiDaf16-like and MiSkn1-like gene families are reliable targets to develop biotechnological tools for the control and management of Meloidogyne incognita
Q41882618MicroRNA mir-34 provides robustness to environmental stress response via the DAF-16 network in C. elegans
Q36955062MicroRNAs and the genetic network in aging.
Q40139530Mitochondrial dysfunction, oxidative stress, and neurodegeneration elicited by a bacterial metabolite in a C. elegans Parkinson's model
Q27314783Mitochondrial function is required for secretion of DAF-28/insulin in C. elegans
Q34767374Mitochondrial longevity pathways
Q60044019Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways
Q28255998Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
Q36315295Modulation of Caenorhabditis elegans infection sensitivity by the LIN-7 cell junction protein
Q89266567Modulation of caveolae by insulin/IGF-1 signaling regulates aging of Caenorhabditis elegans
Q50187389Modulatory upregulation of an insulin peptide gene by different pathogens in C. elegans.
Q33891308Molecular characterization of numr-1 and numr-2: genes that increase both resistance to metal-induced stress and lifespan in Caenorhabditis elegans
Q37245881Molecular cloning and DNA binding characterization of DAF-16 orthologs from Ancylostoma hookworms.
Q36829270Molecular signaling involved in regulating feeding and other motivated behaviors
Q34321472Monascus-fermented dioscorea enhances oxidative stress resistance via DAF-16/FOXO in Caenorhabditis elegans
Q37585797NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans
Q37137329NSBP-1 mediates the effects of cholesterol on insulin/IGF-1 signaling in Caenorhabditis elegans.
Q100415730NemaLife chip: a micropillar-based microfluidic culture device optimized for aging studies in crawling C. elegans
Q42443115Neuroendocrine signals modulate the innate immunity of Caenorhabditis elegans through insulin signaling
Q37279423Neuronal ROS signaling rather than AMPK/sirtuin-mediated energy sensing links dietary restriction to lifespan extension
Q35650853Neuronal and molecular substrates for optimal foraging in Caenorhabditis elegans
Q35125807New genes that extend Caenorhabditis elegans' lifespan in response to reproductive signals
Q91915881New label-free automated survival assays reveal unexpected stress resistance patterns during C. elegans aging
Q37581650Non-linear impact of glutathione depletion on C. elegans life span and stress resistance
Q36109887Non-transcriptional Function of FOXO1/DAF-16 Contributes to Translesion DNA Synthesis
Q42693068Nonautonomous regulation of neuronal migration by insulin signaling, DAF-16/FOXO, and PAK-1
Q27349004Nucleolar proteins suppress Caenorhabditis elegans innate immunity by inhibiting p53/CEP-1
Q24288717OASIS: online application for the survival analysis of lifespan assays performed in aging research
Q46430310Octopamine enhances oxidative stress resistance through the fasting-responsive transcription factor DAF-16/FOXO in C. elegans
Q47097416Omics Approaches for Identifying Physiological Adaptations to Genome Instability in Aging
Q55432540Opposing roles of microRNA Argonautes during Caenorhabditis elegans aging.
Q90727479Overcoming Autofluorescence to Assess GFP Expression During Normal Physiology and Aging in Caenorhabditis elegans
Q37387918Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1.
Q27342393PDP-1 links the TGF-β and IIS pathways to regulate longevity, development, and metabolism
Q44731575PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans
Q42585902PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity
Q36974448Pan-neuronal expression of APL-1, an APP-related protein, disrupts olfactory, gustatory, and touch plasticity in Caenorhabditis elegans
Q93051373Pervasive Positive and Negative Feedback Regulation of Insulin-Like Signaling in Caenorhabditis elegans
Q37337188Pharmacogenetic analysis of lithium-induced delayed aging in Caenorhabditis elegans
Q36553629Pharmacological lifespan extension of invertebrates
Q33549702Phenotypic covariance of longevity, immunity and stress resistance in the caenorhabditis nematodes
Q38071570Physiological functions of protein kinase D in vivo.
Q39088167Plant-parasitic nematodes: towards understanding molecular players in stress responses
Q39916580Positive and negative feedback regulates the transcription factor FOXL2 in response to cell stress: evidence for a regulatory imbalance induced by disease-causing mutations
Q27346904Prohibitin-mediated lifespan and mitochondrial stress implicate SGK-1, insulin/IGF and mTORC2 in C. elegans
Q92088136Prolonged quiescence delays somatic stem cell-like divisions in Caenorhabditis elegans and is controlled by insulin signaling
Q39752332Properties, regulation, and in vivo functions of a novel protein kinase D: Caenorhabditis elegans DKF-2 links diacylglycerol second messenger to the regulation of stress responses and life span
Q30489976Proteasomal regulation of the hypoxic response modulates aging in C. elegans
Q36220305Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan
Q27318409Pseudomonas aeruginosa suppresses host immunity by activating the DAF-2 insulin-like signaling pathway in Caenorhabditis elegans
Q36761262Public and private mechanisms of life extension in Caenorhabditis elegans
Q35946175RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling in Caenorhabditis elegans
Q37143073RNA helicase SACY-1 is required for longevity caused by various genetic perturbations in Caenorhabditis elegans.
Q34986923RNAi screens to identify components of gene networks that modulate aging in Caenorhabditis elegans
Q38042425ROS in aging Caenorhabditis elegans: damage or signaling?
Q39103593Receptor Guanylyl Cyclases in Sensory Processing.
Q36543140Reconstruction of the insulin-like signalling pathway of Haemonchus contortus
Q37989767Red mold, diabetes, and oxidative stress: a review.
Q47069491Reduced expression of the Caenorhabditis elegans p53 ortholog cep-1 results in increased longevity
Q29619759Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor
Q35749589Regulation of Caenorhabditis elegans lifespan by a proteasomal E3 ligase complex
Q37467624Regulation of DAF-16-mediated Innate Immunity in Caenorhabditis elegans
Q50897629Regulation of Lysosomal Function by the DAF-16 Forkhead Transcription Factor Couples Reproduction to Aging in Caenorhabditis elegans.
Q36673555Regulation of longevity by the reproductive system
Q36835699Regulation of oxidative stress by the anti-aging hormone klotho
Q33431583Regulation of the longevity response to temperature by thermosensory neurons in Caenorhabditis elegans
Q27334743Repression of a potassium channel by nuclear hormone receptor and TGF-β signaling modulates insulin signaling in Caenorhabditis elegans
Q90261920Repurposing bioactive compounds for treating multidrug-resistant pathogens
Q35527215Rifampicin reduces advanced glycation end products and activates DAF-16 to increase lifespan in Caenorhabditis elegans
Q35010485Role of insulin/insulin-like growth factor 1 signaling pathway in longevity.
Q39481696Rosmarinus officinalis L. increases Caenorhabditis elegans stress resistance and longevity in a DAF-16, HSF-1 and SKN-1-dependent manner.
Q24658178SHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegans
Q39896060SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response
Q39988144SKN-1-independent transcriptional activation of glutathione S-transferase 4 (GST-4) by EGF signaling
Q33690581SLR-2 and JMJC-1 regulate an evolutionarily conserved stress-response network
Q42736661Secondary metabolites of Pseudomonas fluorescens CHA0 drive complex non-trophic interactions with bacterivorous nematodes
Q46969722Selenite protects Caenorhabditis elegans from oxidative stress via DAF-16 and TRXR-1.
Q58568596Selenocysteine mimics the effect of dietary restriction on lifespan via SKN‑1 and retards age‑associated pathophysiological changes in Caenorhabditis elegans
Q41597017Should I stay or should I go? Identification of novel nutritionally regulated developmental checkpoints in C. elegans
Q92444736Signaling Network of Forkhead Family of Transcription Factors (FOXO) in Dietary Restriction
Q38358191Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans
Q34938909Sphingolipid metabolism regulates development and lifespan in Caenorhabditis elegans
Q42850763Spontaneous age-related neurite branching in Caenorhabditis elegans
Q79260693Stay Mellow, Stay Young
Q24792967Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16
Q30495978Stimulation of movement in a quiescent, hibernation-like form of Caenorhabditis elegans by dopamine signaling
Q30519466Stress and aging induce distinct polyQ protein aggregation states
Q45906801Stress response of Caenorhabditis elegans induced by space crowding in a micro-column array chip.
Q36428195Stress response pathways protect germ cells from omega-6 polyunsaturated fatty acid-mediated toxicity in Caenorhabditis elegans
Q28303730Stressing the role of FoxO proteins in lifespan and disease
Q34478332Studies of Caenorhabditis elegans DAF-2/insulin signaling reveal targets for pharmacological manipulation of lifespan
Q34068299Systemic and cell intrinsic roles of Gqalpha signaling in the regulation of innate immunity, oxidative stress, and longevity in Caenorhabditis elegans
Q27318316TATN-1 mutations reveal a novel role for tyrosine as a metabolic signal that influences developmental decisions and longevity in Caenorhabditis elegans
Q27332459TDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegans
Q35588365Tasco(®), a product of Ascophyllum nodosum, imparts thermal stress tolerance in Caenorhabditis elegans
Q43175674Temporal requirements of heat shock factor-1 for longevity assurance
Q41769831Temporal requirements of insulin/IGF-1 signaling for proteotoxicity protection
Q38864910The Battle of the Sexes: Human Sex Development and Its Disorders
Q38515423The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling
Q36727248The Caenorhabditis elegans K10C2.4 gene encodes a member of the fumarylacetoacetate hydrolase family: a Caenorhabditis elegans model of type I tyrosinemia
Q27316318The Caenorhabditis elegans Myc-Mondo/Mad complexes integrate diverse longevity signals
Q27332405The DAF-16/FOXO transcription factor functions as a regulator of epidermal innate immunity
Q37071632The DAF-2 insulin-like signaling pathway independently regulates aging and immunity in C. elegans
Q28275268The FoxO code
Q34524678The GATA transcription factor egl-27 delays aging by promoting stress resistance in Caenorhabditis elegans
Q39100343The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner
Q33487151The HIF-1 hypoxia-inducible factor modulates lifespan in C. elegans
Q43223569The Lifespan-Promoting Effect of Otophylloside B in Caenorhabditis elegans
Q27311649The MDT-15 subunit of mediator interacts with dietary restriction to modulate longevity and fluoranthene toxicity in Caenorhabditis elegans
Q38723242The R148.3 Gene Modulates Caenorhabditis elegans Lifespan and Fat Metabolism
Q92881718The Roles of FoxO Transcription Factors in Regulation of Bone Cells Function
Q41628961The SKN-1/Nrf2 transcription factor can protect against oxidative stress and increase lifespan in C. elegans by distinct mechanisms
Q39081371The Sleep in Caenorhabditis elegans: What We Know Until Now.
Q64076738The Stress-Chip: A microfluidic platform for stress analysis in Caenorhabditis elegans
Q37041325The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging.
Q33606931The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover
Q33945331The adiponectin receptor homologs in C. elegans promote energy utilization and homeostasis
Q28489013The alkaloid compound harmane increases the lifespan of Caenorhabditis elegans during bacterial infection, by modulating the nematode's innate immune response
Q41937140The conserved Mediator subunit MDT-15 is required for oxidative stress responses in Caenorhabditis elegans
Q37643958The conserved PBAF nucleosome-remodeling complex mediates the response to stress in Caenorhabditis elegans
Q92966193The flight response impairs cytoprotective mechanisms by activating the insulin pathway
Q39958777The forkhead transcription factor FOXO3a increases phosphoinositide-3 kinase/Akt activity in drug-resistant leukemic cells through induction of PIK3CA expression
Q41881558The garlic constituent diallyl trisulfide increases the lifespan of C. elegans via skn-1 activation
Q39090716The genetics of isoflurane-induced developmental neurotoxicity.
Q35684376The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation
Q37218280The insulin paradox: aging, proteotoxicity and neurodegeneration
Q27335277The interplay between protein L-isoaspartyl methyltransferase activity and insulin-like signaling to extend lifespan in Caenorhabditis elegans
Q37179904The longevity effect of cranberry extract in Caenorhabditis elegans is modulated by daf-16 and osr-1
Q35079447The many forks in FOXO's road
Q37691144The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans
Q24298020The notch regulator MAML1 interacts with p53 and functions as a coactivator
Q34998152The novel hydroxylamine derivative NG-094 suppresses polyglutamine protein toxicity in Caenorhabditis elegans
Q39964082The p38 MAPK PMK-1 shows heat-induced nuclear translocation, supports chaperone expression, and affects the heat tolerance of Caenorhabditis elegans
Q35105986The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor.
Q33804604The protein kinase MBK-1 contributes to lifespan extension in daf-2 mutant and germline-deficient Caenorhabditis elegans
Q36481541The quest for genetic determinants of human longevity: challenges and insights
Q28083445The role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogaster
Q36310130The role of stress in ageing: research on the nematode, Caenorhabditis elegans
Q37048390The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex
Q42460741The von Hippel Lindau tumor suppressor limits longevity
Q36277196Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans
Q46366442Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan
Q36972178To grow or not to grow: nutritional control of development during Caenorhabditis elegans L1 arrest
Q34084120Transcriptional feedback control of insulin receptor by dFOXO/FOXO1.
Q52102444Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16.
Q33617037Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan.
Q45116957Transcriptional targets of DAF-16 insulin signaling pathway protect C. elegans from extreme hypertonic stress
Q42264027Transgenerational Diapause as an Avoidance Strategy against Bacterial Pathogens in Caenorhabditis elegans
Q91994955Treatment of Caenorhabditis elegans with Small Selenium Species Enhances Antioxidant Defense Systems
Q27315422Two membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signaling
Q28536745UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin
Q37219535Ultraviolet-A triggers photoaging in model nematode Caenorhabditis elegans in a DAF-16 dependent pathway.
Q37515518Understanding the molecular basis of Alzheimer's disease using a Caenorhabditis elegans model system
Q89863572Unexpected cell type-dependent effects of autophagy on polyglutamine aggregation revealed by natural genetic variation in C. elegans
Q28680754Unexpected role for dosage compensation in the control of dauer arrest, insulin-like signaling, and FoxO transcription factor activity in Caenorhabditis elegans
Q38253642Use of Caenorhabditis elegans as a model to study Alzheimer's disease and other neurodegenerative diseases
Q34542345Using Caenorhabditis elegans as a model for aging and age-related diseases
Q26776271Using measures of single-cell physiology and physiological state to understand organismic aging
Q36460071Utility of an improved model of amyloid-beta (Aβ₁₋₄₂) toxicity in Caenorhabditis elegans for drug screening for Alzheimer's disease
Q42018471Validated Liquid Culture Monitoring System for Lifespan Extension of Caenorhabditis elegans through Genetic and Dietary Manipulations
Q46772888Valproic acid extends Caenorhabditis elegans lifespan.
Q33886588Variable pathogenicity determines individual lifespan in Caenorhabditis elegans
Q38681055XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity
Q52736080[Aging and the control of the insulin-FOXO signaling pathway].
Q39895267daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway
Q27312521daf-31 encodes the catalytic subunit of N alpha-acetyltransferase that regulates Caenorhabditis elegans development, metabolism and adult lifespan
Q37379074l-Arginine Enhances Resistance against Oxidative Stress and Heat Stress in Caenorhabditis elegans
Q27315174p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans
Q47068710pkc-1 regulates daf-2 insulin/IGF signalling-dependent control of dauer formation in Caenorhabditis elegans

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