scholarly article | Q13442814 |
P50 | author | Thomas Johnson | Q42883774 |
P2093 | author name string | S T Henderson | |
P2860 | cites work | Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor | Q22009126 |
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A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans | Q24603590 | ||
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The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans | Q28131830 | ||
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A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans | Q29617059 | ||
The genetics of caloric restriction in Caenorhabditis elegans | Q29617240 | ||
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling | Q29619762 | ||
Gerontogenes mediate health and longevity in nematodes through increasing resistance to environmental toxins and stressors | Q34071487 | ||
Genetic analysis of life-span in Caenorhabditis elegans | Q36318911 | ||
Mechanisms and evolution of aging | Q41003075 | ||
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Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence | Q42472986 | ||
Extension of Life-Span with Superoxide Dismutase/Catalase Mimetics | Q62472542 | ||
Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging | Q63951809 | ||
Adaptation to oxidative stress in young, but not in mature or old, Caenorhabditis elegans | Q72222026 | ||
P433 | issue | 24 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Caenorhabditis elegans | Q91703 |
Forkhead box protein O CELE_R13H8.1 | Q29795009 | ||
P304 | page(s) | 1975-1980 | |
P577 | publication date | 2001-12-01 | |
P1433 | published in | Current Biology | Q1144851 |
P1476 | title | daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans | |
P478 | volume | 11 |
Q38656428 | "High-Throughput Characterization of Region-Specific Mitochondrial Function and Morphology". |
Q38683789 | 1,4-Naphthoquinone Triggers Nematode Lethality by Inducing Oxidative Stress and Activating Insulin/IGF Signaling Pathway in Caenorhabditis elegans |
Q36941366 | 25 years after age-1: genes, interventions and the revolution in aging research |
Q50428448 | A 44 bp intestine-specific hermaphrodite-specific enhancer from the C. elegans vit-2 vitellogenin gene is directly regulated by ELT-2, MAB-3, FKH-9 and DAF-16 and indirectly regulated by the germline, by daf-2/insulin signaling and by the TGF-β/Sma/ |
Q37690533 | A Caenorhabditis elegans developmental decision requires insulin signaling-mediated neuron-intestine communication |
Q52631468 | A Caenorhabditis elegans insulin-like peptide, INS-17: its physiological function and expression pattern. |
Q46983064 | A DAF-16/FoxO3a-dependent longevity signal is initiated by antioxidants |
Q91769925 | A Memory Circuit for Coping with Impending Adversity |
Q90029553 | A New Tool for Inducible Gene Expression in Caenorhabditis elegans |
Q37253833 | A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation |
Q42621207 | A Proteomic Analysis Provides Novel Insights into the Stress Responses of Caenorhabditis elegans towards Nematicidal Cry6A Toxin from Bacillus thuringiensis |
Q30482188 | A carbon dioxide avoidance behavior is integrated with responses to ambient oxygen and food in Caenorhabditis elegans |
Q43022319 | A circulatory transcriptional regulation among daf-9, daf-12, and daf-16 mediates larval development upon cholesterol starvation in Caenorhabditis elegans |
Q34042717 | A conserved PHD finger protein and endogenous RNAi modulate insulin signaling in Caenorhabditis elegans |
Q41243930 | A conserved neuronal DAF-16/FoxO plays an important role in conveying pheromone signals to elicit repulsion behavior in Caenorhabditis elegans |
Q27305176 | A directed RNAi screen based on larval growth arrest reveals new modifiers of C. elegans insulin signaling |
Q41311496 | A genetic program promotes C. elegans longevity at cold temperatures via a thermosensitive TRP channel |
Q28817531 | A genome-wide screen of bacterial mutants that enhance dauer formation in C. elegans |
Q44550168 | A metabolic model for life span determination in Caenorhabditis elegans |
Q90435755 | A metabolic switch regulates the transition between growth and diapause in C. elegans |
Q91151413 | A microfluidic-induced C. elegans sleep state |
Q46962604 | A neuronal GPCR is critical for the induction of the heat shock response in the nematode C. elegans. |
Q35030335 | A new DAF-16 isoform regulates longevity. |
Q34675252 | A novel mitochondrial outer membrane protein, MOMA-1, that affects cristae morphology in Caenorhabditis elegans |
Q33374003 | A novel role for the SMG-1 kinase in lifespan and oxidative stress resistance in Caenorhabditis elegans |
Q37782380 | A pathway that links reproductive status to lifespan in Caenorhabditis elegans |
Q41161982 | A peroxiredoxin, PRDX-2, is required for insulin secretion and insulin/IIS-dependent regulation of stress resistance and longevity |
Q54595214 | A polymorphism of the YTHDF2 gene (1p35) located in an Alu-rich genomic domain is associated with human longevity. |
Q37075953 | A sleep state during C. elegans development |
Q27349187 | A transcription elongation factor that links signals from the reproductive system to lifespan extension in Caenorhabditis elegans |
Q63874606 | A universal transcriptomic signature of age reveals the temporal scaling of Caenorhabditis elegans aging trajectories. |
Q36028971 | APL-1, the Alzheimer's Amyloid precursor protein in Caenorhabditis elegans, modulates multiple metabolic pathways throughout development |
Q27317086 | ASM-3 acid sphingomyelinase functions as a positive regulator of the DAF-2/AGE-1 signaling pathway and serves as a novel anti-aging target |
Q40471141 | Acacetin 7-O-α-l-rhamnopyranosyl (1-2) β-D-xylopyranoside Elicits Life-span Extension and Stress Resistance in Caenorhabditis elegans. |
Q33259341 | Activated AKT/PKB signaling in C. elegans uncouples temporally distinct outputs of DAF-2/insulin-like signaling |
Q34229357 | Activated and inactivated immune responses in Caenorhabditis elegans against Photorhabdus luminescens TT01 |
Q51764520 | Activation of DAF-16/FOXO by reactive oxygen species contributes to longevity in long-lived mitochondrial mutants in Caenorhabditis elegans. |
Q24630961 | Aging as an event of proteostasis collapse |
Q41894661 | Aging causes decreased resistance to multiple stresses and a failure to activate specific stress response pathways |
Q48942620 | Aging-dependent and -independent modulation of associative learning behavior by insulin/insulin-like growth factor-1 signal in Caenorhabditis elegans. |
Q35013461 | Altered bacterial metabolism, not coenzyme Q content, is responsible for the lifespan extension in Caenorhabditis elegans fed an Escherichia coli diet lacking coenzyme Q. |
Q36661626 | Aluminium exposure disrupts elemental homeostasis in Caenorhabditis elegans |
Q41834228 | An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans |
Q42018178 | An age-dependent reversal in the protective capacities of JNK signaling shortens Caenorhabditis elegans lifespan |
Q46459137 | An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans |
Q102054635 | An integrated microfluidics for assessing the anti-aging effect of caffeic acid phenethylester in Caenorhabditis elegans |
Q33214158 | Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression |
Q38747871 | Angiostrongylus cantonensis daf-2 regulates dauer, longevity and stress in Caenorhabditis elegans |
Q36044909 | Antioxidative Activities of Both Oleic Acid and Camellia tenuifolia Seed Oil Are Regulated by the Transcription Factor DAF-16/FOXO in Caenorhabditis elegans |
Q42185376 | Antipsychotic drugs activate the C. elegans akt pathway via the DAF-2 insulin/IGF-1 receptor |
Q42963853 | Apigenin inhibits larval growth of Caenorhabditis elegans through DAF-16 activation |
Q64982096 | Apoptosis contributes to protect germ cells from the oogenic germline starvation response but is not essential for the gonad shrinking or recovery observed during adult reproductive diapause in C. elegans. |
Q49697484 | Arbutin increases Caenorhabditis elegans longevity and stress resistance. |
Q33832471 | Arrestin and the multi-PDZ domain-containing protein MPZ-1 interact with phosphatase and tensin homolog (PTEN) and regulate Caenorhabditis elegans longevity |
Q39406636 | Assessing Health Span in Caenorhabditis elegans: Lessons From Short-Lived Mutants |
Q37318302 | Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance |
Q34999318 | Behavioral and metabolic effects of the atypical antipsychotic ziprasidone on the nematode Caenorhabditis elegans |
Q26777407 | Biochemical Genetic Pathways that Modulate Aging in Multiple Species |
Q48465401 | Both insulin and calcium channel signaling are required for developmental regulation of serotonin synthesis in the chemosensory ADF neurons of Caenorhabditis elegans. |
Q51766615 | Brain-gut communications via distinct neuroendocrine signals bidirectionally regulate longevity in C. elegans. |
Q37173143 | Burkholderia pseudomallei suppresses Caenorhabditis elegans immunity by specific degradation of a GATA transcription factor |
Q24324828 | C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span |
Q47068907 | C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span |
Q27308714 | C. elegans VANG-1 modulates life span via insulin/IGF-1-like signaling |
Q37245616 | C. elegans dauer formation and the molecular basis of plasticity |
Q36952338 | CAMKII and calcineurin regulate the lifespan of Caenorhabditis elegans through the FOXO transcription factor DAF-16. |
Q90411124 | Caenorhabditis Sieve: A Low-tech Instrument and Methodology for Sorting Small Multicellular Organisms |
Q26781364 | Caenorhabditis elegans DAF-16/FOXO transcription factor and its mammalian homologs associate with age-related disease |
Q36597116 | Caenorhabditis elegans EAK-3 inhibits dauer arrest via nonautonomous regulation of nuclear DAF-16/FoxO activity |
Q50208902 | Caenorhabditis elegans Genes Affecting Interindividual Variation in Life-span Biomarker Gene Expression. |
Q35907679 | Caenorhabditis elegans Heterochromatin protein 1 (HPL-2) links developmental plasticity, longevity and lipid metabolism |
Q34644668 | Caenorhabditis elegans OSR-1 regulates behavioral and physiological responses to hyperosmotic environments |
Q36829284 | Caenorhabditis elegans as a model system to study aging of learning and memory |
Q55003096 | Caenorhabditis elegans susceptibility to Daldinia cf. concentrica bioactive volatiles is coupled with expression activation of the stress-response transcription factor daf-16, a part of distinct nematicidal action. |
Q34569825 | Caloric restriction and intermittent fasting: two potential diets for successful brain aging |
Q33903791 | Cancer models in Caenorhabditis elegans |
Q27349803 | Candida albicans infection of Caenorhabditis elegans induces antifungal immune defenses |
Q39626703 | Carlina acaulis Exhibits Antioxidant Activity and Counteracts Aβ Toxicity in Caenorhabditis elegans |
Q92156064 | Carnosol Improved Lifespan and Healthspan by Promoting Antioxidant Capacity in Caenorhabditis elegans |
Q34981283 | Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity |
Q39042190 | Cell Biology of the Caenorhabditis elegans Nucleus |
Q28646130 | Cell cycle and death control: long live Forkheads |
Q27308063 | Cell-Autonomous and Non-Cell-Autonomous Regulation of a Feeding State-Dependent Chemoreceptor Gene via MEF-2 and bHLH Transcription Factors |
Q64259123 | Cell-autonomous and non-autonomous roles of in muscle function and mitochondrial capacity in aging |
Q27332314 | Cell-nonautonomous signaling of FOXO/DAF-16 to the stem cells of Caenorhabditis elegans |
Q88955687 | Cellular and epigenetic drivers of stem cell ageing |
Q97634549 | Changes in ferrous iron and glutathione promote ferroptosis and frailty in aging Caenorhabditis elegans |
Q41867742 | Checkpoint proteins control survival of the postmitotic cells in Caenorhabditis elegans |
Q51663636 | Chlorogenic Acid Extends the Lifespan of Caenorhabditis elegans via Insulin/IGF-1 Signaling Pathway. |
Q40124271 | Chlorophyll enhances oxidative stress tolerance in Caenorhabditis elegans and extends its lifespan |
Q37189473 | Chromatin immunoprecipitation (ChIP) coupled to detection by quantitative real-time PCR to study transcription factor binding to DNA in Caenorhabditis elegans. |
Q33533754 | Cinnamomum cassia bark in two herbal formulas increases life span in Caenorhabditis elegans via insulin signaling and stress response pathways |
Q36470497 | Clustering of genetically defined allele classes in the Caenorhabditis elegans DAF-2 insulin/IGF-1 receptor |
Q24643933 | Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging |
Q33582514 | Combined informatic and expression screen identifies the novel DAF-16 target HLH-13 |
Q50177107 | Comparison of physiological functions of antagonistic insulin-like peptides, INS-23 and INS-18, in Caenorhabditis elegans. |
Q34356248 | Conditioning protects C. elegans from lethal effects of enteropathogenic E. coli by activating genes that regulate lifespan and innate immunity |
Q27313826 | Coordinated regulation of intestinal functions in C. elegans by LIN-35/Rb and SLR-2 |
Q36171595 | Counting the calories: the role of specific nutrients in extension of life span by food restriction |
Q90243921 | DAF-16 and SMK-1 Contribute to Innate Immunity During Adulthood in Caenorhabditis elegans |
Q34023656 | DAF-16 and Δ9 desaturase genes promote cold tolerance in long-lived Caenorhabditis elegans age-1 mutants |
Q37109335 | DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity |
Q35182652 | DAF-16 target identification in C. elegans: past, present and future |
Q36470586 | DAF-16-dependent suppression of immunity during reproduction in Caenorhabditis elegans |
Q42140945 | DAF-16/FOXO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage |
Q57798855 | DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity |
Q92021484 | DAF-16/FOXO promotes taste avoidance learning independently of axonal insulin-like signaling |
Q41776463 | DAF-16/FOXO regulates homeostasis of essential sleep-like behavior during larval transitions in C. elegans |
Q92527353 | DAF-16/FOXO requires Protein Phosphatase 4 to initiate transcription of stress resistance and longevity promoting genes |
Q42572335 | DAF-16/Forkhead box O transcription factor: many paths to a single Fork(head) in the road |
Q27317096 | DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans |
Q33307539 | DAF-2/insulin-like signaling in C. elegans modifies effects of dietary restriction and nutrient stress on aging, stress and growth |
Q58786850 | DAF-21/Hsp90 is required for C. elegans longevity by ensuring DAF-16/FOXO isoform A function |
Q68471390 | DAF‐16 stabilizes the aging transcriptome and is activated in mid‐aged Caenorhabditis elegans to cope with internal stress |
Q34175789 | DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO |
Q30625412 | Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity |
Q35139549 | Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty |
Q47321608 | Demonstrating Improved Multiple Transport-Mean-Free-Path Imaging Capabilities of Light Sheet Microscopy in the Quantification of Fluorescence Dynamics. |
Q38003249 | Developmental decisions: balancing genetics and the environment by C. elegans |
Q41199961 | Dianxianning improved amyloid β-induced pathological characteristics partially through DAF-2/DAF-16 insulin like pathway in transgenic C. elegans |
Q34539839 | Diapause formation and downregulation of insulin-like signaling via DAF-16/FOXO delays axonal degeneration and neuronal loss |
Q61818318 | Diapause induces functional axonal regeneration after necrotic insult in C. elegans |
Q36267854 | Dietary restriction in the nematode Caenorhabditis elegans |
Q36075067 | Dietary restriction, mitochondrial function and aging: from yeast to humans |
Q37187457 | Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans |
Q37671736 | Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: roles for GATA factors and lipid gene regulators |
Q29619580 | Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans |
Q33618405 | Disruption of insulin signalling preserves bioenergetic competence of mitochondria in ageing Caenorhabditis elegans |
Q35065169 | Disruption of the ATP-binding cassette B7 (ABTM-1/ABCB7) induces oxidative stress and premature cell death in Caenorhabditis elegans |
Q30506041 | Dissection of the NUP107 nuclear pore subcomplex reveals a novel interaction with spindle assembly checkpoint protein MAD1 in Caenorhabditis elegans |
Q36391893 | Distinct activities of the germline and somatic reproductive tissues in the regulation of Caenorhabditis elegans' longevity |
Q38606885 | Distinct unfolded protein responses mitigate or mediate effects of nonlethal deprivation of C. elegans sleep in different tissues |
Q27335163 | Divergent mechanisms controlling hypoxic sensitivity and lifespan by the DAF-2/insulin/IGF-receptor pathway |
Q38177357 | Drug discovery based on genetic and metabolic findings in schizophrenia |
Q30823235 | Durable spatiotemporal surveillance of Caenorhabditis elegans response to environmental cues |
Q33842100 | Dynamic O-GlcNAc cycling at promoters of Caenorhabditis elegans genes regulating longevity, stress, and immunity |
Q90381677 | Dysregulation of DAF-16/FOXO3A-mediated stress responses accelerates oxidative DNA damage induced aging |
Q34361259 | EAK proteins: novel conserved regulators of C. elegans lifespan |
Q34011075 | EAK-7 controls development and life span by regulating nuclear DAF-16/FoxO activity |
Q27346260 | ETS-4 is a transcriptional regulator of life span in Caenorhabditis elegans |
Q37298076 | Effects of Caenorhabditis elegans sgk-1 mutations on lifespan, stress resistance, and DAF-16/FoxO regulation |
Q51941271 | Effects of a Caenorhabditis elegans dauer pheromone ascaroside on physiology and signal transduction pathways. |
Q47918372 | Emodin extends lifespan of Caenorhabditis elegans through insulin/IGF-1 signaling pathway depending on DAF-16 and SIR-2.1. |
Q34005604 | Endocrine regulation of ageing |
Q36379602 | Endocrine targets for pharmacological intervention in aging in Caenorhabditis elegans |
Q35212089 | Endogenous ROS levels in C. elegans under exogenous stress support revision of oxidative stress theory of life-history tradeoffs |
Q60922133 | Enhancing GABAergic Transmission Improves Locomotion in a Model of Spinal Muscular Atrophy |
Q58777893 | Enhancing and Extending Biological Performance and Resilience |
Q30666205 | Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression |
Q27339190 | Exercise in an electrotactic flow chamber ameliorates age-related degeneration in Caenorhabditis elegans. |
Q37271606 | Expression of ceramide glucosyltransferases, which are essential for glycosphingolipid synthesis, is only required in a small subset of C. elegans cells |
Q27333224 | Extension of lifespan in C. elegans by naphthoquinones that act through stress hormesis mechanisms |
Q47129995 | FOXO Transcriptional Factors and Long-Term Living |
Q36429676 | FOXO factors: a matter of life and death |
Q28588727 | FOXO forkhead transcription factors induce G(2)-M checkpoint in response to oxidative stress |
Q40493379 | FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK. |
Q29620472 | FOXO transcription factors at the interface between longevity and tumor suppression |
Q37337795 | FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis. |
Q40863378 | Fast, sensitive discovery of conserved genome-wide motifs |
Q93075111 | Fasting prevents hypoxia-induced defects of proteostasis in C. elegans |
Q55554499 | Fitness Trade-Offs and Environmentally Induced Mutation Buffering in Isogenic C. elegans |
Q57293500 | Food perception without ingestion leads to metabolic changes and irreversible developmental arrest in C. elegans |
Q46955933 | FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression |
Q28590430 | FoxO6 regulates memory consolidation and synaptic function |
Q35860602 | Freeze-thaw Caenorhabditis elegans freeze-thaw stress response is regulated by the insulin/IGF-1 receptor daf-2. |
Q33321969 | Function of the PHA-4/FOXA transcription factor during C. elegans post-embryonic development |
Q35879827 | Functional divergence of dafachronic acid pathways in the control of C. elegans development and lifespan |
Q59125605 | G2019S LRRK2 Increases Stress Susceptibility Through Inhibition of DAF-16 Nuclear Translocation in a 14-3-3 Associated-Manner in Caenorhabditis elegans |
Q26749187 | GATA transcription factors as tissue-specific master regulators for induced responses |
Q64883552 | Gastrodin protects dopaminergic neurons via insulin-like pathway in a Parkinson's disease model. |
Q36508693 | Genetic analysis of hyl-1, the C. elegans homolog of LAG1/LASS1. |
Q60922376 | Genetic and pharmacological interventions in the aging motor nervous system slow motor aging and extend life span in |
Q36280473 | Genetic approaches to study aging in Drosophila melanogaster |
Q37340771 | Genetic basis of neurocognitive decline and reduced white-matter integrity in normal human brain aging |
Q28748529 | Genetic mechanisms of coffee extract protection in a Caenorhabditis elegans model of β-amyloid peptide toxicity |
Q28469314 | Genetics of aging in Caenorhabditis elegans |
Q36561507 | Genome-wide endogenous DAF-16/FOXO recruitment dynamics during lowered insulin signalling in C. elegans |
Q33918911 | Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression |
Q36083338 | Gravity force transduced by the MEC-4/MEC-10 DEG/ENaC channel modulates DAF-16/FoxO activity in Caenorhabditis elegans |
Q36334971 | Green Tea Extract Induces the Resistance of Caenorhabditis elegans against Oxidative Stress |
Q38545032 | H2S: A New Approach to Lifespan Enhancement and Healthy Ageing? |
Q37693738 | HIF-1 modulates longevity and healthspan in a temperature-dependent manner |
Q35016513 | Heat-shock transcription factor (HSF)-1 pathway required for Caenorhabditis elegans immunity |
Q34753563 | Homeostasis in C. elegans sleep is characterized by two behaviorally and genetically distinct mechanisms |
Q50272457 | Hormonal components of altered developmental pathways in the annual killifish, Austrofundulus limnaeus. |
Q42132873 | Host translational inhibition by Pseudomonas aeruginosa Exotoxin A Triggers an immune response in Caenorhabditis elegans |
Q47069404 | Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation |
Q27315079 | Identification of late larval stage developmental checkpoints in Caenorhabditis elegans regulated by insulin/IGF and steroid hormone signaling pathways |
Q37188636 | Increased age reduces DAF-16 and SKN-1 signaling and the hormetic response of Caenorhabditis elegans to the xenobiotic juglone |
Q36851630 | Influence of steroid hormone signaling on life span control by Caenorhabditis elegans insulin-like signaling |
Q64259170 | Ingredients in Zijuan Pu'er Tea Extract Alleviate β-Amyloid Peptide Toxicity in a Model of Alzheimer's Disease Likely through DAF-16 |
Q35582500 | Insulin and JNK: optimizing metabolic homeostasis and lifespan |
Q36488671 | Insulin signaling in Caenorhabditis elegans regulates both endocrine-like and cell-autonomous outputs |
Q33684279 | Insulin signaling promotes germline proliferation in C. elegans |
Q46627365 | Insulin-like signaling negatively regulates muscle arm extension through DAF-12 in Caenorhabditis elegans |
Q27334849 | Insulin/IGF-1 and hypoxia signaling act in concert to regulate iron homeostasis in Caenorhabditis elegans |
Q64076625 | Insulin/IGF-1R, SIRT1, and FOXOs Pathways-An Intriguing Interaction Platform for Bone and Osteosarcoma |
Q35554316 | Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans |
Q37585122 | Insulin/IGF1 signaling inhibits age-dependent axon regeneration |
Q28305190 | Integrating the stress response: lessons for neurodegenerative diseases from C. elegans |
Q37262814 | Integration of diverse inputs in the regulation of Caenorhabditis elegans DAF-16/FOXO. |
Q28507004 | Integration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity |
Q44412850 | Intermittent fasting and dietary supplementation with 2‐deoxy‐D‐glucose improve functional and metabolic cardiovascular risk factors in rats |
Q34361218 | Intracellular protein glycosylation modulates insulin mediated lifespan in C.elegans |
Q28386928 | Involvement of the up-regulated FoxO1 expression in follicular granulosa cell apoptosis induced by oxidative stress |
Q41949373 | Isotopic ratio outlier analysis global metabolomics of Caenorhabditis elegans |
Q33934548 | JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16. |
Q34765402 | Juvenile hormone and insulin regulate trehalose homeostasis in the red flour beetle, Tribolium castaneum. |
Q46704659 | LET-60 RAS modulates effects of insulin/IGF-1 signaling on development and aging in Caenorhabditis elegans |
Q37189208 | Life-span extension from hypoxia in Caenorhabditis elegans requires both HIF-1 and DAF-16 and is antagonized by SKN-1 |
Q52039780 | Lifespan and dauer regulation by tissue-specific activities of Caenorhabditis elegans DAF-18. |
Q27324080 | Lifespan-extending effects of royal jelly and its related substances on the nematode Caenorhabditis elegans |
Q38673046 | Lifespan-regulating genes in C. elegans |
Q33942347 | Light and pheromone-sensing neurons regulates cold habituation through insulin signalling in Caenorhabditis elegans |
Q35970467 | Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence |
Q26773901 | Long live FOXO: unraveling the role of FOXO proteins in aging and longevity |
Q25255758 | Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent translocation of DAF-16/FOXO to the cytoplasm |
Q33863373 | Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands |
Q36132307 | Longevity Genes Revealed by Integrative Analysis of Isoform-Specific daf-16/FoxO Mutants of Caenorhabditis elegans |
Q35078356 | Longevity and heat stress regulation in Caenorhabditis elegans |
Q33315298 | Longevity and resistance to stress correlate with DNA repair capacity in Caenorhabditis elegans |
Q35254761 | Longevity and stress in Caenorhabditis elegans |
Q34757207 | Longevity genes in the nematode Caenorhabditis elegans also mediate increased resistance to stress and prevent disease. |
Q92028301 | Longevity: Lesson from Model Organisms |
Q27301833 | Loss of C. elegans GON-1, an ADAMTS9 Homolog, Decreases Secretion Resulting in Altered Lifespan and Dauer Formation |
Q54967620 | Lowbush cranberry acts through DAF-16/FOXO signaling to promote increased lifespan and axon branching in aging posterior touch receptor neurons. |
Q54978541 | MPK-1/ERK pathway regulates DNA damage response during development through DAF-16/FOXO. |
Q28246430 | Mammalian SIRT1 represses forkhead transcription factors |
Q28077338 | Mechanisms of aging-related proteinopathies in Caenorhabditis elegans |
Q87981906 | Metabolic shift from glycogen to trehalose promotes lifespan and healthspan in Caenorhabditis elegans |
Q89012051 | Methyl 3,4-Dihydroxybenzoate Enhances Resistance to Oxidative Stressors and Lifespan in C. elegans Partially via daf-2/daf-16 |
Q36209138 | Methylation by Set9 modulates FoxO3 stability and transcriptional activity. |
Q93217116 | MiDaf16-like and MiSkn1-like gene families are reliable targets to develop biotechnological tools for the control and management of Meloidogyne incognita |
Q41882618 | MicroRNA mir-34 provides robustness to environmental stress response via the DAF-16 network in C. elegans |
Q36955062 | MicroRNAs and the genetic network in aging. |
Q40139530 | Mitochondrial dysfunction, oxidative stress, and neurodegeneration elicited by a bacterial metabolite in a C. elegans Parkinson's model |
Q27314783 | Mitochondrial function is required for secretion of DAF-28/insulin in C. elegans |
Q34767374 | Mitochondrial longevity pathways |
Q60044019 | Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways |
Q28255998 | Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa |
Q36315295 | Modulation of Caenorhabditis elegans infection sensitivity by the LIN-7 cell junction protein |
Q89266567 | Modulation of caveolae by insulin/IGF-1 signaling regulates aging of Caenorhabditis elegans |
Q50187389 | Modulatory upregulation of an insulin peptide gene by different pathogens in C. elegans. |
Q33891308 | Molecular characterization of numr-1 and numr-2: genes that increase both resistance to metal-induced stress and lifespan in Caenorhabditis elegans |
Q37245881 | Molecular cloning and DNA binding characterization of DAF-16 orthologs from Ancylostoma hookworms. |
Q36829270 | Molecular signaling involved in regulating feeding and other motivated behaviors |
Q34321472 | Monascus-fermented dioscorea enhances oxidative stress resistance via DAF-16/FOXO in Caenorhabditis elegans |
Q37585797 | NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans |
Q37137329 | NSBP-1 mediates the effects of cholesterol on insulin/IGF-1 signaling in Caenorhabditis elegans. |
Q100415730 | NemaLife chip: a micropillar-based microfluidic culture device optimized for aging studies in crawling C. elegans |
Q42443115 | Neuroendocrine signals modulate the innate immunity of Caenorhabditis elegans through insulin signaling |
Q37279423 | Neuronal ROS signaling rather than AMPK/sirtuin-mediated energy sensing links dietary restriction to lifespan extension |
Q35650853 | Neuronal and molecular substrates for optimal foraging in Caenorhabditis elegans |
Q35125807 | New genes that extend Caenorhabditis elegans' lifespan in response to reproductive signals |
Q91915881 | New label-free automated survival assays reveal unexpected stress resistance patterns during C. elegans aging |
Q37581650 | Non-linear impact of glutathione depletion on C. elegans life span and stress resistance |
Q36109887 | Non-transcriptional Function of FOXO1/DAF-16 Contributes to Translesion DNA Synthesis |
Q42693068 | Nonautonomous regulation of neuronal migration by insulin signaling, DAF-16/FOXO, and PAK-1 |
Q27349004 | Nucleolar proteins suppress Caenorhabditis elegans innate immunity by inhibiting p53/CEP-1 |
Q24288717 | OASIS: online application for the survival analysis of lifespan assays performed in aging research |
Q46430310 | Octopamine enhances oxidative stress resistance through the fasting-responsive transcription factor DAF-16/FOXO in C. elegans |
Q47097416 | Omics Approaches for Identifying Physiological Adaptations to Genome Instability in Aging |
Q55432540 | Opposing roles of microRNA Argonautes during Caenorhabditis elegans aging. |
Q90727479 | Overcoming Autofluorescence to Assess GFP Expression During Normal Physiology and Aging in Caenorhabditis elegans |
Q37387918 | Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1. |
Q27342393 | PDP-1 links the TGF-β and IIS pathways to regulate longevity, development, and metabolism |
Q44731575 | PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans |
Q42585902 | PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity |
Q36974448 | Pan-neuronal expression of APL-1, an APP-related protein, disrupts olfactory, gustatory, and touch plasticity in Caenorhabditis elegans |
Q93051373 | Pervasive Positive and Negative Feedback Regulation of Insulin-Like Signaling in Caenorhabditis elegans |
Q37337188 | Pharmacogenetic analysis of lithium-induced delayed aging in Caenorhabditis elegans |
Q36553629 | Pharmacological lifespan extension of invertebrates |
Q33549702 | Phenotypic covariance of longevity, immunity and stress resistance in the caenorhabditis nematodes |
Q38071570 | Physiological functions of protein kinase D in vivo. |
Q39088167 | Plant-parasitic nematodes: towards understanding molecular players in stress responses |
Q39916580 | Positive and negative feedback regulates the transcription factor FOXL2 in response to cell stress: evidence for a regulatory imbalance induced by disease-causing mutations |
Q27346904 | Prohibitin-mediated lifespan and mitochondrial stress implicate SGK-1, insulin/IGF and mTORC2 in C. elegans |
Q92088136 | Prolonged quiescence delays somatic stem cell-like divisions in Caenorhabditis elegans and is controlled by insulin signaling |
Q39752332 | Properties, regulation, and in vivo functions of a novel protein kinase D: Caenorhabditis elegans DKF-2 links diacylglycerol second messenger to the regulation of stress responses and life span |
Q30489976 | Proteasomal regulation of the hypoxic response modulates aging in C. elegans |
Q36220305 | Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan |
Q27318409 | Pseudomonas aeruginosa suppresses host immunity by activating the DAF-2 insulin-like signaling pathway in Caenorhabditis elegans |
Q36761262 | Public and private mechanisms of life extension in Caenorhabditis elegans |
Q35946175 | RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling in Caenorhabditis elegans |
Q37143073 | RNA helicase SACY-1 is required for longevity caused by various genetic perturbations in Caenorhabditis elegans. |
Q34986923 | RNAi screens to identify components of gene networks that modulate aging in Caenorhabditis elegans |
Q38042425 | ROS in aging Caenorhabditis elegans: damage or signaling? |
Q39103593 | Receptor Guanylyl Cyclases in Sensory Processing. |
Q36543140 | Reconstruction of the insulin-like signalling pathway of Haemonchus contortus |
Q37989767 | Red mold, diabetes, and oxidative stress: a review. |
Q47069491 | Reduced expression of the Caenorhabditis elegans p53 ortholog cep-1 results in increased longevity |
Q29619759 | Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor |
Q35749589 | Regulation of Caenorhabditis elegans lifespan by a proteasomal E3 ligase complex |
Q37467624 | Regulation of DAF-16-mediated Innate Immunity in Caenorhabditis elegans |
Q50897629 | Regulation of Lysosomal Function by the DAF-16 Forkhead Transcription Factor Couples Reproduction to Aging in Caenorhabditis elegans. |
Q36673555 | Regulation of longevity by the reproductive system |
Q36835699 | Regulation of oxidative stress by the anti-aging hormone klotho |
Q33431583 | Regulation of the longevity response to temperature by thermosensory neurons in Caenorhabditis elegans |
Q27334743 | Repression of a potassium channel by nuclear hormone receptor and TGF-β signaling modulates insulin signaling in Caenorhabditis elegans |
Q90261920 | Repurposing bioactive compounds for treating multidrug-resistant pathogens |
Q35527215 | Rifampicin reduces advanced glycation end products and activates DAF-16 to increase lifespan in Caenorhabditis elegans |
Q35010485 | Role of insulin/insulin-like growth factor 1 signaling pathway in longevity. |
Q39481696 | Rosmarinus officinalis L. increases Caenorhabditis elegans stress resistance and longevity in a DAF-16, HSF-1 and SKN-1-dependent manner. |
Q24658178 | SHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegans |
Q39896060 | SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response |
Q39988144 | SKN-1-independent transcriptional activation of glutathione S-transferase 4 (GST-4) by EGF signaling |
Q33690581 | SLR-2 and JMJC-1 regulate an evolutionarily conserved stress-response network |
Q42736661 | Secondary metabolites of Pseudomonas fluorescens CHA0 drive complex non-trophic interactions with bacterivorous nematodes |
Q46969722 | Selenite protects Caenorhabditis elegans from oxidative stress via DAF-16 and TRXR-1. |
Q58568596 | Selenocysteine mimics the effect of dietary restriction on lifespan via SKN‑1 and retards age‑associated pathophysiological changes in Caenorhabditis elegans |
Q41597017 | Should I stay or should I go? Identification of novel nutritionally regulated developmental checkpoints in C. elegans |
Q92444736 | Signaling Network of Forkhead Family of Transcription Factors (FOXO) in Dietary Restriction |
Q38358191 | Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans |
Q34938909 | Sphingolipid metabolism regulates development and lifespan in Caenorhabditis elegans |
Q42850763 | Spontaneous age-related neurite branching in Caenorhabditis elegans |
Q79260693 | Stay Mellow, Stay Young |
Q24792967 | Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16 |
Q30495978 | Stimulation of movement in a quiescent, hibernation-like form of Caenorhabditis elegans by dopamine signaling |
Q30519466 | Stress and aging induce distinct polyQ protein aggregation states |
Q45906801 | Stress response of Caenorhabditis elegans induced by space crowding in a micro-column array chip. |
Q36428195 | Stress response pathways protect germ cells from omega-6 polyunsaturated fatty acid-mediated toxicity in Caenorhabditis elegans |
Q28303730 | Stressing the role of FoxO proteins in lifespan and disease |
Q34478332 | Studies of Caenorhabditis elegans DAF-2/insulin signaling reveal targets for pharmacological manipulation of lifespan |
Q34068299 | Systemic and cell intrinsic roles of Gqalpha signaling in the regulation of innate immunity, oxidative stress, and longevity in Caenorhabditis elegans |
Q27318316 | TATN-1 mutations reveal a novel role for tyrosine as a metabolic signal that influences developmental decisions and longevity in Caenorhabditis elegans |
Q27332459 | TDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegans |
Q35588365 | Tasco(®), a product of Ascophyllum nodosum, imparts thermal stress tolerance in Caenorhabditis elegans |
Q43175674 | Temporal requirements of heat shock factor-1 for longevity assurance |
Q41769831 | Temporal requirements of insulin/IGF-1 signaling for proteotoxicity protection |
Q38864910 | The Battle of the Sexes: Human Sex Development and Its Disorders |
Q38515423 | The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling |
Q36727248 | The Caenorhabditis elegans K10C2.4 gene encodes a member of the fumarylacetoacetate hydrolase family: a Caenorhabditis elegans model of type I tyrosinemia |
Q27316318 | The Caenorhabditis elegans Myc-Mondo/Mad complexes integrate diverse longevity signals |
Q27332405 | The DAF-16/FOXO transcription factor functions as a regulator of epidermal innate immunity |
Q37071632 | The DAF-2 insulin-like signaling pathway independently regulates aging and immunity in C. elegans |
Q28275268 | The FoxO code |
Q34524678 | The GATA transcription factor egl-27 delays aging by promoting stress resistance in Caenorhabditis elegans |
Q39100343 | The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner |
Q33487151 | The HIF-1 hypoxia-inducible factor modulates lifespan in C. elegans |
Q43223569 | The Lifespan-Promoting Effect of Otophylloside B in Caenorhabditis elegans |
Q27311649 | The MDT-15 subunit of mediator interacts with dietary restriction to modulate longevity and fluoranthene toxicity in Caenorhabditis elegans |
Q38723242 | The R148.3 Gene Modulates Caenorhabditis elegans Lifespan and Fat Metabolism |
Q92881718 | The Roles of FoxO Transcription Factors in Regulation of Bone Cells Function |
Q41628961 | The SKN-1/Nrf2 transcription factor can protect against oxidative stress and increase lifespan in C. elegans by distinct mechanisms |
Q39081371 | The Sleep in Caenorhabditis elegans: What We Know Until Now. |
Q64076738 | The Stress-Chip: A microfluidic platform for stress analysis in Caenorhabditis elegans |
Q37041325 | The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging. |
Q33606931 | The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover |
Q33945331 | The adiponectin receptor homologs in C. elegans promote energy utilization and homeostasis |
Q28489013 | The alkaloid compound harmane increases the lifespan of Caenorhabditis elegans during bacterial infection, by modulating the nematode's innate immune response |
Q41937140 | The conserved Mediator subunit MDT-15 is required for oxidative stress responses in Caenorhabditis elegans |
Q37643958 | The conserved PBAF nucleosome-remodeling complex mediates the response to stress in Caenorhabditis elegans |
Q92966193 | The flight response impairs cytoprotective mechanisms by activating the insulin pathway |
Q39958777 | The forkhead transcription factor FOXO3a increases phosphoinositide-3 kinase/Akt activity in drug-resistant leukemic cells through induction of PIK3CA expression |
Q41881558 | The garlic constituent diallyl trisulfide increases the lifespan of C. elegans via skn-1 activation |
Q39090716 | The genetics of isoflurane-induced developmental neurotoxicity. |
Q35684376 | The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation |
Q37218280 | The insulin paradox: aging, proteotoxicity and neurodegeneration |
Q27335277 | The interplay between protein L-isoaspartyl methyltransferase activity and insulin-like signaling to extend lifespan in Caenorhabditis elegans |
Q37179904 | The longevity effect of cranberry extract in Caenorhabditis elegans is modulated by daf-16 and osr-1 |
Q35079447 | The many forks in FOXO's road |
Q37691144 | The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans |
Q24298020 | The notch regulator MAML1 interacts with p53 and functions as a coactivator |
Q34998152 | The novel hydroxylamine derivative NG-094 suppresses polyglutamine protein toxicity in Caenorhabditis elegans |
Q39964082 | The p38 MAPK PMK-1 shows heat-induced nuclear translocation, supports chaperone expression, and affects the heat tolerance of Caenorhabditis elegans |
Q35105986 | The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor. |
Q33804604 | The protein kinase MBK-1 contributes to lifespan extension in daf-2 mutant and germline-deficient Caenorhabditis elegans |
Q36481541 | The quest for genetic determinants of human longevity: challenges and insights |
Q28083445 | The role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogaster |
Q36310130 | The role of stress in ageing: research on the nematode, Caenorhabditis elegans |
Q37048390 | The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex |
Q42460741 | The von Hippel Lindau tumor suppressor limits longevity |
Q36277196 | Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans |
Q46366442 | Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan |
Q36972178 | To grow or not to grow: nutritional control of development during Caenorhabditis elegans L1 arrest |
Q34084120 | Transcriptional feedback control of insulin receptor by dFOXO/FOXO1. |
Q52102444 | Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16. |
Q33617037 | Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan. |
Q45116957 | Transcriptional targets of DAF-16 insulin signaling pathway protect C. elegans from extreme hypertonic stress |
Q42264027 | Transgenerational Diapause as an Avoidance Strategy against Bacterial Pathogens in Caenorhabditis elegans |
Q91994955 | Treatment of Caenorhabditis elegans with Small Selenium Species Enhances Antioxidant Defense Systems |
Q27315422 | Two membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signaling |
Q28536745 | UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin |
Q37219535 | Ultraviolet-A triggers photoaging in model nematode Caenorhabditis elegans in a DAF-16 dependent pathway. |
Q37515518 | Understanding the molecular basis of Alzheimer's disease using a Caenorhabditis elegans model system |
Q89863572 | Unexpected cell type-dependent effects of autophagy on polyglutamine aggregation revealed by natural genetic variation in C. elegans |
Q28680754 | Unexpected role for dosage compensation in the control of dauer arrest, insulin-like signaling, and FoxO transcription factor activity in Caenorhabditis elegans |
Q38253642 | Use of Caenorhabditis elegans as a model to study Alzheimer's disease and other neurodegenerative diseases |
Q34542345 | Using Caenorhabditis elegans as a model for aging and age-related diseases |
Q26776271 | Using measures of single-cell physiology and physiological state to understand organismic aging |
Q36460071 | Utility of an improved model of amyloid-beta (Aβ₁₋₄₂) toxicity in Caenorhabditis elegans for drug screening for Alzheimer's disease |
Q42018471 | Validated Liquid Culture Monitoring System for Lifespan Extension of Caenorhabditis elegans through Genetic and Dietary Manipulations |
Q46772888 | Valproic acid extends Caenorhabditis elegans lifespan. |
Q33886588 | Variable pathogenicity determines individual lifespan in Caenorhabditis elegans |
Q38681055 | XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity |
Q52736080 | [Aging and the control of the insulin-FOXO signaling pathway]. |
Q39895267 | daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway |
Q27312521 | daf-31 encodes the catalytic subunit of N alpha-acetyltransferase that regulates Caenorhabditis elegans development, metabolism and adult lifespan |
Q37379074 | l-Arginine Enhances Resistance against Oxidative Stress and Heat Stress in Caenorhabditis elegans |
Q27315174 | p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans |
Q47068710 | pkc-1 regulates daf-2 insulin/IGF signalling-dependent control of dauer formation in Caenorhabditis elegans |
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