Abstract is: David Gems is a British geneticist and biogerontologist. He is Professor of Biology of Ageing at University College London where he is also deputy director of the Institute of Healthy Ageing. His work concerns understanding aging through the genetics of C. elegans.
| human | Q5 |
| P6178 | Dimensions author ID | 01127324507.02 |
| P646 | Freebase ID | /m/0fq30pw |
| P496 | ORCID iD | 0000-0002-6653-4676 |
| P1153 | Scopus author ID | 7003303767 |
| P27 | country of citizenship | United Kingdom | Q145 |
| P69 | educated at | University of Sussex | Q1161297 |
| P108 | employer | University College London | Q193196 |
| P22 | father | Keith Gems | Q125525776 |
| P735 | given name | David | Q18057751 |
| David | Q18057751 | ||
| P1412 | languages spoken, written or signed | English | Q1860 |
| P463 | member of | Royal Society | Q123885 |
| P106 | occupation | geneticist | Q3126128 |
| biogerontologist | Q99461909 | ||
| P21 | sex or gender | male | Q6581097 |
| Q34632518 | Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila |
| Q37010759 | Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans |
| Q52586852 | Ageing. Yeast longevity gene goes public. |
| Q59030515 | Ageing: A lethal side-effect |
| Q52102780 | Ageing: Microarraying mortality. |
| Q80872012 | Aging in a very short-lived nematode |
| Q55969555 | Aging: To Treat, or Not to Treat? |
| Q33573959 | Alternative Perspectives on Aging in Caenorhabditis elegans: Reactive Oxygen Species or Hyperfunction? |
| Q33463299 | An 'instant gene bank' method for gene cloning by mutant complementation. |
| Q37723643 | An abundantly expressed mucin-like protein from Toxocara canis infective larvae: the precursor of the larval surface coat glycoproteins |
| Q53863198 | An autonomously replicating plasmid transforms Aspergillus nidulans at high frequency. |
| Q21092703 | Anthranilate fluorescence marks a calcium-propagated necrotic wave that promotes organismal death in C. elegans |
| Q59085743 | Benchmarks for ageing studies |
| Q36504251 | Beyond the evolutionary theory of ageing, from functional genomics to evo-gero |
| Q47173498 | Body size, insulin/IGF signaling and aging in the nematode Caenorhabditis elegans |
| Q36017390 | Broad spectrum detoxification: the major longevity assurance process regulated by insulin/IGF-1 signaling? |
| Q125446753 | C. elegans ageing is accelerated by a self-destructive reproductive programme |
| Q37671507 | Cell-nonautonomous effects of dFOXO/DAF-16 in aging |
| Q36470497 | Clustering of genetically defined allele classes in the Caenorhabditis elegans DAF-2 insulin/IGF-1 receptor |
| Q81322348 | Comment on "Brain IRS2 signaling coordinates life span and nutrient homeostasis" |
| Q47601749 | Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice. |
| Q27317096 | DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans |
| Q34175789 | DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO |
| Q42682055 | Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans |
| Q36129208 | Dietary restriction in C. elegans: from rate-of-living effects to nutrient sensing pathways |
| Q52595511 | Dietary restriction in long-lived dwarf flies. |
| Q63951769 | Dietary restriction in the nematode Caenorhabditis elegans |
| Q34688763 | Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans |
| Q35038739 | Effects of sex and insulin/insulin-like growth factor-1 signaling on performance in an associative learning paradigm in Caenorhabditis elegans |
| Q28679155 | Erratum to "Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans" [Mech. Ageing Dev. 127 (5) (2006) 458-472] |
| Q28252794 | Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice |
| Q36570563 | Evolutionary conservation of regulated longevity assurance mechanisms |
| Q34360039 | Excessive folate synthesis limits lifespan in the C. elegans: E. coli aging model. |
| Q51790474 | Extraordinary plasticity in aging in Strongyloides ratti implies a gene-regulatory mechanism of lifespan evolution. |
| Q73722552 | Genes and ageing: beyond good and evil in the senescent cell |
| Q38063298 | Genetics of longevity in model organisms: debates and paradigm shifts |
| Q35456547 | Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage |
| Q27334849 | Insulin/IGF-1 and hypoxia signaling act in concert to regulate iron homeostasis in Caenorhabditis elegans |
| Q35935123 | Interventions to Slow Aging in Humans: Are We Ready? |
| Q73934913 | Is more life always better? The new biology of aging and the meaning of life |
| Q46704659 | LET-60 RAS modulates effects of insulin/IGF-1 signaling on development and aging in Caenorhabditis elegans |
| Q80499008 | Long-lived dwarf mice: are bile acids a longevity signal? |
| Q51036854 | Longevity in Caenorhabditis elegans reduced by mating but not gamete production. |
| Q43120051 | Longevity of Indy mutant Drosophila not attributable to Indy mutation |
| Q36253932 | Manipulation of in vivo iron levels can alter resistance to oxidative stress without affecting ageing in the nematode C. elegans |
| Q35549813 | Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix |
| Q34611857 | Mechanisms of ageing: public or private? |
| Q47947920 | Metabolic rate is not reduced by dietary-restriction or by lowered insulin/IGF-1 signalling and is not correlated with individual lifespan in Drosophila melanogaster |
| Q37503122 | Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism. |
| Q48065198 | Multiple copies of MATE elements support autonomous plasmid replication in Aspergillus nidulans |
| Q91915881 | New label-free automated survival assays reveal unexpected stress resistance patterns during C. elegans aging |
| Q78772821 | No increase in lifespan in Caenorhabditis elegans upon treatment with the superoxide dismutase mimetic EUK-8 |
| Q33287882 | No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects |
| Q30360015 | RILM: a web-based resource to aid comparative and functional analysis of the insulin and IGF-1 receptor family. |
| Q36056296 | Sex and death: what is the connection? |
| Q35103830 | Sex-specific effects of the DAF-12 steroid receptor on aging in Caenorhabditis elegans |
| Q38337791 | Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance |
| Q92007454 | Shorter life and reduced fecundity can increase colony fitness in virtual Caenorhabditis elegans |
| Q34757662 | Stress-response hormesis and aging: "that which does not kill us makes us stronger". |
| Q44941245 | Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard aging in the nematode Caenorhabditis elegans |
| Q43170158 | The 'mitoflash' probe cpYFP does not respond to superoxide |
| Q38542056 | The aging-disease false dichotomy: understanding senescence as pathology |
| Q21131240 | The mysterious case of the C. elegans gut granule: death fluorescence, anthranilic acid and the kynurenine pathway |
| Q37988793 | The mystery of C. elegans aging: an emerging role for fat. Distant parallels between C. elegans aging and metabolic syndrome? |
| Q37691144 | The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans |
| Q34402742 | Tragedy and delight: the ethics of decelerated ageing. |
| Q57064173 | Transcript profiles of long- and short-lived adults implicate protein synthesis in evolved differences in ageing in the nematode Strongyloides ratti |
| Q35653213 | Unraveling the biological roles of reactive oxygen species |
| Q36017401 | What are the effects of maternal and pre-adult environments on ageing in humans, and are there lessons from animal models? |
| Q44361039 | What is an anti-aging treatment? |
| Q34361733 | Worms need microbes too: microbiota, health and aging in Caenorhabditis elegans |
| David Gems | wikipedia |
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