| scholarly article | Q13442814 |
| P2093 | author name string | Charles H Lang | |
| Abid A Kazi | |||
| Ly Q Hong-Brown | |||
| P2860 | cites work | Raptor-rictor axis in TGFbeta-induced protein synthesis. | Q42522320 |
| Elongation factor-2 kinase: immunological evidence for the existence of tissue-specific isoforms | Q42807222 | ||
| A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors | Q43613003 | ||
| Effects of chronic alcohol consumption on regulation of myocardial protein synthesis | Q43713909 | ||
| Alcohol impairs insulin and IGF-I stimulation of S6K1 but not 4E-BP1 in skeletal muscle | Q44176897 | ||
| Alcohol impairs leucine-mediated phosphorylation of 4E-BP1, S6K1, eIF4G, and mTOR in skeletal muscle | Q44565849 | ||
| Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte | Q44907827 | ||
| Cellular energy status modulates translational control mechanisms in ischemic-reperfused rat hearts | Q46491177 | ||
| ETOH inhibits embryonic neural stem/precursor cell proliferation via PLD signaling | Q46688643 | ||
| Ethanol consumption impairs regulation of fatty acid metabolism by decreasing the activity of AMP-activated protein kinase in rat liver | Q46904344 | ||
| Alcohol and indinavir adversely affect protein synthesis and phosphorylation of MAPK and mTOR signaling pathways in C2C12 myocytes | Q47191684 | ||
| Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer | Q48087617 | ||
| PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling | Q53331675 | ||
| Impaired myocardial protein synthesis induced by acute alcohol intoxication is associated with changes in eIF4F | Q73127275 | ||
| Impaired protein synthesis induced by acute alcohol intoxication is associated with changes in eIF4E in muscle and eIF2B in liver | Q73702282 | ||
| 14-3-3 proteins: a number of functions for a numbered protein | Q81038465 | ||
| Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex | Q24295120 | ||
| Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton | Q24299873 | ||
| PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase | Q24300915 | ||
| mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery | Q24302549 | ||
| Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action | Q24302566 | ||
| Identification of Protor as a novel Rictor-binding component of mTOR complex-2 | Q24303936 | ||
| Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive | Q24306328 | ||
| Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids | Q24306330 | ||
| DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival | Q24311448 | ||
| Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control | Q24314363 | ||
| The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1 | Q24315566 | ||
| PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex | Q24316314 | ||
| Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase | Q24319188 | ||
| Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning | Q24320102 | ||
| Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling | Q24323370 | ||
| mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1) | Q24324148 | ||
| AMPK phosphorylation of raptor mediates a metabolic checkpoint | Q24329244 | ||
| Identification of a proline-rich Akt substrate as a 14-3-3 binding partner | Q24338582 | ||
| Systematic review and meta-analysis of evidence for increasing numbers of drugs in antiretroviral combination therapy | Q24514773 | ||
| Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways | Q24534710 | ||
| Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase. | Q24535599 | ||
| A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38delta | Q24535672 | ||
| Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism | Q24608263 | ||
| Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucine | Q24633679 | ||
| Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1 | Q24645183 | ||
| A complex interplay between Akt, TSC2 and the two mTOR complexes | Q24655791 | ||
| Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling | Q24672005 | ||
| TOR signaling in growth and metabolism | Q27860757 | ||
| eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation | Q27860920 | ||
| TSC2 mediates cellular energy response to control cell growth and survival | Q27860970 | ||
| Rag proteins regulate amino-acid-induced mTORC1 signalling. | Q27863397 | ||
| TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling | Q28131740 | ||
| Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2 | Q28181376 | ||
| Phosphatidic Acid-Mediated Mitogenic Activation of mTOR Signaling | Q28208274 | ||
| Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis | Q28218978 | ||
| Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis | Q28246808 | ||
| Rheb binds and regulates the mTOR kinase | Q28247033 | ||
| Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency | Q28249019 | ||
| mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s | Q28258807 | ||
| Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1 | Q28276788 | ||
| Upstream and downstream of mTOR | Q28277365 | ||
| Phosphorylation of elongation factor 2 by EF-2 kinase affects rate of translation | Q28297499 | ||
| Involvement of AMPK in alcohol dehydrogenase accentuated myocardial dysfunction following acute ethanol challenge in mice | Q28474635 | ||
| AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress | Q28570993 | ||
| Inhibitory effect of ethanol on AMPK phosphorylation is mediated in part through elevated ceramide levels | Q28578006 | ||
| The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C | Q28587901 | ||
| Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway | Q28646919 | ||
| Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators | Q29547281 | ||
| Regulation of TORC1 by Rag GTPases in nutrient response | Q29614478 | ||
| Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress | Q29614493 | ||
| Molecular mechanisms of mTOR-mediated translational control | Q29615529 | ||
| Growing roles for the mTOR pathway | Q29616212 | ||
| Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40 | Q29617097 | ||
| Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation | Q30439476 | ||
| Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway | Q33480974 | ||
| Aldehyde dehydrogenase 2 knockout accentuates ethanol-induced cardiac depression: role of protein phosphatases | Q33912694 | ||
| Biology of Cachexia | Q34065627 | ||
| Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway | Q34085728 | ||
| Skeletal muscle loss: cachexia, sarcopenia, and inactivity | Q34099406 | ||
| How do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesis | Q34120299 | ||
| Catabolic response to stress and injury: implications for regulation | Q34148735 | ||
| Proline-rich Akt substrate of 40kDa (PRAS40): a novel downstream target of PI3k/Akt signaling pathway. | Q34215075 | ||
| Alcohol myopathy: impairment of protein synthesis and translation initiation | Q34237499 | ||
| Mechanisms Involved in the Coordinate Regulation of mTORC1 by Insulin and Amino Acids | Q34624351 | ||
| Regulation of muscle protein synthesis during sepsis and inflammation | Q34628735 | ||
| Phospholipase D1 is an effector of Rheb in the mTOR pathway. | Q34786317 | ||
| Regulation of peptide-chain elongation in mammalian cells | Q34992462 | ||
| 14-3-3 proteins in pineal photoneuroendocrine transduction: how many roles? | Q35080095 | ||
| The Mechanism of Insulin-stimulated 4E-BP Protein Binding to Mammalian Target of Rapamycin (mTOR) Complex 1 and Its Contribution to mTOR Complex 1 Signaling | Q35515514 | ||
| Rag GTPases and AMPK/TSC2/Rheb mediate the differential regulation of mTORC1 signaling in response to alcohol and leucine | Q35993758 | ||
| Alcohol-Induced Modulation of Rictor and mTORC2 Activity in C2C12 Myoblasts | Q36415019 | ||
| AMP-activated protein kinase signaling in metabolic regulation | Q36528537 | ||
| Acute and chronic ethanol consumption differentially impact pathways limiting hepatic protein synthesis | Q36805481 | ||
| Alcohol and PRAS40 knockdown decrease mTOR activity and protein synthesis via AMPK signaling and changes in mTORC1 interaction | Q36852932 | ||
| Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin | Q37110578 | ||
| Amino acid regulation of TOR complex 1. | Q37162253 | ||
| Regulation of protein synthesis at the elongation stage New insights into the control of gene expression in eukaryotes | Q37191842 | ||
| Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms. | Q37376549 | ||
| Nutrient control of TORC1, a cell-cycle regulator | Q37472419 | ||
| Mechanisms of amino acid sensing in mTOR signaling pathway | Q37657110 | ||
| mTORC1 signaling: what we still don't know | Q37817590 | ||
| The capture of phosphoproteins by 14-3-3 proteins mediates actions of insulin. | Q37922928 | ||
| AICAR, an AMPK activator, has protective effects on alcohol-induced fatty liver in rats | Q38317237 | ||
| Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2. | Q39700543 | ||
| mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling | Q39765614 | ||
| Rictor is a novel target of p70 S6 kinase-1. | Q39771171 | ||
| mTORC2 activity is elevated in gliomas and promotes growth and cell motility via overexpression of rictor | Q40033644 | ||
| Alcohol regulates eukaryotic elongation factor 2 phosphorylation via an AMP-activated protein kinase-dependent mechanism in C2C12 skeletal myocytes | Q40197427 | ||
| HIV antiretroviral agents inhibit protein synthesis and decrease ribosomal protein S6 and 4EBP1 phosphorylation in C2C12 myocytes | Q40362104 | ||
| Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control. | Q40456155 | ||
| The role of AMP-activated protein kinase in the action of ethanol in the liver | Q40485116 | ||
| The HIV wasting syndrome: a review | Q40698582 | ||
| ESBRA 1994 Award Lecture. Phosphatidylethanol formation: specific effects of ethanol mediated via phospholipase D. | Q40934427 | ||
| Lopinavir impairs protein synthesis and induces eEF2 phosphorylation via the activation of AMP-activated protein kinase | Q41920342 | ||
| Indinavir impairs protein synthesis and phosphorylations of MAPKs in mouse C2C12 myocytes | Q42464012 | ||
| Lopinavir inhibits meningioma cell proliferation by Akt independent mechanism | Q42473677 | ||
| Indinavir alters regulators of protein anabolism and catabolism in skeletal muscle | Q42476875 | ||
| Alcohol impairs protein synthesis and degradation in cultured skeletal muscle cells | Q42510878 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 110-120 | |
| P577 | publication date | 2012-06-01 | |
| P1433 | published in | World journal of biological chemistry | Q27723536 |
| P1476 | title | Mechanisms mediating the effects of alcohol and HIV anti-retroviral agents on mTORC1, mTORC2 and protein synthesis in myocytes | |
| P478 | volume | 3 |
| Q37266159 | Activation of AMPK/TSC2/PLD by Alcohol Regulates mTORC1 and mTORC2 Assembly in C2C12 Myocytes |
| Q26826554 | Dysregulation of skeletal muscle protein metabolism by alcohol |
| Q54980051 | Ethanol-Induced Changes in PKCε: From Cell to Behavior. |
| Q38628906 | Increased autolysis of μ-calpain in skeletal muscles of chronic alcohol-fed rats |
| Q41091103 | Protein Kinase C Epsilon Activity in the Nucleus Accumbens and Central Nucleus of the Amygdala Mediates Binge Alcohol Consumption |
| Q37374462 | The human myometrium differentially expresses mTOR signalling components before and during pregnancy: evidence for regulation by progesterone. |
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