| scholarly article | Q13442814 |
| P356 | DOI | 10.1152/AJPENDO.00204.2007 |
| P698 | PubMed publication ID | 17505052 |
| P2093 | author name string | Charles H Lang | |
| Thomas C Vary | |||
| Robert A Frost | |||
| P2860 | cites work | The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity | Q24293101 |
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| Endotoxin disrupts the leucine-signaling pathway involving phosphorylation of mTOR, 4E-BP1, and S6K1 in skeletal muscle | Q28576832 | ||
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| Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation? | Q34992458 | ||
| Specific isoforms of translation initiation factor 4GI show differences in translational activity | Q35131555 | ||
| Glucocorticoids and TNFalpha interact cooperatively to mediate sepsis-induced leucine resistance in skeletal muscle | Q35690899 | ||
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| The amino acid sensitive TOR pathway from yeast to mammals. | Q36473396 | ||
| Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1. | Q36497296 | ||
| Protein kinase B/Akt: a nexus of growth factor and cytokine signaling in determining muscle mass | Q36749035 | ||
| Stopped-flow kinetic analysis of eIF4E and phosphorylated eIF4E binding to cap analogs and capped oligoribonucleotides: evidence for a one-step binding mechanism | Q38314964 | ||
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| Ubiquitination and proteasome-dependent degradation of human eukaryotic translation initiation factor 4E. | Q40276347 | ||
| Multiple Toll-like receptor ligands induce an IL-6 transcriptional response in skeletal myocytes | Q40357261 | ||
| hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase | Q40392574 | ||
| Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control. | Q40456155 | ||
| Acute treatment with TNF-alpha attenuates insulin-stimulated protein synthesis in cultures of C2C12 myotubes through a MEK1-sensitive mechanism. | Q40460377 | ||
| Signal transduction pathways leading to increased eIF4E phosphorylation caused by oxidative stress. | Q40463510 | ||
| Proinflammatory cytokine impairment of insulin-like growth factor I-induced protein synthesis in skeletal muscle myoblasts requires ceramide. | Q40534790 | ||
| Tumor Necrosis Factor-α Decreases Insulin-Like Growth Factor-I Messenger Ribonucleic Acid Expression in C2C12 Myoblasts via a Jun N-Terminal Kinase Pathway | Q40655133 | ||
| Compartmentalisation and localisation of the translation initiation factor (eIF) 4F complex in normally growing fibroblasts | Q42799366 | ||
| Absence of peroxisome proliferators-activated receptors (PPAR)alpha enhanced the multiple organ failure induced by zymosan | Q43433099 | ||
| Lipopolysaccharide regulates proinflammatory cytokine expression in mouse myoblasts and skeletal muscle | Q44107264 | ||
| Sepsis-induced insulin resistance in rats is mediated by a beta-adrenergic mechanism | Q44387308 | ||
| Endotoxin induces differential regulation of mTOR-dependent signaling in skeletal muscle and liver of neonatal pigs | Q44457694 | ||
| Differential effect of sepsis on ability of leucine and IGF-I to stimulate muscle translation initiation | Q44928884 | ||
| NOS3 is involved in the increased protein and arginine metabolic response in muscle during early endotoxemia in mice | Q45219974 | ||
| Modulation of muscle protein synthesis by insulin is maintained during neonatal endotoxemia | Q46944962 | ||
| Inhibition of Cap-initiation complexes linked to a novel mechanism of eIF4G depletion in acute myocardial ischemia | Q52568479 | ||
| Insulin fails to stimulate muscle protein synthesis in sepsis despite unimpaired signaling to 4E-BP1 and S6K1. | Q53991546 | ||
| IL-1 receptor antagonist attenuates sepsis-induced alterations in the IGF system and protein synthesis. | Q54593001 | ||
| Sepsis-induced changes in protein synthesis: differential effects on fast- and slow-twitch muscles | Q54678333 | ||
| P433 | issue | 2 | |
| P921 | main subject | sepsis | Q183134 |
| P304 | page(s) | E453-9 | |
| P577 | publication date | 2007-05-15 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | American Journal of Physiology - Endocrinology and Metabolism | Q15765671 |
| P1476 | title | Regulation of muscle protein synthesis during sepsis and inflammation | |
| P478 | volume | 293 |
| Q46346112 | A potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle. |
| Q37629020 | A validation of the application of D(2)O stable isotope tracer techniques for monitoring day-to-day changes in muscle protein subfraction synthesis in humans |
| Q33869877 | Activated protein synthesis and suppressed protein breakdown signaling in skeletal muscle of critically ill patients |
| Q37000863 | Activation of AMP-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleoside prevents leucine-stimulated protein synthesis in rat skeletal muscle |
| Q40003242 | Acute alcohol intoxication increases REDD1 in skeletal muscle |
| Q45905655 | Acute uremia suppresses leucine-induced signal transduction in skeletal muscle |
| Q47135931 | Age-related sarcopenia and its pathophysiological bases |
| Q38075348 | Albumin synthesis in surgical patients |
| Q37201322 | Amino acids, independent of insulin, attenuate skeletal muscle autophagy in neonatal pigs during endotoxemia |
| Q34150233 | BCATm deficiency ameliorates endotoxin-induced decrease in muscle protein synthesis and improves survival in septic mice. |
| Q37578972 | Basic and translational research: from molecule, to mouse, to man. |
| Q37623067 | Bench-to-bedside review: Beta-adrenergic modulation in sepsis. |
| Q34789287 | Body weight-dependent troponin T alternative splicing is evolutionarily conserved from insects to mammals and is partially impaired in skeletal muscle of obese rats |
| Q42144502 | C/EBPβ regulates dexamethasone‐induced muscle cell atrophy and expression of atrogin‐1 and MuRF1 |
| Q36956035 | Calpain activity and muscle wasting in sepsis |
| Q83226333 | Chronic muscle weakness and mitochondrial dysfunction in the absence of sustained atrophy in a preclinical sepsis model |
| Q37332891 | Curcumin and muscle wasting: a new role for an old drug? |
| Q37781997 | Cytokine gene polymorphisms and susceptibility to cachexia |
| Q34321178 | Delayed Recovery of Skeletal Muscle Mass following Hindlimb Immobilization in mTOR Heterozygous Mice |
| Q35842227 | Development aggravates the severity of skeletal muscle catabolism induced by endotoxemia in neonatal pigs |
| Q36751821 | Disruption of REDD1 gene ameliorates sepsis-induced decrease in mTORC1 signaling but has divergent effects on proteolytic signaling in skeletal muscle |
| Q26826554 | Dysregulation of skeletal muscle protein metabolism by alcohol |
| Q28571670 | Ectopic expression of eIF2Bepsilon in rat skeletal muscle rescues the sepsis-induced reduction in guanine nucleotide exchange activity and protein synthesis |
| Q33504197 | Effects of endotoxaemia on protein metabolism in rat fast-twitch skeletal muscle and myocardium |
| Q91605371 | Elevated serum Activin A in chronic obstructive pulmonary disease with skeletal muscle wasting |
| Q37281129 | Endotoxin-induced growth hormone resistance in skeletal muscle |
| Q35558447 | Ethyl Pyruvate Preserves IGF-I Sensitivity toward mTOR Substrates and Protein Synthesis in C2C12 Myotubes |
| Q46107012 | Excessive energy intake does not modify fed-state tissue protein synthesis rates in adult rats |
| Q34542081 | Exercise Training Prevents TNF-α Induced Loss of Force in the Diaphragm of Mice |
| Q38617839 | Experimental Periodontitis in the Potentialization of the Effects of Immobilism in the Skeletal Striated Muscle |
| Q30898776 | Gene network and pathway analysis of bovine mammary tissue challenged with Streptococcus uberis reveals induction of cell proliferation and inhibition of PPARgamma signaling as potential mechanism for the negative relationships between immune [...] |
| Q41255629 | Glutamate alleviates muscle protein loss by modulating TLR4, NODs, Akt/FOXO and mTOR signaling pathways in LPS-challenged piglets. |
| Q54332960 | Glycine enhances muscle protein mass associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing TLR4 and NOD2 signaling in piglets challenged with LPS. |
| Q36150568 | Higher IL-6 and IL6:IGF Ratio in Patients with Barth Syndrome |
| Q34974513 | Human slow troponin T (TNNT1) pre-mRNA alternative splicing is an indicator of skeletal muscle response to resistance exercise in older adults. |
| Q27024703 | IL-6 and IGF-1 Signaling Within and Between Muscle and Bone: How Important is the mTOR Pathway for Bone Metabolism? |
| Q92589130 | Immune System Stimulation Reduces the Efficiency of Whole-Body Protein Deposition and Alters Muscle Fiber Characteristics in Growing Pigs |
| Q47996428 | In utero LPS exposure impairs preterm diaphragm contractility. |
| Q39013918 | Inability to replete white adipose tissue during recovery phase of sepsis is associated with increased autophagy, apoptosis, and proteasome activity |
| Q37341440 | Inflammatory burden and amino acid metabolism in cancer cachexia. |
| Q28576092 | Inhibition of Glycogen Synthase Kinase 3β Activity with Lithium In Vitro Attenuates Sepsis-Induced Changes in Muscle Protein Turnover |
| Q40473610 | Insulin modulates energy and substrate sensing and protein catabolism induced by chronic peritonitis in skeletal muscle of neonatal pigs. |
| Q37414140 | Insulin signaling in skeletal muscle and liver of neonatal pigs during endotoxemia |
| Q34697264 | Intensive care unit-acquired weakness (ICUAW) and muscle wasting in critically ill patients with severe sepsis and septic shock |
| Q57213746 | Inverse relationship between serum hsCRP concentration and hand grip strength in older adults: a nationwide population-based study |
| Q37713538 | Length of hospitalization is associated with selected biomarkers (albumin and lymphocytes) and with co-morbidities: study on 4000 patients. |
| Q40541664 | Leucine supplementation stimulates protein synthesis and reduces degradation signal activation in muscle of newborn pigs during acute endotoxemia. |
| Q45045040 | Leucine-stimulated mTOR signaling is partly attenuated in skeletal muscle of chronically uremic rats |
| Q37381871 | Local insulin-like growth factor I prevents sepsis-induced muscle atrophy |
| Q39396142 | MNK2 Inhibits eIF4G Activation Through a Pathway Involving Serine-Arginine–Rich Protein Kinase in Skeletal Muscle |
| Q37419009 | Marginal dietary zinc deprivation augments sepsis-induced alterations in skeletal muscle TNF-α but not protein synthesis |
| Q36170398 | Mechanisms mediating the effects of alcohol and HIV anti-retroviral agents on mTORC1, mTORC2 and protein synthesis in myocytes |
| Q26744385 | MicroRNA-Regulated Proinflammatory Cytokines in Sarcopenia |
| Q35163917 | Mobilization in severe sepsis: an integrative review. |
| Q36593132 | Modulation of the gut microbiota with antibiotic treatment suppresses whole body urea production in neonatal pigs |
| Q92857404 | Molecular Mechanisms Responsible for the Rescue Effects of Pamidronate on Muscle Atrophy in Pediatric Burn Patients |
| Q43594462 | Molecules modulating gene transcription during muscle wasting in cancer, sepsis, and other critical illness |
| Q57580280 | Muscle Atrophy Due to Nerve Damage Is Accompanied by Elevated Myofibrillar Protein Synthesis Rates |
| Q54582240 | Novel events in the molecular regulation of muscle mass in critically ill patients. |
| Q34179131 | Omega-3 polyunsaturated fatty acids augment the muscle protein anabolic response to hyperinsulinaemia–hyperaminoacidaemia in healthy young and middle-aged men and women |
| Q43139168 | Overexpression of parkin in the rat nigrostriatal dopamine system protects against methamphetamine neurotoxicity |
| Q57522046 | Postmortem tandem mass spectrometry profiling for detection of infection in unexpected infant death |
| Q37421345 | Preventive effects of kilohertz frequency electrical stimulation on sepsis-induced muscle atrophy |
| Q35532243 | Protein Ingestion Induces Muscle Insulin Resistance Independent of Leucine-Mediated mTOR Activation |
| Q38733533 | Protein Requirements of the Critically Ill Pediatric Patient |
| Q55033522 | Pulmonary inflammation-induced loss and subsequent recovery of skeletal muscle mass require functional poly-ubiquitin conjugation. |
| Q28573743 | REDD1 is a major target of testosterone action in preventing dexamethasone-induced muscle loss |
| Q37139068 | REDD2 is enriched in skeletal muscle and inhibits mTOR signaling in response to leucine and stretch |
| Q35880350 | Regulation of REDD1 by insulin-like growth factor-I in skeletal muscle and myotubes |
| Q28564515 | Regulation of signaling pathways downstream of IGF-I/insulin by androgen in skeletal muscle of glucocorticoid-treated rats |
| Q58765520 | Repurposing Thioridazine (TDZ) as an anti-inflammatory agent |
| Q51384750 | Restorative Mechanisms Regulating Protein Balance in Skeletal Muscle During Recovery From Sepsis. |
| Q36905257 | Ribosome biogenesis: emerging evidence for a central role in the regulation of skeletal muscle mass. |
| Q33908646 | Role of AMPK α in skeletal muscle glycometabolism regulation and adaptation in relation to sepsis |
| Q27025502 | Role of specific dietary amino acids in clinical conditions |
| Q36017207 | SS-31 attenuates TNF-α induced cytokine release from C2C12 myotubes |
| Q37000179 | Sepsis and AMPK Activation by AICAR Differentially Regulate FoxO-1, -3 and -4 mRNA in Striated Muscle |
| Q34958917 | Sepsis and Development Impede Muscle Protein Synthesis in Neonatal Pigs by Different Ribosomal Mechanisms |
| Q28574576 | Sepsis and glucocorticoids upregulate p300 and downregulate HDAC6 expression and activity in skeletal muscle |
| Q35177499 | Sepsis attenuates the anabolic response to skeletal muscle contraction |
| Q42949695 | Sepsis downregulates myostatin mRNA levels without altering myostatin protein levels in skeletal muscle |
| Q34372599 | Sepsis-induced alterations in protein-protein interactions within mTOR complex 1 and the modulating effect of leucine on muscle protein synthesis |
| Q37666348 | Sepsis-induced myopathy |
| Q51426264 | Serum myostatin levels and skeletal muscle wasting in chronic obstructive pulmonary disease |
| Q36956010 | Skeletal and cardiac myopathy in HIV-1 transgenic rats |
| Q34137976 | Skeletal muscle catabolism in trinitrobenzene sulfonic acid-induced murine colitis |
| Q24633679 | Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucine |
| Q36882862 | Sleep, Muscle Mass and Muscle Function in Older People |
| Q37456616 | Soluble CD14 levels, interleukin 6, and mortality among prevalent hemodialysis patients. |
| Q36246665 | Targeting anabolic impairment in response to resistance exercise in older adults with mobility impairments: potential mechanisms and rehabilitation approaches. |
| Q34483183 | The Sick and the Weak: Neuropathies/Myopathies in the Critically Ill. |
| Q41636004 | The activation of α2-adrenergic receptor in the spinal cord lowers sepsis-induced mortality |
| Q37260905 | The hepatic response to thermal injury: is the liver important for postburn outcomes? |
| Q35747549 | The pathogenetic bases of sarcopenia |
| Q47573911 | Therapeutic potency of mTOR signaling pharmacological inhibitors in the treatment of proinflammatory diseases, current status, and perspectives. |
| Q28475735 | Tumor necrosis factor-α regulates distinct molecular pathways and gene networks in cultured skeletal muscle cells |
| Q46084493 | Understanding the metabolic responses to sepsis |
| Q50661404 | Variation in Protein Origin and Utilization: Research and Clinical Application |
| Q36711877 | mTor Signaling in Skeletal Muscle During Sepsis and Inflammation: Where Does It All Go Wrong? |
| Q47320378 | miR-424-5p reduces ribosomal RNA and protein synthesis in muscle wasting. |
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