| scholarly article | Q13442814 |
| P50 | author | Christopher J Lynch | Q57319887 |
| P2093 | author name string | Charles H Lang | |
| Thomas C Vary | |||
| P2860 | cites work | mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery | Q24302549 |
| Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action | Q24302566 | ||
| Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive | Q24306328 | ||
| Identification of a proline-rich Akt substrate as a 14-3-3 binding partner | Q24338582 | ||
| Crystal structures of human mitochondrial branched chain aminotransferase reaction intermediates: ketimine and pyridoxamine phosphate forms | Q27639682 | ||
| The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif | Q28211968 | ||
| mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events | Q28281590 | ||
| PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding | Q28302887 | ||
| Endotoxin disrupts the leucine-signaling pathway involving phosphorylation of mTOR, 4E-BP1, and S6K1 in skeletal muscle | Q28576832 | ||
| Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy | Q28582211 | ||
| Alcohol-induced IGF-I resistance is ameliorated in mice deficient for mitochondrial branched-chain aminotransferase | Q28592130 | ||
| Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle | Q28593294 | ||
| Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40 | Q29617097 | ||
| Interleukin-6 causes myocardial failure and skeletal muscle atrophy in rats | Q34394314 | ||
| Leucine. A possible regulator of protein turnover in muscle | Q34484538 | ||
| TNF-alpha impairs heart and skeletal muscle protein synthesis by altering translation initiation | Q58111846 | ||
| Fractional flux rates of Nt-methylhistidine in skin and gastrointestine: the contribution of these tissues to urinary excretion of Nt-methylhistidine in the rat | Q67651391 | ||
| Evidence that tumor necrosis factor participates in the regulation of muscle proteolysis during sepsis | Q68063740 | ||
| Modulation of skeletal muscle protein synthesis by amino acids and insulin during sepsis | Q71709161 | ||
| Reduced muscle protein breakdown in septic rats following treatment with interleukin-1 receptor antagonist | Q72134522 | ||
| Endotoxin-induced decrease in muscle protein synthesis is associated with changes in eIF2B, eIF4E, and IGF-I | Q73825518 | ||
| Animal research. Harmonization of animal care and use guidance | Q83289343 | ||
| eIF3: a versatile scaffold for translation initiation complexes | Q34558903 | ||
| Sepsis-induced suppression of skeletal muscle translation initiation mediated by tumor necrosis factor alpha | Q34589839 | ||
| Regulation of muscle protein synthesis during sepsis and inflammation | Q34628735 | ||
| Glucocorticoids and TNFalpha interact cooperatively to mediate sepsis-induced leucine resistance in skeletal muscle | Q35690899 | ||
| Endotoxin and interferon-gamma inhibit translation in skeletal muscle cells by stimulating nitric oxide synthase activity | Q35880345 | ||
| Animal models of sepsis: setting the stage | Q36285943 | ||
| Therapeutic use of branched-chain amino acids in burn, trauma, and sepsis | Q36347165 | ||
| Immunonutrition in surgery and critical care | Q36480502 | ||
| Calpain activity and muscle wasting in sepsis | Q36956035 | ||
| Sepsis and AMPK Activation by AICAR Differentially Regulate FoxO-1, -3 and -4 mRNA in Striated Muscle | Q37000179 | ||
| Activation of AMP-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleoside prevents leucine-stimulated protein synthesis in rat skeletal muscle | Q37000863 | ||
| Regulation of muscle growth by pathogen-associated molecules | Q37056056 | ||
| Assessing effects of alcohol consumption on protein synthesis in striated muscles | Q37120412 | ||
| Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms. | Q37376549 | ||
| Local insulin-like growth factor I prevents sepsis-induced muscle atrophy | Q37381871 | ||
| Animal models of maple syrup urine disease | Q37407144 | ||
| Sepsis increases the expression and activity of the transcription factor Forkhead Box O 1 (FOXO1) in skeletal muscle by a glucocorticoid-dependent mechanism | Q39751365 | ||
| Measurement of tissue protein synthesis rates in vivo: a critical analysis of contrasting methods | Q40744468 | ||
| Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6. | Q40960220 | ||
| Regulation of eIF-4E BP1 phosphorylation by mTOR. | Q41087062 | ||
| Widespread neuronal expression of branched-chain aminotransferase in the CNS: implications for leucine/glutamate metabolism and for signaling by amino acids | Q42509436 | ||
| Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation | Q43201824 | ||
| Protein metabolism in leg muscle following an endotoxin injection in healthy volunteers | Q43277069 | ||
| Lipopolysaccharide regulates proinflammatory cytokine expression in mouse myoblasts and skeletal muscle | Q44107264 | ||
| Potential role of leucine metabolism in the leucine-signaling pathway involving mTOR. | Q44482073 | ||
| Regulation of muscle protein synthesis in neonatal pigs during prolonged endotoxemia | Q44697448 | ||
| Differential effect of sepsis on ability of leucine and IGF-I to stimulate muscle translation initiation | Q44928884 | ||
| Blocking eukaryotic initiation factor 4F complex formation does not inhibit the mTORC1-dependent activation of protein synthesis in cardiomyocytes | Q46202292 | ||
| A molecular model of human branched-chain amino acid metabolism | Q46762438 | ||
| Identification of mitochondrial branched chain aminotransferase and its isoforms in rat tissues | Q48445960 | ||
| Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway | Q48701446 | ||
| Influence of amino acid availability on protein turnover in perfused skeletal muscle | Q51663760 | ||
| Protective effects of regulatory amino acids on ischemia-reperfusion injury in the isolated perfused rat liver | Q51930409 | ||
| Protein synthesis and degradation in skeletal muscle from septic rats. Response to leucine and alpha-ketoisocaproic acid | Q54384089 | ||
| IL-1 receptor antagonist attenuates sepsis-induced alterations in the IGF system and protein synthesis. | Q54593001 | ||
| Sepsis-induced changes in protein synthesis: differential effects on fast- and slow-twitch muscles | Q54678333 | ||
| P4510 | describes a project that uses | ImageQuant | Q112270642 |
| P433 | issue | 3 | |
| P921 | main subject | sepsis | Q183134 |
| endotoxins | Q319997 | ||
| P304 | page(s) | R935-44 | |
| P577 | publication date | 2010-06-16 | |
| P1433 | published in | American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | Q2201819 |
| P1476 | title | BCATm deficiency ameliorates endotoxin-induced decrease in muscle protein synthesis and improves survival in septic mice | |
| P478 | volume | 299 |
| Q55315671 | A Novel Whole Gene Deletion of BCKDHB by Alu-Mediated Non-allelic Recombination in a Chinese Patient With Maple Syrup Urine Disease. |
| Q34069683 | Abandon the mouse research ship? Not just yet! |
| Q34519008 | Alcohol impairs skeletal muscle protein synthesis and mTOR signaling in a time-dependent manner following electrically stimulated muscle contraction |
| Q35020928 | Alcohol intoxication following muscle contraction in mice decreases muscle protein synthesis but not mTOR signal transduction |
| Q27342729 | Branched-chain amino acid catabolism is a conserved regulator of physiological ageing |
| Q34321178 | Delayed Recovery of Skeletal Muscle Mass following Hindlimb Immobilization in mTOR Heterozygous Mice |
| Q35286938 | Deptor Knockdown Enhances mTOR Activity and Protein Synthesis in Myocytes and Ameliorates Disuse Muscle Atrophy |
| Q33778791 | Disruption of genes encoding eIF4E binding proteins-1 and -2 does not alter basal or sepsis-induced changes in skeletal muscle protein synthesis in male or female mice |
| Q26826554 | Dysregulation of skeletal muscle protein metabolism by alcohol |
| Q36237292 | Global deletion of BCATm increases expression of skeletal muscle genes associated with protein turnover |
| Q41355931 | Maple syrup urine disease: mechanisms and management |
| Q27009396 | Multifaceted Role of Insulin-Like Growth Factors and Mammalian Target of Rapamycin in Skeletal Muscle |
| Q27000450 | Muscle wasting in animal models of severe illness |
| Q88541681 | Post-ruminal branched-chain amino acid supplementation and intravenous lipopolysaccharide infusion alter blood metabolites, rumen fermentation, and nitrogen balance of beef steers |
| Q29614493 | Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress |
| Q33901148 | Salutary effect of aurintricarboxylic acid on endotoxin- and sepsis-induced changes in muscle protein synthesis and inflammation |
| Q35177499 | Sepsis attenuates the anabolic response to skeletal muscle contraction |
| Q36711877 | mTor Signaling in Skeletal Muscle During Sepsis and Inflammation: Where Does It All Go Wrong? |
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