Local insulin-like growth factor I prevents sepsis-induced muscle atrophy

scientific article published on June 2009

Local insulin-like growth factor I prevents sepsis-induced muscle atrophy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.METABOL.2009.01.015
P932PMC publication ID2759714
P698PubMed publication ID19375133
P5875ResearchGate publication ID24306243

P2093author name stringCharles H Lang
Robert A Frost
Anne Pruznak
Danuta Huber
Gerald Nystrom
P2860cites workIGF-I/IGFBP-3 ameliorates alterations in protein synthesis, eIF4E availability, and myostatin in alcohol-fed ratsQ28568822
Anabolic effects of insulin-like growth factor in combination with insulin-like growth factor binding protein-3 in severely burned adultsQ73198506
Insulin-like growth factor I reduces ubiquitin and ubiquitin-conjugating enzyme gene expression but does not inhibit muscle proteolysis in septic ratsQ74086347
Glucocorticoid effects on insulin- and IGF-I-regulated muscle protein metabolism during agingQ74295801
Localized infusion of IGF-I results in skeletal muscle hypertrophy in ratsQ74510959
Overexpression of IGF-I in skeletal muscle of transgenic mice does not prevent unloading-induced atrophyQ77189365
Evolution of insulin-like growth factor-I (IGF-I) action: in vitro characterization of vertebrate IGF-I proteinsQ78106600
Differential effects of insulin-like growth factor I (IGF-I) and IGF-binding protein-1 on protein metabolism in human skeletal muscle cellsQ78180899
Hormone, cytokine, and nutritional regulation of sepsis-induced increases in atrogin-1 and MuRF1 in skeletal muscleQ79143328
Burn-induced increase in atrogin-1 and MuRF-1 in skeletal muscle is glucocorticoid independent but downregulated by IGF-IQ80198869
Endotoxin disrupts the leucine-signaling pathway involving phosphorylation of mTOR, 4E-BP1, and S6K1 in skeletal muscleQ28576832
Identification of ubiquitin ligases required for skeletal muscle atrophyQ28582211
Fiber type-specific nitric oxide protects oxidative myofibers against cachectic stimuliQ33332170
Regulation of skeletal muscle protein turnover during sepsisQ33775266
CachexiaQ34061258
Role of growth hormone, insulin-like growth factor-I, and insulin-like growth factor binding proteins in the catabolic response to injury and infectionQ34601336
Regulation of muscle protein synthesis during sepsis and inflammationQ34628735
Invited Review: Autocrine/paracrine IGF-I and skeletal muscle adaptationQ34787113
Mechanisms of mortality in early and late sepsis.Q35073772
Glucocorticoids and TNFalpha interact cooperatively to mediate sepsis-induced leucine resistance in skeletal muscleQ35690899
Displacement of insulin-like growth factors from their binding proteins as a potential treatment for strokeQ35895419
IGF-I/IGFBP-3 equilibrates ratios of pro- to anti-inflammatory cytokines, which are predictors for organ function in severely burned pediatric patientsQ36088038
Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPaseQ36623662
Acute alcohol intoxication increases atrogin-1 and MuRF1 mRNA without increasing proteolysis in skeletal muscleQ36647885
Structure, Evolution, Expression and Regulation of Insulin-Like Growth Factors I and IIQ36922028
Calpain activity and muscle wasting in sepsisQ36956035
Interleukin 6 causes growth impairment in transgenic mice through a decrease in insulin-like growth factor-I. A model for stunted growth in children with chronic inflammationQ37363276
AMP-activated protein kinase agonists increase mRNA content of the muscle-specific ubiquitin ligases MAFbx and MuRF1 in C2C12 cellsQ40177203
Sepsis and septic shock--a review of laboratory models and a proposalQ40290200
Regulation and function of insulin-like growth factor-binding protein-1.Q40489943
Growth hormone and the insulin-like growth factor system in myogenesisQ41192757
Increased weight gain, nitrogen retention and muscle protein synthesis following treatment of diabetic rats with insulin-like growth factor (IGF)-I and des(1–3)IGF-IQ42861840
Lipopolysaccharide regulates proinflammatory cytokine expression in mouse myoblasts and skeletal muscleQ44107264
Acute in vivo elevation of insulin-like growth factor (IGF) binding protein-1 decreases plasma free IGF-I and muscle protein synthesisQ44559296
Differential effect of sepsis on ability of leucine and IGF-I to stimulate muscle translation initiationQ44928884
Insulin-like growth factor binding protein-1 induces insulin release in the rat.Q46030537
Effect of the glucocorticoid receptor antagonist RU 38486 on muscle protein breakdown in sepsisQ46136754
IL-6-induced skeletal muscle atrophyQ46172460
Effect of rhIL-6 infusion on GH-->IGF-I axis mediators in humansQ46180021
Protein breakdown in muscle from burned rats is blocked by insulin-like growth factor i and glycogen synthase kinase-3beta inhibitorsQ46414798
Beta-adrenergic blockade exacerbates sepsis-induced changes in tumor necrosis factor alpha and interleukin-6 in skeletal muscle and is associated with impaired translation initiationQ46732778
Why do patients with weight loss have a worse outcome when undergoing chemotherapy for gastrointestinal malignancies?Q47282777
Increased protein synthesis after acute IGF-I or insulin infusion is localized to muscle in miceQ47747685
The anti-catabolic efficacy of insulin-like growth factor-I is enhanced by its early administration to rats receiving dexamethasoneQ48009047
Work-induced growth of skeletal muscle in normal and hypophysectomized ratsQ51203334
Growth hormone and insulinlike growth factor I enhance host defense in a murine sepsis model.Q54602949
Insulinlike growth factor I plus insulinlike growth factor binding protein 3 attenuates the proinflammatory acute phase response in severely burned children.Q54602965
rhIGF-I/IGFBP-3 complex, but not free rhIGF-I, supports muscle protein biosynthesis in rats during semistarvationQ61480383
Provision of rhIGF-I/IGFBP-3 complex attenuated development of cancer cachexia in an experimental tumor modelQ62141825
Whole body protein synthesis and catabolism in septic manQ67647379
Magnitude of body-cell-mass depletion and the timing of death from wasting in AIDSQ69714256
Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic miceQ72223472
IGF-I/IGFBP-3 binary complex modulates sepsis-induced inhibition of protein synthesis in skeletal muscleQ73127330
P4510describes a project that usesImageQuantQ112270642
P433issue6
P921main subjectpreproinsulinQ7240673
sepsisQ183134
P304page(s)787-797
P577publication date2009-06-01
P1433published inMetabolismQ15764354
P1476titleLocal insulin-like growth factor I prevents sepsis-induced muscle atrophy
P478volume58