Disruption of genes encoding eIF4E binding proteins-1 and -2 does not alter basal or sepsis-induced changes in skeletal muscle protein synthesis in male or female mice

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Disruption of genes encoding eIF4E binding proteins-1 and -2 does not alter basal or sepsis-induced changes in skeletal muscle protein synthesis in male or female mice is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...999582S
P356DOI10.1371/JOURNAL.PONE.0099582
P932PMC publication ID4063727
P698PubMed publication ID24945486
P5875ResearchGate publication ID263297413

P2093author name stringScot R Kimball
Charles H Lang
Jennifer L Steiner
Anne M Pruznak
Gina Deiter
Maithili Navaratnarajah
Lydia Kutzler
P2860cites workNovel events in the molecular regulation of muscle mass in critically ill patients.Q54582240
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Hormone, cytokine, and nutritional regulation of sepsis-induced increases in atrogin-1 and MuRF1 in skeletal muscleQ79143328
Animal research. Harmonization of animal care and use guidanceQ83289343
4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein familyQ24318361
Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap functionQ24324452
Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4EQ24597361
A novel mTOR-regulated phosphorylation site in elongation factor 2 kinase modulates the activity of the kinase and its binding to calmodulinQ24599904
A novel function of the MA-3 domains in transformation and translation suppressor Pdcd4 is essential for its binding to eukaryotic translation initiation factor 4AQ24623285
Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucineQ24633679
Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2Q28511429
Identification of Ubiquitin Ligases Required for Skeletal Muscle AtrophyQ28582211
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathwayQ29620730
Pathophysiologic response to severe burn injuryQ33369410
Olanzapine promotes fat accumulation in male rats by decreasing physical activity, repartitioning energy and increasing adipose tissue lipogenesis while impairing lipolysis.Q33942644
Age and tissue specific differences in the development of acute insulin resistance following injuryQ34089832
BCATm deficiency ameliorates endotoxin-induced decrease in muscle protein synthesis and improves survival in septic mice.Q34150233
Delayed Recovery of Skeletal Muscle Mass following Hindlimb Immobilization in mTOR Heterozygous MiceQ34321178
Nutrient signaling to mTOR and cell growthQ34331244
Sepsis-induced alterations in protein-protein interactions within mTOR complex 1 and the modulating effect of leucine on muscle protein synthesisQ34372599
Cancer Cachexia: Traditional Therapies and Novel Molecular Mechanism-Based Approaches to TreatmentQ34470745
Sepsis-induced suppression of skeletal muscle translation initiation mediated by tumor necrosis factor alphaQ34589839
Alterations of protein turnover underlying disuse atrophy in human skeletal muscle.Q34609987
Synergistic activation of eIF4A by eIF4B and eIF4G.Q34779422
Ethyl Pyruvate Preserves IGF-I Sensitivity toward mTOR Substrates and Protein Synthesis in C2C12 MyotubesQ35558447
Glucocorticoids and TNFalpha interact cooperatively to mediate sepsis-induced leucine resistance in skeletal muscleQ35690899
Endotoxin and interferon-gamma inhibit translation in skeletal muscle cells by stimulating nitric oxide synthase activityQ35880345
Role of p70S6K1-mediated Phosphorylation of eIF4B and PDCD4 Proteins in the Regulation of Protein SynthesisQ36466762
The Insulin-Induced Signalling Pathway Leading to S6 and Initiation Factor 4E Binding Protein 1 Phosphorylation Bifurcates at a Rapamycin-Sensitive Point Immediately Upstream of p70s6kQ36572099
mTor Signaling in Skeletal Muscle During Sepsis and Inflammation: Where Does It All Go Wrong?Q36711877
Protein kinase B/Akt: a nexus of growth factor and cytokine signaling in determining muscle massQ36749035
Calpain activity and muscle wasting in sepsisQ36956035
Sepsis and AMPK Activation by AICAR Differentially Regulate FoxO-1, -3 and -4 mRNA in Striated MuscleQ37000179
Assessing effects of alcohol consumption on protein synthesis in striated musclesQ37120412
Local insulin-like growth factor I prevents sepsis-induced muscle atrophyQ37381871
Sepsis-induced myopathyQ37666348
Quantification of lean tissue losses during cancer and HIV infection/AIDSQ37854355
Mechanisms regulating skeletal muscle growth and atrophyQ38091731
A class IA PI3K controls inflammatory cytokine production in human neutrophilsQ39563488
Nutritional care of the injured and/or septic patientQ40783108
Sepsis-induced muscle growth hormone resistance occurs independently of STAT5 phosphorylationQ42438472
TNFalpha mediates sepsis-induced impairment of basal and leucine-stimulated signaling via S6K1 and eIF4E in cardiac muscleQ42470333
Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1.Q42511063
Blocking eukaryotic initiation factor 4F complex formation does not inhibit the mTORC1-dependent activation of protein synthesis in cardiomyocytesQ46202292
Implications of critical illness, injury, and sepsis on lean body mass and nutritional needsQ47912195
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectsepsisQ183134
P304page(s)e99582
P577publication date2014-06-19
P1433published inPLOS OneQ564954
P1476titleDisruption of genes encoding eIF4E binding proteins-1 and -2 does not alter basal or sepsis-induced changes in skeletal muscle protein synthesis in male or female mice
P478volume9

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cites work (P2860)
Q927113004E-BP1 and 4E-BP2 double knockout mice are protected from aging-associated sarcopenia
Q55209127Effects of single amino acid deficiency on mRNA translation are markedly different for methionine versus leucine.
Q37419009Marginal dietary zinc deprivation augments sepsis-induced alterations in skeletal muscle TNF-α but not protein synthesis
Q49164095MiR-22-3p Regulates Cell Proliferation and Inhibits Cell Apoptosis through Targeting the eIF4EBP3 Gene in Human Cervical Squamous Carcinoma Cells
Q46360777Muscle metabolic alterations induced by genetic ablation of 4E-BP1 and 4E-BP2 in response to diet-induced obesity
Q90580459RNA processing in skeletal muscle biology and disease
Q35177499Sepsis attenuates the anabolic response to skeletal muscle contraction
Q47294293Temporally Distinct Regulation of Pathways Contributing to Cardiac Proteostasis During the Acute and Recovery Phases of Sepsis

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