| scholarly article | Q13442814 |
| P50 | author | George Thomas | Q55293017 |
| P2093 | author name string | Stephen G Dann | |
| P2860 | cites work | Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex | Q24295120 |
| mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery | Q24302549 | ||
| Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action | Q24302566 | ||
| Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase. | Q24535599 | ||
| Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development | Q24563399 | ||
| mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells | Q24564276 | ||
| Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases | Q24599204 | ||
| Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway | Q24643816 | ||
| RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1 | Q24682697 | ||
| eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation | Q27860920 | ||
| LST8 negatively regulates amino acid biosynthesis as a component of the TOR pathway | Q27930185 | ||
| The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine | Q27930850 | ||
| RTG-dependent mitochondria to nucleus signaling is negatively regulated by the seven WD-repeat protein Lst8p | Q27934646 | ||
| Mks1 in concert with TOR signaling negatively regulates RTG target gene expression in S. cerevisiae | Q27939752 | ||
| The Saccharomyces cerevisiae Rheb G-protein is involved in regulating canavanine resistance and arginine uptake | Q27940029 | ||
| Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae | Q27940050 | ||
| Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p | Q27940169 | ||
| GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR | Q28115142 | ||
| TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling | Q28131740 | ||
| Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults | Q28131763 | ||
| Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro | Q28138191 | ||
| Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins | Q28207283 | ||
| Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells | Q28207586 | ||
| Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site | Q28210107 | ||
| The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses | Q28240102 | ||
| PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase | Q28244045 | ||
| Rheb binds and regulates the mTOR kinase | Q28247033 | ||
| Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency | Q28249019 | ||
| mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes | Q42809294 | ||
| Regulation of leucine uptake by tor1+ in Schizosaccharomyces pombe is sensitive to rapamycin | Q43275098 | ||
| Quick guide: target of rapamycin | Q43967600 | ||
| Signalling pathways and combinatory effects of insulin and amino acids in isolated rat hepatocytes | Q44086589 | ||
| Rheb is an essential regulator of S6K in controlling cell growth in Drosophila | Q44453753 | ||
| Amino Acids and Insulin Control Autophagic Proteolysis through Different Signaling Pathways in Relation to mTOR in Isolated Rat Hepatocytes | Q44650510 | ||
| Tsc1+ and tsc2+ regulate arginine uptake and metabolism in Schizosaccharomyces pombe | Q44725308 | ||
| An activated mTOR mutant supports growth factor-independent, nutrient-dependent cell survival | Q44888568 | ||
| The mTOR signaling pathway mediates control of ribosomal protein mRNA translation in rat liver | Q45020034 | ||
| Tor signaling and nutrient-based signals converge on Mks1p phosphorylation to regulate expression of Rtg1.Rtg3p-dependent target genes | Q45028059 | ||
| Nutrient sensor links obesity with diabetes risk | Q45086880 | ||
| Whole body protein breakdown is less inhibited by insulin, but still responsive to amino acid, in nondiabetic elderly subjects | Q45173604 | ||
| PAT-related amino acid transporters regulate growth via a novel mechanism that does not require bulk transport of amino acids | Q46447985 | ||
| Retrograde response to mitochondrial dysfunction is separable from TOR1/2 regulation of retrograde gene expression | Q46777999 | ||
| A nutrient sensor mechanism controls Drosophila growth. | Q47070296 | ||
| Leucine-specific binding of photoreactive Leu7-MAP to a high molecular weight protein on the plasma membrane of the isolated rat hepatocyte | Q47370654 | ||
| Insulin receptor substrate 1 and 2 (IRS1 and IRS2): what a tangled web we weave | Q47986253 | ||
| The Rapamycin and FKBP12 Target (RAFT) Displays Phosphatidylinositol 4-Kinase Activity | Q57371739 | ||
| Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex | Q28273915 | ||
| Upstream and downstream of mTOR | Q28277365 | ||
| Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast | Q28277565 | ||
| SKAR is a specific target of S6 kinase 1 in cell growth control | Q28280086 | ||
| p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD | Q28592766 | ||
| Tuberous sclerosis complex tumor suppressor-mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent | Q28593855 | ||
| Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha | Q28616168 | ||
| Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity | Q29614241 | ||
| The TOR pathway: a target for cancer therapy | Q29614242 | ||
| Amino Acid Sufficiency and mTOR Regulate p70 S6 Kinase and eIF-4E BP1 through a Common Effector Mechanism | Q29614737 | ||
| Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms | Q29615455 | ||
| Genetics: influence of TOR kinase on lifespan in C. elegans | Q29616619 | ||
| Akt regulates growth by directly phosphorylating Tsc2 | Q29620397 | ||
| Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin | Q29620399 | ||
| Exogenous Amino Acids Regulate Trophectoderm Differentiation in the Mouse Blastocyst through an mTOR-Dependent Pathway | Q30308510 | ||
| Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase | Q33890035 | ||
| Branched-chain amino acids increase p70S6k phosphorylation in human skeletal muscle after resistance exercise | Q33976354 | ||
| RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to formation of yeast prion [URE3] | Q34011717 | ||
| Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase. | Q34063643 | ||
| Rheb promotes cell growth as a component of the insulin/TOR signalling network | Q34199893 | ||
| L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors | Q34497164 | ||
| Mammalian TOR: A Homeostatic ATP Sensor | Q34519173 | ||
| Increased uptake of amino acids and 2-deoxy-D-glucose by virus-transformed cells in culture | Q34692279 | ||
| Identification of TOR signaling complexes: more TORC for the cell growth engine | Q34952903 | ||
| Mks1p is required for negative regulation of retrograde gene expression in Saccharomyces cerevisiae but does not affect nitrogen catabolite repression-sensitive gene expression | Q35259063 | ||
| Mitochondrial signaling: the retrograde response | Q35739853 | ||
| Signaling control of mRNA translation in cancer pathogenesis | Q35750101 | ||
| Amino acid transporters ASCT2 and LAT1 in cancer: partners in crime? | Q36139606 | ||
| Bidirectional modulation of insulin action by amino acids | Q37380395 | ||
| 4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase | Q37628904 | ||
| Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake | Q39616081 | ||
| Regulation of the small GTPase Rheb by amino acids. | Q40371799 | ||
| hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase | Q40392574 | ||
| Inhibition of amino acid-mTOR signaling by a leucine derivative induces G1 arrest in Jurkat cells | Q40673162 | ||
| Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling | Q40711462 | ||
| Identification of a conserved motif required for mTOR signaling | Q40736711 | ||
| Leucine limitation induces autophagy and activation of lysosome-dependent proteolysis in C2C12 myotubes through a mammalian target of rapamycin-independent signaling pathway | Q40868615 | ||
| Structural requirement of leucine for activation of p70 S6 kinase | Q40958861 | ||
| Regulation of System A amino acid transport in L6 rat skeletal muscle cells by insulin, chemical and hyperthermic stress | Q40983592 | ||
| Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability | Q41962450 | ||
| Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes | Q42797755 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 2821-2829 | |
| P577 | publication date | 2006-05-02 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | FEBS Letters | Q1388051 |
| P1476 | title | The amino acid sensitive TOR pathway from yeast to mammals | |
| P478 | volume | 580 |
| Q37378827 | 4EBP-Dependent Signaling Supports West Nile Virus Growth and Protein Expression |
| Q33590683 | A Drosophila insulin-like peptide promotes growth during nonfeeding states |
| Q52561047 | A comparative analysis of single cell and droplet-based FACS for improving production phenotypes: Riboflavin overproduction in Yarrowia lipolytica. |
| Q33471392 | A network of conserved damage survival pathways revealed by a genomic RNAi screen. |
| Q34626081 | Activation of the mTOR signaling pathway in breast cancer MCF‑7 cells by a peptide derived from Porphyra yezoensis |
| Q52655976 | Altered peripheral amino acid profile indicate a systemic impact of active celiac disease and a possible role of amino acids in disease pathogenesis |
| Q27001717 | Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TOR |
| Q37374064 | Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling |
| Q36979733 | Amino acid transporters and nutrient-sensing mechanisms: new targets for treating insulin-linked disorders? |
| Q33279358 | Amino acids and insulin act additively to regulate components of the ubiquitin-proteasome pathway in C2C12 myotubes |
| Q38454084 | Angiotensin II blockade: how its molecular targets may signal to mitochondria and slow aging. Coincidences with calorie restriction and mTOR inhibition |
| Q36991389 | Anorexigenic and orexigenic hormone modulation of mammalian target of rapamycin complex 1 activity and the regulation of hypothalamic agouti-related protein mRNA expression. |
| Q37930526 | Autophagy and Heart Failure: A Possible Role for Homocysteine |
| Q27973709 | Autophagy in Apicomplexa: a life sustaining death mechanism? |
| Q42186548 | Autophagy in the myocardium: Dying for survival? |
| Q42583383 | Autophagy is a cell death mechanism in Toxoplasma gondii |
| Q37529825 | Autophagy: regulation and role in disease |
| Q29614476 | Bidirectional transport of amino acids regulates mTOR and autophagy |
| Q38091011 | Body size regulation and insulin-like growth factor signaling |
| Q64074224 | Cationic amino acid transporter PQLC2 is a potential therapeutic target in gastric cancer |
| Q37021691 | Changing the energy of an immune response |
| Q43147181 | Combined transcript and metabolite profiling of Arabidopsis grown under widely variant growth conditions facilitates the identification of novel metabolite-mediated regulation of gene expression |
| Q33701049 | Conservation, duplication, and loss of the Tor signaling pathway in the fungal kingdom |
| Q38268759 | Current models of mammalian target of rapamycin complex 1 (mTORC1) activation by growth factors and amino acids. |
| Q24318729 | DAP1, a novel substrate of mTOR, negatively regulates autophagy |
| Q48384252 | DREF is required for cell and organismal growth in Drosophila and functions downstream of the nutrition/TOR pathway |
| Q26766217 | Developing criteria for evaluation of geroprotectors as a key stage toward translation to the clinic |
| Q36005607 | Differential regulation of protein synthesis in skeletal muscle and liver of neonatal pigs by leucine through an mTORC1-dependent pathway |
| Q45981746 | Distinct signaling mechanisms activate the target of rapamycin in response to different B-cell stimuli. |
| Q37201338 | Drosophila expresses a CD98 transporter with an evolutionarily conserved structure and amino acid-transport properties |
| Q37524170 | Drosophila miR-277 controls branched-chain amino acid catabolism and affects lifespan. |
| Q33619056 | Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling |
| Q41426791 | Dynamics of mTORC1 activation in response to amino acids. |
| Q51623448 | Effect of dietary phytate and phytase on proteolytic digestion and growth regulation of broilers |
| Q28569842 | GADD34 mediates cytoprotective autophagy in mutant huntingtin expressing cells via the mTOR pathway |
| Q27938945 | Genomic Analysis of ATP Efflux in Saccharomyces cerevisiae |
| Q36901790 | Glutamate dehydrogenase contributes to leucine sensing in the regulation of autophagy. |
| Q34050094 | Glutamine addiction: a new therapeutic target in cancer |
| Q36046422 | Histidine Prevents Cu-Induced Oxidative Stress and the Associated Decreases in mRNA from Encoding Tight Junction Proteins in the Intestine of Grass Carp (Ctenopharyngodon idella). |
| Q42976622 | Insulin delays the progression of Drosophila cells through G2/M by activating the dTOR/dRaptor complex |
| Q46411882 | Involvement of insulin in early development of mouse one-cell stage embryos |
| Q39738054 | L-Proline induces differentiation of ES cells: a novel role for an amino acid in the regulation of pluripotent cells in culture |
| Q45045040 | Leucine-stimulated mTOR signaling is partly attenuated in skeletal muscle of chronically uremic rats |
| Q40002274 | Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis |
| Q39690739 | Lovastatin inhibits EGFR dimerization and AKT activation in squamous cell carcinoma cells: potential regulation by targeting rho proteins |
| Q33803746 | MAP4K3 is a component of the TORC1 signalling complex that modulates cell growth and viability in Drosophila melanogaster. |
| Q36741548 | Mammalian target of rapamycin contributes to the acquired apoptotic resistance of human mesothelioma multicellular spheroids |
| Q37377388 | Methionine Regulates mTORC1 via the T1R1/T1R3-PLCβ-Ca2+-ERK1/2 Signal Transduction Process in C2C12 Cells |
| Q33288114 | Molecular determinants of caste differentiation in the highly eusocial honeybee Apis mellifera |
| Q41953543 | Notch-induced T cell development requires phosphoinositide-dependent kinase 1. |
| Q42146110 | Nutrient/TOR-dependent regulation of RNA polymerase III controls tissue and organismal growth in Drosophila. |
| Q37896509 | PI3 Kinase regulation of neural regeneration and muscle hypertrophy after spinal cord injury |
| Q43021296 | Physiology. Food as a hormone. |
| Q35652261 | Point mutations in TOR confer Rheb-independent growth in fission yeast and nutrient-independent mammalian TOR signaling in mammalian cells |
| Q92239674 | Polyamines - A New Metabolic Switch: Crosstalk With Networks Involving Senescence, Crop Improvement, and Mammalian Cancer Therapy |
| Q37872280 | Progress in the Design and Development of Phosphoinositide 3-Kinase (PI3K) Inhibitors for the Treatment of Chronic Diseases |
| Q36605975 | Quantitative and evolutionary biology of alternative splicing: how changing the mix of alternative transcripts affects phenotypic plasticity and reaction norms |
| Q35676903 | RalA functions as an indispensable signal mediator for the nutrient-sensing system |
| Q38868037 | Reduced TORC1 signaling abolishes mitochondrial dysfunctions and shortened chronological lifespan of Isc1p-deficient cells |
| Q50975667 | Regulation in free amino acid profile and protein synthesis pathway of growing pig skeletal muscles by low-protein diets for different time periods. |
| Q38216365 | Regulation of autophagy by amino acids and MTOR-dependent signal transduction |
| Q34628735 | Regulation of muscle protein synthesis during sepsis and inflammation |
| Q35114422 | Regulation of protein synthesis by amino acids in muscle of neonates |
| Q37212205 | Replicative aging in yeast: the means to the end |
| Q42719842 | Responses to nutrients in farm animals: implications for production and quality |
| Q38200018 | Role of AMP-activated protein kinase in cancer therapy |
| Q24303889 | Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway |
| Q53940416 | Role of amino acid transporter LAT2 in the activation of mTORC1 pathway and the pathogenesis of crescentic glomerulonephritis |
| Q38075282 | Sensing the immune microenvironment to coordinate T cell metabolism, differentiation & function. |
| Q34117251 | Sensitivity of global translation to mTOR inhibition in REN cells depends on the equilibrium between eIF4E and 4E-BP1. |
| Q53459071 | Single yeast cells vary in transcription activity not in delay time after a metabolic shift |
| Q43078177 | Stress-responsive Gln3 localization in Saccharomyces cerevisiae is separable from and can overwhelm nitrogen source regulation |
| Q51315166 | Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling. |
| Q37325875 | Techniques to study autophagy in plants |
| Q47629815 | Telmisartan inhibits hepatocellular carcinoma cell proliferation in vitro by inducing cell cycle arrest |
| Q37267639 | The Drosophila deoxyhypusine hydroxylase homologue nero and its target eIF5A are required for cell growth and the regulation of autophagy. |
| Q41851530 | The angiotensin II type 1 receptor antagonist telmisartan inhibits cell proliferation and tumor growth of esophageal adenocarcinoma via the AMPKα/mTOR pathway in vitro and in vivo |
| Q24627306 | The mTOR Signalling Pathway in Human Cancer |
| Q39643259 | The mammalian target of rapamycin inhibitor RAD001 (everolimus) synergizes with chemotherapeutic agents, ionizing radiation and proteasome inhibitors in pre-B acute lymphocytic leukemia |
| Q36513197 | The mechanism of mTOR (mammalian target of rapamycin) in a mouse model of polycystic ovary syndrome (PCOS). |
| Q42206698 | The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1. |
| Q37824183 | The regulation of autophagy – unanswered questions |
| Q36465061 | Tor1 regulates protein solubility in Saccharomyces cerevisiae |
| Q24645458 | Trading translation with RNA-binding proteins |
| Q38985660 | West nile virus-induced activation of mammalian target of rapamycin complex 1 supports viral growth and viral protein expression |
| Q34194276 | Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level |
| Q35696480 | l-Leucine Alters Pancreatic β-Cell Differentiation and Function via the mTor Signaling Pathway |
| Q29617214 | mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex |
| Q36156171 | mTOR is the rapamycin-sensitive kinase that confers mechanically-induced phosphorylation of the hydrophobic motif site Thr(389) in p70(S6k) |
| Q61807513 | mTOR: A Cellular Regulator Interface in Health and Disease |
| Q36697506 | mTOR: A Link from the Extracellular Milieu to Transcriptional Regulation of Oligodendrocyte Development |
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