Attenuation of the macrophage inflammatory activity by TiO₂ nanotubes via inhibition of MAPK and NF-κB pathways

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Attenuation of the macrophage inflammatory activity by TiO₂ nanotubes via inhibition of MAPK and NF-κB pathways is …
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scholarly articleQ13442814

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P356DOI10.2147/IJN.S92019
P932PMC publication ID4608594
P698PubMed publication ID26491301

P50authorPatrik SchmukiQ68712422
Anca MazareQ42151358
P2093author name stringAnisoara Cimpean
Patricia Neacsu
P2860cites workOne-Dimensional Titanium Dioxide Nanomaterials: NanotubesQ61206054
The p38 mitogen-activated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP)Q73083269
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Effects of TiO2 nanotubes with different diameters on gene expression and osseointegration of implants in minipigsQ84512653
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PKC- and ERK-dependent activation of I kappa B kinase by lipopolysaccharide in macrophages: enhancement by P2Y receptor-mediated CaMK activationQ28362742
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Luteolin inhibits an endotoxin-stimulated phosphorylation cascade and proinflammatory cytokine production in macrophagesQ31726526
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Ikarisoside A inhibits inducible nitric oxide synthase in lipopolysaccharide-stimulated RAW 264.7 cells via p38 kinase and nuclear factor-kappaB signaling pathwaysQ38498379
Reduced adhesion of macrophages on anodized titanium with select nanotube surface featuresQ38608033
Nanochannels formed on TiZr alloy improve biological responseQ38862042
Reduced inflammatory activity of RAW 264.7 macrophages on titania nanotube modified Ti surfaceQ38956664
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Wedelolactone inhibits LPS-induced pro-inflammation via NF-kappaB pathway in RAW 264.7 cellsQ39068343
Aloe vera downregulates LPS-induced inflammatory cytokine production and expression of NLRP3 inflammasome in human macrophagesQ39116221
6-Acetonyl-5,6-dihydrosanguinarine (ADS) from Chelidonium majus L. triggers proinflammatory cytokine production via ROS-JNK/ERK-NFκB signaling pathwayQ39154227
Anti-inflammatory effects of saponins derived from the roots of Platycodon grandiflorus in lipopolysaccharide‑stimulated BV2 microglial cellsQ39170115
Anti-inflammatory effect of essential oil and its constituents from fingered citron (Citrus medica L. var. sarcodactylis) through blocking JNK, ERK and NF-κB signaling pathways in LPS-activated RAW 264.7 cells.Q39173706
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BDMC33, A curcumin derivative suppresses inflammatory responses in macrophage-like cellular system: role of inhibition in NF-κB and MAPK signaling pathwaysQ39367047
Regulation of inflammatory cytokines in lipopolysaccharide-stimulated RAW 264.7 murine macrophage by 7-O-methyl-naringenin.Q39375214
The effect of surface topography on early NFκB signaling in macrophagesQ39658242
Anti-inflammatory activity of 4-methoxyhonokiol is a function of the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-kappaB, JNK and p38 MAPK inactivationQ39996765
Tanshinone IIA inhibits LPS-induced NF-kappaB activation in RAW 264.7 cells: possible involvement of the NIK-IKK, ERK1/2, p38 and JNK pathwaysQ40263291
Triptolide inhibits murine-inducible nitric oxide synthase expression by down-regulating lipopolysaccharide-induced activity of nuclear factor-kappa B and c-Jun NH2-terminal kinaseQ40546139
Inhibition of p38 and ERK MAP kinases blocks endotoxin-induced nitric oxide production and differentially modulates cytokine expressionQ40582812
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IFN-gamma + LPS induction of iNOS is modulated by ERK, JNK/SAPK, and p38(mapk) in a mouse macrophage cell lineQ40828168
Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subverQ40913997
Involvement of p38 mitogen-activated protein kinase in lipopolysaccharide-induced iNOS and COX-2 expression in J774 macrophagesQ40935358
Role of CSB/p38/RK stress response kinase in LPS and cytokine signaling mechanismsQ40971614
The IkappaBalpha/NF-kappaB complex has two hot spots, one at either end of the interfaceQ41492776
Potential role of the JNK/SAPK signal transduction pathway in the induction of iNOS by TNF-alphaQ42536527
Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in macrophagesQ43429525
In vitro inflammatory response of nanostructured titania, silicon oxide, and polycaprolactone.Q46479230
6-(Methylsulfinyl)hexyl isothiocyanate suppresses inducible nitric oxide synthase expression through the inhibition of Janus kinase 2-mediated JNK pathway in lipopolysaccharide-activated murine macrophagesQ46684027
Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 in lipopolysaccharide-stimulated RAW264.7 cells by carboxybutyrylated glucosamine takes place via down-regulation of mitogen-activated protein kinase-mediated nuclear factor-kappaB sQ46800724
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
P304page(s)6455-6467
P577publication date2015-10-12
P1433published inInternational Journal of NanomedicineQ6051502
P1476titleAttenuation of the macrophage inflammatory activity by TiO₂ nanotubes via inhibition of MAPK and NF-κB pathways
P478volume10

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cites work (P2860)
Q60947955Anti-Inflammatory Activity of Leaf Extract via Modulating NF-κB and p38/JNK Pathways
Q90229919Lateral Spacing of TiO2 Nanotubes Modulates Osteoblast Behavior
Q41430394Metformin Inhibits Advanced Glycation End Products-Induced Inflammatory Response in Murine Macrophages Partly through AMPK Activation and RAGE/NFκB Pathway Suppression.
Q60912597Nanotubular TiO regulates macrophage M2 polarization and increases macrophage secretion of VEGF to accelerate endothelialization via the ERK1/2 and PI3K/AKT pathways
Q60307539Surface nanocavitation of titanium modulates macrophage activity
Q91845408Titanium Dioxide Nanotube Arrays for Cardiovascular Stent Applications

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