Evaluation of PTEN immunoexpression in oral submucous fibrosis: role in pathogenesis and malignant transformation

scientific article

Evaluation of PTEN immunoexpression in oral submucous fibrosis: role in pathogenesis and malignant transformation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12105-012-0341-Z
P932PMC publication ID3422583
P698PubMed publication ID22392409
P5875ResearchGate publication ID221889999

P2093author name stringPunnya V Angadi
Rekha Krishnapillai
P2860cites workInhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTENQ24322051
PTEN function: how normal cells control it and tumour cells lose itQ24528114
The biology and clinical relevance of the PTEN tumor suppressor pathwayQ28272157
Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinomaQ33341180
Potentially malignant disorders of the oral and oropharyngeal mucosa; terminology, classification and present concepts of managementQ33357133
PTEN expression is down-regulated in liver tissues of rats with hepatic fibrosis induced by biliary stenosisQ33496299
PTEN, a unique tumor suppressor geneQ33974014
Role of areca nut consumption in the cause of oral cancers. A cytogenetic assessmentQ34322667
Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosisQ34371260
Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10)Q34533889
Dihydrosphingosine 1-phosphate has a potent antifibrotic effect in scleroderma fibroblasts via normalization of phosphatase and tensin homolog levelsQ34555185
TGF-beta-induced EMT: mechanisms and implications for fibrotic lung diseaseQ34581113
Diagnosis of premalignant endometrial diseaseQ35586140
Molecular pathogenesis of oral submucous fibrosis--a collagen metabolic disorderQ36157193
Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathwaysQ36256326
Oral submucous fibrosis: review on aetiology and pathogenesisQ36323909
Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosisQ36742285
The role of epithelial-mesenchymal transition in oral squamous cell carcinoma and oral submucous fibrosisQ36835159
Head and neck cancer in the betel quid chewing area: recent advances in molecular carcinogenesisQ37255286
Global epidemiology of oral and oropharyngeal cancerQ37274268
Phosphatase and tensin homologue deleted on chromosome 10: extending its PTENtaclesQ37308049
TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTENQ37347217
Oral squamous cell carcinoma overviewQ37403122
Loss of PTEN expression as a prognostic marker for tongue cancerQ38458513
p53 aberrations in oral submucous fibrosis and oral squamous cell carcinoma detected by immunocytochemistry and PCR-SSCP.Q38472455
Immunohistochemical evidence of PTEN in oral squamous cell carcinoma and its correlation with the histological malignancy grading systemQ40634516
Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase.Q42435832
Assessment of malignant potential of oral submucous fibrosis through evaluation of p63, E-cadherin and CD105 expressionQ42477611
Expression of proliferating cell nuclear antigen (PCNA) in oral submucous fibrosis, oral epithelial hyperkeratosis and oral epithelial dysplasia in TaiwanQ42490777
Epithelial growth fraction and expression of p53 tumour suppressor gene in oral submucous fibrosisQ42519050
An altered keratinocyte phenotype in oral submucous fibrosis: correlation of keratin K17 expression with disease severity.Q42523805
Adenomatous polyposis coli gene mutation and decreased wild-type p53 protein expression in oral submucous fibrosis: a preliminary investigationQ43707270
Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis.Q45170033
Mutational analysis of the PTEN gene in head and neck squamous cell carcinomaQ47751177
Expression of bcl-2 and bax in chewing tobacco-induced oral cancers and oral lesions from IndiaQ50103762
Arecoline and oral keratinocytes may affect the collagen metabolism of fibroblasts.Q51751442
Homozygous deletion of the PTEN tumor-suppressor gene is not a feature in oral squamous cell carcinoma.Q52827239
Fingerprinting genomic instability in oral submucous fibrosis.Q53323980
Cytokeratin expression in oral submucous fibrosis--an immunohistochemical study.Q53350701
Malignant transformation rate in oral submucous fibrosis over a 17-year period.Q53541061
Activation of PPARdelta inhibits cardiac fibroblast proliferation and the transdifferentiation into myofibroblasts.Q53549142
Alteration and clinical relevance of PTEN expression and its correlation with survivin expression in epithelial ovarian tumors.Q53633276
Oral submucous fibrosisQ70893958
Infrequent genetic alterations of the tumor suppressor gene PTEN/MMAC1 in squamous cell carcinoma of the oral cavityQ74443207
PTEN expression and methylation status in oral squamous cell carcinomaQ81323758
[Effect of arecoline on the differentiation of myofibroblasts of oral mucosa]Q81501366
PTEN as a new agent in the fight against fibrogenesisQ82040417
Evaluation of myofibroblasts in oral submucous fibrosis: correlation with disease severityQ83098482
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectoral submucous fibrosisQ7099404
P304page(s)314-321
P577publication date2012-03-06
P1433published inHead and Neck PathologyQ15816982
P1476titleEvaluation of PTEN immunoexpression in oral submucous fibrosis: role in pathogenesis and malignant transformation
P478volume6

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cites work (P2860)
Q92272599CD1a+ and CD207+ cells are reduced in oral submucous fibrosis and oral squamous cell carcinoma
Q58129865Cancer driver mutations in endometriosis: Variations on the major theme of fibrogenesis
Q38433013Identification of oral cancer related candidate genes by integrating protein-protein interactions, gene ontology, pathway analysis and immunohistochemistry.
Q37480360Immunohistochemical expression of phosphatase and tensin homolog in histologic gradings of oral squamous cell carcinoma
Q39667374Involvement of IGF-2, IGF-1R, IGF-2R and PTEN in development of human tooth germ - an immunohistochemical study
Q91296617Loss of heterozygosity and immunoexpression of PTEN in oral epithelial dysplasia and squamous cell carcinoma
Q39229606Oral submucous fibrosis: An update on pathophysiology of malignant transformation
Q98893356Signaling pathways promoting epithelial mesenchymal transition in oral submucous fibrosis and oral squamous cell carcinoma

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