Ethanol Reversal of Tolerance to the Respiratory Depressant Effects of Morphine

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Ethanol Reversal of Tolerance to the Respiratory Depressant Effects of Morphine is …
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scholarly articleQ13442814

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P356DOI10.1038/NPP.2015.201
P932PMC publication ID4610039
P698PubMed publication ID26171718
P5875ResearchGate publication ID280125266

P50authorChris BaileyQ60062021
Rob HillQ63697060
Matthew HickmanQ37828999
Anne Lingford-HughesQ41330622
P2093author name stringGraeme Henderson
Eamonn Kelly
Yvonne Kershaw
Joanne Roberts
Abi Lyndon
John MacLachlan
Sarah Withey
P2860cites workMechanisms of fatal opioid overdoseQ33856907
The role of ethanol in heroin deathsQ71832014
Acute dependence on, but not tolerance to, heroin and morphine as measured by respiratory effects in rhesus monkeysQ73901708
Methadone: does it really have low efficacy at micro-opioid receptors?Q94695438
Species difference of site-selective glucuronidation of morphineQ46396285
Does alcohol increase the risk of overdose death: the need for a translational approachQ46657384
Ultradian corticosterone secretion is maintained in the absence of circadian cuesQ47353073
Monoacylglycerol lipase inhibition-induced changes in plasma corticosterone levels, anxiety and locomotor activity in male CD1 miceQ48030493
Alterations in the antagonism by naloxone of morphine-induced respiratory depression and analgesia after morphine pretreatmentQ48141972
London audit of drug-related overdose deaths: characteristics and typology, and implications for prevention and monitoringQ48597313
Interaction of alcohols and anesthetics with protein kinase Calpha.Q51546231
Ventilation in morphine-maintained rhesus monkeys. II: Tolerance to the antinociceptive but not the ventilatory effects of morphine.Q53703845
The role of ethanol abuse in the etiology of heroin-related deathQ68897881
Differential development of acute tolerance to analgesia, respiratory depression, gastrointestinal transit and hormone release in a morphine infusion modelQ69360245
Chronic ethanol consumption in rats produces opioid antinociceptive tolerance through inhibition of mu opioid receptor endocytosisQ33908225
Activation of protein kinase C (PKC)α or PKCε as an approach to increase morphine tolerance in respiratory depression and lethal overdoseQ34121723
Risk of death during and after opiate substitution treatment in primary care: prospective observational study in UK General Practice Research DatabaseQ34246166
BAP updated guidelines: evidence-based guidelines for the pharmacological management of substance abuse, harmful use, addiction and comorbidity: recommendations from BAP.Q34277168
μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalizationQ34310081
Agonist-selective mechanisms of GPCR desensitizationQ34722029
National record linkage study of mortality for a large cohort of opioid users ascertained by drug treatment or criminal justice sources in England, 2005-2009.Q34959778
Epidemiologic trends and geographic patterns of fatal opioid intoxications in Connecticut, USA: 1997-2007.Q34984833
Heroin overdose: research and evidence-based interventionQ35147553
Acute ethanol exposure prevents PMA-mediated augmentation of N-methyl-D-aspartate receptor function in primary cultured cerebellar granule cellsQ35159678
Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Q36591603
Mortality among people who inject drugs: a systematic review and meta-analysisQ36706977
Reversal of morphine analgesic tolerance by ethanol in the mouse.Q36852601
Ethanol reversal of cellular tolerance to morphine in rat locus coeruleus neuronsQ37027080
Mechanisms of locomotor sensitization to drugs of abuse in a two-injection protocol.Q37479889
Involvement of PKC alpha and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of mu-opioid receptors in mature brain neurons.Q37481307
BuprenorphineQ39494290
Ethanol regulation of D(1) dopamine receptor signaling is mediated by protein kinase C in an isozyme-specific mannerQ40010936
Alcohol regulates eukaryotic elongation factor 2 phosphorylation via an AMP-activated protein kinase-dependent mechanism in C2C12 skeletal myocytesQ40197427
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor geneQ41157124
Role of protein kinase C and mu-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons.Q41531803
Recovery from mu-opioid receptor desensitization after chronic treatment with morphine and methadoneQ41891627
Long-term mortality and causes of death among hospitalized Swedish drug usersQ42232912
Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.Q42528174
Effects of Animal Care Procedures on Plasma Corticosterone Levels in Group-Housed Mice during the Nocturnal Active PhaseQ42844243
Unintentional drug overdose death trends in New Mexico, USA, 1990-2005: combinations of heroin, cocaine, prescription opioids and alcoholQ43440972
Effect of ethanol self-administration on mu- and delta-opioid receptor-mediated G-protein activityQ44015282
Hair morphine concentrations of fatal heroin overdose cases and living heroin usersQ44080578
Prolonged reversal of morphine tolerance with no reversal of dependence by protein kinase C inhibitorsQ44239965
Effect of chronic ethanol and withdrawal on the mu-opioid receptor- and 5-Hydroxytryptamine(1A) receptor-stimulated binding of [(35)S]Guanosine-5'-O-(3-thio)triphosphate in the fawn-hooded rat brain: A quantitative autoradiography studyQ44330902
Protein kinase C-mediated acute tolerance to peripheral mu-opioid analgesia in the bradykinin-nociception test in miceQ44331215
How important is protein kinase C in mu-opioid receptor desensitization and morphine tolerance?Q44332145
Comparison of morphine-6-glucuronide and morphine on respiratory depressant and antinociceptive responses in wild type and mu-opioid receptor deficient miceQ44343619
Chronic ethanol consumption reduces delta-and mu-opioid receptor-stimulated G-protein coupling in rat brainQ44344324
Use of morphine and 6-monoacetylmorphine in blood for the evaluation of possible risk factors for sudden death in 192 heroin usersQ44373618
Cross-sensitization between the locomotor stimulant effects of ethanol and those of morphine and cocaine in miceQ44414841
Determination of the role of conventional, novel and atypical PKC isoforms in the expression of morphine tolerance in miceQ44923198
Continuous morphine produces more tolerance than intermittent or acute treatmentQ46106320
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectmorphineQ81225
P304page(s)762-773
P577publication date2015-07-14
P1433published inNeuropsychopharmacologyQ2261280
P1476titleEthanol Reversal of Tolerance to the Respiratory Depressant Effects of Morphine
P478volume41

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cites work (P2860)
Q44334091Commentary on Cousins et al. (2016): Accumulating evidence on risk of mortality on and off opioid substitution treatment
Q44350406Desensitization and tolerance of mu opioid receptors on pontine Kolliker-Fuse neurons
Q44343100Does exposure to opioid substitution treatment in prison reduce the risk of death after release? A national prospective observational study in England.
Q44342944Effect of Tamoxifen and Brain-Penetrant Protein Kinase C and c-Jun N-Terminal Kinase Inhibitors on Tolerance to Opioid-Induced Respiratory Depression in Mice.
Q54125167Ethanol Reversal of Oxycodone Tolerance in Dorsal Root Ganglia Neurons.
Q45057775Ethanol Reversal of Tolerance to the Antinociceptive Effects of Oxycodone and Hydrocodone
Q90968345Global patterns of opioid use and dependence: harms to populations, interventions, and future action
Q89690415Morphine-induced respiratory depression is independent of β-arrestin2 signalling
Q54119525Oxycodone-induced tolerance to respiratory depression: reversal by ethanol, pregabalin and protein kinase C inhibition.
Q39221067Oxytocin and opioid addiction revisited: old drug, new applications.
Q93085569Perioperative opioid analgesia-when is enough too much? A review of opioid-induced tolerance and hyperalgesia
Q42003859Reversal of oxycodone and hydrocodone tolerance by diazepam
Q38792361Risk to heroin users of polydrug use of pregabalin or gabapentin
Q52308788Substitution treatment in addiction: there is more than one way...
Q52628758The novel μ-opioid receptor agonist PZM21 depresses respiration and induces tolerance to antinociception.
Q99633264Tolerance to opioid-induced respiratory depression in chronic high-dose opioid users: a model-based comparison with opioid-naïve individuals

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