Age-dependent requirement of AKAP150-anchored PKA and GluR2-lacking AMPA receptors in LTP.

scientific article

Age-dependent requirement of AKAP150-anchored PKA and GluR2-lacking AMPA receptors in LTP. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SJ.EMBOJ.7601884
P932PMC publication ID2099463
P698PubMed publication ID17972919
P5875ResearchGate publication ID5873274

P2093author name stringDuane D Hall
Johannes W Hell
Yuan Lu
Robert F Dallapiazza
Yuriy M Usachev
G Stanley McKnight
Margaret Allen
Amy R Halt
Michael Weisenhaus
P2860cites workRegulation of NMDA receptors by an associated phosphatase-kinase signaling complexQ22010193
LTP and LTDQ22337342
PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking.Q27863894
Phosphorylation of the AMPA receptor subunit GluR2 differentially regulates its interaction with PDZ domain-containing proteinsQ28139757
Synapse-associated protein 97 selectively associates with a subset of AMPA receptors early in their biosynthetic pathwayQ28188399
AKAP mediated signal transductionQ28216386
SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunitQ28277480
Postsynaptic cAMP pathway gates early LTP in hippocampal CA1 regionQ28292471
A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-AQ28513233
Binding of protein phosphatase 2A to the L-type calcium channel Cav1.2 next to Ser1928, its main PKA site, is critical for Ser1928 dephosphorylationQ28566720
Miniature neurotransmission stabilizes synaptic function via tonic suppression of local dendritic protein synthesis.Q46267461
Conservation of glutamate receptor 2-containing AMPA receptors during long-term potentiationQ46269497
Calcium-permeable AMPA receptor plasticity is mediated by subunit-specific interactions with PICK1 and NSF.Q46410226
Comparison of two forms of long-term potentiation in single hippocampal neuronsQ46461855
Adaptation to synaptic inactivity in hippocampal neuronsQ46616710
Extrasynaptic membrane trafficking regulated by GluR1 serine 845 phosphorylation primes AMPA receptors for long-term potentiationQ46792274
Glutamate receptor exocytosis and spine enlargement during chemically induced long-term potentiation.Q46947126
Protein kinase A regulates calcium permeability of NMDA receptors.Q46987195
Long-term enhancement of CA1 synaptic transmission is due to increased quantal size, not quantal contentQ47437894
Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP.Q47955993
Anchoring of protein kinase A is required for modulation of AMPA/kainate receptors on hippocampal neuronsQ48137676
Parallel kinase cascades are involved in the induction of LTP at hippocampal CA1 synapsesQ48179139
Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learningQ48189640
Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neuronsQ48267434
Compartmentalized Ca(2+) channel regulation at divergent mossy-fiber release sites underlies target cell-dependent plasticityQ48377511
Maintenance of late-phase LTP is accompanied by PKA-dependent increase in AMPA receptor synthesisQ48404911
RGS2 determines short-term synaptic plasticity in hippocampal neurons by regulating Gi/o-mediated inhibition of presynaptic Ca2+ channelsQ48430469
Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurinQ48519197
Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiationQ48596002
Cocaine triggered AMPA receptor redistribution is reversed in vivo by mGluR-dependent long-term depression.Q48596022
Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons.Q49058722
Genetic and pharmacological demonstration of differential recruitment of cAMP-dependent protein kinases by synaptic activityQ49162458
Changes in paired-pulse facilitation suggest presynaptic involvement in long-term potentiation.Q52056856
Co-regulation of long-term potentiation and experience-dependent synaptic plasticity in visual cortex by age and experience.Q52208326
Deletion of type IIalpha regulatory subunit delocalizes protein kinase A in mouse sperm without affecting motility or fertilization.Q52536028
Intracellular spermine confers rectification on rat calcium-permeable AMPA and kainate receptorsQ57985787
Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticityQ59065408
Block of native Ca(2+)-permeable AMPA receptors in rat brain by intracellular polyamines generates double rectificationQ71513383
SAP97 concentrates at the postsynaptic density in cerebral cortexQ73072468
A role for protein kinase C in a form of metaplasticity that regulates the induction of long-term potentiation at CA1 synapses of the adult rat hippocampusQ73167527
Regulation of A-kinase anchoring protein 79/150-cAMP-dependent protein kinase postsynaptic targeting by NMDA receptor activation of calcineurin and remodeling of dendritic actinQ28570353
A beta2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2Q28572706
PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticityQ28574179
Association of an A-kinase-anchoring protein signaling scaffold with cadherin adhesion molecules in neurons and epithelial cellsQ28576588
Postnatal synaptic potentiation: delivery of GluR4-containing AMPA receptors by spontaneous activityQ28582527
Calcium-stimulated adenylyl cyclase activity is critical for hippocampus-dependent long-term memory and late phase LTPQ28586321
Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memoryQ28588695
Receptor trafficking and synaptic plasticityQ29041960
Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sortingQ29615874
AMPA Receptor Trafficking at Excitatory SynapsesQ29617540
AKAP signalling complexes: focal points in space and timeQ29618533
Learning induces long-term potentiation in the hippocampusQ29619482
Synaptic plasticity and memory: an evaluation of the hypothesisQ29619840
Synaptic AMPA receptor exchange maintains bidirectional plasticityQ30440169
PDZ proteins interacting with C-terminal GluR2/3 are involved in a PKC-dependent regulation of AMPA receptors at hippocampal synapses.Q33932164
A developmental switch in the signaling cascades for LTP inductionQ33962983
Regulation of AMPA receptor lateral movementsQ34132003
Critical periods for experience-dependent synaptic scaling in visual cortexQ34134898
Phosphorylation of the alpha-amino-3-hydroxy-5-methylisoxazole4-propionic acid receptor GluR1 subunit by calcium/calmodulin-dependent kinase II.Q34450034
Recruitment of long-lasting and protein kinase A-dependent long-term potentiation in the CA1 region of hippocampus requires repeated tetanization.Q34504827
Forskolin-induced LTP in the CA1 hippocampal region is NMDA receptor dependent.Q34544318
Synaptic incorporation of AMPA receptors during LTP is controlled by a PKC phosphorylation site on GluR1.Q34548349
Increased phosphorylation of the neuronal L-type Ca(2+) channel Ca(v)1.2 during agingQ34794659
Regulation of {alpha}-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking through PKA phosphorylation of the Glu receptor 1 subunitQ35652545
Isolation and characterization of postsynaptic densities from various brain regions: enrichment of different types of postsynaptic densitiesQ36201722
A unified model of the presynaptic and postsynaptic changes during LTP at CA1 synapsesQ36619940
Distinct roles of the beta 1-class integrins at the developing and the mature hippocampal excitatory synapseQ37218724
Direct imaging of lateral movements of AMPA receptors inside synapsesQ39958761
Inward rectification of both AMPA and kainate subtype glutamate receptors generated by polyamine-mediated ion channel blockQ41316722
Expression of a kinase anchor protein 75 depletes type II cAMP-dependent protein kinases from the cytoplasm and sequesters the kinases in a particulate pool.Q41559868
Adenylyl cyclase activation modulates activity-dependent changes in synaptic strength and Ca2+/calmodulin-dependent kinase II autophosphorylation.Q41615359
Displacement of alpha-actinin from the NMDA receptor NR1 C0 domain By Ca2+/calmodulin promotes CaMKII bindingQ42129724
Disruption of the NMDA receptor-PSD-95 interaction in hippocampal neurons with no obvious physiological short-term effectQ42451089
Dopamine receptor stimulation modulates AMPA receptor synaptic insertion in prefrontal cortex neurons.Q42482481
Regulation of GluR1 by the A-kinase anchoring protein 79 (AKAP79) signaling complex shares properties with long-term depression.Q42519960
A high-efficiency protein transduction system demonstrating the role of PKA in long-lasting long-term potentiation.Q43697222
Postsynaptic application of a peptide inhibitor of cAMP-dependent protein kinase blocks expression of long-lasting synaptic potentiation in hippocampal neurons.Q44323429
Glutamate Receptor Subunit 2 Serine 880 Phosphorylation Modulates Synaptic Transmission and Mediates Plasticity in CA1 Pyramidal CellsQ44610940
Affinity purification of PSD-95-containing postsynaptic complexes.Q44658052
Modulation of dopamine mediated phosphorylation of AMPA receptors by PSD-95 and AKAP79/150.Q45086263
A critical period for long-term potentiation at thalamocortical synapsesQ46179242
P433issue23
P407language of work or nameEnglishQ1860
P304page(s)4879-4890
P577publication date2007-11-01
P1433published inThe EMBO JournalQ1278554
P1476titleAge-dependent requirement of AKAP150-anchored PKA and GluR2-lacking AMPA receptors in LTP.
P478volume26

Reverse relations

cites work (P2860)
Q34147548A calcineurin/AKAP complex is required for NMDA receptor–dependent long-term depression
Q35128184A kinase anchor protein 150 (AKAP150)-associated protein kinase A limits dendritic spine density.
Q34084438A presynaptic role for PKA in synaptic tagging and memory.
Q27319948A role for calcium-permeable AMPA receptors in synaptic plasticity and learning
Q26999034A role of TARPs in the expression and plasticity of calcium-permeable AMPARs: evidence from cerebellar neurons and glia
Q36159125A-kinase anchoring proteins as potential drug targets
Q37865993AKAP signaling complexes in regulation of excitatory synaptic plasticity
Q42281570AKAP-anchored PKA maintains neuronal L-type calcium channel activity and NFAT transcriptional signaling.
Q37362251AKAP-scaffolding proteins and regulation of cardiac physiology.
Q57796322AKAP150 Palmitoylation Regulates Synaptic Incorporation of Ca-Permeable AMPA Receptors to Control LTP
Q45517162AKAP150-anchored PKA activity is important for LTD during its induction phase.
Q36418127AKAP150-anchored calcineurin regulates synaptic plasticity by limiting synaptic incorporation of Ca2+-permeable AMPA receptors.
Q33825161AKAP79 interacts with multiple adenylyl cyclase (AC) isoforms and scaffolds AC5 and -6 to alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) receptors
Q34559462AKAP79/150 impacts intrinsic excitability of hippocampal neurons through phospho-regulation of A-type K+ channel trafficking
Q34233602AMPA receptor plasticity in the nucleus accumbens after repeated exposure to cocaine
Q52687549AMPA-Type Glutamate Receptor Conductance Changes and Plasticity: Still a Lot of Noise.
Q37048376Acquisition of contextual discrimination involves the appearance of a RAS-GRF1/p38 mitogen-activated protein (MAP) kinase-mediated signaling pathway that promotes long term potentiation (LTP)
Q43097994Activity-dependent transcriptional regulation of M-Type (Kv7) K(+) channels by AKAP79/150-mediated NFAT actions
Q36929153Adenylyl cyclase anchoring by a kinase anchor protein AKAP5 (AKAP79/150) is important for postsynaptic β-adrenergic signaling
Q37415827Adenylyl cyclase--A-kinase anchoring protein complexes: the next dimension in cAMP signaling
Q35793227Adolescent alcohol exposure: Are there separable vulnerable periods within adolescence?
Q37385656Age matters
Q35947448Aging, synaptic dysfunction, and insulin-like growth factor (IGF)-1
Q35958258An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A.
Q36586635An essential role for PICK1 in NMDA receptor-dependent bidirectional synaptic plasticity
Q28581205Assembly of a beta2-adrenergic receptor--GluR1 signalling complex for localized cAMP signalling
Q61979192Beyond Intracellular Signaling: The Ins and Outs of Second Messengers Microdomains
Q28565532Brain-derived neurotrophic factor activation of CaM-kinase kinase via transient receptor potential canonical channels induces the translation and synaptic incorporation of GluA1-containing calcium-permeable AMPA receptors
Q33405238Ca(2+) permeable AMPA receptor induced long-term potentiation requires PI3/MAP kinases but not Ca/CaM-dependent kinase II.
Q37986040Ca-permeable AMPA receptors in homeostatic synaptic plasticity
Q30157070Ca2+/calmodulin-dependent protein kinase II binds to and phosphorylates a specific SAP97 splice variant to disrupt association with AKAP79/150 and modulate alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptor (AMPAR) acti
Q28510123CaMKII binding to GluN2B is critical during memory consolidation
Q47340161CaMKII regulates the depalmitoylation and synaptic removal of the scaffold protein AKAP79/150 to mediate structural long-term depression
Q27002483Cell biology in neuroscience: the interplay between Hebbian and homeostatic synaptic plasticity
Q50026048Control of Homeostatic Synaptic Plasticity by AKAP-Anchored Kinase and Phosphatase Regulation of Ca2+-Permeable AMPA Receptors
Q36323396Coordination of Protein Phosphorylation and Dephosphorylation in Synaptic Plasticity
Q99206499Developmental onset of enduring long-term potentiation in mouse hippocampus
Q34411061Developmental regulation of protein interacting with C kinase 1 (PICK1) function in hippocampal synaptic plasticity and learning
Q37077042Developmental switch in requirement for PKA RIIbeta in NMDA-receptor-dependent synaptic plasticity at Schaffer collateral to CA1 pyramidal cell synapses
Q44239602Differentially expressed three non-coding alternate exons at 5' UTR of regulatory type I beta subunit gene of mouse
Q41969989Distinct subunit-specific α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking mechanisms in cultured cortical and hippocampal neurons in response to oxygen and glucose deprivation.
Q42371373Do Low Serum UCH-L1 and TDP-43 Levels Indicate Disturbed Ubiquitin-Proteosome System in Autism Spectrum Disorder?
Q38020166Drug-evoked plasticity: do addictive drugs reopen a critical period of postnatal synaptic development?
Q34975533GluA2-lacking, calcium-permeable AMPA receptors--inducers of plasticity?
Q36497093Gravin orchestrates protein kinase A and β2-adrenergic receptor signaling critical for synaptic plasticity and memory.
Q55287109Homeostatic synaptic scaling: molecular regulators of synaptic AMPA-type glutamate receptors.
Q38818317How Ca2+-permeable AMPA receptors, the kinase PKA, and the phosphatase PP2B are intertwined in synaptic LTP and LTD.
Q44344700Identification of a signaling cascade that maintains constitutive δ-opioid receptor incompetence in peripheral sensory neurons
Q37350705Incorporation of inwardly rectifying AMPA receptors at silent synapses during hippocampal long-term potentiation
Q33862019Increased insertion of glutamate receptor 2-lacking alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors at hippocampal synapses upon repeated morphine administration
Q38168193Leptin regulation of hippocampal synaptic function in health and disease.
Q43185201Leptin reverses long-term potentiation at hippocampal CA1 synapses
Q33825907Liberated PKA Catalytic Subunits Associate with the Membrane via Myristoylation to Preferentially Phosphorylate Membrane Substrates
Q37054831Long-term potentiation of synaptic transmission in the adult mouse insular cortex: multielectrode array recordings
Q42423084Long-term potentiation-dependent spine enlargement requires synaptic Ca2+-permeable AMPA receptors recruited by CaM-kinase I.
Q36858666Loss of AKAP150 perturbs distinct neuronal processes in mice
Q60046450Mechanisms of AMPA Receptor Endosomal Sorting
Q37783810Mechanisms of protein kinase A anchoring
Q38282299Minireview: Food for thought: regulation of synaptic function by metabolic hormones
Q41027183Morphine-induced synaptic plasticity in the VTA is reversed by HDAC inhibition.
Q33567678Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice
Q37022458NMDA Receptor-Dependent LTD Requires Transient Synaptic Incorporation of Ca²⁺-Permeable AMPARs Mediated by AKAP150-Anchored PKA and Calcineurin
Q48401502PICK1 mediates transient synaptic expression of GluA2-lacking AMPA receptors during glycine-induced AMPA receptor trafficking.
Q40753019PKCλ: a new player in LTP coming to the rescue of PKCζ's faltering role in LTP?
Q36009594Palmitoylation of A-kinase anchoring protein 79/150 regulates dendritic endosomal targeting and synaptic plasticity mechanisms.
Q33978048Perisynaptic GluR2-lacking AMPA receptors control the reversibility of synaptic and spines modifications
Q42000949Phosphorylation of Cav1.2 on S1928 uncouples the L-type Ca2+ channel from the β2 adrenergic receptor
Q37479508Phosphorylation of Ser1166 on GluN2B by PKA is critical to synaptic NMDA receptor function and Ca2+ signaling in spines
Q37643798Phosphorylation of Ser1928 mediates the enhanced activity of the L-type Ca2+ channel Cav1.2 by the β2-adrenergic receptor in neurons
Q91941961Phosphorylation-Dependent Regulation of Ca2+-Permeable AMPA Receptors During Hippocampal Synaptic Plasticity
Q39752364Postsynaptic clustering and activation of Pyk2 by PSD-95
Q57462438Postsynaptic localization and regulation of AMPA receptors and Cav1.2 by β2 adrenergic receptor/PKA and Ca/CaMKII signaling
Q47270899Potential for therapeutic targeting of AKAP signaling complexes in nervous system disorders
Q90604094Proteasomal-mediated degradation of AKAP150 accompanies AMPAR endocytosis during cLTD
Q36077719Protein Kinase C (PKC)ζ Pseudosubstrate Inhibitor Peptide Promiscuously Binds PKC Family Isoforms and Disrupts Conventional PKC Targeting and Translocation
Q37094339Protein kinase A anchoring via AKAP150 is essential for TRPV1 modulation by forskolin and prostaglandin E2 in mouse sensory neurons
Q43143735Recruitment of calcium-permeable AMPA receptors during synaptic potentiation is regulated by CaM-kinase I.
Q36408077Regulation of NMDA receptor Ca2+ signalling and synaptic plasticity
Q35083736Regulation of Neuronal Function by Ras-GRF Exchange Factors
Q42934637Regulation of glutamate receptor trafficking by leptin
Q28581832Regulation of postsynaptic structure and function by an A-kinase anchoring protein-membrane-associated guanylate kinase scaffolding complex
Q37855172Routes, destinations and delays: recent advances in AMPA receptor trafficking
Q36237719S-palmitoylation regulates AMPA receptors trafficking and function: a novel insight into synaptic regulation and therapeutics
Q37760035Signal integration through blending, bolstering and bifurcating of intracellular information
Q33665597Simvastatin enhances hippocampal long-term potentiation in C57BL/6 mice.
Q37446524Stabilization of Ca2+-permeable AMPA receptors at perisynaptic sites by GluR1-S845 phosphorylation
Q37889023Structural modulation of dendritic spines during synaptic plasticity
Q28581895Subcellular dynamics of type II PKA in neurons
Q41835572Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels
Q37469745Targeted deletion of AKAP7 in dentate granule cells impairs spatial discrimination.
Q34787777Targeting of protein phosphatases PP2A and PP2B to the C-terminus of the L-type calcium channel Ca v1.2.
Q92402721The Onset and Progression of Hippocampal Synaptic Plasticity Deficits in the Q175FDN Mouse Model of Huntington Disease
Q59813083The Role of Calcium-Permeable AMPARs in Long-Term Potentiation at Principal Neurons in the Rodent Hippocampus
Q58575627The Role of Polyamine-Dependent Facilitation of Calcium Permeable AMPARs in Short-Term Synaptic Enhancement
Q38154393The developmental stages of synaptic plasticity.
Q35882740The essential role of AMPA receptor GluR2 subunit RNA editing in the normal and diseased brain
Q46450835The genetics of PKMζ and memory maintenance.
Q34946082The palmitoyl acyltransferase DHHC2 regulates recycling endosome exocytosis and synaptic potentiation through palmitoylation of AKAP79/150
Q33846567Trafficking of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA) receptor subunit GluA2 from the endoplasmic reticulum is stimulated by a complex containing Ca2+/calmodulin-activated kinase II (CaMKII) and PICK1 protein and by rel
Q93148410Transient appearance of Ca2+ -permeable AMPA receptors is crucial for the production of repetitive LTP-induced synaptic enhancement (RISE) in cultured hippocampal slices
Q33678921Viagra for your synapses: Enhancement of hippocampal long-term potentiation by activation of beta-adrenergic receptors
Q59813452Visualization of Exo- and Endocytosis of AMPA Receptors During Hippocampal Synaptic Plasticity Around Postsynaptic-Like Membrane Formed on Glass Surface
Q30493570eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation.
Q90335850β2 Adrenergic Receptor Complexes with the L-Type Ca2+ Channel CaV1.2 and AMPA-Type Glutamate Receptors: Paradigms for Pharmacological Targeting of Protein Interactions
Q35994868β2-Adrenergic receptor supports prolonged theta tetanus-induced LTP

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