Protein kinase A anchoring via AKAP150 is essential for TRPV1 modulation by forskolin and prostaglandin E2 in mouse sensory neurons

scientific article published on May 2008

Protein kinase A anchoring via AKAP150 is essential for TRPV1 modulation by forskolin and prostaglandin E2 in mouse sensory neurons is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.0233-08.2008
P932PMC publication ID2641040
P698PubMed publication ID18463244
P5875ResearchGate publication ID5388871

P2093author name stringJohannes W Hell
Stefan Strack
Yuriy M Usachev
G Stanley McKnight
Blake Nichols
Katrin Schnizler
Leonid P Shutov
Michael J Van Kanegan
Michelle A Merrill
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TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonistsQ28263455
TRPV1: a therapeutic target for novel analgesic drugs?Q28265119
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The vanilloid receptor TRPV1 is tonically activated in vivo and involved in body temperature regulationQ28295455
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Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamideQ28345160
Impaired nociception and pain sensation in mice lacking the capsaicin receptorQ28511370
Prostaglandin receptor subtypes, EP3C and EP4, mediate the prostaglandin E2-induced cAMP production and sensitization of sensory neuronsQ28565840
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AKAP150 signaling complex promotes suppression of the M-current by muscarinic agonistsQ28574598
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The cloned capsaicin receptor integrates multiple pain-producing stimuliQ29547511
AKAP signalling complexes: focal points in space and timeQ29618533
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesiaQ29620385
Comparison of intracellular calcium signals evoked by heat and capsaicin in cultured rat dorsal root ganglion neurons and in a cell line expressing the rat vanilloid receptor, VR1.Q32065610
Reduced thermal sensitivity and Nav1.8 and TRPV1 channel expression in sensory neurons of aged miceQ33739335
The vanilloid receptor: a molecular gateway to the pain pathwayQ33941065
A kinase-anchoring protein 150 and calcineurin are involved in regulation of acid-sensing ion channels ASIC1a and ASIC2aQ34634258
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Structure and function of TRPV1.Q36170840
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Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1).Q36350876
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A-kinase anchoring proteins take shapeQ36463252
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Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sitesQ38326421
Glial cell line-derived neurotrophic factor family members sensitize nociceptors in vitro and produce thermal hyperalgesia in vivo.Q40242652
Increased sensitivity of desensitized TRPV1 by PMA occurs through PKCepsilon-mediated phosphorylation at S800.Q40299929
Regulation of Ca2+-dependent desensitization in the vanilloid receptor TRPV1 by calcineurin and cAMP-dependent protein kinase.Q40461994
Desensitization of Capsaicin-activated Currents in the Vanilloid Receptor TRPV1 Is Decreased by the Cyclic AMP-dependent Protein Kinase PathwayQ40631931
Bradykinin lowers the threshold temperature for heat activation of vanilloid receptor 1.Q40721410
Glial cell line-derived neurotrophic factor is a survival factor for isolectin B4-positive, but not vanilloid receptor 1-positive, neurons in the mouse.Q40730618
Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residuesQ40746070
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Coordination of three signaling enzymes by AKAP79, a mammalian scaffold proteinQ41216893
Enhancement of potency and efficacy of NADA by PKC-mediated phosphorylation of vanilloid receptorQ42457403
Prostaglandin E2 receptor EP4 contributes to inflammatory pain hypersensitivity.Q42501246
Regulation of GluR1 by the A-kinase anchoring protein 79 (AKAP79) signaling complex shares properties with long-term depression.Q42519960
Changes in cytosolic calcium in response to noxious heat and their relationship to vanilloid receptors in rat dorsal root ganglion neuronsQ43621068
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Peripheral group II metabotropic glutamate receptors (mGluR2/3) regulate prostaglandin E2-mediated sensitization of capsaicin responses and thermal nociception.Q44085153
cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylationQ44113663
Prostaglandin and protein kinase A-dependent modulation of vanilloid receptor function by metabotropic glutamate receptor 5: potential mechanism for thermal hyperalgesia.Q44115026
Molecular mechanism of convergent regulation of brain Na(+) channels by protein kinase C and protein kinase A anchored to AKAP-15.Q44163841
Versatile regulation of cytosolic Ca2+ by vanilloid receptor I in rat dorsal root ganglion neurons.Q44231108
Ca2+ transient evoked by chemical stimulation is enhanced by PGE2 in vagal sensory neurons: role of cAMP/PKA signaling pathwayQ44336931
Activation of protein kinase C reverses capsaicin-induced calcium-dependent desensitization of TRPV1 ion channelsQ44788457
TRPV1 function in mouse colon sensory neurons is enhanced by metabotropic 5-hydroxytryptamine receptor activation.Q45127969
AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic propertiesQ45199036
Selective blockade of the capsaicin receptor TRPV1 attenuates bone cancer pain.Q46402734
Role of transient receptor potential vanilloid 1 receptors in adjuvant-induced chronic arthritis: in vivo study using gene-deficient miceQ46438614
Epac mediates a cAMP-to-PKC signaling in inflammatory pain: an isolectin B4(+) neuron-specific mechanism.Q46471284
Diminished inflammation and nociceptive pain with preservation of neuropathic pain in mice with a targeted mutation of the type I regulatory subunit of cAMP-dependent protein kinaseQ46490168
The mechanosensitivity of mouse colon afferent fibers and their sensitization by inflammatory mediators require transient receptor potential vanilloid 1 and acid-sensing ion channel 3.Q46818690
TRPV1 recapitulates native capsaicin receptor in sensory neurons in association with Fas-associated factor 1.Q46970956
The cAMP transduction cascade mediates the prostaglandin E2 enhancement of the capsaicin-elicited current in rat sensory neurons: whole-cell and single-channel studies.Q47710518
Critical role of cAMP-dependent protein kinase anchoring to the L-type calcium channel Cav1.2 via A-kinase anchor protein 150 in neuronsQ48284563
AKAP15 anchors cAMP-dependent protein kinase to brain sodium channelsQ48390175
Involvement of transient receptor potential vanilloid 1 in the vascular and hyperalgesic components of joint inflammation.Q48748066
Vanilloid receptor 1 regulates multiple calcium compartments and contributes to Ca2+-induced Ca2+ release in sensory neurons.Q51037112
Peptides for disruption of PKA anchoring.Q52572282
Identification of a 15-kDa cAMP-dependent protein kinase-anchoring protein associated with skeletal muscle L-type calcium channels.Q53893788
Impaired nociception and inflammatory pain sensation in mice lacking the prokineticin receptor PKR1: focus on interaction between PKR1 and the capsaicin receptor TRPV1 in pain behavior.Q54595603
Emergence of Functional Sensory Subtypes as Defined by Transient Receptor Potential Channel ExpressionQ60695001
Prostaglandins facilitate peptide release from rat sensory neurons by activating the adenosine 3',5'-cyclic monophosphate transduction cascadeQ71924140
The role of calcium in capsaicin-induced desensitization in rat cultured dorsal root ganglion neuronsQ72104507
The role of calcium in the desensitization of capsaicin responses in rat dorsal root ganglion neuronsQ73302761
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectprostaglandin E2Q416554
P304page(s)4904-4917
P577publication date2008-05-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleProtein kinase A anchoring via AKAP150 is essential for TRPV1 modulation by forskolin and prostaglandin E2 in mouse sensory neurons
P478volume28

Reverse relations

cites work (P2860)
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