Galectin-3 Blockade Reduces Renal Fibrosis in Two Normotensive Experimental Models of Renal Damage

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Galectin-3 Blockade Reduces Renal Fibrosis in Two Normotensive Experimental Models of Renal Damage is …
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scholarly articleQ13442814

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P819ADS bibcode2016PLoSO..1166272M
P356DOI10.1371/JOURNAL.PONE.0166272
P932PMC publication ID5102450
P698PubMed publication ID27829066

P50authorVictoria CachofeiroQ42731331
Ernesto Martinez-MartinezQ42364398
P2093author name stringPatrick Rossignol
Jaime Ibarrola
Laurent Calvier
Natalia Lopez-Andres
Celine Leroy
Amaya Fernandez-Celis
P2860cites workEpithin, a target of transforming growth factor-beta signaling, mediates epithelial-mesenchymal transitionQ43096173
Accelerated diabetic glomerulopathy in galectin-3/AGE receptor 3 knockout mice.Q43786750
Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysisQ44579295
A Role for galectin-3 in renal tissue damage triggered by ischemia and reperfusion injuryQ46461255
Chronic kidney disease as a global public health problem: approaches and initiatives - a position statement from Kidney Disease Improving Global OutcomesQ80477531
Mechanisms of tubulointerstitial fibrosisQ85074102
Reversibility of chronic kidney disease and outcomes following aortic valve replacement†Q85607054
Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3Q24624887
Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosisQ24649584
The Role of Galectin-3 in the KidneysQ26752754
Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis modelQ28142724
Up-regulation of galectin-3 in acute renal failure of the ratQ28344724
Regression of fibrosis and reversal of cirrhosis in rats by galectin inhibitors in thioacetamide-induced liver diseaseQ28534290
Risk of acute kidney injury in patients with severe aortic valve stenosis undergoing transcatheter valve replacementQ33383245
Modified citrus pectin reduces galectin-3 expression and disease severity in experimental acute kidney injuryQ33873592
The role of tubulointerstitial injury in chronic renal failure.Q33886665
Galectin-3 preserves renal tubules and modulates extracellular matrix remodeling in progressive fibrosisQ34501897
Usefulness of plasma galectin-3 levels in systolic heart failure to predict renal insufficiency and survival.Q35109460
Risk factors for progressive chronic kidney diseaseQ35159360
New insights into epithelial-mesenchymal transition in kidney fibrosisQ36010095
Renal fibroblasts and myofibroblasts in chronic kidney diseaseQ36621203
How does proteinuria cause progressive renal damage?Q36621209
Elevated galectin-3 precedes the development of CKDQ37119904
Inhibitory effect of modified citrus pectin on liver metastases in a mouse colon cancer modelQ37423079
Prediction, progression, and outcomes of chronic kidney disease in older adultsQ37496352
Epithelial-mesenchymal transition in renal fibrosis - evidence for and against.Q37873557
Galectin-3 inhibition prevents adipose tissue remodelling in obesity.Q38382993
Galectin-3 blockade inhibits cardiac inflammation and fibrosis in experimental hyperaldosteronism and hypertensionQ38387964
Galectin-3 Participates in Cardiovascular Remodeling Associated With Obesity.Q40560953
Pharmacological inhibition of galectin-3 protects against hypertensive nephropathyQ41695164
The impact of galectin-3 inhibition on aldosterone-induced cardiac and renal injuries.Q41744993
Diet-induced obesity and kidney disease - In search of a susceptible mouse modelQ42062261
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectrenal fibrosisQ18553516
P304page(s)e0166272
P577publication date2016-11-09
P1433published inPLOS OneQ564954
P1476titleGalectin-3 Blockade Reduces Renal Fibrosis in Two Normotensive Experimental Models of Renal Damage
P478volume11

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cites work (P2860)
Q33754895Clinical Correlates and Prognostic Value of Plasma Galectin-3 Levels in Degenerative Aortic Stenosis: A Single-Center Prospective Study of Patients Referred for Invasive Treatment
Q90169765Galectin 3 protects from cisplatin-induced acute kidney injury by promoting TLR-2-dependent activation of IDO1/Kynurenine pathway in renal DCs
Q89429779Galectin-1 is a new fibrosis protein in type 1 and type 2 diabetes
Q55040652Hypoxia-inducible factor-1α regulates epithelial-to-mesenchymal transition in paraquat-induced pulmonary fibrosis by activating lysyl oxidase.
Q60050018IGFBP2 is a potential biomarker in acute kidney injury (AKI) and resveratrol-loaded nanoparticles prevent AKI
Q47649685Inhibition of galectin-3 ameliorates the consequences of cardiac lipotoxicity in a rat model of diet-induced obesity.
Q64923813Interaction between galectin-3 and cystinosin uncovers a pathogenic role of inflammation in kidney involvement of cystinosis.
Q91877907Letter to the Editor: Not all modified citrus pectins are the same: size does matter
Q40060474Plasma galectin-3 levels are associated with the risk of incident chronic kidney disease
Q47127873Synergistic Antioxidant and Anti-Inflammatory Effects between Modified Citrus Pectin and Honokiol

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