| scholarly article | Q13442814 |
| P2093 | author name string | Jeffrey L Barnes | |
| Balakuntalam S Kasinath | |||
| Goutam Ghosh Choudhury | |||
| Kavithalakshmi Sataranatarajan | |||
| Denis Feliers | |||
| Meenalakshmi M Mariappan | |||
| Myung Ja Lee | |||
| P2860 | cites work | Signalling to translation: how signal transduction pathways control the protein synthetic machinery | Q36765810 |
| Akt serine threonine kinase regulates platelet-derived growth factor-induced DNA synthesis in glomerular mesangial cells: regulation of c-fos AND p27(kip1) gene expression | Q43686297 | ||
| Activation of renal signaling pathways in db/db mice with type 2 diabetes | Q43688328 | ||
| Rapamycin attenuates load-induced cardiac hypertrophy in mice | Q44385669 | ||
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| Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease | Q45162599 | ||
| Role of mammalian target of rapamycin signaling in compensatory renal hypertrophy | Q46402341 | ||
| p27(Kip1) Knockout mice are protected from diabetic nephropathy: evidence for p27(Kip1) haplotype insufficiency | Q46704832 | ||
| Kidney involvement in a nongenetic rat model of type 2 diabetes | Q46826517 | ||
| Inhibition of mTOR signaling with rapamycin attenuates renal hypertrophy in the early diabetic mice | Q46858582 | ||
| Mammalian Target of Rapamycin Pathway Blockade Slows Progression of Diabetic Kidney Disease in Rats | Q59734510 | ||
| A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy | Q64018940 | ||
| Regulation of renal laminin in mice with type II diabetes | Q78223170 | ||
| High glucose, high insulin, and their combination rapidly induce laminin-beta1 synthesis by regulation of mRNA translation in renal epithelial cells | Q79678248 | ||
| Rapamycin attenuates unilateral ureteral obstruction-induced renal fibrosis | Q83864077 | ||
| Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action | Q24302566 | ||
| Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase. | Q24535599 | ||
| The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform | Q24678511 | ||
| TOR signaling in growth and metabolism | Q27860757 | ||
| GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR | Q28115142 | ||
| TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling | Q28131740 | ||
| Mutation of Tyr307 and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2 | Q28141657 | ||
| The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif | Q28211968 | ||
| Regulation of elongation factor-2 by multisite phosphorylation | Q28263254 | ||
| Upstream and downstream of mTOR | Q28277365 | ||
| mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events | Q28281590 | ||
| Identification of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2 | Q28303188 | ||
| Angiotensin II inhibits insulin-stimulated phosphorylation of eukaryotic initiation factor 4E-binding protein-1 in proximal tubular epithelial cells | Q28363300 | ||
| Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway | Q28646919 | ||
| A PCR primer bank for quantitative gene expression analysis | Q33447710 | ||
| Extracellular matrix metabolism in diabetic nephropathy | Q34192033 | ||
| Diabetic kidney disease in thedb/dbmouse | Q34195384 | ||
| Prevention of diabetic nephropathy in db/db mice with glycated albumin antagonists. A novel treatment strategy | Q34218935 | ||
| Origin of interstitial fibroblasts in an accelerated model of angiotensin II-induced renal fibrosis | Q35085426 | ||
| Not just for housekeeping: protein initiation and elongation factors in cell growth and tumorigenesis | Q35191607 | ||
| Characterization of a renal tubular epithelial cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis | Q36219361 | ||
| mRNA translation: unexplored territory in renal science | Q36588736 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | sirolimus | Q32089 |
| diabetic nephropathy | Q1129105 | ||
| P304 | page(s) | 1733-1742 | |
| P577 | publication date | 2007-11-08 | |
| P1433 | published in | The American Journal of Pathology | Q4744259 |
| P1476 | title | Regulation of elongation phase of mRNA translation in diabetic nephropathy: amelioration by rapamycin | |
| P478 | volume | 171 |
| Q34737936 | Activation of glycogen synthase kinase 3β ameliorates diabetes-induced kidney injury |
| Q36514846 | Activation of the Renal PI3K/Akt/mTOR Signaling Pathway in a DOCA-Salt Model of Hypertension |
| Q37851872 | Aging and cancer: can mTOR inhibitors kill two birds with one drug? |
| Q59799713 | Akt2 causes TGFβ-induced deptor downregulation facilitating mTOR to drive podocyte hypertrophy and matrix protein expression |
| Q42793410 | Alpha‐lipoic acid does not alter stress protein response to acute exercise in diabetic brain |
| Q37949588 | Autophagy as a therapeutic target in diabetic nephropathy |
| Q40124684 | Autophagy downregulation contributes to insulin resistance mediated injury in insulin receptor knockout podocytes in vitro. |
| Q46312225 | Autophagy in diabetic kidney disease: regulation, pathological role and therapeutic potential |
| Q34445143 | Autophagy in diabetic nephropathy |
| Q35830508 | Comparative Genome of GK and Wistar Rats Reveals Genetic Basis of Type 2 Diabetes |
| Q36194753 | Emerging role of autophagy in kidney function, diseases and aging |
| Q26799567 | Endoplasmic Reticulum Stress in the Diabetic Kidney, the Good, the Bad and the Ugly |
| Q84712603 | Everolimus vs. rapamycin for treating diabetic nephropathy in diabetic mouse model |
| Q92577217 | Fasting and rapamycin: diabetes versus benevolent glucose intolerance |
| Q39950939 | Glycogen synthase kinase 3beta is a novel regulator of high glucose- and high insulin-induced extracellular matrix protein synthesis in renal proximal tubular epithelial cells |
| Q34131013 | HIV-1 promotes renal tubular epithelial cell protein synthesis: role of mTOR pathway. |
| Q34033416 | HIV-associated nephropathy: role of mammalian target of rapamycin pathway. |
| Q35625038 | High glucose enhances microRNA-26a to activate mTORC1 for mesangial cell hypertrophy and matrix protein expression |
| Q34552665 | High glucose forces a positive feedback loop connecting Akt kinase and FoxO1 transcription factor to activate mTORC1 kinase for mesangial cell hypertrophy and matrix protein expression |
| Q42073523 | High glucose upregulation of early-onset Parkinson's disease protein DJ-1 integrates the PRAS40/TORC1 axis to mesangial cell hypertrophy |
| Q92189174 | Huang-Lian Jie-Du decoction: a review on phytochemical, pharmacological and pharmacokinetic investigations |
| Q38785627 | Hydrogen Sulfide in Renal Physiology and Disease |
| Q54979927 | Hydrogen sulfide ameliorates aging-associated changes in the kidney. |
| Q35763027 | Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells |
| Q36775718 | Hydrophobic motif site-phosphorylated protein kinase CβII between mTORC2 and Akt regulates high glucose-induced mesangial cell hypertrophy |
| Q35895695 | IGF-I increases the expression of fibronectin by Nox4-dependent Akt phosphorylation in renal tubular epithelial cells |
| Q36891626 | Insights into the Mechanisms Involved in the Expression and Regulation of Extracellular Matrix Proteins in Diabetic Nephropathy |
| Q38162106 | Interventions against nutrient-sensing pathways represent an emerging new therapeutic approach for diabetic nephropathy |
| Q91717305 | Klotho protein supplementation reduces blood pressure and renal hypertrophy in db/db mice, a model of type 2 diabetes |
| Q35143026 | Knockout of toll-like receptor-2 attenuates both the proinflammatory state of diabetes and incipient diabetic nephropathy |
| Q39247355 | Mammalian target of rapamycin (mTOR) as a potential therapeutic target in various diseases |
| Q39104277 | Mammalian target of rapamycin (mTOR): a central regulator of male fertility? |
| Q38002007 | Mammalian target of rapamycin and the kidney. II. Pathophysiology and therapeutic implications |
| Q37031034 | Mammalian target of rapamycin regulates Nox4-mediated podocyte depletion in diabetic renal injury. |
| Q57468895 | Marmoset as a model to study kidney changes associated with aging |
| Q41813557 | Mechanism of VEGF expression by high glucose in proximal tubule epithelial cells |
| Q35110986 | MicroRNA-21 orchestrates high glucose-induced signals to TOR complex 1, resulting in renal cell pathology in diabetes |
| Q49761677 | Molecular events in matrix protein metabolism in the aging kidney |
| Q37226576 | Novel mechanisms of protein synthesis in diabetic nephropathy--role of mRNA translation |
| Q35612372 | Nutrient sensing, autophagy, and diabetic nephropathy |
| Q47911791 | PDGF receptor-β uses Akt/mTORC1 signaling node to promote high glucose-induced renal proximal tubular cell collagen I (α2) expression |
| Q42713697 | PRAS40 acts as a nodal regulator of high glucose-induced TORC1 activation in glomerular mesangial cell hypertrophy |
| Q37297659 | Pirfenidone is renoprotective in diabetic kidney disease |
| Q35624799 | Podocyte hypertrophy precedes apoptosis under experimental diabetic conditions |
| Q37760379 | Prospects for mTOR inhibitor use in patients with polycystic kidney disease and hamartomatous diseases |
| Q37000451 | Rapamycin Increases Mortality in db/db Mice, a Mouse Model of Type 2 Diabetes |
| Q90510568 | Rapamycin for longevity: opinion article |
| Q37950771 | Rapamycin passes the torch: a new generation of mTOR inhibitors |
| Q36159499 | Rapamycin selectively alters serum chemistry in diabetic mice |
| Q47828965 | Reciprocal regulation of miR-214 and PTEN by high glucose regulates renal glomerular mesangial and proximal tubular epithelial cell hypertrophy and matrix expansion. |
| Q33655715 | Reductions in laminin beta2 mRNA translation are responsible for impaired IGFBP-5-mediated mesangial cell migration in the presence of high glucose |
| Q34609025 | Regulation of mRNA translation in renal physiology and disease |
| Q46473326 | Renal activity of Akt kinase in obese Zucker rats |
| Q39797671 | Resveratrol ameliorates high glucose-induced protein synthesis in glomerular epithelial cells |
| Q54640476 | Rho kinase inhibition protects kidneys from diabetic nephropathy without reducing blood pressure. |
| Q28571792 | Ribosomal biogenesis induction by high glucose requires activation of upstream binding factor in kidney glomerular epithelial cells |
| Q26828026 | Role of nutrient-sensing signals in the pathogenesis of diabetic nephropathy |
| Q35791976 | Signaling mechanisms in the regulation of renal matrix metabolism in diabetes |
| Q41974987 | TGFβ enforces activation of eukaryotic elongation factor‐2 (eEF2) via inactivation of eEF2 kinase by p90 ribosomal S6 kinase (p90Rsk) to induce mesangial cell hypertrophy |
| Q35354812 | TGFβ-induced deptor suppression recruits mTORC1 and not mTORC2 to enhance collagen I (α2) gene expression |
| Q28975741 | TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion |
| Q40227243 | The association of LAMB1 polymorphism and expression changes with the risk of coal workers' pneumoconiosis |
| Q92332250 | The mystery of the ketogenic diet: benevolent pseudo-diabetes |
| Q36347614 | Timosaponin B-II ameliorates diabetic nephropathy via TXNIP, mTOR, and NF-κB signaling pathways in alloxan-induced mice |
| Q37317428 | Tissue-specific remodeling of the mitochondrial proteome in type 1 diabetic akita mice. |
| Q36685205 | Transforming growth factor β integrates Smad 3 to mechanistic target of rapamycin complexes to arrest deptor abundance for glomerular mesangial cell hypertrophy |
| Q37810461 | mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression |
| Q41912848 | mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice |
| Q49353844 | microRNA-181a downregulates deptor for TGFβ-induced glomerular mesangial cell hypertrophy and matrix protein expression |
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