The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis

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The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.AJPATH.2012.05.013
P932PMC publication ID3432424
P698PubMed publication ID22901752
P5875ResearchGate publication ID230696894

P50authorChing-Cheng ChenQ42771371
Adrian M PiliponskyQ58890910
Asha LahiriQ60327389
Mindy TsaiQ78953219
Stephen J. GalliQ87756591
Piper M TreutingQ89685400
Gunnar PejlerQ90307224
Magnus AbrinkQ112230772
Eon J RiosQ114407156
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Distinct roles for lymphotoxin-alpha and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissueQ28586439
Cooperation between mast cell carboxypeptidase A and the chymase mouse mast cell protease 4 in the formation and degradation of angiotensin IIQ28592232
The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnoverQ28592458
The epidemiology of sepsis in the United States from 1979 through 2000Q29547760
The immunopathogenesis of sepsisQ29622909
Animal models of sepsis and sepsis-induced kidney injuryQ30490536
The extended cleavage specificity of the rodent beta-chymases rMCP-1 and mMCP-4 reveal major functional similarities to the human mast cell chymaseQ33293307
Mast cell-derived TNF can exacerbate mortality during severe bacterial infections in C57BL/6-KitW-sh/W-sh miceQ33597224
Dexamethasone and FK506 inhibit expression of distinct subsets of chemokines in human mast cellsQ33669494
Biological implications of preformed mast cell mediatorsQ33744155
Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsisQ33866102
Mouse mast cell protease-4 deteriorates renal function by contributing to inflammation and fibrosis in immune complex-mediated glomerulonephritisQ34306835
Mast cells promote homeostasis by limiting endothelin-1-induced toxicity.Q34367607
Mast cells can enhance resistance to snake and honeybee venomsQ34551900
Mast cell tryptases and chymases in inflammation and host defenseQ34627778
Strain-specific and tissue-specific expression of mouse mast cell secretory granule proteases.Q34906152
The enigma of sepsisQ35202458
Involvement of chymase-mediated angiotensin II generation in blood pressure regulationQ35233098
Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in miceQ35370039
New treatment strategies for severe sepsis and septic shockQ35542879
The pathogenesis of septic acute renal failureQ35593264
Acute renal failure and sepsisQ35833149
The "cytokine profile": a code for sepsisQ36032414
Molecular mechanism of mast cell mediated innate defense against endothelin and snake venom sarafotoxinQ36229090
Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosaQ36350812
In search of partners: linking extracellular proteases to substratesQ36735417
Mast cells in the promotion and limitation of chronic inflammation.Q36819950
Acute tubular necrosis is a syndrome of physiologic and pathologic dissociationQ37072228
Critical role of mast cell chymase in mouse abdominal aortic aneurysm formationQ37375537
Modulation of the renin-angiotensin-aldosterone system in sepsis: a new therapeutic approach?Q37650169
Mast cell proteases: multifaceted regulators of inflammatory diseaseQ37710252
IgE and mast cells in allergic diseaseQ38007829
Mast cell dipeptidyl peptidase I mediates survival from sepsisQ40553691
Tumor necrosis factor and endotoxin induce similar metabolic responses in human beingsQ40784780
W-sash affects positive and negative elements controlling c-kit expression: ectopic c-kit expression at sites of kit-ligand expression affects melanogenesisQ41075850
Role of tumor necrosis factor-alpha in lipopolysaccharide-induced pathologic alterations.Q42173056
Mast cell IL-6 improves survival from Klebsiella pneumonia and sepsis by enhancing neutrophil killingQ42193685
Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammationQ43258635
Role of C5a in multiorgan failure during sepsisQ43516359
Cytokine production by skin-derived mast cells: endogenous proteases are responsible for degradation of cytokinesQ44912677
The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infectionsQ45134515
Mast cell chymase contributes to the antibody response and the severity of autoimmune arthritisQ46245129
Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: protective and deleterious effects.Q53873432
Mast cells as a source of both preformed and immunologically inducible TNF-alpha/cachectin.Q54319446
IL-15 constrains mast cell-dependent antibacterial defenses by suppressing chymase activities.Q54437625
Monoclonal dinitrophenyl-specific murine IgE antibody: preparation, isolation, and characterizationQ61140921
Normal neutrophil function in cathepsin G-deficient miceQ73254135
Genetic background determines susceptibility during murine septic peritonitisQ77491588
Peritoneal cell-derived mast cells: an in vitro model of mature serosal-type mouse mast cellsQ80257401
Cutting edge: genetic variation influences Fc epsilonRI-induced mast cell activation and allergic responsesQ80582119
Endotoxemic acute renal failure is attenuated in caspase-1-deficient miceQ81256287
Harmful and protective roles of neutrophils in sepsisQ81909493
Cecal ligation and punctureQ82066536
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectmast cellQ191989
sepsisQ183134
P304page(s)875-886
P577publication date2012-09-01
P1433published inThe American Journal of PathologyQ4744259
P1476titleThe chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis
P478volume181

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