Potential effector and immunoregulatory functions of mast cells in mucosal immunity

scientific article published on 11 February 2015

Potential effector and immunoregulatory functions of mast cells in mucosal immunity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1042884724
P356DOI10.1038/MI.2014.131
P932PMC publication ID4739802
P698PubMed publication ID25669149
P5875ResearchGate publication ID272192077

P50authorStephen J. GalliQ87756591
P2093author name stringK Mukai
L L Reber
R Sibilano
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Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene familiesQ28512833
Abnormal mast cells in mice deficient in a heparin-synthesizing enzymeQ28586968
Heparin is essential for the storage of specific granule proteases in mast cellsQ28589787
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Mast cells/basophils in the peripheral blood of allergic individuals who are HIV-1 susceptible due to their surface expression of CD4 and the chemokine receptors CCR3, CCR5, and CXCR4.Q39177814
The aryl hydrocarbon receptor modulates acute and late mast cell responsesQ39339361
Histamine release from rat mast cells induced by Sendai virusQ39468697
Immune inflammatory responses to parasites: the role of basophils, mast cells and vasoactive aminesQ39469886
Signaling through Toll-like receptors triggers HIV-1 replication in latently infected mast cellsQ39499091
Adenosine potentiates human lung mast cell tissue plasminogen activator activityQ39621124
A critical role for mast cells and mast cell-derived IL-6 in TLR2-mediated inhibition of tumor growth.Q39637223
Differential responses of mast cell Toll-like receptors 2 and 4 in allergy and innate immunityQ39737899
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c-Kit immunophenotyping and metalloproteinase expression profiles of mast cells in interstitial lung diseasesQ40423991
Mast cell dipeptidyl peptidase I mediates survival from sepsisQ40553691
Contribution of mast cells to bacterial clearance and their proliferation during experimental cystitis induced by type 1 fimbriated E. coliQ40578879
Pseudomonas aeruginosa activates human mast cells to induce neutrophil transendothelial migration via mast cell-derived IL-1 alpha and betaQ40698972
Development of mast cells from grafted bone marrow cells in irradiated miceQ40802421
Immunity to helminths: is too much IgE parasite--rather than host-protective?Q40876214
Interleukin-33 amplifies IgE synthesis and triggers mast cell degranulation via interleukin-4 in naïve mice.Q40917393
The presence of novel amino acids in the cytoplasmic domain of stem cell factor results in hematopoietic defects in Steel(17H) miceQ40930521
Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship toQ41166399
Allergic host defencesQ41190858
Ultrastructural localization of heparin to human mast cells of the MCTC and MCT types by labeling with antithrombin III-gold.Q41516487
Ultrastructure of pulmonary mast cells in patients with fibrotic lung disordersQ41640529
IL-4 regulates c-kit proto-oncogene product expression in human mast and myeloid progenitor cellsQ41652897
Defective angiogenesis in the inflammatory granulation tissue in histidine decarboxylase-deficient mice but not in mast cell-deficient miceQ41809382
IL-18 with IL-2 protects against Strongyloides venezuelensis infection by activating mucosal mast cell-dependent type 2 innate immunityQ41815590
Ethanol-induced acute gastric injury in mast cell-deficient and congenic normal mice. Evidence that mast cells can augment the area of damageQ41851895
Thrombin functions as an inflammatory mediator through activation of its receptorQ41879963
Promotion of mouse fibroblast collagen gene expression by mast cells stimulated via the Fc epsilon RI. Role for mast cell-derived transforming growth factor beta and tumor necrosis factor alphaQ42029931
Induction of a selective and persistent extravasation of neutrophils into the peritoneal cavity by tryptase mouse mast cell protease 6.Q42061197
Delayed expulsion of the nematode Trichinella spiralis in mice lacking the mucosal mast cell-specific granule chymase, mouse mast cell protease-1.Q42118586
Mast cell IL-6 improves survival from Klebsiella pneumonia and sepsis by enhancing neutrophil killingQ42193685
Influence of mast cells on dengue protective immunity and immune pathologyQ35075102
Mast cell mediator responses and their suppression by pathogenic and commensal microorganismsQ35077675
Foxp3⁺ regulatory T cells delay expulsion of intestinal nematodes by suppression of IL-9-driven mast cell activation in BALB/c but not in C57BL/6 miceQ35091229
IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?Q35129625
Identification of an IFN-γ/mast cell axis in a mouse model of chronic asthmaQ35142807
Mast cells disrupt epithelial barrier function during enteric nematode infectionQ35146757
Mast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungsQ35157254
Protease phenotype of constitutive connective tissue and of induced mucosal mast cells in mice is regulated by the tissueQ35180574
Mast cell secretory granules: armed for battleQ35182662
Interferon-γ regulates growth and controls Fcγ receptor expression and activation in human intestinal mast cellsQ35201395
Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in miceQ35370039
Comparison of airway immunopathology of eosinophilic bronchitis and asthmaQ35535986
PTEN deficiency in mast cells causes a mastocytosis-like proliferative disease that heightens allergic responses and vascular permeabilityQ35553313
Stem cell factor: a hemopoietic cytokine with important targets in asthma.Q35560483
Two types of human mast cells that have distinct neutral protease compositionsQ35611922
Skin mast cells protect mice against vaccinia virus by triggering mast cell receptor S1PR2 and releasing antimicrobial peptidesQ35629472
Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl miceQ35631334
Mast cell-orchestrated immunity to pathogensQ35747350
Plasticity in mast cell responses during bacterial infectionsQ35767129
Viral bronchiolitis during early life induces increased numbers of bronchiolar mast cells and airway hyperresponsivenessQ35811684
Human tissue mast cells are an inducible reservoir of persistent HIV infectionQ35839856
Genetically mast-cell-deficient W/Wv and Sl/Sld mice. Their value for the analysis of the roles of mast cells in biologic responses in vivoQ35855942
Intracellular bacterial communities of uropathogenic Escherichia coli in urinary tract pathogenesisQ35874516
IL-4 and TGF-beta 1 counterbalance one another while regulating mast cell homeostasisQ35919517
Mast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokinesQ35921836
Stem cell factor programs the mast cell activation phenotypeQ35981165
Mast cells and basophils: friends as well as foes in bronchial asthma?Q35998285
Mast cells in the development of adaptive immune responsesQ36015885
Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challengeQ36023872
Mast cells as "tunable" effector and immunoregulatory cells: recent advances.Q36072458
Gastrointestinal food allergy: new insights into pathophysiology and clinical perspectivesQ36095885
Intra-epithelial mast cells in human airway epithelium: evidence for smoking-induced changes in their frequencyQ36120424
Commensal bacteria lipoteichoic acid increases skin mast cell antimicrobial activity against vaccinia virusesQ36139858
Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophilsQ36141195
Mast cell-derived TNF contributes to airway hyperreactivity, inflammation, and TH2 cytokine production in an asthma model in mice.Q51975504
Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma.Q52008756
Novel B cell population producing functional IgG in the absence of membrane IgM expression.Q52009310
Cre-mediated cell ablation contests mast cell contribution in models of antibody- and T cell-mediated autoimmunity.Q53204432
Clinical food hypersensitivity: the relevance of duodenal immunoglobulin E-positive cells.Q53944641
Mast cells, eosinophils and antibody-mediated cellular cytotoxicity are not critical in resistance to Trichuris muris.Q54102399
Comparison of intestinal mast cell and basophil histamine release in children with food allergic reactions.Q54104273
Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.Q54153238
Defective mucosal immunity and normal systemic immunity of Mongolian gerbils, Meriones unguiculatus, to reinfection with Strongyloides venezuelensis.Q54230673
Infection of Nippostrongylus brasiliensis induces development of mucosal-type but not connective tissue-type mast cells in genetically mast cell-deficient Ws/Ws ratsQ54240288
Mast cells as a source of both preformed and immunologically inducible TNF-alpha/cachectin.Q54319446
IL-12 and IL-10 production are differentially regulated by phosphatidylinositol 3-kinase in mast cells.Q54342513
IL-27/IFN-γ induce MyD88-dependent steroid-resistant airway hyperresponsiveness by inhibiting glucocorticoid signaling in macrophages.Q54412654
IL-15 constrains mast cell-dependent antibacterial defenses by suppressing chymase activities.Q54437625
Increased IL-33 expression by epithelial cells in bronchial asthma.Q54441538
New role for mast cells as IL-17-expressing effector cells in established RA.Q54494079
Further fatalities caused by anaphylactic reactions to food, 2001-2006.Q55043255
Evidence for Non-Allergic Mast Cell Activation in Pollen-Associated InflammationQ56984189
TLR3-induced activation of mast cells modulates CD8+ T-cell recruitmentQ56984288
Early macrophage influx to sites of cutaneous granuloma formation is dependent on MIP-1alpha /beta released from neutrophils recruited by mast cell-derived TNFalphaQ56984310
IL-33 can promote survival, adhesion and cytokine production in human mast cellsQ57273112
Histamine releasing and anti-inflammatory activities of MCD-peptide and its modified formsQ57775431
Mast cell numbers in airway smooth muscle and PC20AMP in asthma and COPDQ57891979
Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthmaQ58428764
Stem cell factor is localized in, released from, and cleaved by human mast cellsQ58911146
Absence of intestinal mast cell response in congenitally athymic mice during Trichinella spiralis infectionQ59065396
Critical protective role of mast cells in a model of acute septic peritonitisQ59072203
Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-αQ59092114
Mast Cells Are Key Promoters of Contact Allergy that Mediate the Adjuvant Effects of HaptensQ59404503
Human mast cells express stem cell factorQ59685227
H4 histamine receptor mediates optimal migration of mast cell precursors to CXCL12Q61895183
Mast Cells as Sensors of Cell Injury through IL-33 RecognitionQ63257866
Production of TNF-alpha by murine bone marrow derived mast cells activated by the bacterial fimbrial protein, FimHQ64449839
Identification of a cathepsin G-like proteinase in the MCTC type of human mast cell.Q64947865
Histamine Release from Cord Blood BasophilsQ67695832
T-cell-dependent accumulation of eosinophils in the lung and its inhibition by monoclonal anti-interleukin-5Q68039485
Deficiency of the tryptase-positive, chymase-negative mast cell type in gastrointestinal mucosa of patients with defective T lymphocyte functionQ68155580
Allergy in long-term hemodialysis. II. Allergic and atopic patterns of a population of patients undergoing long-term hemodialysisQ68276096
Multiple bidirectional alterations of phenotype and changes in proliferative potential during the in vitro and in vivo passage of clonal mast cell populations derived from mouse peritoneal mast cellsQ68501985
Experimental pulmonary eosinophilia in mice by Ascaris suum extractQ68785323
Mast cell and neutrophil interactions: a role for superoxide anion and histamineQ68936180
The immune response to nematode parasites: modulation of mast cell numbers and function during Strongyloides stercoralis infections in nonhuman primatesQ69136460
The mast cell binding site on human immunoglobulin EQ70375074
Expulsion of Trichinella spiralis from the intestine of W/Wv mice reconstituted with haematopoietic and lymphopoietic cells and origin of mucosal mast cellsQ70388955
A new allele sash (Wsh) at the W-locus and a spontaneous recessive lethal in miceQ70451803
Double-blind controlled trial of effect of housedust-mite allergen avoidance on atopic dermatitisQ70811486
Physical mapping of the Tec and Gabrb1 loci reveals that the Wsh mutation on mouse chromosome 5 is associated with an inversionQ70972744
The number and affinity of IgE receptors on dispersed human lung mast cellsQ71042943
Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research ProgramQ30428466
Mast cells augment adaptive immunity by orchestrating dendritic cell trafficking through infected tissuesQ30434434
Perivascular mast cells dynamically probe cutaneous blood vessels to capture immunoglobulin E.Q30536317
Evaluation of the substrate specificity of human mast cell tryptase beta I and demonstration of its importance in bacterial infections of the lungQ30666014
Fatalities due to anaphylactic reactions to foodsQ31812490
Expansion of the mast cell chymase locus over the past 200 million years of mammalian evolutionQ33248306
The extended cleavage specificity of the rodent beta-chymases rMCP-1 and mMCP-4 reveal major functional similarities to the human mast cell chymaseQ33293307
Increased expression of IL-33 in severe asthma: evidence of expression by airway smooth muscle cellsQ33508406
Cell-cell cooperation at the T helper cell/mast cell immunological synapseQ33508777
Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin-basophil axisQ33554604
Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanismQ33564179
Mast cell-derived TNF can exacerbate mortality during severe bacterial infections in C57BL/6-KitW-sh/W-sh miceQ33597224
Regulation of human mast cell and basophil function by anaphylatoxins C3a and C5a.Q33625259
Mast cells are required for experimental oral allergen-induced diarrheaQ33630242
Immunologic basis of antigen-induced airway hyperresponsivenessQ33652476
The bronchial epithelium as a key regulator of airway inflammation and remodelling in asthmaQ33696810
Airway remodeling and persistent airway obstruction in asthmaQ33731149
Signalling through the high-affinity IgE receptor Fc epsilonRI.Q33787609
Immunomodulatory mast cells: negative, as well as positive, regulators of immunityQ33791675
Human Mast cell progenitors can be infected by macrophagetropic human immunodeficiency virus type 1 and retain virus with maturation in vitroQ33848931
Mast cells in innate immunityQ33864393
Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsisQ33866102
Asthma. From bronchoconstriction to airways inflammation and remodelingQ33915771
IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell developmentQ33924669
Development of mast cells and importance of their tryptase and chymase serine proteases in inflammation and wound healingQ33969412
Immunoglobulin E signal inhibition during allergen ingestion leads to reversal of established food allergy and induction of regulatory T cellsQ34007974
Chronic allergen challenge induces bronchial mast cell accumulation in BALB/c but not C57BL/6 mice and is independent of IL-9.Q34021220
Functional specialization of interleukin-17 family membersQ34025860
Activating and inhibitory signaling in mast cells: new opportunities for therapeutic intervention?Q34030795
Peanut-induced intestinal allergy is mediated through a mast cell-IgE-FcepsilonRI-IL-13 pathwayQ34049963
Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthmaQ34052919
Contribution of classic and alternative effector pathways in peanut-induced anaphylactic responsesQ34110525
Asthma.Q34137112
A beneficial role for immunoglobulin E in host defense against honeybee venomQ34182028
Disparity in FcεRI-induced degranulation of primary human lung and skin mast cells exposed to adenosineQ36158473
Mast cell-airway smooth muscle crosstalk: the role of thymic stromal lymphopoietin.Q36163542
New IL-12-family members: IL-23 and IL-27, cytokines with divergent functionsQ36184396
Genetics of asthma susceptibility and severityQ36201283
The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsisQ36204127
Neutrophil histamine contributes to inflammation in mycoplasma pneumoniaQ36228230
Molecular mechanism of mast cell mediated innate defense against endothelin and snake venom sarafotoxinQ36229090
Mast cell deficiency in Kit(W-sh) mice does not impair antibody-mediated arthritisQ36229192
The rat c-kit ligand, stem cell factor, induces the development of connective tissue-type and mucosal mast cells in vivo. Analysis by anatomical distribution, histochemistry, and protease phenotypeQ36230164
Nerve growth factor induces development of connective tissue-type mast cells in vitro from murine bone marrow cellsQ36230188
Mast cells that reside at different locations in the jejunum of mice infected with Trichinella spiralis exhibit sequential changes in their granule ultrastructure and chymase phenotypeQ36237512
Cytological and pharmacological observations on the release of histamine by mast cellsQ36262432
Fc gamma RIIa, not Fc gamma RIIb, is constitutively and functionally expressed on skin-derived human mast cellsQ36330511
IgE-mediated release of leukotriene C4, chondroitin sulfate E proteoglycan, beta-hexosaminidase, and histamine from cultured bone marrow-derived mouse mast cellsQ36347367
Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosaQ36350812
Interleukin 3-dependent and -independent mast cells stimulated with IgE and antigen express multiple cytokinesQ36356540
Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in miceQ36368668
Modulation of immunoglobulin (Ig)E-mediated systemic anaphylaxis by low-affinity Fc receptors for IgG.Q36369947
Combined stimulation with the T helper cell type 2 cytokines interleukin (IL)-4 and IL-10 induces mouse mast cell apoptosisQ36376033
Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient miceQ36380426
The c-kit ligand, stem cell factor, can enhance innate immunity through effects on mast cellsQ36401371
Mast cells can secrete vascular permeability factor/ vascular endothelial cell growth factor and exhibit enhanced release after immunoglobulin E-dependent upregulation of fc epsilon receptor I expressionQ36401802
The mast cell and the cysteinyl leukotrienes.Q36444785
Mast cell-specific Cre/loxP-mediated recombination in vivoQ36498913
Tissue-selective mast cell reconstitution and differential lung gene expression in mast cell-deficient Kit(W-sh)/Kit(W-sh) sash miceQ36503050
IL-33 induces a hyporesponsive phenotype in human and mouse mast cells.Q36514301
Proliferation of peritoneal mast cells in the skin of W/Wv mice that genetically lack mast cellsQ36601792
New models for analyzing mast cell functions in vivoQ36610811
Asthma genetics and personalised medicineQ36622292
Approaches for analyzing the roles of mast cells and their proteases in vivoQ36630944
Evidence questioning cromolyn's effectiveness and selectivity as a 'mast cell stabilizer' in mice.Q36632214
New and emerging roles for mast cells in host defenceQ36663431
Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in miceQ36685067
μ-chain-deficient mice possess B-1 cells and produce IgG and IgE, but not IgA, following systemic sensitization and inhalational challenge in a fungal asthma modelQ42243852
Morphology of delayed-type hypersensitivity reactions in man. II. Ultrastructural alterations affecting the microvasculature and the tissue mast cellsQ42449158
Release of mast cell tryptase from human colorectal mucosa in inflammatory bowel diseaseQ42501267
Modulation of FcεRI-dependent mast cell response by OX40L via Fyn, PI3K, and RhoA.Q42505943
Localization of mucosal mast cells in W/Wv mice after reconstitution with bone marrow cells or cultured mast cells, and its relation to the protective capacity to Strongyloides ratti infectionQ42523719
Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synoviumQ42575994
A novel human immunoglobulin Fc gamma Fc epsilon bifunctional fusion protein inhibits Fc epsilon RI-mediated degranulationQ42796981
Expression and function of Fc gamma R in mouse mast cellsQ42828241
Mast cells protect mice from Mycoplasma pneumoniaQ42906117
Activation of human mast cells through the platelet-activating factor receptorQ43099465
Peanuts can contribute to anaphylactic shock by activating complement.Q43143999
Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammationQ43258635
An increase in circulating mast cell colony-forming cells in asthmaQ43545355
Inhibition of IgE-induced activation of human mast cells by IL-10.Q43650586
IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcepsilonRI signalsQ43690957
Human mast cell heterogeneity: histamine release from mast cells dispersed from skin, lung, adenoids, tonsils, and colon in response to IgE-dependent and nonimmunologic stimuliQ43692264
Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in miceQ43772453
Reconstitution of mucosal mast cells in W/WV mice by adoptive transfer of bone marrow-derived cultured mast cells and its effects on the protective capacity to Strongyloides ratti-infectionQ44015579
Activation of human mast cells through the high affinity IgG receptorQ44129017
IL-9 enhances the growth of human mast cell progenitors under stimulation with stem cell factorQ44368615
Platelet-activating factor, histamine, and tryptase levels in human anaphylaxisQ44520927
Mucosal mast cells are functionally active during spontaneous expulsion of intestinal nematode infections in rat.Q44624400
Increase of mucosal mast cells in the jejunum of patients infected with Trichinella spiralis.Q44748651
Stem cell factor contributes to intestinal mucosal mast cell hyperplasia in rats infected with Nippostrongylus brasiliensis or Trichinella spiralis, but anti-stem cell factor treatment decreases parasite egg production during N brasiliensis infectioQ44826803
Interleukin-10 induces apoptosis in developing mast cells and macrophagesQ44921665
Human mast cell carboxypeptidase. Selective localization to MCTC cells.Q44956967
Immunity to intestinal parasitesQ45018625
Detection of MCT and MCTC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodiesQ45024776
Secretion of interleukin-1 receptor antagonist from human mast cells after immunoglobulin E-mediated activation and after segmental antigen challengeQ45044608
The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infectionsQ45134515
Decreased susceptibility of mast cell-deficient Kit(W)/Kit(W-v) mice to the development of 1, 2-dimethylhydrazine-induced intestinal tumorsQ45254408
Virus-induced increases in bronchiolar mast cells in Brown Norway rats are associated with both local mast cell proliferation and increases in blood mast cell precursorsQ45789085
Mast cell chymase modulates IL-33 levels and controls allergic sensitization in dust-mite induced airway inflammation.Q45923646
Mast cells express IL-17A in rheumatoid arthritis synoviumQ46151437
A chimeric human-cat fusion protein blocks cat-induced allergyQ46483879
Mast cells play a critical role in the pathogenesis of viral myocarditisQ46497257
Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxisQ46700754
Distribution of chymase-containing mast cells in human bronchiQ46786736
Mast cell-derived tumour necrosis factor is essential for allergic airway disease.Q46840821
Impact of CD40 ligand, B cells, and mast cells in peanut-induced anaphylactic responsesQ46915133
Activation of mast cells by double-stranded RNA: evidence for activation through Toll-like receptor 3.Q47229699
Mast cells, Fc epsilon RI, and IL-13 are required for development of airway hyperresponsiveness after aerosolized allergen exposure in the absence of adjuvantQ47643921
Murine mast cells secrete a unique profile of cytokines and prostaglandins in response to distinct TLR2 ligandsQ47971946
Reversible expression of tryptases and chymases in the jejunal mast cells of mice infected with Trichinella spiralis.Q48032235
Natural disruption of the mouse mast cell protease 7 gene in the C57BL/6 mouseQ48066354
Attenuation of allergic airway inflammation in IL-4 deficient miceQ49112216
Quantitative assessment of intestinal eosinophils and mast cells in inflammatory bowel disease.Q50754207
Nafamostat mesilate attenuates colonic inflammation and mast cell infiltration in the experimental colitis.Q51525966
Substance P induces ion secretion in mouse small intestine through effects on enteric nerves and mast cells.Q51601001
Mast-cell infiltration of airway smooth muscle in asthma.Q51715332
Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesisQ34212866
Role of mast cells in ion transport abnormalities associated with intestinal anaphylaxis. Correction of the diminished secretory response in genetically mast cell-deficient W/Wv mice by bone marrow transplantationQ34238053
Interleukin 3: A differentiation and growth factor for the mouse mast cell that contains chondroitin sulfate E proteoglycanQ34250105
Mouse mast cell tryptase mMCP-6 is a critical link between adaptive and innate immunity in the chronic phase of Trichinella spiralis infectionQ34263777
Molecular editing of cellular responses by the high-affinity receptor for IgE.Q34301251
Assessing the evidence for remodelling of the airway in asthmaQ34305512
Quantitation of tryptase, chymase, Fc epsilon RI alpha, and Fc epsilon RI gamma mRNAs in human mast cells and basophils by competitive reverse transcription-polymerase chain reaction.Q34309355
Mast cells: function and contentsQ34340456
Mast cells promote homeostasis by limiting endothelin-1-induced toxicity.Q34367607
The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locusQ34407347
Distribution and degranulation of airway mast cells in normal and asthmatic subjectsQ34523433
Mast cells can enhance resistance to snake and honeybee venomsQ34551900
Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptorQ34567286
Effector and potential immunoregulatory roles of mast cells in IgE-associated acquired immune responsesQ34570242
Platelet-activating factor, PAF acetylhydrolase, and severe anaphylaxisQ34586645
IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity.Q34589849
Food allergy: recent advances in pathophysiology and treatment.Q34596150
CD4+CD25+ regulatory T cells suppress mast cell degranulation and allergic responses through OX40-OX40L interaction.Q34599954
Mast cells can promote the development of multiple features of chronic asthma in miceQ34619598
Anaphylaxis: lessons from mouse modelsQ34674225
Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B.Q34674471
W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activityQ34719633
Cutting edge: Helminth infection induces IgE in the absence of mu- or delta-chain expressionQ34732240
Mouse and human neutrophils induce anaphylaxis.Q34755391
Mast cell activators: a new class of highly effective vaccine adjuvantsQ34772018
G protein-dependent activation of mast cell by peptides and basic secretagoguesQ34786813
Compound 48/80: a potent histamine liberatorQ34790042
To B or not to B: B cells and the Th2-type immune response to helminthsQ34792884
Inhibitory receptors and allergyQ34987250
Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearanceQ35021816
Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammationQ35065323
Mast cells expressing chymase but not tryptase can be derived by culturing human progenitors in conditioned medium obtained from a human mastocytosis cell strain with c-kit ligandQ71120599
Stem cell factor enhances immunoglobulin E-dependent mediator release from cultured rat bone marrow-derived mast cells: activation of previously unresponsive cells demonstrated by a novel ELISPOT assayQ71235539
Activation of exocytosis by the heterotrimeric G protein Gi3Q71600439
Mucosal mast cell reconstitution and Nippostrongylus brasiliensis rejection by W/Wv miceQ71669121
Induction of the high-affinity IgE receptor (Fc epsilon RI) on human mast cells by IL-4Q71784302
Mast cells modulate allergic pulmonary eosinophilia in miceQ72108794
Decreased neutrophils and megakaryocytes in anemic mice of genotypeW/WvQ72340630
Mucosal mast cells. I. Isolation and functional characteristics of rat intestinal mast cellsQ72665504
Heterogeneity of mast cells at multiple body sites. Fluorescent determination of avidin binding and immunofluorescent determination of chymase, tryptase, and carboxypeptidase contentQ72807110
Interleukin-10 is localized to and released by human lung mast cellsQ73080012
Purification of mast cell proteases from murine skinQ73120614
Histamine in tissue mast cellsQ73274837
Mucosal mast cell responses are not required for protection against infection with the murine nematode parasite Trichuris murisQ73294349
The incidence and management of infusion reactions to infliximab: a large center experienceQ73555726
An essential role of mast cells in the development of airway hyperresponsiveness in a murine asthma modelQ73567370
Expression of a functional high-affinity IgG receptor, Fc gamma RI, on human mast cells: Up-regulation by IFN-gammaQ73644548
Human mast cells transmigrate through human umbilical vein endothelial monolayers and selectively produce IL-8 in response to stromal cell-derived factor-1 alphaQ73910743
Human mast cell tryptase stimulates the release of an IL-8-dependent neutrophil chemotactic activity from human umbilical vein endothelial cells (HUVEC)Q73968538
Interleukin-4 promotes the development of tryptase and chymase double-positive human mast cells accompanied by cell maturationQ73981951
Role for interleukin-3 in mast-cell and basophil development and in immunity to parasitesQ74336756
Role of Janus kinase 3 in mast cell-mediated innate immunity against gram-negative bacteriaQ74419766
Direct evidence of mast cell involvement in Clostridium difficile toxin A-induced enteritis in miceQ74477573
The role of mast cell tryptase in regulating endothelial cell proliferation, cytokine release, and adhesion molecule expression: tryptase induces expression of mRNA for IL-1 beta and IL-8 and stimulates the selective release of IL-8 from human umbilQ77123470
Resident cardiac mast cells degranulate and release preformed TNF-alpha, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusionQ77142325
Involvement of mast cells in IL-12/23 p40 production is essential for survival from polymicrobial infectionsQ79749968
Human mast cells are capable of serotonin synthesis and releaseQ79755078
Cutting edge: The ST2 ligand IL-33 potently activates and drives maturation of human mast cellsQ80736011
Generation and characterization of alpha-chymase-Cre transgenic miceQ80839134
Smad3 deficiency in mast cells provides efficient host protection against acute septic peritonitisQ81546541
Mast cells enhance T cell activation: importance of mast cell costimulatory molecules and secreted TNFQ82459138
Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-sponsored expert panel reportQ83395014
Genetic variation determines mast cell functions in experimental asthmaQ84102352
Mast cell tryptase levels in gut mucosa in patients with gastrointestinal symptoms caused by food allergyQ85537964
Mast cells contribute to bleomycin-induced lung inflammation and injury in mice through a chymase/mast cell protease 4-dependent mechanismQ87147961
Activation of human synovial mast cells from rheumatoid arthritis or osteoarthritis patients in response to aggregated IgG through Fcγ receptor I and Fcγ receptor IIQ87426506
Mast cells are activated by Staphylococcus aureus in vitro but do not influence the outcome of intraperitoneal S. aureus infection in vivoQ87578686
Effect of Mg2+ and ATP on depolarization-induced Ca2+ release in isolated triadsQ93864719
Pathogenesis of steroid-resistant airway hyperresponsiveness: interaction between IFN-gamma and TLR4/MyD88 pathways.Q51738108
Basophils protect against reinfection with hookworms independently of mast cells and memory Th2 cells.Q51888680
CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma.Q36691117
Aryl hydrocarbon receptor controls murine mast cell homeostasisQ36779431
Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakageQ36804428
Mast cells and eicosanoid mediators: a system of reciprocal paracrine and autocrine regulationQ36819905
The mast cell IgG receptors and their roles in tissue inflammationQ36819920
Regulation of the mast cell response to the type 1 Fc epsilon receptor.Q36819928
Mast cells in the promotion and limitation of chronic inflammation.Q36819950
Mast cell interleukin-10 drives localized tolerance in chronic bladder infectionQ36826092
Synthesis, storage, and release of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) by human mast cells: implications for the biological significance of VEGF206.Q36866179
Mast cell proteasesQ36942528
Genetic inversion in mast cell-deficient (Wsh) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy.Q37061078
Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33.Q37100750
Delayed expulsion of adult Trichinella spiralis by mast cell-deficient W/Wv miceQ37110194
Food allergy in children suffering from atopic eczemaQ37132359
Adenosine and inosine increase cutaneous vasopermeability by activating A(3) receptors on mast cellsQ37175389
Efficient cytokine-induced IL-13 production by mast cells requires both IL-33 and IL-3Q37196946
Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice.Q37224997
New insights on mast cell activation via the high affinity receptor for IgEQ37260865
Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in miceQ37330834
Mast cells suppress murine GVHD in a mechanism independent of CD4+CD25+ regulatory T cellsQ37334737
Absence of Fc epsilonRI alpha chain results in upregulation of Fc gammaRIII-dependent mast cell degranulation and anaphylaxis. Evidence of competition between Fc epsilonRI and Fc gammaRIII for limiting amounts of FcR beta and gamma chainsQ37364326
Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cellsQ37365477
Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunityQ37367152
Factor Xa as an interface between coagulation and inflammation. Molecular mimicry of factor Xa association with effector cell protease receptor-1 induces acute inflammation in vivoQ37367555
Regulation of pathogenesis and immunity in helminth infectionsQ37377434
Mast cell-derived particles deliver peripheral signals to remote lymph nodesQ37402380
Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cellsQ37435599
Interleukin 4 promotes expression of mast cell ICAM-1 antigenQ37484203
Physiological and pathophysiological functions of intestinal mast cellsQ37521998
Food-induced anaphylaxis: mast cells as modulators of anaphylactic severityQ37585269
Distinct cellular origins for serotonin-expressing and enterochromaffin-like cells in the gastric corpusQ37620107
Advances in mast cell biology: new understanding of heterogeneity and functionQ37665290
Disease-associated functions of IL-33: the new kid in the IL-1 familyQ37676926
P433issue3
P921main subjectmast cellQ191989
P304page(s)444-463
P577publication date2015-02-11
P1433published inMucosal ImmunologyQ15817743
P1476titlePotential effector and immunoregulatory functions of mast cells in mucosal immunity
P478volume8

Reverse relations

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