Mast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokines

scientific article published on 9 April 2012

Mast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokines is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2012PNAS..109.6644H
P356DOI10.1073/PNAS.1112268109
P932PMC publication ID3340035
P698PubMed publication ID22493240
P5875ResearchGate publication ID223974607

P50authorMartin MetzQ37838546
Matthew R. HepworthQ47138420
Marcus MaurerQ50039778
P2093author name stringSebastian Rausch
Susanne Hartmann
Christian Klotz
Emilia Daniłowicz-Luebert
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Nuocytes represent a new innate effector leukocyte that mediates type-2 immunityQ24630261
IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responsesQ24630608
Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tractQ24673592
Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsionQ24676901
Mast cells produce interleukin-25 upon Fc epsilon RI-mediated activationQ28201578
IL-33, a potent inducer of adaptive immunity to intestinal nematodesQ28505946
Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cellsQ29619771
IL-33 augments substance P-induced VEGF secretion from human mast cells and is increased in psoriatic skinQ33732911
Mast cells elicit proinflammatory but not type I interferon responses upon activation of TLRs by bacteriaQ33928533
Critical role of IL-25 in nematode infection-induced alterations in intestinal function.Q34332461
Mast cells promote homeostasis by limiting endothelin-1-induced toxicity.Q34367607
IL-9- and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity.Q34589849
Thymic stromal lymphopoietin fosters human breast tumor growth by promoting type 2 inflammationQ34681491
TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammationQ35686590
Mast cell-derived TNF can promote Th17 cell-dependent neutrophil recruitment in ovalbumin-challenged OTII miceQ35804444
Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity.Q36157993
The mast cell and gut nematodes: damage and defenceQ36279702
IL-33 exacerbates antigen-induced arthritis by activating mast cellsQ36800502
Commensal-dependent expression of IL-25 regulates the IL-23-IL-17 axis in the intestine.Q36916407
Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sitesQ37195506
TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis.Q37234277
MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity.Q37263947
Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell functionQ37310695
Mast cells: makers and breakers of allergic inflammationQ37529040
Localization of mucosal mast cells in W/Wv mice after reconstitution with bone marrow cells or cultured mast cells, and its relation to the protective capacity to Strongyloides ratti infectionQ42523719
Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cellsQ42767760
TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand.Q42972510
RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiotaQ46167903
Cortical excitatory amino acid release and cell function during hypotension in near-term born lambsQ48596189
Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths.Q51038494
Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasisQ59053989
Mast Cells Are Key Promoters of Contact Allergy that Mediate the Adjuvant Effects of HaptensQ59404503
Blocking IL-25 prevents airway hyperresponsiveness in allergic asthmaQ81339821
Mast cell-associated TNF promotes dendritic cell migrationQ82878867
Mast cell production of IL-4 and TNF may be required for protective and pathological responses in gastrointestinal helminth infectionQ82949677
The human cytokine TSLP triggers a cell-autonomous dendritic cell migration in confined environmentsQ84576362
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectmast cellQ191989
P304page(s)6644-6649
P577publication date2012-04-09
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleMast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokines
P478volume109

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