| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/JLB.3MIR0817-340R |
| P698 | PubMed publication ID | 29345374 |
| P50 | author | Laura M Sly | Q42412672 |
| P2093 | author name string | Peter Dobranowski | |
| P2860 | cites work | The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase | Q24567715 |
| Inositol phosphatase SHIP1 is a primary target of miR-155 | Q24648984 | ||
| Mast cells and IgE in defense against venoms: Possible "good side" of allergy? | Q26775969 | ||
| The phosphoinositide 3-kinase pathway | Q27860738 | ||
| Synthesis and function of 3-phosphorylated inositol lipids | Q28200755 | ||
| p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity | Q28280824 | ||
| AQX-1125, small molecule SHIP1 activator inhibits bleomycin-induced pulmonary fibrosis | Q48208455 | ||
| Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths. | Q51038494 | ||
| SHIP-deficient, alternatively activated macrophages protect mice during DSS-induced colitis. | Q52612704 | ||
| Activity of SHIP, Which Prevents Expression of Interleukin 1β, Is Reduced in Patients With Crohn's Disease. | Q52908658 | ||
| A pleckstrin homology-related domain in SHIP1 mediates membrane localization during Fcγ receptor-induced phagocytosis. | Q53108933 | ||
| Basophil FcepsilonRI histamine release parallels expression of Src-homology 2-containing inositol phosphatases in chronic idiopathic urticaria. | Q53586630 | ||
| Lineage-specific regulation of allergic airway inflammation by the lipid phosphatase Src homology 2 domain-containing inositol 5-phosphatase (SHIP-1). | Q53592135 | ||
| Initial Fc epsilon RI-mediated signal strength plays a key role in regulating basophil signaling and deactivation. | Q53895687 | ||
| s-SHIP associates with receptor complexes essential for pluripotent stem cell growth and survival. | Q54571565 | ||
| Alternative activation of macrophages by IL-4 requires SHIP degradation. | Q54598466 | ||
| Selective in vivo recruitment of the phosphatidylinositol phosphatase SHIP by phosphorylated FcγRIIB during negative regulation of IgE-dependent mouse mast cell activation | Q56966704 | ||
| Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation | Q57253538 | ||
| Intestinal expression of SHIP in inflammatory bowel diseases | Q57265341 | ||
| PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells | Q42811887 | ||
| Cloning of the genomic locus of mouse SH2 containing inositol 5-phosphatase (SHIP) and a novel 110-kDa splice isoform, SHIPdelta | Q42835414 | ||
| The role of SHIP in the development and activation of mouse mucosal and connective tissue mast cells | Q43215710 | ||
| SHIP represses the generation of IL-3-induced M2 macrophages by inhibiting IL-4 production from basophils. | Q43285258 | ||
| Src homology 2 domain-containing inositol 5' phosphatase is negatively associated with histamine release to human recombinant histamine-releasing factor in human basophils | Q43787633 | ||
| Downstream of kinase, p62(dok), is a mediator of Fc gamma IIB inhibition of Fc epsilon RI signaling | Q43968795 | ||
| Arginase activity in alternatively activated macrophages protects PI3Kp110δ deficient mice from dextran sodium sulfate induced intestinal inflammation | Q44086481 | ||
| The effects of the novel SHIP1 activator AQX-1125 on allergen-induced responses in mild-to-moderate asthma. | Q44102880 | ||
| The Src homology 2 domain-containing inositol 5-phosphatase negatively regulates Fcgamma receptor-mediated phagocytosis through immunoreceptor tyrosine-based activation motif-bearing phagocytic receptors | Q44182949 | ||
| Dendritic cell immunoreceptor: a novel receptor for intravenous immunoglobulin mediates induction of regulatory T cells | Q44572608 | ||
| Intravenous immunoglobulin skews macrophages to an anti-inflammatory, IL-10-producing activation state | Q44680490 | ||
| Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells | Q45228618 | ||
| Src homology 2 domain-containing inositol-5-phosphatase 1 (SHIP1) negatively regulates TLR4-mediated LPS response primarily through a phosphatase activity- and PI-3K-independent mechanism | Q45258166 | ||
| Inhibitory receptor FcγRIIb mediates the effects of IgG on a phagosome acidification and a sequential dephosphorylation system comprising SHIPs and Inpp4a | Q46383203 | ||
| SHIP represses the generation of alternatively activated macrophages | Q46754459 | ||
| Signaling by the phosphoinositide 3-kinase family in immune cells | Q28283677 | ||
| Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2 | Q28285431 | ||
| Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate | Q28301966 | ||
| SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts | Q28510858 | ||
| Abolition of anaphylaxis by targeted disruption of the high affinity immunoglobulin E receptor alpha chain gene | Q28588495 | ||
| Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span | Q28590421 | ||
| Shc interaction with Src homology 2 domain containing inositol phosphatase (SHIP) in vivo requires the Shc-phosphotyrosine binding domain and two specific phosphotyrosines on SHIP | Q28609044 | ||
| Macrophage activation and polarization | Q29616353 | ||
| Protective and pathogenic functions of macrophage subsets | Q29620351 | ||
| Regulation of the Src homology 2 domain-containing inositol 5'-phosphatase (SHIP1) by the cyclic AMP-dependent protein kinase | Q30435403 | ||
| SHIP-1 increases early oxidative burst and regulates phagosome maturation in macrophages | Q30495822 | ||
| Macrophage pro-inflammatory response to Francisella novicida infection is regulated by SHIP. | Q33250568 | ||
| Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor | Q33335777 | ||
| Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease | Q33347581 | ||
| Infusion of Fc gamma fragments for treatment of children with acute immune thrombocytopenic purpura. | Q33492203 | ||
| Differential roles for the inositol phosphatase SHIP in the regulation of macrophages and lymphocytes | Q33596651 | ||
| SHIP1 inhibition increases immunoregulatory capacity and triggers apoptosis of hematopoietic cancer cells. | Q34008167 | ||
| Lipid phosphatases in the immune system | Q34038115 | ||
| Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc gamma RIIB1. | Q34308479 | ||
| The inositol phosphatase SHIP-1 inhibits NOD2-induced NF-κB activation by disturbing the interaction of XIAP with RIP2. | Q34345519 | ||
| Of ITIMs, ITAMs, and ITAMis: revisiting immunoglobulin Fc receptor signaling. | Q34499276 | ||
| Phosphoinositide 3-kinase in immunological systems | Q34555099 | ||
| Oral immunotherapy induces IgG antibodies that act through FcγRIIb to suppress IgE-mediated hypersensitivity | Q34664144 | ||
| SHIP-deficient mice develop spontaneous intestinal inflammation and arginase-dependent fibrosis | Q35070179 | ||
| Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation | Q35083309 | ||
| Altered expression of SHIP, a Toll-like receptor pathway inhibitor, is associated with the severity of liver fibrosis in chronic hepatitis C virus infection | Q35214136 | ||
| Balanced interactions between Lyn, the p85alpha regulatory subunit of class I(A) phosphatidylinositol-3-kinase, and SHIP are essential for mast cell growth and maturation | Q35274032 | ||
| Therapeutic potential of SH2 domain-containing inositol-5'-phosphatase 1 (SHIP1) and SHIP2 inhibition in cancer | Q35718988 | ||
| Human FcγRIIA induces anaphylactic and allergic reactions | Q35849322 | ||
| Mast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokines | Q35921836 | ||
| Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils | Q36141195 | ||
| All Trans Retinoic Acid, Transforming Growth Factor β and Prostaglandin E2 in Mouse Plasma Synergize with Basophil-Secreted Interleukin-4 to M2 Polarize Murine Macrophages | Q36224968 | ||
| The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation | Q36310121 | ||
| A regulatory role for Src homology 2 domain-containing inositol 5'-phosphatase (SHIP) in phagocytosis mediated by Fc gamma receptors and complement receptor 3 (alpha(M)beta(2); CD11b/CD18) | Q36376113 | ||
| Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1. | Q36380184 | ||
| Distinct characteristics of signal transduction events by histamine-releasing factor/translationally controlled tumor protein (HRF/TCTP)-induced priming and activation of human basophils | Q36445792 | ||
| Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung | Q36591321 | ||
| Characterization of AQX-1125, a small-molecule SHIP1 activator: Part 1. Effects on inflammatory cell activation and chemotaxis in vitro and pharmacokinetic characterization in vivo | Q36681799 | ||
| The inositol phosphatase SHIP controls Salmonella enterica serovar Typhimurium infection in vivo | Q36747127 | ||
| SHIP represses lung inflammation and inhibits mammary tumor metastasis in BALB/c mice. | Q36782245 | ||
| SH2 Domains Serve as Lipid-Binding Modules for pTyr-Signaling Proteins | Q36782828 | ||
| The mast cell IgG receptors and their roles in tissue inflammation | Q36819920 | ||
| Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway. | Q36959840 | ||
| Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7 | Q37081321 | ||
| SHIP prevents lipopolysaccharide from triggering an antiviral response in mice | Q37143647 | ||
| Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages. | Q37337400 | ||
| The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease | Q37409519 | ||
| Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-beta-dependent pathways and increases expression of negative regulators of TLR signaling | Q37486509 | ||
| MicroRNA-155 promotes the pathogenesis of experimental colitis by repressing SHIP-1 expression | Q37644020 | ||
| Role of SHIP in cancer | Q37807646 | ||
| Inhibitor and activator: dual functions for SHIP in immunity and cancer | Q37820689 | ||
| SHIP-mediated inhibition of K562 erythroid differentiation requires an intact catalytic domain and Shc binding site | Q38317552 | ||
| The Dok-3/Grb2 adaptor module promotes inducible association of the lipid phosphatase SHIP with the BCR in a coreceptor-independent manner | Q38733606 | ||
| Regulation of immune cell signaling by SHIP1: A phosphatase, scaffold protein, and potential therapeutic target. | Q38799014 | ||
| Trans-inhibition of activation and proliferation signals by Fc receptors in mast cells and basophils. | Q39080424 | ||
| BCR/ABL directly inhibits expression of SHIP, an SH2-containing polyinositol-5-phosphatase involved in the regulation of hematopoiesis | Q39448485 | ||
| Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections | Q39457934 | ||
| SHIP represses Th2 skewing by inhibiting IL-4 production from basophils | Q39623829 | ||
| Tyrosine phosphorylation of SHIP promotes its proteasomal degradation. | Q39725389 | ||
| Absence of SHIP-1 results in constitutive phosphorylation of tank-binding kinase 1 and enhanced TLR3-dependent IFN-beta production | Q39748042 | ||
| Genetic segregation of inflammatory lung disease and autoimmune disease severity in SHIP-1-/- mice | Q39750161 | ||
| Induction of endotoxin tolerance in vivo inhibits activation of IRAK4 and increases negative regulators IRAK-M, SHIP-1, and A20. | Q39753707 | ||
| Differences in the Importance of Mast Cells, Basophils, IgE, and IgG versus That of CD4+ T Cells and ILC2 Cells in Primary and Secondary Immunity to Strongyloides venezuelensis | Q40306118 | ||
| Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors. | Q40342009 | ||
| SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival | Q40443155 | ||
| The Crohn's disease-associated polymorphism in ATG16L1 (rs2241880) reduces SHIP gene expression and activity in human subjects. | Q40678107 | ||
| The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells | Q40831487 | ||
| Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals | Q41037034 | ||
| The inositol 5'-phosphatase SHIP binds to immunoreceptor signaling motifs and responds to high affinity IgE receptor aggregation | Q41151188 | ||
| Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB. | Q41166947 | ||
| Analysis of SHIP1 expression and activity in Crohn's disease patients | Q41216635 | ||
| The Role of Cytokines in the Fibrotic Responses in Crohn's Disease | Q41273741 | ||
| Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells. | Q41812650 | ||
| Impaired T-cell survival promotes mucosal inflammatory disease in SHIP1-deficient mice | Q41842794 | ||
| SHIP deficiency causes Crohn's disease-like ileitis | Q42072927 | ||
| P921 | main subject | mast cell | Q191989 |
| P577 | publication date | 2018-01-17 | |
| P1433 | published in | Journal of Leukocyte Biology | Q1524048 |
| P1476 | title | SHIP negatively regulates type II immune responses in mast cells and macrophages |
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