Disease-associated functions of IL-33: the new kid in the IL-1 family

scientific article published on 18 January 2010

Disease-associated functions of IL-33: the new kid in the IL-1 family is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1038/NRI2692
P698PubMed publication ID20081870

P50authorIain McInnesQ41687181
P2093author name stringFoo Y Liew
Nick I Pitman
P2860cites workIL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokinesQ24294720
IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammationQ24309034
Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 proteinQ24314282
Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A-H2B acidic pocketQ24321867
Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's diseaseQ24631387
HMGB1: endogenous danger signalingQ24645232
A novel IL-1 family cytokine, IL-33, potently activates human eosinophilsQ24647672
The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1Q24651453
T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector functionQ24651566
Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venulesQ24685626
Release of chromatin protein HMGB1 by necrotic cells triggers inflammationQ28131815
IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complexQ28239351
Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophilsQ28292740
IL-33, a potent inducer of adaptive immunity to intestinal nematodesQ28505946
IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cellsQ28513686
IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling systemQ28585033
Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammationQ28586791
IL-33 reduces the development of atherosclerosisQ28594104
DAMPs, PAMPs and alarmins: all we need to know about dangerQ29547535
Identification of genes differentially expressed in canine vasospastic cerebral arteries after subarachnoid hemorrhageQ30814887
The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel 'alarmin'?Q33374001
Increased expression of IL-33 in severe asthma: evidence of expression by airway smooth muscle cellsQ33508406
The effect of ST2 gene product on anchorage-independent growth of a glioblastoma cell line, T98G.Q34166051
Identification of serum soluble ST2 receptor as a novel heart failure biomarkerQ34176448
Expression and regulation of ST2, an interleukin-1 receptor family member, in cardiomyocytes and myocardial infarctionQ34603397
IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivoQ35575987
Alarmins: chemotactic activators of immune responsesQ36162859
Inhibition of T1/ST2 during respiratory syncytial virus infection prevents T helper cell type 2 (Th2)- but not Th1-driven immunopathologyQ36369101
Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cellsQ36400414
IL-33 mediates antigen-induced cutaneous and articular hypernociception in miceQ36497523
Induction of a mitogen-responsive gene after expression of the Ha-ras oncogene in NIH 3T3 fibroblastsQ36796387
IL-33 exacerbates antigen-induced arthritis by activating mast cellsQ36800502
Induction of IL-33 expression and activity in central nervous system gliaQ36838536
Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomesQ37000186
Resolution of allergic inflammation and airway hyperreactivity is dependent upon disruption of the T1/ST2-IL-33 pathwayQ37175226
IL-1, IL-18, and IL-33 families of cytokinesQ37211243
The cytokine interleukin-33 mediates anaphylactic shockQ37238924
Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesisQ37255168
IL-33-activated dendritic cells induce an atypical TH2-type responseQ37265087
Interleukin-33 is biologically active independently of caspase-1 cleavageQ37339298
Mature interleukin-33 is produced by calpain-mediated cleavage in vivoQ39825950
IL-33 enhances lipopolysaccharide-induced inflammatory cytokine production from mouse macrophages by regulating lipopolysaccharide receptor complexQ39833597
TRAF6 is a critical signal transducer in IL-33 signaling pathwayQ39964682
Interleukin (IL)-33 induces the release of pro-inflammatory mediators by mast cellsQ40049209
Cutting edge: critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1 alpha released from dying cellsQ42584586
Identification of a nuclear localization sequence within the structure of the human interleukin-1 alpha precursor.Q42617785
Presence of a novel primary response gene ST2L, encoding a product highly similar to the interleukin 1 receptor type 1.Q42693160
A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptorQ42834513
Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses.Q42947124
The absence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector functionQ42947210
IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcepsilonRI signalsQ43690957
Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases.Q44030778
Serum levels of the interleukin-1 receptor family member ST2 predict mortality and clinical outcome in acute myocardial infarctionQ44245130
IL-33 induces antigen-specific IL-5+ T cells and promotes allergic-induced airway inflammation independent of IL-4.Q45067212
An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptorQ46305097
A novel therapy of murine collagen-induced arthritis with soluble T1/ST2.Q47310105
Role of cell type-specific promoters in the developmental regulation of T1, an interleukin 1 receptor homologue.Q48075198
The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-gamma production.Q51780702
IL-33 is a chemoattractant for human Th2 cells.Q53528244
IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells.Q54421098
Tissue Distribution and Subcellular Localization of a Variant Form of the Human ST2 Gene Product, ST2VQ56593773
IL-33 can promote survival, adhesion and cytokine production in human mast cellsQ57273112
Mast cells modulate allergic pulmonary eosinophilia in miceQ72108794
T1/ST2 expression on Th2 cells negatively regulates allergic pulmonary inflammationQ80094797
Cutting edge: The ST2 ligand IL-33 potently activates and drives maturation of human mast cellsQ80736011
Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune systemQ81191920
Elevation of ST2 protein levels in cerebrospinal fluid following subarachnoid hemorrhageQ83185001
Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritisQ83398961
Anti-IL-33 antibody treatment inhibits airway inflammation in a murine model of allergic asthmaQ84030123
P433issue2
P304page(s)103-110
P577publication date2010-01-18
P1433published inNature Reviews ImmunologyQ43355
P1476titleDisease-associated functions of IL-33: the new kid in the IL-1 family
P478volume10

Reverse relations

cites work (P2860)
Q3390481425-Hydroxyvitamin D, IL-31, and IL-33 in children with allergic disease of the airways
Q37658912A mechanism for the induction of type 2 immune responses by a protease allergen in the genital tract
Q97550316A new dawn for eosinophils in the tumour microenvironment
Q39648956A novel method for procuring a large quantity of mature murine eosinophils in vivo
Q35803472A single-nucleotide polymorphism in the interleukin-1 receptor-associated protein gene is associated with impaired glucose regulation and type 2 diabetes in a case-controlled study
Q35699580AMCase is a crucial regulator of type 2 immune responses to inhaled house dust mites
Q58234722Ability of Interleukin-33- and Immune Complex-Triggered Activation of Human Mast Cells to Down-Regulate Monocyte-Mediated Immune Responses
Q51684114Ablation of interaction between IL-33 and ST2+ regulatory T cells increases immune cell-mediated hepatitis and activated NK cell liver infiltration.
Q36744984Activated mast cells synthesize and release soluble ST2-a decoy receptor for IL-33.
Q34137362Activation of eosinophils interacting with dermal fibroblasts by pruritogenic cytokine IL-31 and alarmin IL-33: implications in atopic dermatitis
Q35631650Additive anti-allergic effects of anti-interleukin-33 and anti-Siglec-F treatments in a murine model of allergic asthma
Q92116878Adjuvantic cytokine IL-33 improves the protective immunity of cocktailed DNA vaccine of ROP5 and ROP18 against toxoplasma gondii infection in mice
Q36871145Airway molecular endotypes of asthma: dissecting the heterogeneity
Q34033407Alarmin IL-33 acts as an immunoadjuvant to enhance antigen-specific tumor immunity
Q30375869Alarmin IL-33 elicits potent TB-specific cell-mediated responses.
Q38845953Alarmins and Their Receptors as Modulators and Indicators of Alloimmune Responses
Q38245926Allergen immunotherapy, routes of administration and cytokine networks: an update
Q93000694Alteration of the IL-33-sST2 pathway in hypertensive patients and a mouse model
Q36445023Altered serum levels of IL-33 in patients with advanced systolic chronic heart failure: correlation with oxidative stress
Q33589491Alzheimer's disease: evidence for the expression of interleukin-33 and its receptor ST2 in the brain
Q28652444Ambient particulate matter induces an exacerbation of airway inflammation in experimental asthma: role of interleukin-33
Q34895161Amplification of cytokine production through synergistic activation of NFAT and AP-1 following stimulation of mast cells with antigen and IL-33
Q52331711An Inflammation-Centric View of Neurological Disease: Beyond the Neuron.
Q47701304An Update on Host-Pathogen Interplay and Modulation of Immune Responses during Orientia tsutsugamushi Infection.
Q38912837An increase of interleukin-33 serum levels after coronary stent implantation is associated with coronary in-stent restenosis
Q42819258An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice
Q48283294Anti-IL-33 Antibody Has a Therapeutic Effect in an Atopic Dermatitis Murine Model Induced by 2, 4-Dinitrochlorobenzene
Q38381344Anti-allergic properties of curine, a bisbenzylisoquinoline alkaloid.
Q44941485Anti-interleukin-33 inhibits cigarette smoke-induced lung inflammation in mice
Q30415188Apoptotic cell clearance by bronchial epithelial cells critically influences airway inflammation
Q90480978Association between interleukin-36γ and tumor progression in non-small cell lung cancer
Q86710783Association of IL33/ST2 signal pathway gene polymorphisms with myocardial infarction in a Chinese Han population
Q53194504Association of soluble ST2 with functional capacity in outpatients with heart failure.
Q34835415Associations between variants in IL-33/ST2 signaling pathway genes and coronary heart disease risk
Q34304314Basophil modulation by cytokine instruction
Q38830074Basophil-derived IL-4 plays versatile roles in immunity.
Q33808159Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation
Q84977996Blockade of IL-33 ameliorates Con A-induced hepatic injury by reducing NKT cell activation and IFN-γ production in mice
Q39465399Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy.
Q42538647Brief Report: Proatherogenic Cytokine Microenvironment in the Aortic Adventitia of Patients With Rheumatoid Arthritis
Q49973003CD300 family receptors regulate eosinophil survival, chemotaxis, and effector functions
Q93261627Cancer cell-derived interleukin-33 decoy receptor sST2 enhances orthotopic tumor growth in a murine pancreatic cancer model
Q38572500Candidate biomarkers in heart failure with reduced and preserved ejection fraction
Q35658781Cardiovascular biomarkers in acute Kawasaki disease
Q41464455Caspase-1 activation by NLRP3 inflammasome dampens IL-33-dependent house dust mite-induced allergic lung inflammation
Q34520488Caspase-1 regulates autoinflammation in rheumatic diseases
Q26748487Cell Culture, Technology: Enhancing the Culture of Diagnosing Human Diseases
Q34442444Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells
Q34155912Chronic low dose chlorine exposure aggravates allergic inflammation and airway hyperresponsiveness and activates inflammasome pathway
Q37499617Chronic proliferative dermatitis in Sharpin null mice: development of an autoinflammatory disease in the absence of B and T lymphocytes and IL4/IL13 signaling
Q34504507Chronic spontaneous urticaria and internal parasites--a systematic review.
Q60045482Circulating levels of IL-1 family cytokines and receptors in Alzheimer's disease: new markers of disease progression?
Q38235148Classical versus alternative macrophage activation: the Ying and the Yang in host defense against pulmonary fungal infections
Q40687007Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine-driven inflammation and fibrosis
Q47661265Comparative Study of IL-33 and IL-6 Levels in Different Respiratory Samples in Mild-to-Moderate Asthma and COPD.
Q34807329Comparative study of the cytokine/chemokine response in children with differing disease severity in enterovirus 71-induced hand, foot, and mouth disease
Q42156210Components of the interleukin-33/ST2 system are differentially expressed and regulated in human cardiac cells and in cells of the cardiac vasculature
Q36396910Computational analysis of multimorbidity between asthma, eczema and rhinitis
Q35886682Conformational Sampling and Binding Site Assessment of Suppression of Tumorigenicity 2 Ectodomain
Q42123554Constitutive interferon-inducible protein 16-inflammasome activation during Epstein-Barr virus latency I, II, and III in B and epithelial cells
Q54213225Controlling Mast Cell Activation and Homeostasis: Work Influenced by Bill Paul That Continues Today.
Q37996923Cross-roads in the lung: immune cells and tissue interactions as determinants of allergic asthma
Q30749968Cross-species evidence for the role of interleukin-33 in depression risk
Q35439783Crucial and diverse role of the interleukin-33/ST2 axis in infectious diseases
Q93095137Current perspectives on the interleukin-1 family as targets for inflammatory disease
Q55025675Cyclic AMP signaling enhances lipopolysaccharide sensitivity and interleukin-33 production in RAW264.7 macrophages.
Q37981059Cytokine pathways in allergic disease
Q26752374Cytokine-Induced Modulation of Colorectal Cancer
Q35861150Cytokine-Mediated Activation of NK Cells during Viral Infection
Q91636313Cytokines and beyond: Regulation of innate immune responses during helminth infection
Q35828345DNA methylation and childhood asthma in the inner city
Q37695034Damage-associated molecular patterns stimulate interleukin-33 expression in nasal polyp epithelial cells
Q38025082Danger signals activating the immune response after trauma
Q37965363Deciphering the structure and function of FcεRI/mast cell axis in the regulation of allergy and anaphylaxis: a functional genomics paradigm.
Q36994635Decoys and Regulatory "Receptors" of the IL-1/Toll-Like Receptor Superfamily
Q52655292Dectin-1 stimulates IL-33 expression in dendritic cells via upregulation of IRF4.
Q34428400Deletion of IL-33R (ST2) abrogates resistance to EAE in BALB/C mice by enhancing polarization of APC to inflammatory phenotype
Q34121429Deubiquitination and stabilization of IL-33 by USP21.
Q41810665Dietary galacto-oligosaccharides prevent airway eosinophilia and hyperresponsiveness in a murine house dust mite-induced asthma model.
Q38112683Different Members of the IL-1 Family Come Out in Different Ways: DAMPs vs. Cytokines?
Q34540500Disordered IL-33/ST2 activation in decidualizing stromal cells prolongs uterine receptivity in women with recurrent pregnancy loss
Q47449977Double-stranded RNA released from damaged articular chondrocytes promotes cartilage degeneration via Toll-like receptor 3-interleukin-33 pathway.
Q38956279Doyne lecture 2016: intraocular health and the many faces of inflammation
Q35904651Dysbiosis-induced IL-33 contributes to impaired antiviral immunity in the genital mucosa
Q37748500Early detection of myocardial dysfunction and heart failure
Q52655629Early-life exposure to three size-fractionated ultrafine and fine atmospheric particulates in Beijing exacerbates asthma development in mature mice.
Q38189119Effector and regulatory T cell subsets in diabetes-associated inflammation. Is there a connection with ST2/IL-33 axis? Perspective.
Q37860121Effects of Panax ginseng on tumor necrosis factor-α-mediated inflammation: a mini-review.
Q92382296Effects of Tocilizumab Therapy on Serum Interleukin-33 and Interleukin-6 Levels in Patients With Rheumatoid Arthritis
Q38919984Effects of obesity on IL-33/ST2 system in heart, adipose tissue and liver: study in the experimental model of Zucker rats.
Q37363858Elevated ST2 Distinguishes Incidences of Pediatric Heart and Small Bowel Transplant Rejection
Q34446837Elevated antigen-driven IL-9 responses are prominent in peanut allergic humans
Q87359693Elevated circulating sST2 associated with subclinical atherosclerosis in newly diagnosed primary hypertension
Q43688310Elevated serum interleukin-33 levels in patients with Henoch-Schönlein purpura
Q38774563Emerging concepts: mast cell involvement in allergic diseases.
Q38151715Emerging role of interleukin-33 in autoimmune diseases
Q96951726Engineering immunomodulatory biomaterials for type 1 diabetes
Q36762460Eosinophil adoptive transfer system to directly evaluate pulmonary eosinophil trafficking in vivo
Q45051460Epidermal inactivation of the glucocorticoid receptor triggers skin barrier defects and cutaneous inflammation
Q91675729Epithelial barrier repair and prevention of allergy
Q38198788Epithelial function and dysfunction in asthma.
Q34425901Epithelial interleukin-25 is a key mediator in Th2-high, corticosteroid-responsive asthma
Q30434426Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis
Q41019883Epithelial-derived IL-33 promotes intestinal tumorigenesis in Apc Min/+ mice
Q41023088Evaluation of Anti-Inflammatory Activities of Qingre-Qushi Recipe (QRQS) against Atopic Dermatitis: Potential Mechanism of Inhibition of IL-33/ST2 Signal Transduction
Q36553112Evaluation of the circulating levels of IL-12 and IL-33 in patients with breast cancer: influences of the tumor stages and cytokine gene polymorphisms
Q89723039Exercise enhances skeletal muscle regeneration by promoting senescence in fibro-adipogenic progenitors
Q48120429Exogenous IL-33 Restores Dendritic Cell Activation and Maturation in Established Cancer.
Q33815955Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells
Q34577102Exposure to cigarette smoke impacts myeloid-derived regulatory cell function and exacerbates airway hyper-responsiveness
Q88602737Exposure to low-dose bisphenol A during the juvenile period of development disrupts the immune system and aggravates allergic airway inflammation in mice
Q59791529Expression and Function of IL-33/ST2 Axis in the Central Nervous System Under Normal and Diseased Conditions
Q40767311Expression and potential roles of IL-33/ST2 in the immune regulation during Clonorchis sinensis infection
Q34149191Expression of IL-33 and its epigenetic regulation in Multiple Sclerosis
Q41267861Extracellular IL-33 cytokine, but not endogenous nuclear IL-33, regulates protein expression in endothelial cells
Q37608553Factors associated with plasma IL-33 levels in patients with chronic obstructive pulmonary disease
Q94561587Filarial Coinfection Is Associated With Higher Bacterial Burdens and Altered Plasma Cytokine and Chemokine Responses in Tuberculous Lymphadenitis
Q38947692First-Breath-Induced Type 2 Pathways Shape the Lung Immune Environment
Q36054682Full-length IL-33 promotes inflammation but not Th2 response in vivo in an ST2-independent fashion
Q39446268Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytes
Q36294725GATA2 is a critical transactivator for the human IL1RL1/ST2 promoter in mast cells/basophils: opposing roles for GATA2 and GATA1 in human IL1RL1/ST2 gene expression
Q35563351Genetic deletion of IL-25 (IL-17E) confers resistance to dextran sulfate sodium-induced colitis in mice
Q33821919Genetic variant in IL33 is associated with susceptibility to rheumatoid arthritis
Q37883044Genetics of interleukin 1 receptor-like 1 in immune and inflammatory diseases
Q34793361Genome-Wide Gene Expression Profiling Revealed a Critical Role for GATA3 in the Maintenance of the Th2 Cell Identity
Q37833146Genome-wide association studies for discovery of genes involved in asthma
Q38195863Genome-wide association studies of atopic dermatitis
Q28943402Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population
Q60907478Glucocorticoid Receptor Binding Inhibits an Intronic Enhancer and is Disrupted by rs4742170 (T) Allele Associated with Specific Wheezing Phenotype in Early Childhood
Q28395763Glyphosate-rich air samples induce IL-33, TSLP and generate IL-13 dependent airway inflammation
Q38756562Gut mucosal DAMPs in IBD: from mechanisms to therapeutic implications
Q35832735HPV16 E7 expression in skin induces TSLP secretion, type 2 ILC infiltration and atopic dermatitis-like lesions.
Q38625040Human Th2 but not Th9 cells release IL-31 in a STAT6/NF-κB-dependent way.
Q37727601IFN-γ directly controls IL-33 protein level through a STAT1- and LMP2-dependent mechanism
Q49461527IL-1 family cytokines and soluble receptors in systemic lupus erythematosus
Q36304279IL-1 family cytokines trigger sterile inflammatory disease
Q36005876IL-1 family members in the pathogenesis and treatment of metabolic disease: Focus on adipose tissue inflammation and insulin resistance
Q39402916IL-25 in allergic inflammation.
Q44983410IL-33 Acts to Express Schaffer Collateral/CA1 LTP and Regulate Learning and Memory by Targeting MyD88.
Q64100365IL-33 Ameliorates the Development of MSU-Induced Inflammation Through Expanding MDSCs-Like Cells
Q38808935IL-33 Effect on Quantitative Changes of CD4+CD25highFOXP3+ Regulatory T Cells in Children with Type 1 Diabetes
Q84698017IL-33 Exacerbates Eosinophil-Mediated Airway Inflammation
Q41161239IL-33 Exacerbates Periodontal Disease through Induction of RANKL.
Q47351617IL-33 Expression in Chronic Rhinosinusitis with Nasal Polyps and Its Relationship with Clinical Severity
Q89659668IL-33 Inhibits TNF-α-Induced Osteoclastogenesis and Bone Resorption
Q34105719IL-33 Priming Enhances Peritoneal Macrophage Activity in Response to Candida albicans
Q64326859IL-33 Promotes the Development of Colorectal Cancer Through Inducing Tumor-Infiltrating ST2L Regulatory T Cells in Mice
Q27315329IL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline.
Q38005217IL-33 and HMGB1 alarmins: sensors of cellular death and their involvement in liver pathology
Q93060094IL-33 and MRGPRX2-Triggered Activation of Human Skin Mast Cells-Elimination of Receptor Expression on Chronic Exposure, but Reinforced Degranulation on Acute Priming
Q60812017IL-33 and ST2 in Atopic Dermatitis: Expression Profiles and Modulation by Triggering Factors
Q92277121IL-33 and its increased serum levels as an alarmin for imminent pulmonary complications in polytraumatized patients
Q46324957IL-33 attenuates EAE by suppressing IL-17 and IFN-γ production and inducing alternatively activated macrophages.
Q34606519IL-33 attenuates anoxia/reoxygenation-induced cardiomyocyte apoptosis by inhibition of PKCβ/JNK pathway
Q35665373IL-33 attenuates the development of experimental autoimmune uveitis.
Q50787510IL-33 circulating serum levels are increased in patients with non-segmental generalized vitiligo.
Q40265668IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population.
Q47718005IL-33 deficiency slows cancer growth but does not protect against cisplatin-induced AKI in mice with cancer
Q57053348IL-33 drives the antitumor effects of dendritic cells via the induction of Tc9 cells
Q35758456IL-33 exacerbates acute kidney injury
Q35402371IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival.
Q48449404IL-33 expression in the cerebral cortex following experimental subarachnoid hemorrhage in rats
Q58770481IL-33 facilitates proliferation of colorectal cancer dependent on COX2/PGE
Q36050546IL-33 family members and asthma - bridging innate and adaptive immune responses.
Q90013907IL-33 in Tumor Immunity: Nothing to Sneeze At
Q37417506IL-33 independently induces eosinophilic pericarditis and cardiac dilation: ST2 improves cardiac function
Q33963816IL-33 induces IL-9 production in human CD4+ T cells and basophils
Q36514301IL-33 induces a hyporesponsive phenotype in human and mouse mast cells.
Q46504021IL-33 inhibits the differentiation and immunosuppressive activity of granulocytic myeloid-derived suppressor cells in tumor-bearing mice
Q34276672IL-33 is a crucial amplifier of innate rather than acquired immunity
Q34289318IL-33 is an unconventional Alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells
Q33740028IL-33 is negatively associated with the BMI and confers a protective lipid/metabolic profile in non-diabetic but not diabetic subjects.
Q24633495IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G
Q42935119IL-33 markedly activates murine eosinophils by an NF-κB-dependent mechanism differentially dependent upon an IL-4-driven autoinflammatory loop.
Q55405080IL-33 notably inhibits the growth of colon cancer cells.
Q39439468IL-33 polymorphisms are associated with increased risk of hay fever and reduced regulatory T cells in a birth cohort
Q36082314IL-33 promotes MHC class II expression in murine mast cells
Q38775054IL-33 promotes growth and liver metastasis of colorectal cancer in mice by remodeling the tumor microenvironment and inducing angiogenesis
Q41842923IL-33 released by alum is responsible for early cytokine production and has adjuvant properties
Q36040193IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms
Q26700067IL-33 signaling is essential to attenuate viral-induced encephalitis development by downregulating iNOS expression in the central nervous system
Q59808873IL-33 suppresses GSK-3β activation through an ST2-independent MyD88/TRAF6/RIP/PI3K/Akt pathway
Q41965694IL-33 synergizes with TCR and IL-12 signaling to promote the effector function of CD8+ T cells
Q33830896IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice.
Q35946057IL-33-Dependent Endothelial Activation Contributes to Apoptosis and Renal Injury in Orientia tsutsugamushi-Infected Mice
Q36793403IL-33-dependent induction of allergic lung inflammation by FcγRIII signaling.
Q36593464IL-33-induced alterations in murine intestinal function and cytokine responses are MyD88, STAT6, and IL-13 dependent
Q35557167IL-33-mediated protection against experimental cerebral malaria is linked to induction of type 2 innate lymphoid cells, M2 macrophages and regulatory T cells
Q33738493IL-33-responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polyps
Q37990785IL-33/ST2 axis in inflammation and immunopathology.
Q42204336IL-33/ST2 axis in innate and acquired immunity to tumors.
Q33925929IL-33/ST2 axis promotes mast cell survival via BCLXL.
Q35058035IL-33/ST2 correlates with severity of haemorrhagic fever with renal syndrome and regulates the inflammatory response in Hantaan virus-infected endothelial cells
Q39529075IL-33/ST2 involves the immunopathology of ocular toxoplasmosis in murine model
Q33779103IL-33/ST2-mediated inflammation in macrophages is directly abrogated by IL-10 during rheumatoid arthritis.
Q88723199IL-33/s-ST2 ratio, systemic symptoms, and basophil activation in Pru p 3-sensitized allergic patients
Q36960477IL-33: a novel danger signal system in atopic dermatitis
Q40305455IL33 and IL1RL1 variants are associated with asthma and atopy in a Brazilian population
Q38828462IL33 in rheumatoid arthritis: potencial contribution to pathogenesis
Q35142807Identification of an IFN-γ/mast cell axis in a mouse model of chronic asthma
Q35565839Identification of potential small molecule allosteric modulator sites on IL-1R1 ectodomain using accelerated conformational sampling method
Q44056900IgE and IL-33-mediated triggering of human basophils inhibits TLR4-induced monocyte activation.
Q36125752Immune markers and differential signaling networks in ulcerative colitis and Crohn's disease
Q38181015Immunobiology of critical pediatric asthma
Q91892681Immunomodulatory role of Interleukin-33 in large vessel vasculitis
Q38085051Immunopathogenesis of allergic disorders: current concepts
Q37982064Immunopathological roles of cytokines, chemokines, signaling molecules, and pattern-recognition receptors in systemic lupus erythematosus
Q36807908Implications for Interleukin-33 in solid organ transplantation
Q60046874Increased Expression of sST2 in Early HIV Infected Patients Attenuated the IL-33 Induced T Cell Responses
Q38830215Increased expression of deleted in malignant brain tumors (DMBT1) gene in precancerous gastric lesions: Findings from human and animal studies.
Q41958860Increased interleukin 33 in patients with neuro-Behcet's disease: correlation with MCP-1 and IP-10 chemokines
Q38159446Indication of immune activation in patients with perceived food hypersensitivity
Q37641240Induced interleukin-33 expression enhances the tumorigenic activity of rat glioma cells
Q34299338Inflammasomes in neuroinflammation and changes in brain function: a focused review
Q34358060Inflammatory bowel disease-associated interleukin-33 is preferentially expressed in ulceration-associated myofibroblasts.
Q34549969Inflammatory mechanisms in tendinopathy - towards translation
Q38627886Influence of IL-6, IL-33, and TNF-α on human mast cell activation: Lessons from single cell analysis by flow cytometry
Q28396866Inhalation of rod-like carbon nanotubes causes unconventional allergic airway inflammation
Q50087583Injury, repair, inflammation and metaplasia in the stomach.
Q38007827Innate and adaptive immune responses in asthma
Q39402938Innate and adaptive type 2 immunity in lung allergic inflammation.
Q36074379Innate immunological function of TH2 cells in vivo.
Q36908615Innate lymphoid cells in the initiation, regulation and resolution of inflammation
Q38325566Innate lymphoid cells involve in tumorigenesis.
Q35634065Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity.
Q45365691Innate type 2 immunity is associated with eosinophilic pleural effusion in primary spontaneous pneumothorax
Q55275991Integrated Expression Profiles Analysis Reveals Correlations Between the IL-33/ST2 Axis and CD8+ T Cells, Regulatory T Cells, and Myeloid-Derived Suppressor Cells in Soft Tissue Sarcoma.
Q41499755Intelectin contributes to allergen-induced IL-25, IL-33, and TSLP expression and type 2 response in asthma and atopic dermatitis
Q50320993Interleukin 33 and interleukin 4 regulate interleukin 31 gene expression and secretion from human laboratory of allergic diseases 2 mast cells stimulated by substance P and/or immunoglobulin E.
Q38702558Interleukin 33 is a guardian of barriers and a local alarmin
Q33987547Interleukin 33: a switch-hitting cytokine
Q55340253Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis.
Q38443719Interleukin-32γ suppresses allergic airway inflammation in mouse models of asthma
Q91656184Interleukin-33 (IL-33) Increases Hyperoxia-Induced Bronchopulmonary Dysplasia in Newborn Mice by Regulation of Inflammatory Mediators
Q60046076Interleukin-33 Contributes Toward Loss of Tolerance by Promoting B-Cell-Activating Factor of the Tumor-Necrosis-Factor Family (BAFF)-Dependent Autoantibody Production
Q40889691Interleukin-33 Expression Indicates a Favorable Prognosis in Malignant Salivary Gland Tumors
Q54967737Interleukin-33 Receptor (ST2) Deficiency Improves the Outcome of Staphylococcus aureus-Induced Septic Arthritis.
Q36228512Interleukin-33 and RANK-L Interplay in the Alveolar Bone Loss Associated to Periodontitis
Q59351894Interleukin-33 and ST2 Signaling in Tumor Microenvironment
Q38859663Interleukin-33 and its Receptor in Pulmonary Inflammatory Diseases
Q42181941Interleukin-33 drives activation of alveolar macrophages and airway inflammation in a mouse model of acute exacerbation of chronic asthma
Q46419763Interleukin-33 drives hepatic fibrosis through activation of hepatic stellate cells
Q52678075Interleukin-33 enhanced the migration and invasiveness of human lung cancer cells.
Q36751804Interleukin-33 enhances programmed oncosis of ST2L-positive low-metastatic cells in the tumour microenvironment of lung cancer.
Q51071343Interleukin-33 exacerbates acute colitis via interleukin-4 in mice.
Q59333251Interleukin-33 in Systemic Sclerosis: Expression and Pathogenesis
Q36585708Interleukin-33 in the human placenta
Q38753216Interleukin-33 in tumorigenesis, tumor immune evasion, and cancer immunotherapy
Q35105619Interleukin-33 increases antibacterial defense by activation of inducible nitric oxide synthase in skin
Q47377251Interleukin-33 modulates the expression of human β-defensin 2 in human primary keratinocytes and may influence the susceptibility to bacterial superinfection in acute atopic dermatitis
Q37596499Interleukin-33 potentiates bleomycin-induced lung injury
Q34448122Interleukin-33 primes mast cells for activation by IgG immune complexes
Q50515474Interleukin-33 prolongs allograft survival during chronic cardiac rejection.
Q40972417Interleukin-33 promotes Th2 immune responses in infected mice with Schistosoma japonicum
Q64104235Interleukin-33 regulates hematopoietic stem cell regeneration after radiation injury
Q33678403Interleukin-33 regulates intestinal inflammation by modulating macrophages in inflammatory bowel disease
Q39324207Interleukin-33 regulates tissue remodelling and inhibits angiogenesis in the eye.
Q39209203Interleukin-33 requires CMRF35-like molecule-1 expression for induction of myeloid cell activation
Q64132725Interleukin-33 safeguards neutrophils in sepsis
Q45317118Interleukin-33 signaling
Q35785935Interleukin-33 upregulation in peripheral leukocytes and CNS of multiple sclerosis patients.
Q41945735Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis
Q39084378Interleukin-33/ST2 axis promotes breast cancer growth and metastases by facilitating intratumoral accumulation of immunosuppressive and innate lymphoid cells
Q89481704Interleukin-33: Its Emerging Role in Allergic Diseases
Q91640755International expert consensus on the management of allergic rhinitis (AR) aggravated by air pollutants: Impact of air pollution on patients with AR: Current knowledge and future strategies
Q38417709Intratumorally Establishing Type 2 Innate Lymphoid Cells Blocks Tumor Growth.
Q28397819Intravenously delivered graphene nanosheets and multiwalled carbon nanotubes induce site-specific Th2 inflammatory responses via the IL-33/ST2 axis
Q48272507Investigating the role of IL-33 in the pathogenesis of Behçet's Disease
Q39032113Involvement of ERK and p38 MAPK pathways on Interleukin-33-induced RANKL expression in osteoblastic cells
Q39455563Lactic Acid Suppresses IL-33-Mediated Mast Cell Inflammatory Responses via Hypoxia-Inducible Factor-1α-Dependent miR-155 Suppression.
Q41437208Lineage(-)Sca1+c-Kit(-)CD25+ cells are IL-33-responsive type 2 innate cells in the mouse bone marrow
Q37123845Long-term IL-33-producing epithelial progenitor cells in chronic obstructive lung disease.
Q60301285Longitudinal changes in the expression of IL-33 and IL-33 regulated genes in relapsing remitting MS
Q85224339Loss of Suppression of Tumorigenicity 2 (ST2) Gene Reverses Sepsis-induced Inhibition of Lung Host Defense in Mice
Q51491152Low-dose benzo[a]pyrene aggravates allergic airway inflammation in mice.
Q36991150Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production
Q54314108Lysosome biogenesis regulated by the amino-acid transporter SLC15A4 is critical for functional integrity of mast cells.
Q37609295M2 macrophages or IL-33 treatment attenuate ongoing Mycobacterium tuberculosis infection.
Q34639723Macrophages as IL-25/IL-33-responsive cells play an important role in the induction of type 2 immunity
Q38008374Mast Cells Respond to Cell Injury through the Recognition of IL-33.
Q26824984Mast cell activation: a complex interplay of positive and negative signaling pathways
Q35077675Mast cell mediator responses and their suppression by pathogenic and commensal microorganisms
Q84742904Mast cells
Q35211917Measurement of interleukin-33 (IL-33) and IL-33 receptors (sST2 and ST2L) in patients with rheumatoid arthritis
Q59271653Mechanisms of allergen-specific immunotherapy
Q33797551Mechanisms of smooth muscle responses to inflammation
Q37509047Mechanisms of tolerance and allergic sensitization in the airways and the lungs.
Q85544032Membrane microdomain organization, calcium signal, and NFAT activation as an important axis in polarized Th cell function
Q28260209MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease
Q58316591Molecular Definition of Inflammasomes
Q35988587Molecular adjuvant IL-33 enhances the potency of a DNA vaccine in a lethal challenge model
Q28391783Multi-walled carbon nanotube instillation impairs pulmonary function in C57BL/6 mice
Q37617670Murine mast cells secrete and respond to interleukin-33
Q35880106Mutated major histocompatibility complex class II transactivator up-regulates interleukin-33-dependent differentiation of Th2 subset through Nod2 binding for NLR (NOD-like receptor) signaling initiation
Q92072341Negative Association of Interleukin-33 Plasma Levels and Schistosomiasis Infection in a Site of Polyparasitism in Rural Cameroon
Q47893052Neuroinflammation, Mast Cells, and Glia: Dangerous Liaisons
Q37345931Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice
Q57289127New Cytokines in the Pathogenesis of Atopic Dermatitis-New Therapeutic Targets
Q37847502New insights into the role of mast cells in autoimmunity: evidence for a common mechanism of action?
Q64883707Novel Biomarkers in Heart Failure Beyond Natriuretic Peptides - The Case for Soluble ST2.
Q35191071Novel cytokine signaling pathways in inflammatory bowel disease: insight into the dichotomous functions of IL-33 during chronic intestinal inflammation
Q38033164Novel identified receptors on mast cells
Q38056157Novel insights into mechanisms of food allergy and allergic airway inflammation using experimental mouse models
Q38038253Ocular manifestations of the autoinflammatory syndromes
Q91811754Oncostatin M in the Regulation of Connective Tissue Cells and Macrophages in Pulmonary Disease
Q91587353Oral exposure to low dose bisphenol A aggravates allergic airway inflammation in mice
Q42937988Osteoblast Hypoxia-Inducible Factor-1α Pathway Activation Restrains Osteoclastogenesis via the Interleukin-33-MicroRNA-34a-Notch1 Pathway
Q52141871Overexpression of interleukin-33 is associated with poor prognosis of patients with glioma.
Q28505577Paracrine IL-33 stimulation enhances lipopolysaccharide-mediated macrophage activation
Q54433261Patch testing of food allergens promotes Th17 and Th2 responses with increased IL-33: a pilot study.
Q34994590Pathogenic mouse hepatitis virus or poly(I:C) induce IL-33 in hepatocytes in murine models of hepatitis
Q34073302Pathophysiology of cisplatin-induced acute kidney injury
Q37117633Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD.
Q36082339Peripheral basophil reactivity, CD203c expression by Cryj1 stimulation, is useful for diagnosing seasonal allergic rhinitis by Japanese cedar pollen
Q98730943Peripheral levels of sST2 are increased in patients with temporal lobe epilepsy: Additional evidence of low-grade inflammation
Q90398115Pilot-Scale Study Of Human Plasma Proteomics Identifies ApoE And IL33 As Markers In Atopic Asthma
Q38907279Plasma IL-33 in atopic patients correlates with pro-inflammatory cytokines and changes cholesterol transport protein expression: a surprising neutral overall impact on atherogenicity
Q87454549Plasma soluble ST2 levels correlate with disease severity and predict clinical worsening in patients with pulmonary arterial hypertension
Q35841095Polymorphisms of ST2-IL18R1-IL18RAP gene cluster: a new risk for autoimmune thyroid diseases.
Q37706803Positive selection of IL-33 in adaptive immunity of domestic Chinese goats.
Q36539857Potential effector and immunoregulatory functions of mast cells in mucosal immunity
Q54960727Potential role of the IL-33/ST2 axis in celiac disease.
Q48319320Potentiating Tissue-Resident Type 2 Innate Lymphoid Cells by IL-33 to Prevent Renal Ischemia-Reperfusion Injury.
Q47387189Predictive value of serum sST2 in preschool wheezers for development of asthma with high FeNO.
Q39406925Profibrotic interleukin-33 is correlated with uterine leiomyoma tumour burden
Q47101543Prognostic role of soluble suppression of tumorigenicity-2 on cardiovascular mortality in outpatients with heart failure
Q47992175Proinflammatory and regulatory cytokines and chemokines in infants with uncomplicated and severe Plasmodium falciparum malaria
Q37730806Prolonged activation of IL-5-producing ILC2 causes pulmonary arterial hypertrophy
Q38793189Protection against oxidative stress by vitamin D in cone cells
Q41331530Protocadherin-1 binds to SMAD3 and suppresses TGF-β1-induced gene transcription
Q38040602Recent developments in basophil research: do basophils initiate and perpetuate type 2 T-helper cell responses?.
Q42607304Reduced IL-33 plasma levels in aplastic anemia
Q54535403Reduction in IL-33 expression exaggerates ischaemia/reperfusion-induced myocardial injury in mice with diabetes mellitus.
Q38742473Regulation of IL-33 by Oncostatin M in Mouse Lung Epithelial Cells.
Q36056528Regulation of innate CD8+ T-cell activation mediated by cytokines
Q36092456Regulation of mast cell responses in health and disease
Q26752524Regulatory Role of IL-1R8 in Immunity and Disease
Q38003474Regulatory cells in allergen-specific immunotherapy
Q35810246Respiratory Syncytial Virus Disease Is Mediated by Age-Variable IL-33.
Q37829145Respiratory and gastrointestinal epithelial modulation of the immune response during viral infection.
Q41145879Rhinovirus infection interferes with induction of tolerance to aeroantigens through OX40 ligand, thymic stromal lymphopoietin, and IL-33.
Q39017773Role of Anti-inflammatory Cytokines IL-35 and IL-37 in Asthma
Q37126011Role of IL-33 and ST2 signalling pathway in multiple sclerosis: expression by oligodendrocytes and inhibition of myelination in central nervous system.
Q38195380Role of interleukin 33 in respiratory allergy and asthma.
Q37620811Role of the IL-33-ST2 axis in sepsis
Q64102858Role of the IL-33/ST2/p38 signaling pathway in the immune response of corneal epithelial cells to infection
Q26747318Roles of IL-33 in Resistance and Tolerance to Systemic Candida albicans Infections
Q28740320ST2 and IL-33 in pregnancy and pre-eclampsia
Q37101727ST2 deletion enhances innate and acquired immunity to murine mammary carcinoma
Q36028908ST2L Transmembrane Receptor Expression: An Immunochemical Study on Endarterectomy Samples
Q35075328Semaphorin 3A controls allergic and inflammatory responses in experimental allergic conjunctivitis
Q33901176Serine protease inhibition attenuates rIL-12-induced GZMA activity and proinflammatory events by modulating the Th2 profile from estrogen-treated mice.
Q37284292Serum IL-33 Is a Novel Diagnostic and Prognostic Biomarker in Acute Ischemic Stroke
Q36004251Serum IL-33 levels are associated with liver damage in patients with chronic hepatitis B
Q35725505Serum IL-33 levels are associated with liver damage in patients with chronic hepatitis C
Q37498738Serum IL-33, a new marker predicting response to rituximab in rheumatoid arthritis
Q37430618Serum Levels of Soluble ST2 and IL-10 Are Associated with Disease Severity in Patients with IgA Nephropathy
Q28239055Serum amyloid A induces interleukin-33 expression through an IRF7-dependent pathway
Q35122488Serum soluble ST2 is associated with ER-positive breast cancer
Q53154978Severe obesity increases adipose tissue expression of interleukin-33 and its receptor ST2, both predominantly detectable in endothelial cells of human adipose tissue.
Q36240848Signal transduction and chemotaxis in mast cells
Q37700227Significance of interleukin-33 and its related cytokines in patients with breast cancers
Q37439634Soluble IL-33 receptor sST2 inhibits colorectal cancer malignant growth by modifying the tumour microenvironment
Q37229321Soluble ST2 and Galectin-3: What We Know and Don't Know Analytically
Q45870185Soluble ST2 is not independently associated with androgen and estrogen status in healthy males and females
Q36144350Sterile inflammation - do innate lymphoid cell subsets play a role?
Q48009734Stromal cell cadherin-11 regulates adipose tissue inflammation and diabetes.
Q27679811Structural insights into the interaction of IL-33 with its receptors
Q57049900Substance P and IL-33 administered together stimulate a marked secretion of IL-1β from human mast cells, inhibited by methoxyluteolin
Q84930428Successfully mapping novel asthma loci by GWAS
Q42375854TCR-independent functions of Th17 cells mediated by the synergistic actions of cytokines of the IL-12 and IL-1 families.
Q35972372TLR3 Agonist Poly-IC Induces IL-33 and Promotes Myelin Repair
Q47596055Targeting IL-33/ST2 signaling: regulation of immune function and analgesia
Q38057796Th2 cytokine antagonists: potential treatments for severe asthma
Q89482967The Confounding Effects of Non-cardiac Pathologies on the Interpretation of Cardiac Biomarkers
Q36324815The Deubiquitinase USP17 Regulates the Stability and Nuclear Function of IL-33.
Q89551931The Diabetic Cardiac Fibroblast: Mechanisms Underlying Phenotype and Function
Q35665034The Effects of Antigen-Specific IgG1 Antibody for the Pulmonary-Hypertension-Phenotype and B Cells for Inflammation in Mice Exposed to Antigen and Fine Particles from Air Pollution
Q41961424The GOLD domain-containing protein TMED1 is involved in interleukin-33 signaling.
Q37217084The IL-33-ST2L pathway is associated with coronary artery disease in a Chinese Han population
Q94503619The IL-33/ST2 Axis in Immune Responses Against Parasitic Disease: Potential Therapeutic Applications
Q35607302The IL-33/ST2 axis augments effector T-cell responses during acute GVHD.
Q37174541The IL-33/ST2 axis is associated with human visceral leishmaniasis and suppresses Th1 responses in the livers of BALB/c mice infected with Leishmania donovani
Q36597522The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice
Q41948431The Other T Helper Cells in Asthma Pathogenesis
Q59138410The Risk G Allele of the Single-Nucleotide Polymorphism rs928413 Creates a CREB1-Binding Site That Activates Promoter in Lung Epithelial Cells
Q51308719The Role of IL-33 on LPS-Induced Acute Lung Injury in Mice.
Q37571181The Role of IL-33-Dependent Inflammation in the Tumor Microenvironment.
Q58756972The Role of IL-33/ST2 Pathway in Tumorigenesis
Q33593742The ST2/IL-33 Axis in Immune Cells during Inflammatory Diseases
Q38131032The alarmin functions of high-mobility group box-1 and IL-33 in the pathogenesis of systemic lupus erythematosus.
Q34708854The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses
Q38967737The epithelial barrier and immunoglobulin A system in allergy
Q38071241The evolutionary role of the IL-33/ST2 system in host immune defence
Q47414882The full-length interleukin-33 (FLIL33)-importin-5 interaction does not regulate nuclear localization of FLIL33 but controls its intracellular degradation.
Q34391415The interleukin-1 family: back to the future
Q37766451The many paths to asthma: phenotype shaped by innate and adaptive immunity
Q34590317The novel cytokine interleukin-33 activates acinar cell proinflammatory pathways and induces acute pancreatic inflammation in mice
Q38424483The potential role of IL-33/ST2 signaling in fibrotic diseases
Q54330061The role of IL-33 and its receptor ST2 in human nasal epithelium with allergic rhinitis.
Q26783420The role of IL-33 and mast cells in allergy and inflammation
Q46317388The variations in the IL1RL1 gene and susceptibility to preeclampsia
Q40942192Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation
Q30418533Transcriptional regulation of murine IL-33 by TLR and non-TLR agonists
Q53126993Tumor necrosis factor-α regulates interleukin-33 expression through extracellular signal-regulated kinase, p38, and nuclear factor-κB pathways in airway epithelial cells.
Q34749359Tumoral expression of IL-33 inhibits tumor growth and modifies the tumor microenvironment through CD8+ T and NK cells
Q47285918Tuning inflammation and immunity by the negative regulators IL-1R2 and IL-1R8.
Q58104422Type 2 Innate Lymphoid Cells Impede IL-33-Mediated Tumor Suppression
Q38064849Type 2 innate lymphoid cells: friends or foes-role in airway allergic inflammation and asthma
Q27004109Understanding the role of antibodies in murine infections with Heligmosomoides (polygyrus) bakeri: 35 years ago, now and 35 years ahead
Q33855694Unique temporal and spatial expression patterns of IL-33 in ovaries during ovulation and estrous cycle are associated with ovarian tissue homeostasis
Q38755493Vascularized composite allograft-specific characteristics of immune responses
Q92874729Vitamin D Attenuates Oxidative Damage and Inflammation in Retinal Pigment Epithelial Cells
Q43173595Vitamin D enhances production of soluble ST2, inhibiting the action of IL-33.
Q37842638What can the periodontal community learn from the pathophysiology of rheumatoid arthritis?
Q37798030What's new in asthma pathophysiology and immunopathology?
Q41612970miR-487b mitigates chronic heart failure through inhibition of the IL-33/ST2 signaling pathway
Q89900327p38 MAPK signalling regulates cytokine production in IL-33 stimulated Type 2 Innate Lymphoid cells

Search more.