Calcium/calmodulin-dependent protein kinases as potential targets in cancer therapy.

scientific article

Calcium/calmodulin-dependent protein kinases as potential targets in cancer therapy. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1517/14728222.9.4.791
P698PubMed publication ID16083343

P50authorJames A. McCubreyQ42317570
Richard A. FranklinQ68547480
Christopher J HoweQ70203152
Oswaldo G Rodriguez-MoraQ114723352
Michelle M LaHairQ114723353
P2860cites workDeath-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosisQ22011046
Extracellular signal-regulated kinase mediates phosphorylation of tropomyosin-1 to promote cytoskeleton remodeling in response to oxidative stress: impact on membrane blebbingQ24299646
Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase BQ24309564
Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascadeQ24312887
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Ca2+/calmodulin-dependent protein kinase II: localization in the interphase nucleus and the mitotic apparatus of mammalian cellsQ24557611
Physical and functional interaction of androgen receptor with calmodulin in prostate cancer cellsQ24598075
Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinaseQ24613134
Structural features of Ca2+/calmodulin-dependent protein kinase II revealed by electron microscopyQ24642469
The linkage between beta1 integrin and the actin cytoskeleton is differentially regulated by tyrosine and serine/threonine phosphorylation of beta1 integrin in normal and cancerous human breast cellsQ24794852
Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase BQ28116107
Checkpoints: controls that ensure the order of cell cycle eventsQ28131705
Ca(2+)/CaM-dependent kinases: from activation to functionQ28206372
Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cellsQ28215810
Cyclin-dependent kinases: engines, clocks, and microprocessorsQ29614786
Mitogen-activated protein kinase pathwaysQ29618431
Cancer statistics, 2004Q29620739
Primary brain tumours in adults.Q30765293
NF-kappaB activation by N-CAM and cytokines in astrocytes is regulated by multiple protein kinases and redox modulationQ31911355
The Ca-calmodulin-dependent protein kinase cascadeQ33656500
Signal transduction and cellular radiation responsesQ33835066
The Rb/E2F pathway: expanding roles and emerging paradigmsQ34052659
Signaling pathways in cell death and survival after photodynamic therapyQ34095520
DAP kinase-a proapoptotic gene that functions as a tumor suppressorQ34174358
Reactive oxygen-dependent production of novel photochemotherapeutic agentsQ34190140
DAP-kinase: from functional gene cloning to establishment of its role in apoptosis and cancerQ34225868
NF-kappa B signaling pathway as a target for human tumor radiosensitizationQ34418332
3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitroQ34452063
Structure and regulation of calcium/calmodulin-dependent protein kinasesQ34466004
Death associated protein kinase: from regulation of apoptosis to tumor suppressive functions and B cell malignanciesQ34629161
Structure and enzymology of a death-associated protein kinaseQ34740887
Antioxidant nutrients and adriamycin toxicity.Q34904589
Cyclin D1 and Molecular Chaperones: Implications for TumorigenesisQ35540960
Regulation of cell cycle progression by calcium/calmodulin-dependent pathwaysQ35606161
The good, the bad and the ugly: the practical consequences of centrosome amplificationQ35705371
DAP-kinase as a target for drug design in cancer and diseases associated with accelerated cell deathQ35818579
Redox regulation of NF-kappaB activation: distinct redox regulation between the cytoplasm and the nucleusQ36038167
Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: selective regulation of mitogen-activated protein kinase activation and fas ligand expressionQ36376476
Activity and regulation by growth factors of calmodulin-dependent protein kinase III (elongation factor 2-kinase) in human breast cancerQ36617301
Human T-cell leukemia virus type I tax protein induces the expression of anti-apoptotic gene Bcl-xL in human T-cells through nuclear factor-kappaB and c-AMP responsive element binding protein pathwaysQ39269100
Calcium/calmodulin-dependent kinase I and calcium/calmodulin-dependent kinase kinase participate in the control of cell cycle progression in MCF-7 human breast cancer cells.Q40408904
The transcriptional activity of estrogen receptor-alpha is dependent on Ca2+/calmodulin.Q40469627
Oxidative stress attenuates Fas-mediated apoptosis in Jurkat T cell line through Bfl-1 induction.Q40481699
Regulation of cyclin D1/Cdk4 complexes by calcium/calmodulin-dependent protein kinase I.Q40593826
Calcium-induced ERK activation in human T lymphocytes occurs via p56(Lck) and CaM-kinase.Q40829299
Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathwayQ40986827
Calmodulin is essential for estrogen receptor interaction with its motif and activation of responsive promoterQ40990801
Activation of Ca2+/calmodulin-dependent protein kinase (CaM-kinase) IV by CaM-kinase kinase in Jurkat T lymphocytesQ41258093
p21 as a Common Signaling Target of Reactive Free Radicals and Cellular Redox StressQ41296576
Transducing signals of life and deathQ41382894
Dual role of calmodulin in autophosphorylation of multifunctional CaM kinase may underlie decoding of calcium signalsQ41469189
Functional implications of the subunit composition of neuronal CaM kinase II.Q41682758
Mechanism of activation and function of protein kinase B.Q41732739
DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activityQ41848995
CaMK-II inhibition reduces cyclin D1 levels and enhances the association of p27kip1 with Cdk2 to cause G1 arrest in NIH 3T3 cellsQ42830091
Participation of the calcium/calmodulin-dependent kinases in hydrogen peroxide-induced Ikappa B phosphorylation in human T lymphocytesQ43735841
Group I metabotropic glutamate receptors control phosphorylation of CREB, Elk-1 and ERK via a CaMKII-dependent pathway in rat striatumQ43780977
Calcium, calmodulin, and CaMKII requirement for initiation of centrosome duplication in Xenopus egg extractsQ43859355
Functional significance of activation of calcium/calmodulin-dependent protein kinase II in angiotensin II--induced vascular hyperplasia and hypertensionQ43908306
The spin trapping agent PBN stimulates H2 O2 -induced Erk and Src kinase activity in human neuroblastoma cellsQ44024928
Calcium/calmodulin-dependent protein kinase II regulation of c-FLIP expression and phosphorylation in modulation of Fas-mediated signaling in malignant glioma cellsQ44259011
CyclinB1 expression is elevated and mitosis is delayed in HeLa cells expressing autonomous CaMKIIQ44589911
PKC-delta and CaMKII-delta 2 mediate ATP-dependent activation of ERK1/2 in vascular smooth muscleQ44746409
Redox regulation of the calcium/calmodulin-dependent protein kinases.Q45007516
H2O2-induced transactivation of EGF receptor requires Src and mediates ERK1/2, but not Akt, activation in renal cellsQ47790130
Neurite outgrowth of neuroblastoma cells overexpressing alpha and beta isoforms of Ca2+/calmodulin-dependent protein kinase II-effects of protein kinase inhibitorsQ47962155
A signaling complex of Ca2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A.Q48445015
The role of PI 3-kinase in insulin actionQ58438150
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)791-808
P577publication date2005-08-01
P1433published inExpert Opinion on Therapeutic TargetsQ5421214
P1476titleCalcium/calmodulin-dependent protein kinases as potential targets in cancer therapy
P478volume9

Reverse relations

cites work (P2860)
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Q37164501Specific detection of CD56 (NCAM) isoforms for the identification of aggressive malignant neoplasms with progressive development
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Q39638171Targeting the cancer initiating cell: The Achilles’ heel of cancer

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