MTRR silencing inhibits growth and cisplatin resistance of ovarian carcinoma via inducing apoptosis and reducing autophagy

scientific article

MTRR silencing inhibits growth and cisplatin resistance of ovarian carcinoma via inducing apoptosis and reducing autophagy is …
instance of (P31):
scholarly articleQ13442814

External links are
P932PMC publication ID4626414
P698PubMed publication ID26550452

P2093author name stringLi Li
Qi Wang
Jia Chen
Wei Zhang
Fu-Qiang Yin
Lin-Hai Yan
P2860cites workEsophageal and gastric cardia cancer risk and folate- and vitamin B(12)-related polymorphisms in Linxian, ChinaQ23923302
Maintenance chemotherapy for ovarian cancerQ24201758
Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuriaQ24317481
Cre-lox-regulated conditional RNA interference from transgenesQ24564248
AKT/PKB signaling: navigating downstreamQ24657857
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cellsQ24672969
Cancer statistics, 2013Q27860762
A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifidaQ28141956
Differences in the efficiency of reductive activation of methionine synthase and exogenous electron acceptors between the common polymorphic variants of human methionine synthase reductaseQ28213355
The epigenomics of cancerQ28289975
Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membraneQ28647586
Targeting multidrug resistance in cancerQ29616803
Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8Q29620200
Inherited determinants of ovarian cancer survivalQ33638923
Relationship between dietary and supplemental intake of folate, methionine, vitamin B6 and folate receptor alpha expression in ovarian tumorsQ33765535
A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancerQ34091420
Long-term cisplatin exposure impairs autophagy and causes cisplatin resistance in human lung cancer cellsQ34141265
Evolution of decitabine development: accomplishments, ongoing investigations, and future strategiesQ34768789
Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: possible involvement of the phosphoinositide-3 kinase/Akt pathway.Q34866669
CpG-island methylation and epigenetic control of resistance to chemotherapy.Q35928398
Folate intake and methylenetetrahydrofolate reductase gene polymorphisms as predictive and prognostic biomarkers for ovarian cancer riskQ35933841
Role of mitochondria as the gardens of cell deathQ36263117
Genetic variants in the folate pathway and risk of childhood acute lymphoblastic leukemiaQ37096589
Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinomaQ37428076
Genetic variation in the one-carbon transfer pathway and ovarian cancer riskQ37450640
Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistanceQ37478653
Autophagy and ionizing radiation in tumors: the "survive or not survive" dilemmaQ38010124
Autophagy suppresses melanoma tumorigenesis by inducing senescenceQ39050017
Overexpression of EZH2 contributes to acquired cisplatin resistance in ovarian cancer cells in vitro and in vivoQ39671100
Azacitidine enhances sensitivity of platinum-resistant ovarian cancer cells to carboplatin through induction of apoptosisQ39901280
Epigenetic silencing of HSulf-1 in ovarian cancer:implications in chemoresistance.Q40169144
Dominant-negative histone H3 lysine 27 mutant derepresses silenced tumor suppressor genes and reverses the drug-resistant phenotype in cancer cellsQ40272840
5-aza-2'-deoxycytidine upregulates caspase-9 expression cooperating with p53-induced apoptosis in human lung cancer cellsQ40531794
Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeuticsQ41933492
One-carbon metabolism-related gene polymorphisms and risk of breast cancerQ44933198
Establishment of 5 resistant ovarian cancer cell strains and expression of resistance-related genesQ45019004
Alcohol drinking and one-carbon metabolism-related gene polymorphisms on pancreatic cancer riskQ46325252
Polymorphisms of methionine synthase and methionine synthase reductase and risk of squamous cell carcinoma of the head and neck: a case-control analysisQ46491223
Functional polymorphisms in folate metabolism genes influence the risk of meningioma and gliomaQ46593237
Establishment and biological characteristics of a platinum-resistance nude mouse model in epithelial ovarian cancerQ50447436
Methionine synthase reductase A66G polymorphism contributes to tumor susceptibility: evidence from 35 case-control studies.Q53287202
One-carbon metabolism-related gene polymorphisms and risk of head and neck squamous cell carcinoma: case-control study.Q53544221
Folate metabolic gene polymorphisms and childhood acute lymphoblastic leukemia: a case-control study.Q53585636
Methylenetetrahydrofolate reductase gene polymorphisms as predictive and prognostic biomarkers in ovarian cancer risk.Q54313546
Methionine Synthase Reductase Gene A66G Polymorphism is Associated with Risk of Colorectal CancerQ55036516
Impact of one-carbon metabolism-related gene polymorphisms on risk of lung cancer in Japan: a case–control studyQ57918718
Folic acid supplementation, MTHFR and MTRR polymorphisms, and the risk of childhood leukemia: the ESCALE study (SFCE)Q58317417
A66G and C524T polymorphisms of the methionine synthase reductase gene are associated with congenital heart defects in the Chinese Han populationQ82372468
Interactions of 5'-UTR Thymidylate Synthase Polymorphism with 677C→ T Methylene Tetrahydrofolate Reductase and 66A→ G Methyltetrahydrofolate Homocysteine Methyl-transferase Reductase Polymorphisms Determine Susceptibility to Coronary Artery DiseaseQ85230620
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectautophagyQ288322
cisplatinQ412415
ovarian carcinomaQ18556145
P304page(s)1510-1527
P577publication date2015-09-15
P1433published inAmerican Journal of Translational ResearchQ4744272
P1476titleMTRR silencing inhibits growth and cisplatin resistance of ovarian carcinoma via inducing apoptosis and reducing autophagy
P478volume7

Reverse relations

cites work (P2860)
Q64098517Aberrant Expression of Folate Metabolism Enzymes and Its Diagnosis and Survival Prediction in Ovarian Carcinoma
Q37696331Autophagy as an emerging therapy target for ovarian carcinoma
Q38795910Autophagy regulates resistance of non-small cell lung cancer cells to paclitaxel
Q99604766B Vitamins and One-Carbon Metabolism: Implications in Human Health and Disease
Q36841375Colorectal cancer cells are resistant to anti-EGFR monoclonal antibody through adapted autophagy
Q92890176Deregulation of folate pathway gene expression correlates with poor prognosis in acute leukemia
Q64233753Differential effects of ginkgol C17:1 on cisplatin-induced cytotoxicity: Protecting human normal L02 hepatocytes versus sensitizing human hepatoma HepG2 cells
Q49335119Effects of ginkgol C17:1 on cisplatin-induced autophagy and apoptosis in HepG2 cells
Q39200379Insulin-like growth factor 1 antagonizes lumbar disc degeneration through enhanced autophagy
Q42293431Redox-Related Epigenetic Mechanisms in Glioblastoma: Nuclear Factor (Erythroid-Derived 2)-Like 2, Cobalamin, and Dopamine Receptor Subtype 4
Q47096017Role of HIF-1a in regulating autophagic cell survival during cerebral ischemia reperfusion in rats
Q37732938Tetrahydrocurcumin reduces oxidative stress-induced apoptosis via the mitochondrial apoptotic pathway by modulating autophagy in rats after traumatic brain injury

Search more.