Tetrahydrocurcumin reduces oxidative stress-induced apoptosis via the mitochondrial apoptotic pathway by modulating autophagy in rats after traumatic brain injury

scientific article published on 15 March 2017

Tetrahydrocurcumin reduces oxidative stress-induced apoptosis via the mitochondrial apoptotic pathway by modulating autophagy in rats after traumatic brain injury is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID5375984
P698PubMed publication ID28386319

P50authorMengliang ZhouQ80012989
P2093author name stringJie Li
Xiang Li
Xiao Han
Chao Tang
Liwen Li
Zhennan Ye
Shanting Gao
Yongyue Gao
Zihuan Zhang
Zong Zhuang
P2860cites workAnimal models of traumatic brain injuryQ27025091
Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in ratsQ28209989
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagyQ29614178
Autophagy in health and disease: a double-edged swordQ29618103
Highly stabilized curcumin nanoparticles tested in an in vitro blood-brain barrier model and in Alzheimer's disease Tg2576 miceQ30540417
Cerebral ischemia-hypoxia induces intravascular coagulation and autophagyQ33998182
Autophagy and its possible roles in nervous system diseases, damage and repairQ34552018
Mitochondrial mechanisms of cell death and neuroprotection in pediatric ischemic and traumatic brain injuryQ34988707
MTRR silencing inhibits growth and cisplatin resistance of ovarian carcinoma via inducing apoptosis and reducing autophagyQ36225822
Free radicals, mitochondria, and hypoxia-ischemia in the developing brainQ36380301
Inhibition of autophagy prevents hippocampal pyramidal neuron death after hypoxic-ischemic injuryQ36559658
Activation of the calcium-sensing receptor promotes apoptosis by modulating the JNK/p38 MAPK pathway in focal cerebral ischemia-reperfusion in miceQ36841281
Pharmacologic preconditioning with berberine attenuating ischemia-induced apoptosis and promoting autophagy in neuronQ36841380
microRNA-22 attenuates neuronal cell apoptosis in a cell model of traumatic brain injuryQ36879624
Mitochondrial membrane permeabilization in neuronal injuryQ37526353
Signal transduction to the permeability transition pore.Q37691823
Mitochondria: hub of injury responses in the developing brain.Q38181298
Tetrahydrocurcumin ameliorates homocysteinylated cytochrome-c mediated autophagy in hyperhomocysteinemia mice after cerebral ischemia.Q39343315
Crosstalk between apoptosis and autophagy within the Beclin 1 interactomeQ39352440
Traumatic Brain Injury-Induced Neuronal Apoptosis is Reduced Through Modulation of PI3K and Autophagy Pathways in Mouse by FTY720.Q40811091
What are the sources of hydrogen peroxide production by heart mitochondria?Q41393384
Autophagic proteolysis: control and specificityQ41498958
Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damageQ41930602
Autophagy regulates the processing of amino terminal huntingtin fragmentsQ45291371
Autophagy in hypoxia-ischemia induced brain injury: evidence and speculationsQ46231075
Argon mediates protection by interleukin-8 suppression via a TLR2/TLR4/STAT3/NF-κB pathway in a model of apoptosis in neuroblastoma cells in vitro and following ischemia-reperfusion injury in rat retina in vivoQ46550087
Luteolin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE pathwayQ46917468
Propofol administration improves neurological function associated with inhibition of pro-inflammatory cytokines in adult rats after traumatic brain injuryQ47444808
Alpha lipoic acid inhibits neural apoptosis via a mitochondrial pathway in rats following traumatic brain injury.Q48137853
Rapamycin protects against apoptotic neuronal death and improves neurologic function after traumatic brain injury in mice via modulation of the mTOR-p53-Bax axisQ48442051
Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2-ARE signaling pathway as a potential mechanismQ48785680
Protective effect of tetrahydrocurcumin against cisplatin-induced renal damage: in vitro and in vivo studies.Q53232943
Ultrastructural and immunocytochemical characterization of autophagic vacuoles in isolated hepatocytes: effects of vinblastine and asparagine on vacuole distributions.Q54157167
Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR and MAPK signaling pathways in human leukemia HL-60 cells.Q54559220
Autophagy is increased in mice after traumatic brain injury and is detectable in human brain after trauma and critical illnessQ61718222
Tetrahydrocurcumin confers protection against amyloid β-induced toxicityQ82659802
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
autophagyQ288322
apoptotic processQ14599311
traumatic brain injuryQ1995526
traumatic stressQ16920843
P304page(s)887-899
P577publication date2017-03-15
P1433published inAmerican Journal of Translational ResearchQ4744272
P1476titleTetrahydrocurcumin reduces oxidative stress-induced apoptosis via the mitochondrial apoptotic pathway by modulating autophagy in rats after traumatic brain injury
P478volume9

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cites work (P2860)
Q9201786724S-Hydroxycholesterol Is Associated with Agitation Severity in Patients with Moderate-to-Severe Alzheimer's Disease: Analyses from a Clinical Trial with Nabilone
Q55228013Autophagy in Traumatic Brain Injury: A New Target for Therapeutic Intervention.
Q91706717Curcumin Mitigates Neuro-Inflammation by Modulating Microglia Polarization Through Inhibiting TLR4 Axis Signaling Pathway Following Experimental Subarachnoid Hemorrhage
Q90721769Curcumin, Gut Microbiota, and Neuroprotection
Q55282902Ketamine ameliorates oxidative stress-induced apoptosis in experimental traumatic brain injury via the Nrf2 pathway.
Q92442619Neuroprotective Effects of Tetrahydrocurcumin against Glutamate-Induced Oxidative Stress in Hippocampal HT22 Cells
Q58583901Omega-3 polyunsaturated fatty acid attenuates traumatic brain injury-induced neuronal apoptosis by inducing autophagy through the upregulation of SIRT1-mediated deacetylation of Beclin-1
Q57170806Pathophysiology and treatment of cerebral edema in traumatic brain injury
Q92946992Potential Roles of NIX/BNIP3L Pathway in Rat Traumatic Brain Injury
Q58699554Recombinant milk fat globule-EGF factor-8 reduces apoptosis via integrin β3/FAK/PI3K/AKT signaling pathway in rats after traumatic brain injury
Q47696813Sinomenine reduces neuronal cell apoptosis in mice after traumatic brain injury via its effect on mitochondrial pathway
Q53396360The protective effects of crocin in the management of neurodegenerative diseases: a review.
Q88500302The role of autophagy in acute brain injury: A state of flux?
Q91893765Traumatic Brain Injuries: Pathophysiology and Potential Therapeutic Targets
Q55375016Valproic Acid Attenuates Traumatic Brain Injury-Induced Inflammation in Vivo: Involvement of Autophagy and the Nrf2/ARE Signaling Pathway.

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